hexamethonium has been researched along with Apnea in 5 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate the importance of sympathoadrenal activation in the acute cardiovascular response to apneas and the role of hypoxemia in this response." | 7.70 | Mechanisms of acute cardiovascular response to periodic apneas in sedated pigs. ( Chen, L; Scharf, SM; Sica, AL, 1999) |
| "This study was designed to evaluate the importance of sympathoadrenal activation in the acute cardiovascular response to apneas and the role of hypoxemia in this response." | 3.70 | Mechanisms of acute cardiovascular response to periodic apneas in sedated pigs. ( Chen, L; Scharf, SM; Sica, AL, 1999) |
| "After saline pretreatment, response to 5-HT consisted of immediate and brief apnea, bradycardia, and hypotension, followed by sustained tachypnea, tachycardia, pulmonary hypertension, and hypocapnic hypoxemia." | 3.69 | Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves. ( Amory, H; Desmecht, DJ; Lekeux, PM; Linden, AS, 1996) |
| " In 11 of 13 dogs studied, reproducible responses of either apnea (n = 9) or rapid shallow breathing (n = 2) were elicited immediately after the first or second breath of smoke inhalation: apneic duration reached 398 +/- 47% (mean +/- SEM) of the mean baseline expiratory duration." | 3.67 | Hexamethonium aerosol prevents pulmonary reflexes induced by cigarette smoke in dogs. ( Lee, LY; Morton, RF, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niane, LM | 1 |
| Joseph, V | 1 |
| Bairam, A | 1 |
| Linden, AS | 1 |
| Desmecht, DJ | 1 |
| Amory, H | 1 |
| Lekeux, PM | 1 |
| Chen, L | 1 |
| Sica, AL | 1 |
| Scharf, SM | 1 |
| Lee, LY | 2 |
| Morton, RF | 2 |
| Kou, YR | 1 |
5 other studies available for hexamethonium and Apnea
| Article | Year |
|---|---|
Systemic blockade of nicotinic and purinergic receptors inhibits ventilation and increases apnoea frequency in newborn rats.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Drug Therapy, Combination; Female; Hexamethonium; | 2012 |
Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves.
Topics: Aging; Animals; Apnea; Atropine; Bradycardia; Cattle; Cattle Diseases; Cholinergic Agents; Ganglioni | 1996 |
Mechanisms of acute cardiovascular response to periodic apneas in sedated pigs.
Topics: Anesthesia; Animals; Apnea; Blood Pressure; Cardiac Output; Epinephrine; Female; Heart Rate; Hemodyn | 1999 |
Acute effects of cigarette smoke on breathing in rats: vagal and nonvagal mechanisms.
Topics: Animals; Apnea; Chemoreceptor Cells; Hexamethonium; Hexamethonium Compounds; Nerve Fibers; Nicotine; | 1990 |
Hexamethonium aerosol prevents pulmonary reflexes induced by cigarette smoke in dogs.
Topics: Aerosols; Animals; Apnea; Cold Temperature; Dogs; Electric Stimulation; Hexamethonium; Hexamethonium | 1986 |