hexamethonium has been researched along with Colitis, Ulcerative in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicotine has been shown to reduce both tone and muscular activity in the human colon by releasing nitric oxide (NO) from nerves." | 1.35 | Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis. ( Fujino, H; Hamada, Y; Horie, S; Murakami, I; Murayama, T; Yamane, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salaga, M | 1 |
| Blomster, LV | 1 |
| Piechota-Polańczyk, A | 1 |
| Zielińska, M | 1 |
| Jacenik, D | 1 |
| Cygankiewicz, AI | 1 |
| Krajewska, WM | 1 |
| Mikkelsen, JD | 1 |
| Fichna, J | 1 |
| Murakami, I | 1 |
| Hamada, Y | 1 |
| Yamane, S | 1 |
| Fujino, H | 1 |
| Horie, S | 1 |
| Murayama, T | 1 |
| HURLEY, JW | 1 |
| KNOWLTON, NP | 1 |
| WALL, ED | 1 |
3 other studies available for hexamethonium and Colitis, Ulcerative
| Article | Year |
|---|---|
Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Flow | 2016 |
Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis.
Topics: Animals; Atropine; Bethanechol; Colitis, Ulcerative; Colon; Colon, Descending; Colon, Transverse; De | 2009 |
Hexamethonium in the treatment of ulcerative colitis: report of a case.
Topics: Colitis; Colitis, Ulcerative; Hexamethonium; Humans; Muscle Relaxants, Central | 1954 |