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hexamethonium and Aortic Coarctation

hexamethonium has been researched along with Aortic Coarctation in 1 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.

Research Excerpts

ExcerptRelevanceReference
"Hypertension was induced in male Sprague-Dawley rats (n=40) by suprarenal aortic coarctation."1.30Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension. ( Casto, RM; DeMaria, JE; Overton, JM; VanNess, JM, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
VanNess, JM1
Casto, RM1
DeMaria, JE1
Overton, JM1

Other Studies

1 other study available for hexamethonium and Aortic Coarctation

ArticleYear
Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aortic Coarctation; Atropine; Blood Glucose; Blood Pressure; Bod

1998