hexachlorophene has been researched along with Central Nervous System Diseases in 13 studies
Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| " When labeled rats were given demyelinating agents (triethyl tin chloride, hexachlorophene, sodium cyanide) and when experimental allergic encephalomyelitis was induced, a measurable increase in urinary 14C label above control levels was found." | 3.69 | Central nervous system demyelinating diseases and increased release of cholesterol into the urinary system of rats. ( Nicholas, HJ; Taylor, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin-Bouyer, G | 1 |
| Lebreton, R | 1 |
| Toga, M | 1 |
| Stolley, PD | 1 |
| Lockhart, J | 1 |
| Nicholas, HJ | 1 |
| Taylor, J | 1 |
| Le Quesne, PM | 1 |
| Bressler, R | 1 |
| Walson, PD | 1 |
| Fulginitti, VA | 1 |
| Plueckhahn, VD | 1 |
| Collins, RB | 1 |
| McCarl, GW | 1 |
| Hall, GA | 1 |
| Reid, IM | 1 |
| Kimbrough, RD | 1 |
| Körlof, B | 1 |
| Winsten, J | 1 |
| Ulsamer, AG | 1 |
| O'Connell, MF | 1 |
2 reviews available for hexachlorophene and Central Nervous System Diseases
| Article | Year |
|---|---|
Neurotoxic substances.
Topics: Acrylamides; Animals; Cats; Central Nervous System Diseases; Clioquinol; Environmental Exposure; Hex | 1975 |
Hexachlorophene in the newborn nursery. A risk-benefit analysis and review.
Topics: Animals; Baths; Central Nervous System Diseases; Disease Outbreaks; Hexachlorophene; Humans; Infant | 1977 |
11 other studies available for hexachlorophene and Central Nervous System Diseases
| Article | Year |
|---|---|
Outbreak of accidental hexachlorophene poisoning in France.
Topics: Accidents, Occupational; Brain Diseases; Central Nervous System Diseases; Child, Preschool; Disease | 1982 |
Central nervous system demyelinating diseases and increased release of cholesterol into the urinary system of rats.
Topics: Animals; Carbon Radioisotopes; Central Nervous System Diseases; Cholesterol; Demyelinating Diseases; | 1994 |
Hexachlorophene emulsions and antiseptic skin care of newborn infants.
Topics: Autopsy; Central Nervous System Diseases; Emulsions; Follow-Up Studies; Hexachlorophene; Humans; Inf | 1976 |
Letter: Comments and questions on the neurotoxicity of hexachlorophene.
Topics: Baths; Central Nervous System Diseases; Hexachlorophene; Humans; Infant, Newborn; Time Factors | 1975 |
Chemical safety. Preliminary results of a study carried out 16 years after hexachlorophene poisoning among young children.
Topics: Central Nervous System Diseases; Child; Female; Follow-Up Studies; Hexachlorophene; Humans; Learning | 1991 |
Hexachlorophane toxicity in sheep.
Topics: Animals; Central Nervous System; Central Nervous System Diseases; Dose-Response Relationship, Drug; | 1972 |
Review of recent evidence of toxic effects of hexachlorophene.
Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Blindness; Body Temperature; Brain Chemistry; | 1973 |
The complications of Phisohex.
Topics: Adolescent; Aged; Anti-Infective Agents, Local; Burns; Central Nervous System Diseases; Child; Chole | 1967 |
Hexachlorophene induced myelin lesions in the developing nervous system of Xenopus tadpoles: morphological and biochemical observations.
Topics: Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Cell Nucleus; Central Nervous System; Centra | 1974 |
American Academy of Pediatrics Committee on Fetus and Newborn: hexachlorophene and skin care of newborn infants.
Topics: Central Nervous System Diseases; Hexachlorophene; Humans; Hygiene; Infant, Newborn; Nurseries, Hospi | 1972 |
Hexachlorophene.
Topics: Animals; Australia; Central Nervous System; Central Nervous System Diseases; Hexachlorophene; Humans | 1972 |