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hexachlorophene and Edema

hexachlorophene has been researched along with Edema in 8 studies

Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
" This technique measures tissue distribution to the radioisotope, 14C-iodoantipyrine, and was used to compare NBF in sciatic nerves of rats with increased EFP induced by feeding them hexachlorophene (HCP), a neurotoxin which causes edema exclusively to the nervous system and confined to the myelin sheath."3.66Reduced nerve blood flow in hexachlorophene neuropathy: relationship to elevated endoneurial fluid pressure. ( Lampert, PW; Mizisin, AP; Myers, RR; Powell, HC, 1982)
"A technique for microgravimetric analysis of nerve edema was used to demonstrate increased water content in hexachlorophene neuropathy."3.66Microgravimetric analysis of nerve edema. ( Costello, ML; Myers, RR; Powell, HC, 1982)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Myers, RR3
Mizisin, AP1
Powell, HC3
Lampert, PW2
Costello, ML1
Hanig, JP1
Yoder, PD1
Krop, S1
Zweifach, BW1
Maxwell, IC1
Le Quesne, PM1
Curley, A1
Kimbrough, RD2
Hawk, RE1
Nathenson, G1
Finberg, L1
Towfighi, J1
Gonatas, NK1
McCree, L1

Other Studies

8 other studies available for hexachlorophene and Edema

ArticleYear
Reduced nerve blood flow in hexachlorophene neuropathy: relationship to elevated endoneurial fluid pressure.
    Journal of neuropathology and experimental neurology, 1982, Volume: 41, Issue:4

    Topics: Animals; Blood Pressure; Edema; Extracellular Space; Hexachlorophene; Peripheral Nervous System Dise

1982
Microgravimetric analysis of nerve edema.
    Muscle & nerve, 1982, Volume: 5, Issue:4

    Topics: Animals; Body Water; Densitometry; Desiccation; Edema; Female; Hexachlorophene; Peripheral Nervous S

1982
Protection with butylated hydroxytoluene and other compounds against intoxication and mortality caused by hexachlorophene.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:3

    Topics: Animals; Antidotes; Antioxidants; Brain Edema; Butylated Hydroxytoluene; Edema; Hexachlorophene; Int

1984
Endoneurial pressure in hexachlorophene neuropathy.
    Acta neuropathologica, 1978, Feb-20, Volume: 41, Issue:2

    Topics: Animals; Axons; Demyelinating Diseases; Edema; Hexachlorophene; Microcirculation; Nerve Degeneration

1978
Conduction velocity in hexachlorophane neuropathy: correlation between electrophysiological and histological findings.
    Journal of the neurological sciences, 1979, Volume: 43, Issue:1

    Topics: Action Potentials; Animals; Demyelinating Diseases; Edema; Hexachlorophene; Muscles; Myelin Sheath;

1979
Dermal absorption of hexochlorophane in infants.
    Lancet (London, England), 1971, Aug-07, Volume: 2, Issue:7719

    Topics: Administration, Oral; Animals; Brain; Chromatography, Gas; Edema; Female; Hexachlorophene; Humans; I

1971
The toxicity of polychlorinated polycyclic compounds and related chemicals.
    CRC critical reviews in toxicology, 1974, Volume: 2, Issue:4

    Topics: Anilides; Animals; Benzofurans; Carbanilides; Dermatitis, Contact; Dioxins; Edema; Food Contaminatio

1974
Hexachlorophene-induced changes in central and peripheral myelinated axons of developing and adult rats.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 31, Issue:6

    Topics: Age Factors; Animals; Animals, Newborn; Axons; Brain; Central Nervous System; Edema; Female; Gliosis

1974