Page last updated: 2024-08-18

hexachlorobenzene and Porphyrias

hexachlorobenzene has been researched along with Porphyrias in 175 studies

Research

Studies (175)

TimeframeStudies, this research(%)All Research%
pre-1990134 (76.57)18.7374
1990's34 (19.43)18.2507
2000's7 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aldonatti, C; Llambías, EB; San Martín de Viale, LC1
OCKNER, RK; SCHMID, R1
GAJDOS, A; GAJDOS-TOROK, M1
CAN, C; NIGOGOSYAN, G1
BURNETT, JW; PATHAK, MA1
CAMPBELL, JA1
MALKINSON, FD; PEARSON, RW1
de Viale, LC; Lelli, SM; Mazzetti, MB; Taira, MC1
Cárdenas, ML; Chaufan, G; Corvi, MM; Ríos de Molina, Mdel C; San Martín de Viale, LC1
Gerhard, GS; Gorman, N; Robinson, SW; Sinclair, JF; Sinclair, PR; Smith, AG; Trask, HS1
Adzharov, D; Chernev, K; Ivanov, E1
Miura, T; Tagami, H; Torinuki, W1
Billi, SC; Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R1
Debets, FM; Hamers, WJ; Strik, JJ1
Horváth, LI; Kiss, M; Kószó, F; Siklósi, C; Simon, N1
Bender, RC; Buhler, DR; Carpenter, HM; Henderson, MC; Williams, DE1
Cripps, DJ; Dogramici, I; Gocmen, A; Peters, HA1
Ceccarelli-Stanzani, D; Masini, A; Rocchi, E; Trenti, T; Ventura, E1
Ríos de Molina, MC; San Martin de Viale, LC; Taira de Yamasato, MC; Tomio, JM; Wainstok de Calmanovici, R1
Pimstone, NR1
Herbert, M; Ippen, H; Koransky, W; Koss, G; Seubert, A; Seubert, S1
Cole, SP; Marks, GS; Zelt, DT1
Ippen, H; Koransky, W; Koss, G; Seidel, J; Seubert, A; Seubert, S1
Bolsen, K; Goerz, G; Landmann, H; Teschke, R1
Bjørndal, T; Høvding, G; Romslo, I; Sandberg, S1
Goerz, G; Krieg, T; Lissner, R; Sick, N; Vizethum, W1
Day, RS; Disler, PB; Eales, L1
Bolsen, K; Goerz, G; Thier, W1
Catalán Beltrán, T; Chinarro Familiar, S; Enríquez de Salamanca, R; Mas Andrés, V; Molina Ferragut, C; Olmos Andrés, A1
Bryan, GT; Cripps, DJ; Dogramaci, I; Gocmen, A; Peters, HA1
Golf, SW; Graef, V; Tyrell, C1
Elder, GH; Sheppard, DM1
Siegers, CP1
Meyer, HD; Richter, E; Schäfer, SG1
Bańkowska, J2
Rizzardini, M; Smith, AG1
Bolsen, K; Goerz, G; Lissner, R; Staib, AH1
Debets, AJ; Debets, FM; Koss, G; Lössbroek, TG; Reinders, JH; Strik, JJ1
Kószó, F; Siklósi, C; Simon, N2
Kumai, N; Miura, T; Torinuki, W1
Cripps, DJ; Gocmen, A; Peters, HA1
Francis, JE; Smith, AG1
Bolsen, K; Goerz, G; Simon, K; Vizethum, W; Weber, K1
Doss, M; Koss, G; von Tiepermann, R1
De Matteis, F; Francis, JE; Smith, AG1
Blekkenhorst, GH; Day, RS; Eales, L2
Debets, FM; Olie, K; Strik, JJ1
Irifune, H; Tanaka, K; Yoshida, H1
Bloksma, N; Den Besten, C; Schielen, P; Seinen, W; Van Bladeren, PJ; Vos, JG1
Carthew, P; Francis, JE; Ingebrigtsen, K; Smith, AG1
Billi de Catabbi, SC; San Martin de Viale, LC1
Ferramola de Sancovich, AM; Kleiman de Pisarev, DL; Sancovich, HA; Sopena de Kracoff, YE1
Cleton-Soeteman, MI; de Bruijn, WC; Siersema, PD; ten Kate, FJ; van Eijk, HG; Wilson, JH1
Cabral, JR; Carthew, P; Francis, JE; Manson, MM; Smith, AG2
