hexamethonium has been researched along with Cardiomegaly in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac hypertrophy was observed in both treated groups (P<0." | 1.33 | Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats. ( Bergamaschi, CT; Beutel, A; Campos, RR, 2005) |
| "Treatment with hydralazine did not affect left ventricular weight and caused a small increase in the weight of the right ventricle." | 1.27 | Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats. ( Leenen, FH; Tsoporis, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beutel, A | 1 |
| Bergamaschi, CT | 1 |
| Campos, RR | 1 |
| Leenen, FH | 2 |
| Prowse, S | 1 |
| Tsoporis, J | 1 |
3 other studies available for hexamethonium and Cardiomegaly
| Article | Year |
|---|---|
Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats.
Topics: Anabolic Agents; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Cardiac Output; Card | 2005 |
Time-course of changes in cardiac hypertrophy and pressor mechanisms in two-kidney, one clip hypertensive rats during treatment with minoxidil, enalapril or after uninephrectomy.
Topics: Animals; Blood Pressure; Blood Volume; Cardiac Volume; Cardiomegaly; Catecholamines; Enalapril; Hear | 1987 |
Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats.
Topics: Animals; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; Epinephrine; Heart; Heart Rate; He | 1988 |