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hexachlorophene and Infection, Postoperative Wound

hexachlorophene has been researched along with Infection, Postoperative Wound in 35 studies

Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199032 (91.43)18.7374
1990's3 (8.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GERACI, CL1
HORVATH, M1
GIERHAKE, FW1
LAWRENCE, RR1
COLE, WR1
BERNARD, HR1
CONNELL, JF1
ROUSSELOT, LM1
NELSON, RM1
JENSON, CB1
PETERSON, CA1
SANDERS, BC1
WRIGHT, WK1
MARMESH, PJ1
Reilly, FC1
Crowder, VH1
Welsh, JS1
Bornside, GH1
Cohn, I1
Sebben, JE1
Kaul, AF1
Jewett, JF1
Ritter, MA1
French, ML1
Eitzen, HE1
Gioe, TJ1
Rudichenko, VF1
Volkova, VP1
Rudichenko, VM1
Lomonosov, SP1
Andreieshchev, SA1
Kalinichenko, LM1
Boĭko, EE1
Mozgunova, TI1
Morgan, JP1
Haug, RH1
Kosman, JW1
Sutherland, RD1
Martinez, HE1
Guynes, WA1
Miller, L1
Kourtopoulos, H1
Burman, LG1
Góral, R1
Kedzia, W1
Deja, A1
Muszyński, Z1
Meares, EM1
Noble, WC1
Zdeblick, TA1
Lederman, MM1
Jacobs, MR1
Marcus, RE1
Butler, HM1
Laver, JC1
Shulman, A1
Wright, RD1
Rebouillat, J1
Filliat, M1
Barber, HR1
Graber, EA1
Nowacki, M1
Jeziorski, J1
Kukawski, P1
Ballinger, WF1
Gravens, DL1
Margraf, HW1
Butcher, HR1
Shabanov, AN1
Odinets, EE1
Troshin, VM1
Panek, PH1
Prusak, MP1
Bolt, D1
Edlich, RF1
White, JJ1
Duncan, A1
Svãb, J1
Udrzal, F1
Bruun, JN1
Plotkina, NS3
Virnik, AD1
Snezhko, DL1
Pecora, DV1
Landis, RE1
Martin, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparison of Chlorhexadine Gluconate Versus Povidone Iodine Surgical Preparation in Skin Bacterial Colony Counts for Elective Knee Replacement Surgery[NCT01184196]Phase 455 participants (Actual)Interventional2009-11-30Terminated (stopped due to ChloroPrep Wipes no longer available)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for hexachlorophene and Infection, Postoperative Wound

ArticleYear
Agents and techniques for disinfection of the skin.
    Surgery, gynecology & obstetrics, 1981, Volume: 152, Issue:5

    Topics: Benzalkonium Compounds; Chlorhexidine; Disinfectants; Disinfection; Drug Contamination; Hexachloroph

1981
Antimicrobial skin preparations for the maxillofacial region.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:1

    Topics: 1-Propanol; Anti-Infective Agents, Local; Chlorhexidine; Cornea; Deafness; Dermatologic Agents; Etha

1996
Factors that influence surgical wound infections. Role of prophylactic antibiotic therapy.
    Urology, 1975, Volume: 6, Issue:5

    Topics: Age Factors; Ampicillin; Animals; Anti-Bacterial Agents; Bacitracin; Cephaloridine; Diabetes Complic

1975
Dispersal of skin microorganisms.
    The British journal of dermatology, 1975, Volume: 93, Issue:4

    Topics: Adult; Air Microbiology; Baths; Body Surface Area; Carbanilides; Cell Count; Clothing; Cross Infecti

1975
The intestinal tract in relation to obstetrics and gynecology.
    Clinical obstetrics and gynecology, 1972, Volume: 15, Issue:3

    Topics: Adolescent; Anti-Bacterial Agents; Baths; Drainage; Eating; Enema; Female; Genital Diseases, Female;

1972
[Current status of prevention of postoperative suppurative and septic complications in surgical clinics (literature review)].
    Khirurgiia, 1971, Volume: 47, Issue:1

    Topics: Anti-Bacterial Agents; Carrier State; Cross Infection; Disinfectants; Hand; Hexachlorophene; Humans;

