hexachlorophene has been researched along with Hemolysis in 5 studies
Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
Excerpt | Relevance | Reference |
---|---|---|
" The dose-response curves by HCP and PCP were sigmoidal, indicating cooperative inhibition, while those by 2,4,5-TCP and 2,4,6-TCP were not." | 1.30 | Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes. ( Igisu, H; Ikeda, M; Matsumura, H; Matsuoka, M, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (80.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Matsumura, H | 1 |
Matsuoka, M | 1 |
Igisu, H | 1 |
Ikeda, M | 1 |
Miller, TL | 2 |
Gaughan, PL | 1 |
Buhler, DR | 3 |
Corner, TR | 1 |
Flores, G | 1 |
5 other studies available for hexachlorophene and Hemolysis
Article | Year |
---|---|
Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes.
Topics: Adult; Chlorophenols; Cholinesterase Inhibitors; Erythrocyte Membrane; Erythrocytes; Hemolysis; Hexa | 1997 |
Effects of halogenated antibacterials on the erythrocyte membrane.
Topics: Anti-Infective Agents; Chlorophenols; Erythrocyte Membrane; Hemolysis; Hexachlorophene; Humans; In V | 1978 |
Hemolysis by hexachlorophene.
Topics: Dose-Response Relationship, Drug; Erythrocytes; Ethanol; Hemolysis; Hexachlorophene; Humans; Sodium | 1974 |
Hemolytic properties of hexachlorophene and related chlorinated bisphenols.
Topics: Animals; Cell Nucleus; Erythrocytes; Hemolysis; Hexachlorophene; Humans; Hydrocarbons, Halogenated; | 1974 |
Effect of hexachlorophene on monovalent cation transport in human erythrocytes. A mechanism for hexachlorophene-induced hemolysis.
Topics: Adult; Binding Sites; Carbon Radioisotopes; Cell Membrane; Computers; Erythrocytes; Hemolysis; Hexac | 1974 |