Page last updated: 2024-10-18

hexachlorocyclohexane and Pregnancy

hexachlorocyclohexane has been researched along with Pregnancy in 33 studies

Lindane: An organochlorine insecticide made up of greater than 99% gamma-Hexachlorocyclohexane. It has been used as a pediculicide and scabicide, and shown to cause cancer.
beta-hexachlorocyclohexane : The beta-isomer of hexachlorocyclohexane.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"β-Hexachlorocyclohexane (β-HCH) was the only chemical associated with ASD, after adjusting for 26 other chemicals."1.91Perinatal exposure to potential endocrine disrupting chemicals and autism spectrum disorder: From Norwegian birth cohort to zebrafish studies. ( Berg, V; Desalegn, AA; Eggesbø, M; Esguerra, CV; Iszatt, N; Kirstein-Smardzewska, KJ; Lenters, V; Lyche, JL; Stigum, H; van der Ent, W, 2023)
" A dose-response relationship was observed between PAH levels and the risk of NTDs, with odds ratios for the second, third, and fourth quartiles, compared with the first, of 1."1.37Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. ( Finnell, RH; Jin, L; Li, Z; Ma, J; Qiu, X; Ren, A; Zhang, L; Zhu, H; Zhu, T, 2011)
"102 cases of aneuploidy were disclosed."1.37The impact of first trimester screening and early fetal anomaly scan on invasive testing rates in women with advanced maternal age. ( Albig, M; Becker, R; Entezami, M; Gasiorek-Wiens, A; Hagen, A; Knoll, U; Stumm, M; Wegner, RD, 2011)
"23 cases each of preterm labor and full term labor were included in the study."1.35Maternal and cord blood levels of organochlorine pesticides: association with preterm labor. ( Ahmed, RS; Banerjee, BD; Guleria, K; Makhijani, SD; Pathak, R; Sharma, CS; Tripathi, AK, 2009)
"Upon review of the primary testicular tumor, small foci of intermediate trophoblastic tumor cells were discerned."1.32Placental site trophoblastic tumor in a late recurrence of a nonseminomatous germ cell tumor of the testis. ( Gietema, JA; Hoekstra, HJ; Suurmeijer, AJ, 2004)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.03)18.2507
2000's6 (18.18)29.6817
2010's21 (63.64)24.3611
2020's5 (15.15)2.80

