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hexachlorocyclohexane and Breast Cancer

hexachlorocyclohexane has been researched along with Breast Cancer in 12 studies

Lindane: An organochlorine insecticide made up of greater than 99% gamma-Hexachlorocyclohexane. It has been used as a pediculicide and scabicide, and shown to cause cancer.
beta-hexachlorocyclohexane : The beta-isomer of hexachlorocyclohexane.

Research Excerpts

ExcerptRelevanceReference
"Information on the association between exposure to beta-hexachlorocyclohexane (beta-HCH), hexachlorobenzene (HCB) or polychlorinated biphenyls (PCBs) and the incidence of breast cancer is inconclusive."7.71Serum levels of beta-hexachlorocyclohexane, hexachlorobenzene and polychlorinated biphenyls and breast cancer in Mexican women. ( Blair, A; Cebrián, ME; García, RM; López-Carrillo, L; López-Cervantes, M; Torres-Sánchez, L, 2002)
"It has been suggested that there is a positive correlation between increased incidence of breast cancer and the presence of organochlorine residues such as DDT and HCH in breast tissues in the United States."7.70Activation of c-Neu tyrosine kinase by o,p'-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells. ( Enan, E; Matsumura, F, 1998)
" The present study focuses attention on the mechanisms through which another organochlorine compound, beta-hexachlorocyclohexane (beta-HCH), exerts estrogen-like effects in human breast cancer cells."7.69Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells. ( Ben-Jonathan, N; Bigsby, RM; Caperell-Grant, A; Gize, EA; Madhukar, BV; Steinmetz, R; Young, PC, 1996)
"Information on the association between exposure to beta-hexachlorocyclohexane (beta-HCH), hexachlorobenzene (HCB) or polychlorinated biphenyls (PCBs) and the incidence of breast cancer is inconclusive."3.71Serum levels of beta-hexachlorocyclohexane, hexachlorobenzene and polychlorinated biphenyls and breast cancer in Mexican women. ( Blair, A; Cebrián, ME; García, RM; López-Carrillo, L; López-Cervantes, M; Torres-Sánchez, L, 2002)
"It has been suggested that there is a positive correlation between increased incidence of breast cancer and the presence of organochlorine residues such as DDT and HCH in breast tissues in the United States."3.70Activation of c-Neu tyrosine kinase by o,p'-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells. ( Enan, E; Matsumura, F, 1998)
" The present study focuses attention on the mechanisms through which another organochlorine compound, beta-hexachlorocyclohexane (beta-HCH), exerts estrogen-like effects in human breast cancer cells."3.69Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells. ( Ben-Jonathan, N; Bigsby, RM; Caperell-Grant, A; Gize, EA; Madhukar, BV; Steinmetz, R; Young, PC, 1996)
"Patients with breast cancer suffered significantly higher accumulation levels of 4,4-DDE compared with control subjects (P = 0."1.51Serum levels of Organochlorine Pesticides and Breast Cancer Risk in Iranian Women. ( Abolhassani, M; Akbari, H; Asadikaram, G; Fallah, H; Heidari, MR; Khazaeli, P; Moazed, V; Paydar, P; Zeynali Nejad, H, 2019)
"In addition, we analyzed the risk of breast cancer in those patients with organochlorine pesticides contamination using a logistic regression model."1.46Organochlorine pesticides accumulation and breast cancer: A hospital-based case-control study. ( He, TT; Wang, JG; Zhao, P; Zuo, AJ, 2017)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paydar, P1
Asadikaram, G1
Fallah, H1
Zeynali Nejad, H1
Akbari, H1
Abolhassani, M1
Moazed, V1
Khazaeli, P1
Heidari, MR1
He, TT1
Zuo, AJ1
Wang, JG1
Zhao, P1
Yang, JZ1
Wang, ZX1
Ma, LH1
Shen, XB1
Sun, Y1
Hu, DW1
Sun, LX1
Wong, PS1
Li, W1
Vogel, CF1
Matsumura, F3
Xu, X1
Dailey, AB1
Talbott, EO1
Ilacqua, VA1
Kearney, G1
Asal, NR1
Ociepa-Zawal, M1
Rubis, B1
Wawrzynczak, D1
Wachowiak, R1
Trzeciak, WH1
Hatakeyama, M1
Zou, E1
Steinmetz, R1
Young, PC1
Caperell-Grant, A1
Gize, EA1
Madhukar, BV1
Ben-Jonathan, N1
Bigsby, RM1
Enan, E1
Zheng, T1
Holford, TR1
Mayne, ST1
Owens, PH1
Ward, B1
Carter, D1
Dubrow, R1
Zahm, SH1
Boyle, P1
Tessari, J1
López-Carrillo, L1
López-Cervantes, M1
Torres-Sánchez, L1
Blair, A1
Cebrián, ME1
García, RM1
Coosen, R1
van Velsen, FL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Organochlorine Pesticide Exposure in Residents Near Lake Apopka[NCT02530814]20 participants (Actual)Observational2015-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