Bartlett, S; Franklin, C; Jarrell, JF; McMahon, A; Singh, A; Valli, VE; Villeneuve, D1
Bennik, MH; Brouwer, A; Bruggeman, I; den Besten, C; Koeman, JH; Kuper, F; Schielen, P; Van Bladeren, PJ; Vos, JG1
Den Besten, C; Haas, J; Rietjens, IM; Steensma, A; van Bladeren, PJ; van Ommen, B; van Tintelen, G1
Barnstorf, W; Bolsen, K; Fritsch, C; Goerz, G; Kalka, K; Tsambaos, D; Winnekendonk, G1
Aldonatti, C; Billi de Catabbi, S; Fernandez, MC; Minutolo, C; San Martín de Viale, L; Sterin-Speziale, N1
Almeida, MG; Aznar, AE; Barros, SB; Davino, SC; Fanini, F; Koch, OR1
Charbonneau, M; Cooper, SF; Legault, N; Sabik, H1
Chlumská, A; Fakan, F; Krijt, J; Michal, M; Safanda, J1
Aldonatti, C; Ríos de Molina, MC; San Martín de Viale, LC; Vilas, GL1
Aldonatti, C; de Calmanovici, RW; de Catabbi, SB; Minutolo, C; San Martin de Viale, LC1
Aldonatti, C; Billi de Catabbi, SC; Fernández-Tomé, MC; San Martin de Viale, LC; Sterin-Speziale, NB1
Aldonatti, C; de Viale, LC1
Billi de Catabbi, SC; Cochón, AC; San Martín de Viale, LC1
Adjarov, D; Apostolov, I; Chernev, K; Dimitrov, P; Drenska, E; Ivanov, E; Krustev, L; Pramatarova, V; Stefanova, M1
Elder, GH; Evans, N; Ferramola, AM; Games, DE; Jackson, AH; Matlin, SA; Sancovich, HA; Smith, SG1
Hazelrigg, D; Jarratt, M1
Bergman, H; Friesen, M; Goldstein, JA; Hass, JR; Hickman, P; Scotti, TM1
Courtney, KD1
Muhlbauer, JE; Pathak, MA1
Benedetto, AV; Taylor, JS1
Goerz, G; Tsambaos, D; Vizethum, W1
Cabral, JR; De Matteis, F; Smith, AG1
Carlson, GP1
De Calmanovici, RW; Ríos De Molina, MD; San Martín De Viale, LC; Tomio, JM1
Bolsen, K; Goerz, G; Krieg, T; Lissner, R; Vizethum, W1
Blekkenhorst, GH; Eales, L1
Cooper, P1
Peters, HA1
Grinstein, M1
Baker, JR; Esber, H; Fleischman, RW; Gralla, EJ; Hagopian, M; Luthra, YK; Marcus, W1
Carstens, M; Louw, M; Neethling, AC; Percy, VA; Shanley, BC1
Blekkenhorst, GH; Eales, L; Pimstone, NR; Webber, BL1
Doss, M; Koss, G; Schermuly, E1
Eichenauer, MG; Goerz, G; Ippen, H; Lissner, R1
Grant, DL; Shields, JB; Villeneuve, DC1
Doyle, M; Jones, K; Magnus, IA; Miura, T1
Brodeur, J; Charbonneau, M; Krishnan, K; Plaa, GL1
Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R; Zenklusen, JC1
Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R1
Brodeur, J; Charbonneau, M; Krishnan, K1
Billi de Catabbi, S; Ríos de Molina, MC; San Martín de Viale, LC2
Bolsen, K; Goerz, G; Jugert, F; Lehmann, P; Merk, HF; Schaefer, T; Scharffetter, K1
Cleton, MI; de Bruijn, WC; Ketelaars, DA; Siersema, PD; van Eijk, HG; van Helvoirt, RP; Wilson, JH1
Cantoni, L; Cuomo, R; De Rosa, G; Di Padova, C; Le Grazie, C; Rizzardini, M; Rizzoli, R; Roda, E; Rodino, S; Simoni, P1
Adjarov, DG1
Francis, JE; Green, JA; Greig, JB; Manson, MM; Smith, AG; Wolf, CR1
Aldonatti, C; Bergoc, R; Cochón, AC; San Martín de Viala, LC; Wainstok de Calmanovici, R1
Conde, C; Enriquez de Salamanca, R; Lopez-Miras, A; Munoz, JJ; To-Figueras, J1
