hexachlorophene has been researched along with Disease Models, Animal in 9 studies
Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " When labeled rats were given demyelinating agents (triethyl tin chloride, hexachlorophene, sodium cyanide) and when experimental allergic encephalomyelitis was induced, a measurable increase in urinary 14C label above control levels was found." | 3.69 | Central nervous system demyelinating diseases and increased release of cholesterol into the urinary system of rats. ( Nicholas, HJ; Taylor, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Eleuteri, S | 1 |
| Di Giovanni, S | 1 |
| Rockenstein, E | 1 |
| Mante, M | 1 |
| Adame, A | 1 |
| Trejo, M | 1 |
| Wrasidlo, W | 1 |
| Wu, F | 1 |
| Fraering, PC | 1 |
| Masliah, E | 1 |
| Lashuel, HA | 1 |
| Nicholas, HJ | 1 |
| Taylor, J | 1 |
| Andreas, K | 1 |
| De Jesus, PV | 1 |
| Pleasure, DE | 1 |
| Webster, Hde F | 1 |
| Reier, PJ | 1 |
| Kies, MW | 1 |
| O'Connell, MF | 1 |
| Hayes, TJ | 1 |
| Bailer, J | 1 |
| Mitrovic, M | 1 |
| Ray, RJ | 1 |
| Dajani, AS | 1 |
| Hill, PL | 1 |
| Wannamaker, LW | 1 |
9 other studies available for hexachlorophene and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Bithionol; Cells, | 2015 |
Central nervous system demyelinating diseases and increased release of cholesterol into the urinary system of rats.
Topics: Animals; Carbon Radioisotopes; Central Nervous System Diseases; Cholesterol; Demyelinating Diseases; | 1994 |
Efficacy of cerebroprotective substances in the management of functional disorders induced by the cytotoxic brain oedema-producing substance hexachlorophene.
Topics: Animals; Behavior, Animal; Brain Edema; Calcium Channel Blockers; Disease Models, Animal; Hexachloro | 1993 |
Hexachlorophene neuropathy.
Topics: Animals; Centrifugation, Density Gradient; Demyelinating Diseases; Disease Models, Animal; Dose-Resp | 1973 |
A simple method for quantitative morphological studies of CNS demyelination: whole mounts of tadpole optic nerves examined by differential-interference microscopy.
Topics: Animals; Blood Transfusion; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoi | 1974 |
Murine fascioliasis: laboratory model for the detection of fasciolicidal activity of chemical compounds.
Topics: Anilides; Animals; Anthelmintics; Bromine; Catechols; Chlorine; Disease Models, Animal; Fascioliasis | 1973 |
Studies on the effect of various anthelmintics upon Fasciola hepatica in albino rats.
Topics: Age Factors; Animals; Anthelmintics; Carbon Tetrachloride; Disease Models, Animal; Fasciola hepatica | 1970 |
Experimental infection of the skin in the hamster simulating human impetigo. II. Assessment of various therapeutic regimens.
Topics: Animals; Anti-Infective Agents, Local; Bacitracin; Cricetinae; Debridement; Disease Models, Animal; | 1971 |