1971

Trials

2 trials available for hexachlorophene and Infection, Postoperative Wound

ArticleYear
Postoperative chest wound infections in patients requiring coronary bypass. A controlled study evaluating prophylactic antibiotics.
    The Journal of thoracic and cardiovascular surgery, 1977, Volume: 73, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Asepsis; Coronary Artery Bypass; Female; Hexachlorophene; Humans; Male;

1977
Preoperative use of povidone-iodine. A prospective, randomized study.
    Clinical orthopaedics and related research, 1986, Issue:213

    Topics: Ambulatory Care; Clinical Trials as Topic; Hexachlorophene; Humans; Orthopedics; Povidone; Povidone-

1986

Other Studies

27 other studies available for hexachlorophene and Infection, Postoperative Wound

ArticleYear
NEW IODINE COMPOUND FOR DEGERMING SKIN SURFACE.
    Archives of surgery (Chicago, Ill. : 1960), 1963, Volume: 87

    Topics: Hexachlorophene; Humans; Iodine; Iodine Compounds; Skin; Sterilization; Surgical Procedures, Operati

1963
[THE APPLICATION OF RITOSEPT IN SURGICAL THERAPY].
    Magyar sebeszet, 1963, Volume: 16

    Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Hexachlorophene; Humans; Minor Surgical Procedu

1963
[PREOPERATIVE HAND DISINFECTION TODAY].
    Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1963, Nov-05, Volume: 304

    Topics: Anti-Infective Agents, Local; Halogens; Hand; Hand Disinfection; Hexachlorophene; Humans; Hydrocarbo

1963
INFECTION AND HEALING IN SUPERFICIAL WOUNDS. A COMPARATIVE CLINICAL STUDY OF TOPICAL TREATMENT METHODS.
    California medicine, 1964, Volume: 100

    Topics: Administration, Topical; Anti-Bacterial Agents; Bacitracin; Biomedical Research; Burns; Chlorampheni

1964
INADEQUACIES OF PRESENT METHODS OF SURGICAL SKIN PREPARATION.
    Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 89

    Topics: Alcohols; Anti-Bacterial Agents; Bacteriological Techniques; Bacteriology; Cross Infection; Gloves,

1964
POVIDONE-IODINE. EXTENSIVE SURGICAL EVALUATION OF A NEW ANTISEPTIC AGENT.
    American journal of surgery, 1964, Volume: 108

    Topics: Aerosols; Anti-Infective Agents; Anti-Infective Agents, Local; Biomedical Research; Burns; Hexachlor

1964
EFFECTIVE USE OF PROPHYLACTIC ANTIBIOTICS IN OPEN HEART SURGERY.
    Archives of surgery (Chicago, Ill. : 1960), 1965, Volume: 90

    Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Drug Therapy; Endocarditis; Endocarditis, Bacter

1965
ANTI-INFECTION MEASURES IN STAPES SURGERY.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1965, Volume: 81

    Topics: Anti-Bacterial Agents; Bacteriological Techniques; Drug Therapy; Ear Canal; Hexachlorophene; Humans;

1965
Variables in skin preparations may make comparison of antiseptics difficult.
    Journal of the American Veterinary Medical Association, 1999, Dec-01, Volume: 215, Issue:11

    Topics: 2-Propanol; Adhesives; Aerosols; Animals; Anti-Infective Agents, Local; Bacteria; Drug Interactions;

1999
Bacteriological comparison of hexachlorophene and polyvinylpyrrolidone-iodine surgical scrub soaps.
    The American surgeon, 1967, Volume: 33, Issue:11

    Topics: Anti-Infective Agents, Local; Bacteria; Equipment and Supplies, Hospital; Hexachlorophene; Humans; I

1967
Surgical antiseptics.
    Journal of the American Academy of Dermatology, 1983, Volume: 9, Issue:5

    Topics: Anti-Infective Agents, Local; Benzalkonium Compounds; Chlorhexidine; Drug Evaluation; Ethanol; Hand

1983
The antimicrobial effectiveness of operative-site preparative agents: a microbiological and clinical study.
    The Journal of bone and joint surgery. American volume, 1980, Volume: 62, Issue:5

    Topics: Anti-Infective Agents, Local; Bacteria; Disinfection; Hexachlorophene; Hip Joint; Humans; Iodine; Io

