hexamethonium has been researched along with Gastroparesis in 2 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Gastroparesis: Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colitis was induced 72 h prior to experiments using trinitrobenzene sulphate (TNBS) instillation." | 1.34 | Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve. ( De Man, JG; De Schepper, HU; De Winter, BY; Herman, AG; Pelckmans, PA; Timmermans, JP; Van Nassauw, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Jonge, WJ | 1 |
| van den Wijngaard, RM | 1 |
| The, FO | 1 |
| ter Beek, ML | 1 |
| Bennink, RJ | 1 |
| Tytgat, GN | 1 |
| Buijs, RM | 1 |
| Reitsma, PH | 1 |
| van Deventer, SJ | 1 |
| Boeckxstaens, GE | 1 |
| De Schepper, HU | 1 |
| De Man, JG | 1 |
| Van Nassauw, L | 1 |
| Timmermans, JP | 1 |
| Herman, AG | 1 |
| Pelckmans, PA | 1 |
| De Winter, BY | 1 |
2 other studies available for hexamethonium and Gastroparesis
| Article | Year |
|---|---|
Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice.
Topics: Animals; Enteric Nervous System; Female; Ganglionic Blockers; Gastric Emptying; Gastric Fundus; Gast | 2003 |
Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Capsaicin; Colitis; Ganglia, Spinal; Ganglionic Bl | 2007 |