Budillon, G; Cantoni, L; Cuomo, R; Di Padova, C; Le Grazie, C; Rizzardini, M; Rodinò, S1
Kleiman de Pisarev, DL; Rios de Molina, MC; San Martin de Viale, LC1
Adzharov, D1
Kennedy, SW; Wigfield, DC2
Bryan, GT; Cripps, DJ; Gocmen, A; Morris, CR; Peters, HA2
Francis, JE; Green, JA; Manson, MM; Smith, AG; Wolf, CR1
Bacon, BR; Feldman, ES1
Muller-Eberhard, U; Smith, AG; Vincent, SH1
Cabral, JR; Manson, MM; Smith, AG; Stewart, FP1
Rios de Molina, MC; San Martin de Viale, LC; Taira, MC1
Aldonatti, CA; Billi de Catabbi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R1
Edixhoven-Bosdijk, A; Koole-Lesuis, R; Rietveld, T; van den Berg, JW; Visser, O; Wilson, JH1
Bessems, JG; Geesink, G; Hendriks, W; Müller, F; van Bladeren, PJ; van Ommen, B1
Gasiewicz, TA; Goldstein, JA; Hahn, ME; Linko, P1
Adjarov, D; Ivanov, E; Savov, G1
Billi, SC; San Martín de Viale, LC1
Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R2
Basford, D; Krestynski, F; Sweeney, GD1
Bryan, GT; Cripps, DJ; Ertürk, E; Gocmen, A; Morris, CR; Peters, HA1
De Matteis, F2
Bement, WJ; Elder, GH; Gorman, N; Lambrecht, RW; Roberts, AG; Sinclair, JA; Sinclair, PR; Urquhart, AJ1
Cantoni, L; Carugo, C; Graziani, A; Rizzardini, M1
Bird, I; Francis, JE; Smith, AG1
Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R2
Strik, JJ1
Axelson, O1
Ceccarelli, D; Masini, A; Muscatello, U; Trenti, T1
Elder, GH; Roberts, AG; Urquhart, AJ1
Bryan, G; Cripps, D; Ertürk, E; Göcmen, A; Morris, C; Peters, H1
Sweeney, GD1
Cripps, DJ1
Jori, A1
Francis, JE; Smith, AG; Stewart, FP1
Elder, GH; Urquhart, AJ1
Cantoni, L; Graziani, A; Rizzardini, M; Saletti, MC1
Ceccarelli, D; Masini, A; Trenti, T; Ventura, E1
Bolsen, K; Goerz, G; Lissner, R; Merk, H1
De Matteis, F; Ferioli, A; Harvey, C1
Adjarov, DG; Elder, GH1
Buhler, DR; Carpenter, HM1
Billi, SC; Ríos de Molina, Mdel C; San Martín de Viale, LC1
Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R1
Ríos de Molina, Mdel C; San Martín de Viale, LC; Vila, MC; Wainstok de Calmanovici, R1
Bolsen, K; Goerz, G; Lissner, R; Merk, H; Schmitter, H; Seuwen, P1
Bement, WJ; Bonkovsky, HL; Lambrecht, RW; Sinclair, JF; Sinclair, PR1
Elder, GH1
Cripps, DJ; Dogramaci, I; Gocmen, A; Morris, CR; Peters, HA1
Fox, GA; Kennedy, SW; Wigfield, DC1
Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R1
Tangerås, A1
Francis, JE; Greig, JB; Kay, SJ; Smith, AG; Stewart, FP1
Bolsen, K; Goerz, G; Merk, H1
Buhler, DR; Carpenter, HM; Williams, DE3
Bolsen, K; Goerz, G; Merk, H; von Zittwitz, A1
Gorski, JR; Parkinson, A; Rozman, K; Rozman, P1
Alleman, MA; Edixhoven-Bosdijk, A; Koster, JF; Kroos, MJ; Slee, RG; von Eijk, HG; Wilson, JH1
Buhler, DR; Carpenter, HM; Harvey, MJ1
Cabral, JR; Dinsdale, D; Francis, JE; Manson, MM; Smith, AG1
Ceccarelli-Stanzani, D; Masini, A; Tomasi, A; Trenti, T; Ventura, E1
Bolsen, K; Brunner, W; Goerz, G; Lissner, R; Merk, H1
Khanna, RN; Smith, AG1

