hexamethonium has been researched along with Cardiac Hypertrophy in 3 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac hypertrophy was observed in both treated groups (P<0." | 1.33 | Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats. ( Bergamaschi, CT; Beutel, A; Campos, RR, 2005) |
| "Treatment with hydralazine did not affect left ventricular weight and caused a small increase in the weight of the right ventricle." | 1.27 | Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats. ( Leenen, FH; Tsoporis, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beutel, A | 1 |
| Bergamaschi, CT | 1 |
| Campos, RR | 1 |
| Leenen, FH | 2 |
| Prowse, S | 1 |
| Tsoporis, J | 1 |
3 other studies available for hexamethonium and Cardiac Hypertrophy
| Article | Year |
|---|---|
Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats.
Topics: Anabolic Agents; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Cardiac Output; Card | 2005 |
Time-course of changes in cardiac hypertrophy and pressor mechanisms in two-kidney, one clip hypertensive rats during treatment with minoxidil, enalapril or after uninephrectomy.
Topics: Animals; Blood Pressure; Blood Volume; Cardiac Volume; Cardiomegaly; Catecholamines; Enalapril; Hear | 1987 |
Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats.
Topics: Animals; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; Epinephrine; Heart; Heart Rate; He | 1988 |