Authors

AuthorsStudies
Želježić, D1
Herceg Romanić, S1
Klinčić, D1
Matek Sarić, M1
Letinić, JG1
Fang, J1
Liu, H1
Zhao, H1
Zhou, Y1
Xu, S1
Cai, Z1
Tyagi, V1
Garg, N1
Mustafa, MD1
Banerjee, BD3
Guleria, K3
Pathak, R2
Ahmed, RS2
Tripathi, AK1
Sharma, CS1
Makhijani, SD1
Ren, A1
Qiu, X1
Jin, L1
Ma, J1
Li, Z1
Zhang, L1
Zhu, H1
Finnell, RH1
Zhu, T1
Rudge, CVC1
Sandanger, T1
Röllin, HB2
Calderon, IMP1
Volpato, G1
Silva, JLP1
Duarte, G1
Neto, CM1
Sass, N1
Nakamura, MU1
Odland, JØ3
Rudge, MVC1
Sharma, E1
Mustafa, M1
Vaid, NB1
Channa, KR1
Wilson, KS1
Nøst, TH1
Naik, I1
Sandanger, TM1
Salcedo-Bellido, I1
Amaya, E1
Pérez-Díaz, C1
Soler, A1
Vela-Soria, F1
Requena, P1
Barrios-Rodríguez, R1
Echeverría, R1
Pérez-Carrascosa, FM1
Quesada-Jiménez, R1
Martín-Olmedo, P1
Arrebola, JP1
Rouxel, E1
Costet, N1
Monfort, C1
Audouze, K1
Cirugeda, L1
Gaudreau, E1
Grimalt, JO5
Ibarluzea, J2
Lainé, F1
Llop, S1
Lopez-Espinosa, MJ2
Rouget, F1
Santa-Marina, L1
Vrijheid, M2
Chevrier, C1
Casas, M2
Warembourg, C1
Desalegn, AA1
van der Ent, W1
Lenters, V1
Iszatt, N1
Stigum, H1
Lyche, JL1
Berg, V1
Kirstein-Smardzewska, KJ1
Esguerra, CV1
Eggesbø, M1
Kokroko, J1
Kogut, K1
Harley, K1
Eskenazi, B1
Wang, S1
Hu, C1
Lu, A1
Wang, Y1
Cao, L1
Wu, W1
Li, H1
Wu, M1
Yan, C1
Bjerregaard-Olesen, C1
Long, M1
Ghisari, M1
Bech, BH1
Nohr, EA1
Uldbjerg, N1
Henriksen, TB1
Olsen, J1
Bonefeld-Jørgensen, EC1
Zhang, X2
Wu, X1
Lei, B1
Jing, Y1
Jiang, Z1
Fang, X1
Yu, Y1
Bravo, N1
Chashchin, M1
Chashchin, VP1
Aerts, R1
Van Overmeire, I1
Colles, A1
Andjelković, M1
Malarvannan, G1
Poma, G1
Den Hond, E1
Van de Mieroop, E1
Dewolf, MC1
Charlet, F1
Van Nieuwenhuyse, A1
Van Loco, J1
Covaci, A1
Morales, E1
Gascon, M1
Martinez, D1
Ballester, F2
Rodríguez-Bernal, CL1
Marina, LS1
Espada, M1
Goñi, F2
Vizcaino, E2
Sunyer, J3
Patayová, H1
Wimmerová, S1
Lancz, K1
Palkovičová, L1
Drobná, B1
Fabišiková, A1
Kováč, J1
Hertz-Picciotto, I1
Jusko, TA1
Trnovec, T1
Curren, MS1
Davis, K1
Liang, CL1
Adlard, B1
Foster, WG1
Donaldson, SG1
Kandola, K1
Brewster, J1
Potyrala, M1
Van Oostdam, J1
Braun, JM1
Kalkbrenner, AE1
Just, AC1
Yolton, K1
Calafat, AM1
Sjödin, A1
Hauser, R1
Webster, GM1
Chen, A1
Lanphear, BP1
De la Cruz, R1
Fuentes, C1
Meza, C1
Lee, DJ1
Arribas-Gil, A1
Murcia, M1
Fuentes, V1
Garcia, AM1
Rebagliato, M1
Unsal, N1
Ozat, M1
Kanat-Pektas, M1
Gungor, T1
Danisman, N1
Garcia-Esteban, R2
Alvarez, M1
Guxens, M1
Basterrechea, M1
Guerra, S1
Antó, JM1
Hagen, A1
Entezami, M1
Gasiorek-Wiens, A1
Albig, M1
Becker, R1
Knoll, U1
Stumm, M1
Wegner, RD1
Yu, DY1
Wang, F1
Liu, Q1
Jiang, N1
Zhao, W1
Ren, HY1
Han, MY1
Zhang, K1
Li, S1
Ouyang, QQ1
Nie, Q1
Ahmed, AA1
Tom, BD1
Calabrese, P1
Suurmeijer, AJ1
Gietema, JA1
Hoekstra, HJ1
Pierik, FH1
Klebanoff, MA1
Brock, JW1
Longnecker, MP1
Alvarez-Pedrerol, M1
Ribas-Fitó, N1
Torrent, M1
Carrizo, D1
Gerhard, I1
Daniel, V1
Link, S1
Monga, B1
Runnebaum, B1
Karmaus, W1
DeKoning, EP1
Kruse, H1
Witten, J1
Osius, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neurobehavioral Effects of Prevalent Neurotoxicants in Children: A Cohort Study of the Cincinnati Center for Children's Environmental Health[NCT00129324]468 participants (Actual)Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

33 other studies available for hexachlorocyclohexane and Pregnancy

ArticleYear
Persistent Organochlorine Pollutants in Placentas Sampled from Women in Croatia and an Evaluation of Their DNA Damaging Potential In Vitro.
    Archives of environmental contamination and toxicology, 2018, Volume: 74, Issue:2

    Topics: Adult; Comet Assay; Croatia; DDT; Dichlorodiphenyl Dichloroethylene; DNA Damage; Environmental Expos

2018
Association of in utero hexachlorocyclohexane exposure with gestational age.
    Ecotoxicology and environmental safety, 2019, Jun-15, Volume: 174

    Topics: Adult; China; Endocrine Disruptors; Female; Fetal Blood; Gestational Age; Gestational Weight Gain; H

2019
Organochlorine pesticide levels in maternal blood and placental tissue with reference to preterm birth: a recent trend in North Indian population.
    Environmental monitoring and assessment, 2015, Volume: 187, Issue:7