Reviews

12 review(s) available for hexachlorobenzene and Porphyrias

ArticleYear
Porphyria cutanea tarda.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Age Factors; Animals; Disease Models, Animal; Erythropoiesis; Heme; Hexachlorobenzene; Humans; Hydrocarbons, Halogenated; Iron; Kidney Failure, Chronic; Liver; Photosensitivity Disorders; Porphyrias; Renal Dialysis; Skin Diseases; Skin Pigmentation; Uroporphyrinogen Decarboxylase; Uroporphyrins

1982
Porphyrias and the kidney.
    Nephron, 1981, Volume: 28, Issue:6

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coproporphyrinogens; Coproporphyrins; Hexachlorobenzene; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Lead Poisoning; Porphyrias; Rats; Renal Dialysis; Uroporphyrinogen Decarboxylase; Uroporphyrins

1981
[Experimental porphyria].
    Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53, Issue:6

    Topics: Animals; Disease Models, Animal; Griseofulvin; Hexachlorobenzene; Humans; Mice; Polychlorinated Biphenyls; Porphyrias

1995
Hexachlorobenzene (HCB): a review.
    Environmental research, 1979, Volume: 20, Issue:2

    Topics: Animals; Birds; Chlorobenzenes; Cricetinae; Dogs; Environmental Exposure; Female; Fishes; Food Contamination; Guinea Pigs; Haplorhini; Hexachlorobenzene; Liver; Macaca; Maternal-Fetal Exchange; Mice; Porphyrias; Pregnancy; Rabbits; Sheep; Skin Diseases; Soil Pollutants; Swine; Teratogens

1979
Porphyria cutanea tarda.
    International journal of dermatology, 1979, Volume: 18, Issue:10

    Topics: Adolescent; Aged; Alcoholism; Animals; Chick Embryo; Child; Chloroquine; Diagnosis, Differential; Hexachlorobenzene; Humans; Iron; Kidney Neoplasms; Liver Neoplasms; Middle Aged; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases

1979
Porphyria cutanea tarda. Update 1978.
    Cutis, 1978, Volume: 21, Issue:4

    Topics: Anti-Bacterial Agents; Antimalarials; Estrogens; Hexachlorobenzene; Humans; Liver Neoplasms; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Porphyrias; Uroporphyrinogen Decarboxylase; Uroporphyrins

1978
More light on hexachlorobenzene.
    Food and cosmetics toxicology, 1976, Volume: 14, Issue:4

    Topics: Animals; Chlorobenzenes; Dose-Response Relationship, Drug; Environmental Exposure; Erythrocytes; Female; Fetus; Hexachlorobenzene; Humans; Liver; Male; Occupational Medicine; Pesticide Residues; Porphyrias; Pregnancy; Sex Factors; Species Specificity

1976
Hexachlorobenzene poisoning in Turkey.
    Federation proceedings, 1976, Volume: 35, Issue:12

    Topics: Adolescent; Chlorobenzenes; Edetic Acid; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Infant; Male; Porphyrias; Turkey

1976
Toxicological aspects of liver heme biosynthesis.
    Seminars in hematology, 1988, Volume: 25, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; Hexachlorobenzene; Liver; Porphyrias; Protoporphyrins; Rats; Rats, Gunn

1988
Subacute toxicity of hexachlorobenzene.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Bile; Cats; Chlorobenzenes; Coturnix; Guinea Pigs; Hexachlorobenzene; Liver; Mice; Porphyrias; Rabbits; Rats; Swine

1986
A review of porphyria and cancer and the missing link with human exposure to hexachlorobenzene.
    IARC scientific publications, 1986, Issue:77

    Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Liver Cirrhosis; Liver Neoplasms; Lymphoma; Neoplasms; Porphyrias; Sarcoma; Skin Diseases

1986
Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases.
    Clinical biochemistry, 1986, Volume: 19, Issue:1

    Topics: Animals; Bloodletting; Carboxy-Lyases; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Heme; Hexachlorobenzene; Humans; Hydroxamic Acids; Iron; Lead Poisoning; Male; Mice; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases; Uroporphyrinogen Decarboxylase

