hexamethonium has been researched along with Fasting Hypoglycemia in 11 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, it is not known to what extent increased glucagon secretion during hypoglycemia in mice is neurally mediated vs." | 7.68 | Autonomic control of pancreatic polypeptide and glucagon secretion during neuroglucopenia and hypoglycemia in mice. ( Ahren, B; Akpan, JO; Curry, DL; Gingerich, RL; Havel, PJ; Stern, JS, 1993) |
| "To determine the role of the autonomic nervous system (ANS) in mediating the glucagon response to marked insulin-induced hypoglycemia in dogs, we measured arterial and pancreatic venous glucagon responses to insulin-induced hypoglycemia during acute, terminal experiments in halothane-anesthetized dogs in which the ANS was intact (control; n = 9), pharmacologically blocked by the nicotinic ganglionic antagonist hexamethonium (n = 6), or surgically ablated by cervical vagotomy and cervical spinal cord section (n = 6)." | 7.68 | Role for autonomic nervous system to increase pancreatic glucagon secretion during marked insulin-induced hypoglycemia in dogs. ( Dunning, BE; Havel, PJ; Taborsky, GJ; Veith, RC, 1991) |
| " In addition, it is not known to what extent increased glucagon secretion during hypoglycemia in mice is neurally mediated vs." | 3.68 | Autonomic control of pancreatic polypeptide and glucagon secretion during neuroglucopenia and hypoglycemia in mice. ( Ahren, B; Akpan, JO; Curry, DL; Gingerich, RL; Havel, PJ; Stern, JS, 1993) |
| "To investigate the neural regulation of pancreatic polypeptide (PP) secretion during hypoglycemia in the rat, insulin was administered to chronically cannulated rats, and plasma PP responses were compared between saline-treated animals and animals pretreated with a ganglionic blocking agent (hexamethonium), a muscarinic antagonist (atropine), combined alpha- and beta-adrenergic receptor blockade (propranolol + tolazoline), or combined adrenergic blockade + atropine." | 3.68 | Autonomic nervous system mediation of the pancreatic polypeptide response to insulin-induced hypoglycemia in conscious rats. ( Akpan, JO; Curry, DL; Gingerich, RL; Havel, PJ; Parry, SJ; Stern, JS, 1992) |
| "To determine the role of the autonomic nervous system (ANS) in mediating the glucagon response to marked insulin-induced hypoglycemia in dogs, we measured arterial and pancreatic venous glucagon responses to insulin-induced hypoglycemia during acute, terminal experiments in halothane-anesthetized dogs in which the ANS was intact (control; n = 9), pharmacologically blocked by the nicotinic ganglionic antagonist hexamethonium (n = 6), or surgically ablated by cervical vagotomy and cervical spinal cord section (n = 6)." | 3.68 | Role for autonomic nervous system to increase pancreatic glucagon secretion during marked insulin-induced hypoglycemia in dogs. ( Dunning, BE; Havel, PJ; Taborsky, GJ; Veith, RC, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BILLINGTON, BP | 1 |
| PATON, A | 1 |
| REYNOLDS, TB | 1 |
| SHERLOCK, S | 1 |
| JUDSON, WE | 1 |
| HOLLANDER, W | 1 |
| MARLEY, E | 1 |
| YAMASHITA, K | 1 |
| SCHACHTER, M | 1 |
| LAURENCE, DR | 1 |
| STACEY, RS | 1 |
| Havel, PJ | 4 |
| Akpan, JO | 2 |
| Curry, DL | 2 |
| Stern, JS | 2 |
| Gingerich, RL | 2 |
| Ahren, B | 1 |
| Parry, SJ | 1 |
| Mundinger, TO | 1 |
| Veith, RC | 2 |
| Dunning, BE | 2 |
| Taborsky, GJ | 2 |
| Zhou, XF | 1 |
| Jhamandas, KH | 1 |
| Livett, BG | 1 |
11 other studies available for hexamethonium and Fasting Hypoglycemia
| Article | Year |
|---|---|
The effect of hexamethonium bromide on the circulatory and metabolic response to insulin hypoglycemia in man.
Topics: Hexamethonium; Humans; Hypoglycemia; Insulin; Male; Muscle Relaxants, Central; Pancreatic Diseases | 1954 |
The effects of insulin-induced hypoglycemia in patients with angina pectoris; before and after intravenous hexamethonium.
Topics: Angina Pectoris; Cardiovascular Agents; Hexamethonium; Humans; Hyperinsulinism; Hypoglycemia; Insuli | 1956 |
Modification of hypoglycaemia with hexamethonium bromide.
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hypoglycemia; Insulin; Pancreatic Diseases | 1957 |
Effect of hexamethonium on the augmented adrenaline secretion of the adrenal gland causable by insulin hypoglycemia.
Topics: Adrenal Glands; Epinephrine; Hexamethonium; Hexamethonium Compounds; Hyperinsulinism; Hypoglycemia; | 1957 |
Hexamethonium and insulin hypoglycaemia.
Topics: Hexamethonium; Humans; Hyperinsulinism; Hypoglycemia; Insulin Antagonists; Insulins; Muscle Relaxant | 1951 |
Effect of hexamethonium on the response to insulin in animals and man.
Topics: Animals; Cardiovascular Agents; Hexamethonium; Humans; Hypoglycemia; Insulin; Male; Muscle Relaxants | 1952 |
Autonomic control of pancreatic polypeptide and glucagon secretion during neuroglucopenia and hypoglycemia in mice.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Glucose; Brain Diseases; Eating; Female; Glucagon | 1993 |
Autonomic nervous system mediation of the pancreatic polypeptide response to insulin-induced hypoglycemia in conscious rats.
Topics: Animals; Autonomic Nervous System; Blood Glucose; Hexamethonium; Hexamethonium Compounds; Hypoglycem | 1992 |
Corelease of galanin and NE from pancreatic sympathetic nerves during severe hypoglycemia in dogs.
Topics: Animals; Blood Glucose; Denervation; Dogs; Galanin; Ganglionic Blockers; Glucagon; Hexamethonium; He | 1992 |
Role for autonomic nervous system to increase pancreatic glucagon secretion during marked insulin-induced hypoglycemia in dogs.
Topics: Animals; Autonomic Nervous System; Blood Glucose; Dogs; Epinephrine; Glucagon; Hematocrit; Hexametho | 1991 |
Capsaicin-sensitive nerves are required for glucostasis but not for catecholamine output during hypoglycemia in rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Capsaicin; Epinephrine; Hexamethonium; Hexame | 1990 |