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hexachlorophene and Delayed Effects, Prenatal Exposure

hexachlorophene has been researched along with Delayed Effects, Prenatal Exposure in 5 studies

Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.

Research Excerpts

ExcerptRelevanceReference
"Hexachlorophene (HCP) has been shown to induce myelin vacuolation due to intramyelinic edema of the nerve fibers in animal neural tissue."1.43Maternal exposure to hexachlorophene targets intermediate-stage progenitor cells in the hippocampal neurogenesis involving myelin vacuolation of cholinergic and glutamatergic inputs in mice. ( Abe, H; Itahashi, M; Kato, M; Kikuchihara, Y; Kimura, M; Mizukami, S; Shibutani, M; Yoshida, T, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, Y1
Abe, H3
Nakajima, K1
Ideta-Otsuka, M1
Igarashi, K1
Woo, GH1
Yoshida, T3
Shibutani, M3
Itahashi, M2
Tanaka, T1
Mizukami, S2
Kimura, M2
Kato, M1
Kikuchihara, Y1
Rao, KS1
Schwetz, BA1
Wiggins, RC1

Reviews

2 reviews available for hexachlorophene and Delayed Effects, Prenatal Exposure

ArticleYear
Reproductive toxicity of environmental agents.
    Annual review of public health, 1982, Volume: 3

    Topics: Animals; Central Nervous System Agents; Central Nervous System Depressants; Coloring Agents; Environ

1982
Myelination: a critical stage in development.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Cell Division; Ethanol; Female; Fetal Alcohol Spectrum Disorders; F

1986

Other Studies

3 other studies available for hexachlorophene and Delayed Effects, Prenatal Exposure

ArticleYear
Aberrant Epigenetic Gene Regulation in GABAergic Interneuron Subpopulations in the Hippocampal Dentate Gyrus of Mouse Offspring Following Developmental Exposure to Hexachlorophene.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 05-01, Volume: 163, Issue:1

    Topics: Animals; Animals, Newborn; Dentate Gyrus; Epigenesis, Genetic; Female; GABAergic Neurons; gamma-Amin

2018
Maternal exposure to hexachlorophene targets intermediate-stage progenitor cells of the hippocampal neurogenesis in rat offspring via dysfunction of cholinergic inputs by myelin vacuolation.
    Toxicology, 2015, Feb-03, Volume: 328

    Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Cell Lineage; Cholinergic Fibers; Female; GABAerg

2015
Maternal exposure to hexachlorophene targets intermediate-stage progenitor cells in the hippocampal neurogenesis involving myelin vacuolation of cholinergic and glutamatergic inputs in mice.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:2

    Topics: Animals; Cholinergic Agents; Excitatory Amino Acid Agents; Female; Hexachlorophene; Hippocampus; Mal

2016