1986

Other Studies

163 other study(ies) available for hexachlorobenzene and Porphyrias

ArticleYear
Tryptophan metabolism via serotonin in rats with hexachlorobenzene experimental porphyria.
    Biochemical pharmacology, 2003, Jul-01, Volume: 66, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, High Pressure Liquid; Digestive System; Disease Models, Animal; Fungicides, Industrial; Hexachlorobenzene; Humans; Liver; Porphyria Cutanea Tarda; Porphyrias; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase

2003
Acquired porphyria in man and rat due to hexachlorobenzene intoxication.
    Nature, 1961, Feb-11, Volume: 189

    Topics: Animals; Benzene Derivatives; Hexachlorobenzene; Humans; Male; Porifera; Porphyrias; Rats

1961
[Experimental porphyria in the white rat induced by hexachlorobenzene. Therapeutic action of adenosine-5-monophosphoric acid].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1961, Volume: 155

    Topics: Adenine Nucleotides; Adenosine; Animals; Hexachlorobenzene; Hexachlorocyclohexane; Porifera; Porphyrias; Rats

1961
Acquired toxic porphyria cutanea tarda due to hexachlorobenzene. Report of 348 cases caused by this fungicide.
    JAMA, 1963, Jan-12, Volume: 183

    Topics: Antifungal Agents; Cyclohexanes; Hexachlorobenzene; Humans; Porphyria Cutanea Tarda; Porphyrias

1963
EFFECT OF LIGHT UPON PORPHYRIN METABOLISM OF RATS. STUDY OF PORPHYRIN METABOLISM OF NORMAL RATS AND RATS WITH HEXACHLOROBENZENE-INDUCED PORPHYRIA.
    Archives of dermatology, 1964, Volume: 89

    Topics: Hexachlorobenzene; Hexachlorocyclohexane; Humans; Light; Liver; Metabolism; Porphyrias; Porphyrins; Rats; Research; Ultraviolet Rays; Urine

1964
PATHOLOGICAL ASPECTS OF HEXACHLOROBENZENE FEEDING IN RATS.
    South African journal of laboratory and clinical medicine. Suid-Afrikaanse tydskrif vir laboratorium- en kliniekwerk, 1963, Volume: 14

    Topics: Erythrocytes; Fluorescence; Hexachlorobenzene; Hexachlorocyclohexane; Histocytochemistry; Lipids; Liver; Pathology; Pigments, Biological; Porphyrias; Rats; Research; Toxicology

1963
SOME OBSERVATIONS ON HEXACHLOROBENZENE INDUCED EXPERIMENTAL PORPHYRIA.
    The Journal of investigative dermatology, 1965, Volume: 44

    Topics: Alcohols; Animals; Blister; Dentin; Dermatitis, Phototoxic; Ethanol; Fluorescence; Guinea Pigs; Hair; Hexachlorobenzene; Hexachlorocyclohexane; Microscopy; Microscopy, Fluorescence; Pathology; Pharmacology; Photosensitivity Disorders; Porphyrias; Porphyrins; Rats; Research; Skin; Tooth; Toxicology; Ultraviolet Rays; Urine

1965
Glycogen metabolism and glucose transport in experimental porphyria.
    Toxicology, 2004, Apr-15, Volume: 197, Issue:2

    Topics: Animals; Disease Models, Animal; Female; Fungicides, Industrial; Gluconeogenesis; Glucose; Glycogen; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar

2004
Abnormal kinetic behavior of uroporphyrinogen decarboxylase obtained from rats with hexachlorobenzene-induced porphyria.
    Journal of biochemical and molecular toxicology, 2005, Volume: 19, Issue:1

    Topics: Animals; Female; Hexachlorobenzene; Kinetics; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

2005
Hexachlorobenzene stimulates uroporphyria in low affinity AHR mice without increasing CYP1A2.
    Toxicology and applied pharmacology, 2007, Jun-01, Volume: 221, Issue:2

    Topics: Animals; Cytochrome P-450 CYP1A2; Female; Hemochromatosis Protein; Hexachlorobenzene; Histocompatibility Antigens Class I; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mutation; Porphyrias; Receptors, Aryl Hydrocarbon; Sex Factors; Uroporphyrins

2007
[Induction of mixed microsomal oxidase in experimental hexachlorobenzene porphyria in rabbits].
    Eksperimentalna meditsina i morfologiia, 1981, Volume: 20, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; gamma-Glutamyltransferase; Hexachlorobenzene; Microsomes, Liver; Oxidoreductases; Porphyrias; Rabbits; Skin Diseases

