hexamethonium has been researched along with Goldblatt Syndrome in 4 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Production of malignant hypertension was affected by occlusion of one of the adjustable renal clips 3 weeks after BRC." | 1.27 | Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension. ( Brosnihan, KB; Ferrario, CM; Saruta, T; Suzuki, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergamaschi, C | 1 |
| Campos, RR | 1 |
| Schor, N | 1 |
| Lopes, OU | 1 |
| Leenen, FH | 1 |
| Prowse, S | 1 |
| Suzuki, H | 1 |
| Saruta, T | 1 |
| Ferrario, CM | 1 |
| Brosnihan, KB | 1 |
| Nakada, T | 1 |
| Koike, H | 1 |
| Katayama, T | 1 |
4 other studies available for hexamethonium and Goldblatt Syndrome
| Article | Year |
|---|---|
Role of the rostral ventrolateral medulla in maintenance of blood pressure in rats with Goldblatt hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; | 1995 |
Time-course of changes in cardiac hypertrophy and pressor mechanisms in two-kidney, one clip hypertensive rats during treatment with minoxidil, enalapril or after uninephrectomy.
Topics: Animals; Blood Pressure; Blood Volume; Cardiac Volume; Cardiomegaly; Catecholamines; Enalapril; Hear | 1987 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Ca | 1987 |
Central noradrenergic neurons and vascular non-collagen protein in the initial phase of two-kidney, one-clip renovascular hypertension.
Topics: Animals; Aorta; Blood Pressure; Blood Vessels; Body Weight; Catecholamines; Dopamine; Hexamethonium; | 1988 |