12 other studies available for hexachlorocyclohexane and Breast Cancer

ArticleYear
Serum levels of Organochlorine Pesticides and Breast Cancer Risk in Iranian Women.
    Archives of environmental contamination and toxicology, 2019, Volume: 77, Issue:4

    Topics: Adult; Body Mass Index; Breast Neoplasms; Case-Control Studies; Chromatography, Gas; DDT; Dichlorodi

2019
Organochlorine pesticides accumulation and breast cancer: A hospital-based case-control study.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Adipose Tissue; Adult; Aged; Breast Neoplasms; Case-Control Studies; Chlorobenzenes; Chromatography,

2017
The organochlorine pesticides residues in the invasive ductal breast cancer patients.
    Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:3

    Topics: Adipose Tissue; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Chlorobenzenes; Dichlorodi

2015
Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR).
    BMC cancer, 2009, Jul-15, Volume: 9

    Topics: Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; Dioxins;

2009
Associations of serum concentrations of organochlorine pesticides with breast cancer and prostate cancer in U.S. adults.
    Environmental health perspectives, 2010, Volume: 118, Issue:1

    Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Dieldrin; Environmental Pollutants; Female; Hex

2010
Accumulation of environmental estrogens in adipose tissue of breast cancer patients.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2010, Volume: 45, Issue:3

    Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromatography, Gas; DDT; Dichloro

2010
Comparison of the characteristic of estrogenic action patterns of beta-HCH and heregulin beta1 in MCF-7 human breast cancer cells.
    Journal of biochemical and molecular toxicology, 2002, Volume: 16, Issue:5

    Topics: Blotting, Western; Breast Neoplasms; Dimerization; Dose-Response Relationship, Drug; Down-Regulation

2002
Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells.
    Cancer research, 1996, Dec-01, Volume: 56, Issue:23

    Topics: Adenocarcinoma; Animals; Binding, Competitive; Breast Neoplasms; Dose-Response Relationship, Drug; E

1996
Activation of c-Neu tyrosine kinase by o,p'-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells.
    Journal of biochemical and molecular toxicology, 1998, Volume: 12, Issue:2

    Topics: Animals; Breast Neoplasms; Cell-Free System; DDT; Enzyme Activation; Estradiol; Female; Hexachlorocy

1998
Beta-benzene hexachloride in breast adipose tissue and risk of breast carcinoma.
    Cancer, 1999, May-15, Volume: 85, Issue:10

    Topics: Adipose Tissue; Adult; Aged; Breast Neoplasms; Carcinoma; Case-Control Studies; Female; Hexachlorocy

1999
Serum levels of beta-hexachlorocyclohexane, hexachlorobenzene and polychlorinated biphenyls and breast cancer in Mexican women.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2002, Volume: 11, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Environmental Exposure; Female; Hexachlorobenze

2002
Effects of the beta-isomer of hexachlorocyclohexane on estrogen-sensitive human mammary tumor cells.
    Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2

    Topics: Animals; Biotransformation; Breast Neoplasms; Cell Nucleus; Chlorophenols; Cytosol; Dose-Response Re

1989