Page last updated: 2024-10-28

hexachlorophene and Nervous System Disorders

hexachlorophene has been researched along with Nervous System Disorders in 8 studies

Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Research Excerpts

ExcerptRelevanceReference
" There is much concern about the possible adverse effects of this population-wide low-level lead exposure, particularly on the developing organism, where the central nervous system may be a primary target for lead."1.27Some toxic effects of lead, other metals and antibacterial agents on the nervous system--animal experiment models. ( Björklund, H; Henschen, A; Hoffer, B; Olson, L; Palmer, M, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olson, L1
Björklund, H1
Henschen, A1
Palmer, M1
Hoffer, B1
Le Quesne, PM1
Kensit, JG1
Rose, AL1
Wiśniewski, HM1
Cammer, W1
Thompson, JP1
Senior, DF1
Pinson, DM1
Moriello, KA1
Schwartz, JF1
Ulsamer, AG1
O'Connell, MF1
Ippen, H1

Reviews

3 reviews available for hexachlorophene and Nervous System Disorders

ArticleYear
Neurotoxic substances.
    Modern trends in neurology, 1975, Volume: 6

    Topics: Acrylamides; Animals; Cats; Central Nervous System Diseases; Clioquinol; Environmental Exposure; Hex

1975
Hexachlorophane: toxicity and effectiveness in prevention of sepsis in neonatal units.
    The Journal of antimicrobial chemotherapy, 1975, Volume: 1, Issue:3

    Topics: Administration, Oral; Administration, Topical; Animals; Animals, Newborn; Baths; Child; Cross Infect

1975
Drug-induced neurologic disorders in childhood.
    Current problems in pediatrics, 1971, Volume: 1, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Amphetamine; Anesthesia, Inhalation; Anesthesia, Local; Animal

1971

Other Studies

5 other studies available for hexachlorophene and Nervous System Disorders

ArticleYear
Some toxic effects of lead, other metals and antibacterial agents on the nervous system--animal experiment models.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Adrenergic Fibers; Animals; Chlorhexidine; Female; Hexachlorophene; Iris; Lead Poisoning; Metals; Ne

1984
Neurotoxicity of hexachlorophene: new pathological and biochemical observations.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Animals; Animals, Newborn; Diarrhea; Female; Glutamates; Hexachlorophene; Malates; Maternal-Fetal Ex

1975
Neurotoxicosis associated with the use of hexachlorophene in a cat.
    Journal of the American Veterinary Medical Association, 1987, May-15, Volume: 190, Issue:10

    Topics: Animals; Cat Diseases; Cats; Female; Hexachlorophene; Nervous System Diseases

1987
Hexachlorophene induced myelin lesions in the developing nervous system of Xenopus tadpoles: morphological and biochemical observations.
    Journal of neuropathology and experimental neurology, 1974, Volume: 33, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Cell Nucleus; Central Nervous System; Centra

1974
[Neurotoxic effect of hexachlorophene].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:1

    Topics: Hexachlorophene; Humans; Infant, Newborn; Nervous System Diseases; Skin Absorption

1973