    Topics: Adult; Birth Weight; Chromatography, Gas; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Moni

2015
Maternal and cord blood levels of organochlorine pesticides: association with preterm labor.
    Clinical biochemistry, 2009, Volume: 42, Issue:7-8

    Topics: DDT; Dichlorodiphenyl Dichloroethylene; Female; Fetal Blood; Hexachlorocyclohexane; Humans; Hydrocar

2009
Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-02, Volume: 108, Issue:31

    Topics: Case-Control Studies; China; DDT; Endosulfan; Environmental Monitoring; Environmental Pollutants; Ep

2011
Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil.
    Environment international, 2012, Volume: 40

    Topics: Adolescent; Adult; Brazil; Chlordan; Delivery, Obstetric; Dichlorodiphenyl Dichloroethylene; Environ

2012
A case control study of gene environmental interaction in fetal growth restriction with special reference to organochlorine pesticides.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 161, Issue:2

    Topics: Adult; Alleles; Birth Weight; Case-Control Studies; DDT; Dichlorodiphenyl Dichloroethylene; Endosulf

2012
Regional variation in pesticide concentrations in plasma of delivering women residing in rural Indian Ocean coastal regions of South Africa.
    Journal of environmental monitoring : JEM, 2012, Volume: 14, Issue:11

    Topics: Adolescent; Adult; DDT; Endosulfan; Environmental Exposure; Environmental Pollutants; Female; Hexach

2012
Differential Bioaccumulation Patterns of α, β-Hexachlorobenzene and Dicofol in Adipose Tissue from the GraMo Cohort (Southern Spain).
    International journal of environmental research and public health, 2022, 03-11, Volume: 19, Issue:6

    Topics: Adipose Tissue; Animals; Bioaccumulation; Dicofol; Female; Hexachlorocyclohexane; Humans; Hydrocarbo

2022
Prenatal exposure to multiple persistent organic pollutants in association with adiposity markers and blood pressure in preadolescents.
    Environment international, 2023, Volume: 178

    Topics: Adiposity; Adolescent; Bayes Theorem; Blood Pressure; Dichlorodiphenyl Dichloroethylene; Environment

2023
Perinatal exposure to potential endocrine disrupting chemicals and autism spectrum disorder: From Norwegian birth cohort to zebrafish studies.
    Environment international, 2023, Volume: 181

    Topics: Animals; Autism Spectrum Disorder; Birth Cohort; Endocrine Disruptors; Environmental Pollutants; Fem

2023
Prenatal β-Hexachlorocyclohexane (β-HCH) Exposure and 7-Year Child IQ in the CHAMACOS Birth Cohort.
    Neurotoxicity research, 2020, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Child; Cohort Studies; Female; Hexachlorocyclohexane; Humans; Insecticides; Intel

2020
Association between prenatal exposure to persistent organic pollutants and neurodevelopment in early life: A mother-child cohort (Shanghai, China).
    Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208

    Topics: Child Development; Child, Preschool; China; Cohort Studies; DDT; Dichlorodiphenyl Dichloroethylene;

2021
Temporal trends of lipophilic persistent organic pollutants in serum from Danish nulliparous pregnant women 2011-2013.
    Environmental science and pollution research international, 2017, Volume: 24, Issue:20

    Topics: Adult; Denmark; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female; Gestational Age

2017
Transplacental transfer characteristics of organochlorine pesticides in paired maternal and cord sera, and placentas and possible influencing factors.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 233

    Topics: Adult; China; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Monitoring; Environmental Pollut

2018
Drivers of maternal accumulation of organohalogen pollutants in Arctic areas (Chukotka, Russia) and 4,4'-DDT effects on the newborns.
    Environment international, 2019, Volume: 124

    Topics: Adult; Age Factors; Anthropometry; Arctic Regions; DDT; Environmental Pollutants; Female; Fetal Deve

2019
Determinants of persistent organic pollutant (POP) concentrations in human breast milk of a cross-sectional sample of primiparous mothers in Belgium.
    Environment international, 2019, Volume: 131

    Topics: Adult; Belgium; Child; Cross-Sectional Studies; Diet; Environmental Pollutants; Female; Flame Retard

2019
Associations between blood persistent organic pollutants and 25-hydroxyvitamin D3 in pregnancy.
    Environment international, 2013, Volume: 57-58

