Page last updated: 2024-10-28

hexamethonium and Body Weight

hexamethonium has been researched along with Body Weight in 19 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"This study was conducted to examine if central amiloride-sensitive transport systems are involved in the development and/or maintenance of hypertension in spontaneously hypertensive rats (SHR)."7.71Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats. ( Akahoshi, M; Kitamura, S; Nagao, S; Nonaka, M; Seto, S; Yano, K, 2001)
"To explore the pathophysiological role of leptin in obesity-related hypertension, we examined cardiovascular phenotypes of transgenic skinny mice whose elevated plasma leptin concentrations are comparable to those seen in obese subjects."7.70Pathophysiological role of leptin in obesity-related hypertension. ( Aizawa-Abe, M; Ebihara, K; Hayashi, T; Hosoda, K; Inoue, G; Iwai, H; Masuzaki, H; Matsuoka, N; Nakao, K; Ogawa, Y; Satoh, N; Yoshimasa, Y, 2000)
"This study was conducted to examine if central amiloride-sensitive transport systems are involved in the development and/or maintenance of hypertension in spontaneously hypertensive rats (SHR)."3.71Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats. ( Akahoshi, M; Kitamura, S; Nagao, S; Nonaka, M; Seto, S; Yano, K, 2001)
"To explore the pathophysiological role of leptin in obesity-related hypertension, we examined cardiovascular phenotypes of transgenic skinny mice whose elevated plasma leptin concentrations are comparable to those seen in obese subjects."3.70Pathophysiological role of leptin in obesity-related hypertension. ( Aizawa-Abe, M; Ebihara, K; Hayashi, T; Hosoda, K; Inoue, G; Iwai, H; Masuzaki, H; Matsuoka, N; Nakao, K; Ogawa, Y; Satoh, N; Yoshimasa, Y, 2000)
"Cardiac hypertrophy was observed in both treated groups (P<0."1.33Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats. ( Bergamaschi, CT; Beutel, A; Campos, RR, 2005)
"Hypertension was induced in male Sprague-Dawley rats (n=40) by suprarenal aortic coarctation."1.30Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension. ( Casto, RM; DeMaria, JE; Overton, JM; VanNess, JM, 1998)
"Treatment with hexamethonium abolished the difference in RAP during acute volume infusion."1.29Preoptic recess lesions reduce right atrial pressure responses to volume expansion. ( Bealer, SL, 1996)
"Treatment with hydralazine did not affect left ventricular weight and caused a small increase in the weight of the right ventricle."1.27Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats. ( Leenen, FH; Tsoporis, J, 1988)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's3 (15.79)18.2507
2000's7 (36.84)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xue, B1
Badaue-Passos, D1
Guo, F1
Gomez-Sanchez, CE1
Hay, M1
Johnson, AK1
Moreira, TS1
Takakura, AC1
Colombari, E1
Menani, JV1
Beutel, A1
Bergamaschi, CT2
Campos, RR2
Freitas, RR1
Lopes, KL1
Carillo, BA1
Carmona, AK1
Casarini, DE1
Furukawa, L1
Heimann, JC1
Dolnikoff, MS1
Maeda, C1
Schaan, B1
Oliveira, E1
Oliveira, V1
De Angelis, K1
Irigoyen, M1
Bealer, SL1
VanNess, JM1
Casto, RM1
DeMaria, JE1
Overton, JM1
Aizawa-Abe, M1
Ogawa, Y1
Masuzaki, H1
Ebihara, K1
Satoh, N1
Iwai, H1
Matsuoka, N1
Hayashi, T1
Hosoda, K1
Inoue, G1
Yoshimasa, Y1
Nakao, K1
Seto, S1
Kitamura, S1
Nagao, S1
Nonaka, M1
Akahoshi, M1
Yano, K1
Zhou, XF1
Jhamandas, KH1
Livett, BG1
Lüscher, TF1
Vanhoutte, PM1
Toal, CB1
Leenen, FH4
Wilczynski, EA2
Bedford, TG1
Tipton, CM1
Tucker, DC1
Domino, JV1
Tsoporis, J1
Nakada, T1
Koike, H1
Katayama, T1
Lodato, RF1
Michael, JR1
Murray, PA1

