hexamethonium has been researched along with Inflammation in 7 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 8.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
| "This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 4.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
| ") on upper gastrointestinal transit in control mice and in mice with chronic intestinal inflammation induced by croton oil." | 3.71 | Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice. ( Capasso, F; Capasso, R; Di Marzo, V; Fezza, F; Izzo, AA; Mascolo, N; Pinto, A, 2001) |
| "1." | 1.31 | Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. ( Benowitz, NL; Levine, JD; Miao, FJ, 2001) |
| "In hexamethonium-pretreated animals, an atropine-sensitive component of [betaAla(8)]NKA(4-10)-induced colonic contractions was also evident." | 1.31 | Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. ( Carini, F; Giuliani, S; Lecci, A; Maggi, CA; Tramontana, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ferreira, MJ | 1 |
| Santos Ferreira Silva, MPD | 1 |
| da Silva Dias, D | 1 |
| Bernardes, N | 1 |
| Irigoyen, MC | 1 |
| De Angelis, K | 1 |
| Svensson, L | 1 |
| Bergquist, J | 1 |
| Wennerås, C | 1 |
| Yoon, SY | 1 |
| Kim, HW | 1 |
| Roh, DH | 1 |
| Kwon, YB | 1 |
| Jeong, TO | 1 |
| Han, HJ | 1 |
| Lee, HJ | 1 |
| Choi, SM | 1 |
| Ryu, YH | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
| Tsukamoto, M | 1 |
| Sarna, SK | 1 |
| Condon, RE | 1 |
| Miao, FJ | 1 |
| Benowitz, NL | 1 |
| Levine, JD | 1 |
| Carini, F | 1 |
| Lecci, A | 1 |
| Tramontana, M | 1 |
| Giuliani, S | 1 |
| Maggi, CA | 1 |
| Capasso, R | 1 |
| Izzo, AA | 1 |
| Fezza, F | 1 |
| Pinto, A | 1 |
| Capasso, F | 1 |
| Mascolo, N | 1 |
| Di Marzo, V | 1 |
7 other studies available for hexamethonium and Inflammation
| Article | Year |
|---|---|
Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause.
Topics: Animals; Baroreflex; Blood Pressure; Female; Heart Rate; Hexamethonium; Hydrochlorothiazide; Hyperte | 2023 |
Neuromodulation of experimental Shigella infection reduces damage to the gut mucosa.
Topics: Animals; Calcitonin Gene-Related Peptide; Dysentery, Bacillary; Galanin; Hexamethonium; Inflammation | 2004 |
The anti-inflammatory effect of peripheral bee venom stimulation is mediated by central muscarinic type 2 receptors and activation of sympathetic preganglionic neurons.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Atropine; Autonomic Fibers, Preganglionic; Bee | 2005 |
A novel motility effect of tachykinins in normal and inflamed colon.
Topics: Animals; Atropine; Colon; Dogs; Female; Hexamethonium; Inflammation; Infusions, Intra-Arterial; Male | 1997 |
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine.
Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Respon | 2001 |
Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study.
Topics: Acetic Acid; Animals; Atropine; Cholinergic Fibers; Colon; Enzyme Inhibitors; Gastrointestinal Motil | 2001 |
Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice.
Topics: Adrenergic alpha-Antagonists; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Camphanes; C | 2001 |