1980
[An agent imparting antimicrobial properties to woven materials].
    Klinicheskaia khirurgiia, 1994, Issue:6

    Topics: Bandages; Bedding and Linens; Disinfection; Hexachlorophene; Humans; Surgical Wound Infection

1994
Prophylaxis of neurosurgical infections by improved preoperative disinfection of the scalp.
    Scandinavian journal of infectious diseases, 1979, Volume: 11, Issue:2

    Topics: Administration, Topical; Antisepsis; Asepsis; Brain; Hexachlorophene; Humans; Preoperative Care; Sca

1979
[Antiseptic action of Remanex on the hand skin].
    Polski przeglad chirurgiczny, 1976, Volume: 48, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteria; Drug Combinations; Fungi; Hand; Hexachlorophene; Humans; Mer

1976
The use of phenanthroline metal chelates for the control of topical infections due to bacteria, fungi and protozoa.
    The Medical journal of Australia, 1970, Aug-15, Volume: 2, Issue:7

    Topics: Acne Vulgaris; Adult; Candida; Candidiasis; Cesarean Section; Chronic Disease; Copper; Emulsions; Fe

1970
[Trial of a hexachlorophene emulsion in preoperative skin preparation].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1965, Nov-08, Volume: 41, Issue:46

    Topics: Hexachlorophene; Humans; Preoperative Care; Surgical Wound Infection

1965
[Evaluation of the efficiency of Remanex in surgical disinfection of hands].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1974, Jul-01, Volume: 29, Issue:26

    Topics: Cross Infection; Detergents; Drug Evaluation; Hexachlorophene; Humans; Sterilization; Surgical Wound

1974
Silver allantoinate as an inhibitor of cutaneous bacteria upon the hands of operating room personnel.
    Annals of surgery, 1970, Volume: 171, Issue:6

    Topics: Allantoin; Anti-Infective Agents, Local; Antisepsis; Detergents; Escherichia coli Infections; Female

1970
Potentiation of wound infection by adhesive adjuncts.
    The American surgeon, 1972, Volume: 38, Issue:6

    Topics: 1-Propanol; Adhesiveness; Aerosols; Aloe; Animals; Balsams; Bandages; Camphor; Guinea Pigs; Hexachlo

1972
The comparative effectiveness of iodophor and hexachlorophene surgical scrub solutions.
    Surgery, gynecology & obstetrics, 1972, Volume: 135, Issue:6

    Topics: Anti-Infective Agents, Local; Bacteria; Gloves, Surgical; Hand; Hexachlorophene; Humans; Iodine; Mar

1972
[Experiences with the use of peracetic acid as disinfectant agent in surgery].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1971, Volume: 50, Issue:9

    Topics: Acetates; Bacteria; Disinfectants; Drug Synergism; Hexachlorophene; Humans; Peroxides; Solutions; Su

1971
Post-operative wound infection. Predisposing factors and the effect of a reduction in the dissemination of staphylococci.
    Acta medica Scandinavica. Supplementum, 1970, Volume: 514

    Topics: Adult; Age Factors; Analysis of Variance; Bacteriophage Typing; Bedding and Linens; Cross Infection;

1970
[An experimental study of antimicrobial tissues on a model of pathogenic staphylococci].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1967, Volume: 44, Issue:8

    Topics: Acetates; Anti-Infective Agents, Local; Bandages; Cellulose; Colistin; Copper; Drug Resistance, Micr

1967
[A study of the antimicrobial activity of viscose and acetate fibers containing hexachlorophene].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1967, Volume: 44, Issue:3

    Topics: Acetates; Bacteria; Bandages; Candida; Hexachlorophene; Polymers; Surgical Wound Infection

1967
Location of cutaneous microorganisms.
    Surgery, 1968, Volume: 64, Issue:6

    Topics: Biopsy; Hexachlorophene; Humans; Sebaceous Glands; Skin; Surgical Wound Infection; Sweat Glands

1968
[The effect of laundering and sterilization on the antimicrobial activity of dressings].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1968, Volume: 45, Issue:9

    Topics: Acetates; Anti-Bacterial Agents; Bandages; Copper; Hexachlorophene; Laundering; Silver; Sterilizatio

1968