Page last updated: 2024-10-28

hexachlorophene and Hemolysis

hexachlorophene has been researched along with Hemolysis in 5 studies

Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" The dose-response curves by HCP and PCP were sigmoidal, indicating cooperative inhibition, while those by 2,4,5-TCP and 2,4,6-TCP were not."1.30Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes. ( Igisu, H; Ikeda, M; Matsumura, H; Matsuoka, M, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumura, H1
Matsuoka, M1
Igisu, H1
Ikeda, M1
Miller, TL2
Gaughan, PL1
Buhler, DR3
Corner, TR1
Flores, G1

Other Studies

5 other studies available for hexachlorophene and Hemolysis

ArticleYear
Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes.
    Archives of toxicology, 1997, Volume: 71, Issue:3

    Topics: Adult; Chlorophenols; Cholinesterase Inhibitors; Erythrocyte Membrane; Erythrocytes; Hemolysis; Hexa

1997
Effects of halogenated antibacterials on the erythrocyte membrane.
    Chemico-biological interactions, 1978, Volume: 22, Issue:2-3

    Topics: Anti-Infective Agents; Chlorophenols; Erythrocyte Membrane; Hemolysis; Hexachlorophene; Humans; In V

1978
Hemolysis by hexachlorophene.
    Chemico-biological interactions, 1974, Volume: 8, Issue:2

    Topics: Dose-Response Relationship, Drug; Erythrocytes; Ethanol; Hemolysis; Hexachlorophene; Humans; Sodium

1974
Hemolytic properties of hexachlorophene and related chlorinated bisphenols.
    Biochemical pharmacology, 1974, Jul-01, Volume: 23, Issue:13

    Topics: Animals; Cell Nucleus; Erythrocytes; Hemolysis; Hexachlorophene; Humans; Hydrocarbons, Halogenated;

1974
Effect of hexachlorophene on monovalent cation transport in human erythrocytes. A mechanism for hexachlorophene-induced hemolysis.
    Biochimica et biophysica acta, 1974, May-30, Volume: 352, Issue:1

    Topics: Adult; Binding Sites; Carbon Radioisotopes; Cell Membrane; Computers; Erythrocytes; Hemolysis; Hexac

1974