hexachlorophene has been researched along with Abnormalities, Drug-Induced in 24 studies
Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
hexachlorophene : An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retrospective studies, performed in 6 hospitals in Sweden, demonstrated that severe congenital malformations occurred more frequently in neonates born to mothers who used hexachlorophene soaps, 10--60 times a day by handwashing and hand-creams during at least the first trimester of pregnancy (25 severe malformations in 460 neonates), when compared to neonates born to similarly employed mothers who did not use hexachlorophene soaps (0 severe malformations in 233 neonates)." | 3.66 | Suspected link between exposure to hexachlorophene and malformed infants. ( Halling, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, LM | 1 |
| Kleinberg, F | 1 |
| Rapoport, KA | 1 |
| Men'shikova, TA | 1 |
| Bobkova, EA | 1 |
| Lavery, JP | 1 |
| Mennuti, MT | 1 |
| Fischer, W | 1 |
| Halling, H | 2 |
| Baltzar, B | 2 |
| Ericson, A | 2 |
| Källén, B | 4 |
| Check, W | 1 |
| Janerich, DT | 1 |
| Gowdy, JM | 1 |
| Ulsamer, AG | 1 |
| Hemminki, K | 1 |
| Vineis, P | 1 |
| Kimmel, CA | 2 |
| Moore, W | 2 |
| Stara, JF | 2 |
| Gaya, H | 1 |
| Monti, A | 1 |
| Fishbein, L | 1 |
| Flamm, WG | 1 |
| Plueckhahn, VD | 1 |
| Hysell, DK | 1 |
5 reviews available for hexachlorophene and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Effects of drugs and chemicals on the fetus and newborn (2).
Topics: Abnormalities, Drug-Induced; Anticoagulants; Anticonvulsants; Diazepam; Drug-Related Side Effects an | 1984 |
Hexachlorophene lesions in newborn infants.
Topics: Abnormalities, Drug-Induced; Baths; Brain Diseases; Cosmetics; Female; Fetal Death; Hexachlorophene; | 1976 |
Extrapolation of the evidence on teratogenicity of chemicals between humans and experimental animals: chemicals other than drugs.
Topics: Abnormalities, Drug-Induced; Anesthetics; Animals; Caffeine; Cannabinoids; Carbon Monoxide; Copper; | 1985 |
Potential environmental chemical hazards. I. Drugs.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Rela | 1972 |
Hexachlorophane and skin care of newborn infants.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Burns; Carbon Isotopes; Child; Clinical Trials a | 1973 |
1 trial available for hexachlorophene and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Hexachlorophane and skin care of newborn infants.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Burns; Carbon Isotopes; Child; Clinical Trials a | 1973 |
19 other studies available for hexachlorophene and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Experimental data on the study of the embryotoxic action of hexachlorophene, a component of antimicrobial textiles and household chemicals].
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hexachl | 1982 |
Teratology for the dermatologist.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; | 1981 |
Drug and chemical risks to the fetus: occupational hazards for medical personnel.
Topics: Abnormalities, Drug-Induced; Anesthetics; Female; Health Occupations; Hexachlorophene; Humans; Infan | 1980 |
Birth defects linked to hexachlorophene.
Topics: Abnormalities, Drug-Induced; Female; Hexachlorophene; Humans; Infant, Newborn; Nursing Staff, Hospit | 1978 |
Hexachlorophene-birth defect link debated.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Cross Infection; Female; Hexachlorophene; Hum | 1978 |
Can hexachlorophene soap cause birth defects?
Topics: Abnormalities, Drug-Induced; Female; Hexachlorophene; Humans; Personnel, Hospital; Pregnancy; Sweden | 1978 |
[Malformations caused by hexachlorophen].
Topics: Abnormalities, Drug-Induced; Hexachlorophene; Humans; Infant Care; Infant, Newborn | 1978 |
Suspected link between exposure to hexachlorophene and malformed infants.
Topics: Abnormalities, Drug-Induced; Animals; Environmental Exposure; Female; Fetal Diseases; Hexachlorophen | 1979 |
Delivery outcome in women employed in medical occupations in Sweden.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Environmental Exposure; Female; Health Occupations; | 1979 |
New study shows hexachlorophene is teratogenic in humans.
Topics: Abnormalities, Drug-Induced; Administration, Topical; Female; Hexachlorophene; Humans; Infant, Newbo | 1978 |
Hexachlorophene teratogenicity in human disputed.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Female; Fetus; Hexachlorophene; Humans; Mater | 1978 |
[Delivery turnout among employees in medical care].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Environmental Exposure; Female; Hexachlorophene; | 1978 |
Environmental causes of birth defects: the hexachlorophene issue.
Topics: Abnormalities, Drug-Induced; Administration, Topical; Female; Hexachlorophene; Humans; Infant, Newbo | 1979 |
Pregnancy outcome among women working in Swedish hospitals.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Female; Fetal Death; Hexachlorophene; Humans; | 1979 |
[Suspected connection between exposure to hexachlorophene and birth of malformed infants].
Topics: Abnormalities, Drug-Induced; Administration, Topical; Allied Health Personnel; Drug Evaluation; Envi | 1977 |
Hexachlorophane teratogenicity in rats.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Gestational Age; Hexachlorophene; H | 1972 |
Hexachlorophane teratogenicity in rats.
Topics: Abnormalities, Drug-Induced; Animals; Drug Interactions; Female; Hexachlorophene; Maternal-Fetal Exc | 1972 |
[Chemical intoxication of the fetus and infant].
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Female; Fetal Diseases; Fishes; Food Contam | 1974 |
Teratogenicity of hexachlorophene in rats. Comparison of uptake following various routes of administration.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Brain; Carbon Radioisotopes; Dose-Respon | 1974 |