hexahydrosiladifenidol has been researched along with Muscle Contraction in 13 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of subtype-selective muscarinic receptor antagonists on electrically evoked release of acetylcholine and muscle contraction were compared in circular muscle preparations of the guinea-pig ileum." | 3.69 | Prejunctional M1 and postjunctional M3 muscarinic receptors in the circular muscle of the guinea-pig ileum. ( Dietrich, C; Kilbinger, H, 1995) |
| "Like atropine, BTM-1086 was a potent, nonselective, competitive muscarinic antagonist with no detectable antispasmodic activity in urinary bladder or ileal muscle." | 1.28 | In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues. ( Jackson, KN; Kachur, JF; Lowe, VC; Noronha-Blob, L; Sturm, BL, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 10 (76.92) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roffel, AF | 2 |
| Meurs, H | 1 |
| Elzinga, CR | 2 |
| Zaagsma, J | 2 |
| Dietrich, C | 1 |
| Kilbinger, H | 2 |
| Boselli, C | 1 |
| Grana, E | 1 |
| Kerr, PM | 1 |
| Hillier, K | 1 |
| Wallis, RM | 1 |
| Garland, CJ | 1 |
| Lau, WA | 1 |
| Pennefather, JN | 1 |
| Mitchelson, FJ | 1 |
| Mahesh, VK | 1 |
| Nunan, LM | 1 |
| Halonen, M | 1 |
| Yamamura, HI | 1 |
| Palmer, JD | 1 |
| Bloom, JW | 1 |
| Janssen, LJ | 1 |
| Daniel, EE | 1 |
| Jaiswal, N | 1 |
| Lambrecht, G | 2 |
| Mutschler, E | 2 |
| Tacke, R | 2 |
| Malik, KU | 1 |
| Rivera, L | 1 |
| Prieto, D | 1 |
| Hernández, M | 1 |
| Benedito, S | 1 |
| García-Sacristán, A | 1 |
| Noronha-Blob, L | 1 |
| Sturm, BL | 1 |
| Lowe, VC | 1 |
| Jackson, KN | 1 |
| Kachur, JF | 1 |
| Fuder, H | 2 |
| Schöpf, J | 1 |
| Unckell, J | 1 |
| Wesner, MT | 1 |
| Melchiorre, C | 1 |
| Müller, H | 1 |
13 other studies available for hexahydrosiladifenidol and Muscle Contraction
| Article | Year |
|---|---|
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide | 1995 |
Prejunctional M1 and postjunctional M3 muscarinic receptors in the circular muscle of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Choline; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic A | 1995 |
Mode of antagonism of methoctramine, AF-DX 116 and hexahydrosiladifenidol in guinea-pig left atrium and ileum: comparison of Schild and resultant analysis.
Topics: Animals; Diamines; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic An | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Dru | 1995 |
Cholinergic facilitation of neurotransmission to the smooth muscle of the guinea-pig prostate gland.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Guinea Pigs; Male; Mu | 2000 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardi | 1992 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds | 1990 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihy | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Gangli | 1991 |
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle.
Topics: Bronchi; Humans; In Vitro Techniques; Ipratropium; Muscle Contraction; Muscle, Smooth; Parasympathol | 1990 |
In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues.
Topics: Animals; Atropine; Calcium; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Musc | 1990 |
Different muscarine receptors mediate the prejunctional inhibition of [3H]-noradrenaline release in rat or guinea-pig iris and the contraction of the rabbit iris sphincter muscle.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Iris; Kinetics; Methacholine Compounds; Muscle C | 1989 |
Organ selectivity of hexahydrosiladifenidol in blocking pre- and postjunctional muscarinic receptors studied in guinea-pig ileum and rat heart.
Topics: Acetylcholine; Animals; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Male; Muscle Contraction; No | 1985 |