1981
Activation of the alternative complement pathway by 405 nm light in serum from porphyric rat.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:5

    Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement Activation; Complement Pathway, Alternative; Female; Hexachlorobenzene; Neutrophils; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases; Ultraviolet Rays

1984
[Experimental porphyria induced by chlorinated hydrocarbons. Studies of porphyrinogen carboxy-lyase in the experimental model of human cutaneous delayed porphyria].
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1984, Volume: 34, Issue:4

    Topics: Animals; Carboxy-Lyases; Disease Models, Animal; Female; Hexachlorobenzene; Hot Temperature; Liver; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases

1984
Metabolism as a prerequisite for the porphyrinogenic action of polyhalogenated aromatics, with special reference to hexachlorobenzene and polybrominated biphenyls (Firemaster BP-6).
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: 5-Aminolevulinate Synthetase; Animals; Biotransformation; Biphenyl Compounds; Cells, Cultured; Chick Embryo; Chlorobenzenes; Enzyme Induction; Heme; Hexachlorobenzene; Liver; Polybrominated Biphenyls; Porphyrias; Porphyrins; Spectrometry, Fluorescence

1980
The role of possible membrane damage in porphyria cutanea tarda: a spin label study of rat liver cell membranes.
    Biochemical pharmacology, 1982, Jan-01, Volume: 31, Issue:1

    Topics: Animals; Cell Membrane; Cell Separation; Electron Spin Resonance Spectroscopy; Ethanol; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Skin Diseases; Spin Labels

1982
Hexachlorobenzene-induced porphyria in Japanese quail. Effect of pretreatment with phenobarbital or beta-naphthoflavone.
    Biochemical pharmacology, 1984, Dec-01, Volume: 33, Issue:23

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Flavonoids; Glutathione Transferase; Hexachlorobenzene; Liver; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Phenobarbital; Porphyrias

1984
Porphyria turcica due to hexachlorobenzene: a 20 to 30 year follow-up study on 204 patients.
    The British journal of dermatology, 1984, Volume: 111, Issue:4

    Topics: Adult; Chlorobenzenes; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Male; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey

1984
Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria.
    Biochemical and biophysical research communications, 1984, Jan-13, Volume: 118, Issue:1

    Topics: Animals; Female; Hexachlorobenzene; Iron; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1984
Mechanism of hexachlorobenzene-induced porphyria in rats. Effect of phenobarbitone pretreatment.
    The Biochemical journal, 1984, Mar-15, Volume: 218, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Ferrochelatase; Hexachlorobenzene; Hydroxymethylbilane Synthase; Liver; Organ Size; Phenobarbital; Porphobilinogen Synthase; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1984
Hexachlorobenzene and 2, 4, 5, 2; 4; 5'-hexachlorobiphenyl - a comparison of their distribution, biotransformation and porphyrinogenic action in female rats.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Biotransformation; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Polychlorinated Biphenyls; Porphyrias; Porphyrins; Rats; Tissue Distribution

1980
Alterations in the heme biosynthetic pathway as an index of exposure to toxins.
    Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:7

    Topics: Cytochrome P-450 Enzyme System; Environmental Pollutants; Heme; Hexachlorobenzene; Hydrocarbons, Chlorinated; Lead; Polychlorinated Biphenyls; Porphyrias; Porphyrins

1982
Studies on the toxicology of hexachlorobenzene. V. Different phases of porphyria during and after treatment.
    Archives of toxicology, 1983, Volume: 52, Issue:1

    Topics: Animals; Chlorobenzenes; Cytosol; Female; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors; Uroporphyrinogen Decarboxylase

1983
Effect of hexachlorobenzene on the activities of hepatic alcohol metabolizing enzymes.
    Biochemical pharmacology, 1983, Jun-01, Volume: 32, Issue:11

    Topics: Animals; Chlorobenzenes; Disease Models, Animal; Ethanol; Female; Hexachlorobenzene; Liver; Liver Diseases; Porphyrias; Rats; Rats, Inbred Strains

1983
Porphyrin-induced photodamage as related to the subcellular localization of the porphyrins.
    Acta dermato-venereologica. Supplementum, 1982, Volume: 100

