hexachlorophene has been researched along with Brain Disorders in 25 studies
Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess neurotoxic effects of hexachlorophene in the human population previously shown to be most at risk, a blind clinicopathological analysis was made of all premature infants under 1,400 gm birth weight who survived at least four days and were examined by autopsy over a 7." | 3.65 | Neurotoxicity of hexachlorophene in humans. II. A clinicopathological study of 46 premature infants. ( Alvord, EC; Leech, RW; Shuman, RM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (96.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin-Bouyer, G | 1 |
| Lebreton, R | 1 |
| Toga, M | 1 |
| Stolley, PD | 1 |
| Lockhart, J | 1 |
| Rossiter, EJ | 1 |
| Anderson, JM | 2 |
| Cockburn, F | 1 |
| Forfar, JO | 1 |
| Harkness, RA | 2 |
| Kelly, RW | 2 |
| Kilshaw, B | 1 |
| Cooperman, EM | 1 |
| Gowdy, JM | 1 |
| Ulsamer, AG | 1 |
| Chilcote, R | 1 |
| Curley, A | 1 |
| Loughlin, HH | 1 |
| Jupin, JA | 1 |
| Shuman, RM | 3 |
| Leech, RW | 3 |
| Alvord, EC | 3 |
| Kilshaw, BH | 1 |
| Haley, RW | 1 |
| Takeuchi, T | 1 |
| Suzuki, M | 1 |
| Sitizyo, K | 1 |
| Isobe, R | 1 |
| Saito, T | 1 |
| Umemura, T | 1 |
| Shimada, A | 1 |
| Larrègue, M | 1 |
| Bressieux, JM | 1 |
| Laidet, B | 1 |
| Titi, A | 1 |
| Kimbrough, RD | 3 |
| Mettler, FA | 1 |
| Mullick, FG | 1 |
| Powell, H | 1 |
| Swarner, O | 1 |
| Gluck, L | 1 |
| Lampert, P | 1 |
| Gaines, TB | 1 |
| Linder, RE | 1 |
| Martinez, AJ | 1 |
| Boehm, R | 1 |
| Hadfield, MG | 1 |
| James, LS | 1 |
4 reviews available for hexachlorophene and Brain Disorders
| Article | Year |
|---|---|
Hexachlorophene in the nursery.
Topics: Asepsis; Brain Diseases; Cross Infection; Hexachlorophene; Humans; Infant Care; Infant, Newborn; Inf | 1977 |
Hexachlorophene lesions in newborn infants.
Topics: Abnormalities, Drug-Induced; Baths; Brain Diseases; Cosmetics; Female; Fetal Death; Hexachlorophene; | 1976 |
Hexachlorophene in the nursery.
Topics: Animals; Baths; Brain; Brain Diseases; Emulsions; Hexachlorophene; Humans; Infant, Newborn; Powders; | 1973 |
Review of the toxicity of hexachlorophene.
Topics: Adult; Animals; Brain Diseases; Brain Edema; Burns; Child; Hexachlorophene; Humans; Infant, Newborn; | 1971 |
21 other studies available for hexachlorophene and Brain Disorders
| Article | Year |
|---|---|
Hexachlorophene today.
Topics: Brain Diseases; Emulsions; Hexachlorophene; Humans; Infant, Newborn; Infant, Newborn, Diseases; Talc | 1982 |
Outbreak of accidental hexachlorophene poisoning in France.
Topics: Accidents, Occupational; Brain Diseases; Central Nervous System Diseases; Child, Preschool; Disease | 1982 |
Hexachlorophene--time to stop.
Topics: Australia; Brain Diseases; Cross Infection; Hexachlorophene; Humans; Infant, Newborn; Infant, Newbor | 1980 |
Neonatal spongioform myelinopathy after restricted application of hexachlorophane skin disinfectant.
Topics: Brain; Brain Chemistry; Brain Diseases; Female; Hexachlorophene; Humans; Infant, Low Birth Weight; I | 1981 |
Hexachlorophane--yes or no.
Topics: Animals; Brain Diseases; Hexachlorophene; Humans; Infant, Newborn; Skin Diseases, Infectious; Staphy | 1977 |
Hexachlorophene storage in a burn patient associated with encephalopathy.
Topics: Brain Diseases; Burns; Child; Hexachlorophene; Humans; Male | 1977 |
Neurotoxicity of topically applied hexachlorophene in the young rat.
Topics: Administration, Topical; Age Factors; Animals; Animals, Newborn; Brain; Brain Diseases; Brain Stem; | 1975 |
Neurotoxicity of hexachlorophene in humans. II. A clinicopathological study of 46 premature infants.
Topics: Administration, Topical; Birth Weight; Brain Diseases; Brain Edema; Brain Stem; Gastrointestinal Mot | 1975 |
Spongioform myelinopathy in premature infants.
Topics: Brain Chemistry; Brain Diseases; Hexachlorophene; Humans; Infant, Newborn; Infant, Premature, Diseas | 1975 |
Letter: Hexachlorophene toxicity in rats.
Topics: Animals; Brain Diseases; Hexachlorophene; Rats | 1976 |
Visual evoked potentials in guinea pigs with brain lesion.
Topics: Animals; Brain; Brain Diseases; Evoked Potentials, Visual; Guinea Pigs; Hexachlorophene; Male; Occip | 1992 |
Bovine spongiform encephalopathy.
Topics: Animals; Brain Diseases; Cattle; Cattle Diseases; Hexachlorophene | 1988 |
[Caustic diaper dermatitis and toxic encephalopathy following the application of talc contaminated by hexachlorophene].
Topics: Brain Diseases; Diaper Rash; Hexachlorophene; Humans; Infant; Powders; Talc | 1986 |
Review of recent evidence of toxic effects of hexachlorophene.
Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Blindness; Body Temperature; Brain Chemistry; | 1973 |
Neurotoxicity of hexachlorophene in the human: I. A clinicopathologic study of 248 children.
Topics: Antisepsis; Autopsy; Baths; Birth Weight; Brain Diseases; Child, Preschool; Gestational Age; Hexachl | 1974 |
Burn encephalopathy or hexachlorophene poisoning?
Topics: Brain Diseases; Burns; Diagnosis, Differential; Hexachlorophene; Humans; Poisoning | 1973 |
Hexachlorophene toxicity. Human experience at the Armed Forces Institute of Pathology.
Topics: Administration, Oral; Adult; Age Factors; Autopsy; Baths; Brain; Brain Diseases; Burns; Child, Presc | 1973 |
Hexachlorophene myelinopathy in premature infants.
Topics: Autopsy; Baths; Birth Weight; Brain Diseases; Brain Stem; Female; Gestational Age; Hexachlorophene; | 1973 |
The oral and dermal toxicity of hexachlorophene in rats.
Topics: Administration, Oral; Animals; Body Weight; Brain; Brain Diseases; Heart; Hematocrit; Hexachlorophen | 1973 |
Acute hexachlorophene encephalopathy: clinico-neuropathological correlation.
Topics: Acute Disease; Arrhythmias, Cardiac; Autopsy; Blindness; Brain Diseases; Brain Edema; Child; Diarrhe | 1974 |
Hexachlorophene.
Topics: Animals; Animals, Newborn; Brain Diseases; Hexachlorophene; Humans; Infant, Newborn; Infant, Newborn | 1972 |