hexamethonium has been researched along with Hypertension, Malignant in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Production of malignant hypertension was affected by occlusion of one of the adjustable renal clips 3 weeks after BRC." | 1.27 | Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension. ( Brosnihan, KB; Ferrario, CM; Saruta, T; Suzuki, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROQUE, JA | 1 |
| CRUMPTON, CW | 1 |
| ROWE, GG | 1 |
| CAPPS, RC | 1 |
| WHITMORE, JJ | 1 |
| MURPHY, QR | 1 |
| Suzuki, H | 1 |
| Saruta, T | 1 |
| Ferrario, CM | 1 |
| Brosnihan, KB | 1 |
3 other studies available for hexamethonium and Hypertension, Malignant
| Article | Year |
|---|---|
Hexamethonium and apresoline (L-hydrazinophthalazine) in the treatment of malignant hypertension; report of a case.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Rel | 1954 |
The effect of hexamethonium upon cerebral blood flow and metabolism in patients with premalignant and malignant hypertension.
Topics: Brain; Cerebrovascular Circulation; Hexamethonium; Humans; Hypertension; Hypertension, Malignant; Mu | 1955 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Ca | 1987 |