Page last updated: 2024-10-18

hexachlorocyclohexane and Parkinson Disease

hexachlorocyclohexane has been researched along with Parkinson Disease in 3 studies

Lindane: An organochlorine insecticide made up of greater than 99% gamma-Hexachlorocyclohexane. It has been used as a pediculicide and scabicide, and shown to cause cancer.
beta-hexachlorocyclohexane : The beta-isomer of hexachlorocyclohexane.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
" Serum levels of dieldrin were associated with depression and cognitive function in PD patients."4.12Analysis of serum levels of organochlorine pesticides and related factors in Parkinson's disease. ( Luo, Q; Qian, Y; Song, Y; Xiao, Q; Xu, S; Yang, X, 2022)
"beta-Hexachlorocyclohexane (beta-HCH) was more often detectable in patients with PD (76%) compared with controls (40%) and patients with Alzheimer disease (30%)."3.75Elevated serum pesticide levels and risk of Parkinson disease. ( Buckley, B; Diaz-Arrastia, R; German, DC; O'Suilleabhain, P; Reisch, J; Richardson, JR; Shalat, SL; Winnik, B, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Xu, S1
Yang, X1
Qian, Y1
Luo, Q1
Song, Y1
Xiao, Q1
Richardson, JR2
Shalat, SL2
Buckley, B2
Winnik, B2
O'Suilleabhain, P2
Diaz-Arrastia, R1
Reisch, J1
German, DC2
Roy, A1
Gearing, M1
Levey, AI1
Factor, SA1

Other Studies

3 other studies available for hexachlorocyclohexane and Parkinson Disease

ArticleYear
Analysis of serum levels of organochlorine pesticides and related factors in Parkinson's disease.
    Neurotoxicology, 2022, Volume: 88

    Topics: Aged; Blotting, Western; Case-Control Studies; Cell Line, Tumor; Cognition; Cognition Disorders; Dep

2022
Elevated serum pesticide levels and risk of Parkinson disease.
    Archives of neurology, 2009, Volume: 66, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Chi-Square Distribution; Female; H

2009
β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease.
    Neurotoxicology, 2011, Volume: 32, Issue:5

    Topics: Aged; Biomarkers; Case-Control Studies; Environmental Exposure; Female; Follow-Up Studies; Hexachlor

2011