    Topics: Adult; Calcifediol; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female; Hexachlorob

2013
Anthropometric, socioeconomic, and maternal health determinants of placental transfer of organochlorine compounds.
    Environmental science and pollution research international, 2013, Volume: 20, Issue:12

    Topics: Adult; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female; Fetal Blood; Hexach

2013
Comparing plasma concentrations of persistent organic pollutants and metals in primiparous women from northern and southern Canada.
    The Science of the total environment, 2014, May-01, Volume: 479-480

    Topics: Adult; Canada; Dichlorodiphenyl Dichloroethylene; Environmental Monitoring; Environmental Pollutants

2014
Gestational exposure to endocrine-disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4- and 5-year-old children: the HOME study.
    Environmental health perspectives, 2014, Volume: 122, Issue:5

    Topics: Child Behavior; Child, Preschool; Endocrine Disruptors; Environmental Pollutants; Female; Flame Reta

2014
Predicting pregnancy outcomes using longitudinal information: a penalized splines mixed-effects model approach.
    Statistics in medicine, 2017, 06-15, Volume: 36, Issue:13

    Topics: Data Interpretation, Statistical; Female; Hexachlorocyclohexane; Humans; Longitudinal Studies; Model

2017
Prenatal exposure to organochlorine compounds and neonatal thyroid stimulating hormone levels.
    Journal of exposure science & environmental epidemiology, 2010, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Cohort Studies; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; F

2010
The significance of fetal maxillary length in the first trimester screening for trisomy 21.
    Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:6

    Topics: Adult; Cephalometry; Crown-Rump Length; Developing Countries; Down Syndrome; Female; Gestational Age

2011
DDE in mothers' blood during pregnancy and lower respiratory tract infections in their infants.
    Epidemiology (Cambridge, Mass.), 2010, Volume: 21, Issue:5

    Topics: Bronchiolitis; Bronchitis; Cohort Studies; Dichlorodiphenyl Dichloroethylene; Female; Hexachlorobenz

2010
The impact of first trimester screening and early fetal anomaly scan on invasive testing rates in women with advanced maternal age.
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2011, Volume: 32, Issue:3

    Topics: Adult; Algorithms; Amniocentesis; Aneuploidy; Chorionic Villi Sampling; Chromosome Disorders; Chromo

2011
[Establishment and application of median serum markers for second trimester screening in Qingdao region].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2012, Volume: 29, Issue:5

    Topics: Adult; alpha-Fetoproteins; Biomarkers; Estriol; Female; Hexachlorocyclohexane; Humans; Pregnancy; Pr

2012
Ectopic pregnancy diagnosis and the pseudo-sac.
    Fertility and sterility, 2004, Volume: 81, Issue:5

    Topics: False Positive Reactions; Female; Hexachlorocyclohexane; Humans; Logistic Models; Pregnancy; Pregnan

2004
Placental site trophoblastic tumor in a late recurrence of a nonseminomatous germ cell tumor of the testis.
    The American journal of surgical pathology, 2004, Volume: 28, Issue:6

    Topics: Adult; Female; Germinoma; Hexachlorocyclohexane; Humans; Male; Pregnancy; Recurrence; Testicular Neo

2004
Maternal pregnancy serum level of heptachlor epoxide, hexachlorobenzene, and beta-hexachlorocyclohexane and risk of cryptorchidism in offspring.
    Environmental research, 2007, Volume: 105, Issue:3

    Topics: Adult; Case-Control Studies; Cohort Studies; Cryptorchidism; Environmental Exposure; Female; Fungici

2007
Thyroid disruption at birth due to prenatal exposure to beta-hexachlorocyclohexane.
    Environment international, 2008, Volume: 34, Issue:6

    Topics: Cohort Studies; Female; Hexachlorocyclohexane; Humans; Infant, Newborn; Polychlorinated Biphenyls; P

2008
Chlorinated hydrocarbons in women with repeated miscarriages.
    Environmental health perspectives, 1998, Volume: 106, Issue:10

    Topics: Abortion, Habitual; Adult; Female; Germany; Hexachlorocyclohexane; Humans; Hydrocarbons, Chlorinated

1998
Early childhood determinants of organochlorine concentrations in school-aged children.
    Pediatric research, 2001, Volume: 50, Issue:3

    Topics: Birth Order; Breast Feeding; Child; Dichlorodiphenyldichloroethane; Dose-Response Relationship, Drug

2001