Page last updated: 2024-10-18

hexachlorocyclohexane and Down Syndrome

hexachlorocyclohexane has been researched along with Down Syndrome in 2 studies

Lindane: An organochlorine insecticide made up of greater than 99% gamma-Hexachlorocyclohexane. It has been used as a pediculicide and scabicide, and shown to cause cancer.
beta-hexachlorocyclohexane : The beta-isomer of hexachlorocyclohexane.

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research Excerpts

ExcerptRelevanceReference
"102 cases of aneuploidy were disclosed."1.37The impact of first trimester screening and early fetal anomaly scan on invasive testing rates in women with advanced maternal age. ( Albig, M; Becker, R; Entezami, M; Gasiorek-Wiens, A; Hagen, A; Knoll, U; Stumm, M; Wegner, RD, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Unsal, N1
Ozat, M1
Kanat-Pektas, M1
Gungor, T1
Danisman, N1
Hagen, A1
Entezami, M1
Gasiorek-Wiens, A1
Albig, M1
Becker, R1
Knoll, U1
Stumm, M1
Wegner, RD1

Other Studies

2 other studies available for hexachlorocyclohexane and Down Syndrome

ArticleYear
The significance of fetal maxillary length in the first trimester screening for trisomy 21.
    Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:6

    Topics: Adult; Cephalometry; Crown-Rump Length; Developing Countries; Down Syndrome; Female; Gestational Age

2011
The impact of first trimester screening and early fetal anomaly scan on invasive testing rates in women with advanced maternal age.
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2011, Volume: 32, Issue:3

    Topics: Adult; Algorithms; Amniocentesis; Aneuploidy; Chorionic Villi Sampling; Chromosome Disorders; Chromo

2011