Page last updated: 2024-10-28

hexamethonium and Cerebellar Ataxia

hexamethonium has been researched along with Cerebellar Ataxia in 2 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, AD2
Dar, MS2

Other Studies

2 other studies available for hexamethonium and Cerebellar Ataxia

ArticleYear
Mouse cerebellar nicotinic-cholinergic receptor modulation of Delta9-THC ataxia: role of the alpha4beta2 subtype.
    Brain research, 2006, Oct-18, Volume: 1115, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cannabinoid Receptor Agonists; Cerebellar Ataxia;

2006
Behavioral cross-tolerance between repeated intracerebellar nicotine and acute Delta(9)-tetrahydrocannabinol-induced cerebellar ataxia: role of cerebellar nitric oxide.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: Animals; Cerebellar Ataxia; Cerebellum; Dihydro-beta-Erythroidine; Dronabinol; Drug Tolerance; Hexam

2007