Other Studies

19 other studies available for hexamethonium and Body Weight

ArticleYear
Sex differences and central protective effect of 17beta-estradiol in the development of aldosterone/NaCl-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Brain; Disease Models, Anim

2009
Antihypertensive effects of central ablations in spontaneously hypertensive rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Baroreflex; Blood Pressur

2009
Effects of chronic anabolic steroid treatment on tonic and reflex cardiovascular control in male rats.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 93, Issue:1

    Topics: Anabolic Agents; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Cardiac Output; Card

2005
Sympathetic and renin-angiotensin systems contribute to increased blood pressure in sucrose-fed rats.
    American journal of hypertension, 2007, Volume: 20, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Body Weight; Captop

2007
Chronic salt loading and cardiovascular-associated changes in experimental diabetes in rats.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arginine Vasopressin; Baroreflex; Blood Glucose; B

2007
Preoptic recess lesions reduce right atrial pressure responses to volume expansion.
    Journal of the autonomic nervous system, 1996, Sep-12, Volume: 60, Issue:3

    Topics: Animals; Atrial Function, Right; Blood Pressure; Body Weight; Cardiac Volume; Cerebral Ventricles; H

1996
Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aortic Coarctation; Atropine; Blood Glucose; Blood Pressure; Bod

1998
Pathophysiological role of leptin in obesity-related hypertension.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; alpha-MSH; Animals; Blood Pressure; Body

2000
Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats.
    Brain research, 2001, Jul-06, Volume: 906, Issue:1-2

    Topics: Amiloride; Angiotensin II; Animals; Blood Pressure; Body Weight; Brain; Carrier Proteins; Diuretics;

2001
Capsaicin-sensitive nerves are required for glucostasis but not for catecholamine output during hypoglycemia in rats.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 1

    Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Capsaicin; Epinephrine; Hexamethonium; Hexame

1990
Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Cytochrome P-450 Enzyme System

1986
Dietary sodium restriction, blood pressure and sympathetic activity in spontaneously hypertensive rats.
    Journal of hypertension, 1987, Volume: 5, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Epinephrine; Ganglia, Sympathetic; He

1987
Prevention of hypertension and maintenance of normotension in spontaneously hypertensive rats is dependent on continuous severe dietary sodium restriction.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:4

    Topics: Aging; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Eating; Hexamethonium; Hexamet

1987
Dietary sodium intake and age in spontaneously hypertensive rats: effects on blood pressure and sympathetic activity.
    Life sciences, 1987, Aug-10, Volume: 41, Issue:6

    Topics: Aging; Animals; Blood Pressure; Body Weight; Catecholamines; Diet, Sodium-Restricted; Growth Disorde

1987
Exercise training and the arterial baroreflex.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:5

    Topics: Animals; Blood Pressure; Body Weight; Carotid Sinus; Hexamethonium; Hexamethonium Compounds; Ligatio

1987
Balance among autonomic controls of heart rate in neonatal spontaneously hypertensive and borderline hypertensive rats.
    Journal of the autonomic nervous system, 1988, Volume: 22, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Antihypertensive Agents; Atenolol; Atropine Derivatives; Aut

1988
Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4

    Topics: Animals; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; Epinephrine; Heart; Heart Rate; He

1988
Central noradrenergic neurons and vascular non-collagen protein in the initial phase of two-kidney, one-clip renovascular hypertension.
    International urology and nephrology, 1988, Volume: 20, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Blood Vessels; Body Weight; Catecholamines; Dopamine; Hexamethonium;

1988
Absence of neural modulation of hypoxic pulmonary vasoconstriction in conscious dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:4

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Body Weight; Cardiac Output; Constriction; Dogs;

1988