hexamethonium has been researched along with Hemorrhagic Shock in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An increase in endogenous central histamine concentration after inhibition of histamine N-methyltransferase (HNMT) activity reverses critical hypotension and improves the survival of rats in haemorrhagic shock." | 7.72 | Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentration after inhibition of histamine N-methyltransferase (HNMT) activity reverses critical hypotension and improves the survival of rats in haemorrhagic shock." | 3.72 | Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats. ( Jochem, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jochem, J | 1 |
| Gunther, B | 1 |
| Vivaldi, E | 1 |
| Hellman, A | 1 |
| Lundberg, D | 1 |
3 other studies available for hexamethonium and Hemorrhagic Shock
| Article | Year |
|---|---|
Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine Derivatives; Blood Pres | 2004 |
Effects of ganglionic and alpha adrenergic blocking agents on the hemorrhagic shock in dogs.
Topics: Animals; Blood Pressure; Dibenzylchlorethamine; Dogs; Hexamethonium; Hexamethonium Compounds; Phenox | 1980 |
Hemodynamic effects of high doses of corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Bretylium Compounds; Cardiac Output; Dogs; Hemodynamics; Hexametho | 1985 |