hexamethonium has been researched along with Brain Ischemia in 6 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study investigated the bradycardiac responses to brain ischemia for approximately 30s before and after intravenous administration of hexamethonium (C6, 15 mg/kg) in urethane-anesthetized spontaneously breathing rabbits." | 7.68 | Effects of hexamethonium on bradycardiac responses to brain ischemia in the rabbit. ( Kanno, T; Matsumoto, S; Nagayama, T; Shimizu, T; Yamasaki, M, 1992) |
| "The present study investigated the bradycardiac responses to brain ischemia for approximately 30s before and after intravenous administration of hexamethonium (C6, 15 mg/kg) in urethane-anesthetized spontaneously breathing rabbits." | 3.68 | Effects of hexamethonium on bradycardiac responses to brain ischemia in the rabbit. ( Kanno, T; Matsumoto, S; Nagayama, T; Shimizu, T; Yamasaki, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horiuchi, J | 1 |
| Takeuchi, T | 1 |
| Shu, CC | 1 |
| Hoffman, WE | 2 |
| Thomas, C | 2 |
| Albrecht, RF | 2 |
| Skarphedinsson, JO | 1 |
| Delle, M | 1 |
| Carlsson, S | 1 |
| Bealer, SL | 1 |
| Matsumoto, S | 1 |
| Yamasaki, M | 1 |
| Kanno, T | 1 |
| Nagayama, T | 1 |
| Shimizu, T | 1 |
| Werner, C | 1 |
| Miletich, DJ | 1 |
| Prabhakar, NR | 1 |
| Mitra, J | 1 |
| Van de Graaff, W | 1 |
| Haxhiu, MA | 1 |
| Cherniack, NS | 1 |
6 other studies available for hexamethonium and Brain Ischemia
| Article | Year |
|---|---|
Descending pathways of powerful pressor response elicited by suprapontine cerebral ischemia in rabbits.
Topics: Animals; Blood Pressure; Brain Ischemia; Brain Stem; Denervation; Efferent Pathways; Female; Ganglio | 1994 |
Sympathetic activity enhances glucose-related ischemic injury in the rat.
Topics: Animals; Blood Glucose; Brain Ischemia; Epinephrine; Ganglionic Blockers; Hexamethonium; Hexamethoni | 1993 |
The effects of hexamethonium on cerebral blood flow and cerebral function during relative cerebral ischaemia in rats.
Topics: Animals; Blood Pressure; Brain Ischemia; Brain Stem; Cerebral Hemorrhage; Cerebrovascular Circulatio | 1996 |
Effects of hexamethonium on bradycardiac responses to brain ischemia in the rabbit.
Topics: Animals; Bradycardia; Brain Ischemia; Electric Stimulation; Evoked Potentials; Ganglionic Blockers; | 1992 |
Ganglionic blockade improves neurologic outcome from incomplete ischemia in rats: partial reversal by exogenous catecholamines.
Topics: Animals; Behavior, Animal; Blood Glucose; Brain; Brain Ischemia; Carbon Dioxide; Catecholamines; Epi | 1990 |
Effect of focal cooling of central chemosensitive areas on cerebral ischemic response.
Topics: Administration, Topical; Anesthesia, Local; Animals; Atropine; Blood Pressure; Brain; Brain Ischemia | 1986 |