hexamethonium has been researched along with Cardiac Failure in 12 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two signatures of heart failure are activation of the sympathetic nervous system and catecholamine desensitization." | 1.30 | Effects of cardiac denervation on development of heart failure and catecholamine desensitization. ( Asai, K; Ghaleh-Marzban, B; Kudej, RK; Mirsky, I; Patrick, TA; Sato, N; Shannon, RP; Shen, YT; Uechi, M; Vatner, DE; Vatner, SF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KELLEY, RT | 1 |
| FREIS, ED | 3 |
| HIGGINS, TF | 1 |
| WILSON, AG | 1 |
| WILSON, VH | 1 |
| KEELEY, KJ | 1 |
| BURCH, RR | 1 |
| PHILLIPS, JH | 1 |
| ULLMANN, TD | 1 |
| MENCZEL, J | 1 |
| Burch, GE | 1 |
| Brändle, M | 1 |
| Patel, KP | 1 |
| Wang, W | 1 |
| Zucker, IH | 1 |
| Sato, N | 1 |
| Vatner, SF | 1 |
| Shen, YT | 1 |
| Kudej, RK | 1 |
| Ghaleh-Marzban, B | 1 |
| Uechi, M | 1 |
| Asai, K | 1 |
| Mirsky, I | 1 |
| Patrick, TA | 1 |
| Shannon, RP | 1 |
| Vatner, DE | 1 |
| Neumann, T | 1 |
| Ravens, U | 1 |
| Heusch, G | 1 |
12 other studies available for hexamethonium and Cardiac Failure
| Article | Year |
|---|---|
The effects of hexamethonium on certain manifestations of congestive heart failure.
Topics: Cardiovascular Agents; Heart Failure; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Effect of hexamethonium on normotensive heart failure; a possible correlation between the mechanism of essential hypertension and normotensive heart failure.
Topics: Essential Hypertension; Heart Failure; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The haemodynamic effects of hexamethonium bromide in patients with pulmonary hypertension and heart failure.
Topics: Blood Circulation; Heart Failure; Hemodynamics; Hexamethonium; Hypertension; Hypertension, Pulmonary | 1953 |
The effects of intravenous hexamethonium on venous pressure of normotensive and hypertensive patients with and without congestive heart failure.
Topics: Blood Pressure; Blood Pressure Determination; Heart Failure; Hexamethonium; Humans; Hypertension; Ve | 1955 |
The lymphatic system, with particular reference to cardiac edema; an experimental study of the lymphodynamic effects of hexamethonium.
Topics: Cortisone; Edema; Edema, Cardiac; Heart Failure; Hexamethonium; Humans; Lymph; Lymphatic System; Mus | 1955 |
The effect of a ganglionic blocking agent (hexamethonium) on renal function and on excretion of water and electrolytes in hypertension and in congestive heart failure.
Topics: Electrolytes; Ganglionic Blockers; Heart Failure; Hexamethonium; Humans; Hypertension; Kidney Functi | 1956 |
Preload and afterload reduction in treating congestive heart failure.
Topics: Autonomic Nerve Block; Heart Failure; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; | 1984 |
The digital circulation in congestive heart failure.
Topics: Air Conditioning; Blood Circulation; Conditioning, Classical; Dose-Response Relationship, Drug; Envi | 1983 |
Hemodynamic and norepinephrine responses to pacing-induced heart failure in conscious sinoaortic-denervated dogs.
Topics: Animals; Blood Pressure; Cardiac Pacing, Artificial; Cholinergic Antagonists; Dogs; Female; Heart Fa | 1996 |
Effects of cardiac denervation on development of heart failure and catecholamine desensitization.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Atropine Derivatives; Blood Pressure; | 1997 |
Characterization of excitation-contraction coupling in conscious dogs with pacing-induced heart failure.
Topics: Animals; Atropine; Cardiac Pacing, Artificial; Dogs; Echocardiography; Electric Stimulation; Female; | 1998 |
Hexamethonium, a forgotten drug in relation to "new" concepts in the management of heart failure.
Topics: Ganglionic Blockers; Heart Failure; Hexamethonium; Hexamethonium Compounds; Humans | 1989 |