hexamethonium has been researched along with Hypotension, Orthostatic in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 7.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
| "Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 3.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STUPPY, LJ | 1 |
| Funakami, Y | 1 |
| Hata, T | 1 |
| Itoh, E | 1 |
| Itano, S | 1 |
| Yamazaki, R | 1 |
| Tsuchida, K | 1 |
| Otomo, S | 1 |
3 other studies available for hexamethonium and Hypotension, Orthostatic
| Article | Year |
|---|---|
Hexamethonium and hydralazine hydrochloride for treatment of hypertension.
Topics: Cardiovascular Agents; Constipation; Hexamethonium; Hydralazine; Hypertension; Hypotension, Orthosta | 1954 |
Effects of some beta-adrenoceptor antagonists on orthostatic hypotension in repeatedly cold- (SART-) stressed rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cold Tempe | 2007 |
Effects of dihydroergotamine and etilefrine on experimentally-induced postural hypotension in dogs.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Dihydroergotamine; Dog | 1990 |