    Topics: Animals; Female; Griseofulvin; Hexachlorobenzene; Humans; Liver; Lysosomes; Male; Middle Aged; Mitochondria, Liver; Photosensitivity Disorders; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Skin Diseases

1982
[Influence of p-amino-benzoic acid on the hexachlorobenzene induced porphyria in the rat (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:5

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Aminolevulinic Acid; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Glycine; Hexachlorobenzene; Porphobilinogen; Porphyrias; Porphyrins; Rats

1980
[Influence of silymarin and (+)-cyanidanol-3 on the HCB-induced porphyria in rats (author's transl)].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:1

    Topics: Animals; Benzopyrans; Catechin; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Flavins; Flavonoids; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Silymarin

1982
[Induction of experimental porphyria by hexachlorobenzene in rats].
    Revista espanola de las enfermedades del aparato digestivo, 1982, Volume: 62, Issue:1

    Topics: Animals; Chlorobenzenes; Disease Models, Animal; Female; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases

1982
Epidemiology of hexachlorobenzene-induced porphyria in Turkey: clinical and laboratory follow-up after 25 years.
    Archives of neurology, 1982, Volume: 39, Issue:12

    Topics: Adult; Chlorobenzenes; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Male; Maternal-Fetal Exchange; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey

1982
Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene.
    Archives of toxicology, 1982, Volume: 50, Issue:3-4

    Topics: Animals; Chlorobenzenes; Etiocholanolone; Female; Flutamide; Hexachlorobenzene; Liver; Oxidoreductases; Porphyrias; Porphyrins; Rats; Stereoisomerism; Steroids

1982
Immunoreactive uroporphyrinogen decarboxylase is unchanged in porphyria caused by TCDD and hexachlorobenzene.
    Biochemical and biophysical research communications, 1982, Nov-16, Volume: 109, Issue:1

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Dioxins; Disease Models, Animal; Hexachlorobenzene; Immune Sera; Immunoelectrophoresis, Two-Dimensional; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Uroporphyrinogen Decarboxylase

1982
[Effect of silymarin and (+)-cyanidanol-3 on hexachlorobenzene(HCB)-induced porphyria in rats].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:12

    Topics: Animals; Benzopyrans; Catechin; Chlorobenzenes; Disease Models, Animal; Flavonoids; Hexachlorobenzene; Liver Diseases; Porphyrias; Rats; Research Design; Silymarin

1982
Iron absorption during the development of hexachlorobenzene-induced porphyria in rats.
    Archives of dermatological research, 1982, Volume: 274, Issue:3-4

    Topics: Acute Disease; Animals; Female; Hexachlorobenzene; Intestinal Absorption; Iron; Jejunum; Liver; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Skin Diseases

1982
[Hepatotoxicity of selected polychlorinated aromatic hydrocarbons].
    Roczniki Panstwowego Zakladu Higieny, 1982, Volume: 33, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Dioxins; Hexachlorobenzene; Liver; Pentachlorophenol; Polychlorinated Dibenzodioxins; Porphyrias; Rats

1982
Sex differences in the metabolism of hexachlorobenzene by rats and the development of porphyria in females.
    Biochemical pharmacology, 1982, Nov-15, Volume: 31, Issue:22

    Topics: Animals; Bile; Chlorobenzenes; Diethylstilbestrol; Female; Hexachlorobenzene; Liver; Male; Pentachlorophenol; Phenols; Porphyrias; Rats; Rats, Inbred F344; Sex Factors; Time Factors

1982
[Influence of theophylline on hexachlorobenzene induced porphyria (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:9

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Hexachlorobenzene; Liver; Mixed Function Oxygenases; Organ Size; Porphyrias; Proteins; Rats; Rats, Inbred Strains; Theophylline

1981
Biotransformation and porphyringogenic action of hexachlorobenzene and its metabolites in a primary liver cell culture.
    Toxicology, 1981, Volume: 19, Issue:3

    Topics: Animals; Biotransformation; Cells, Cultured; Chick Embryo; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase

1981
[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)].
    Dermatosen in Beruf und Umwelt. Occupation and environment, 1981, Volume: 29, Issue:2

    Topics: Animals; Chloranil; Chlorobenzenes; Hexachlorobenzene; Pentachlorophenol; Porphyrias; Porphyrins; Rats

1981
Histopathological studies on sun-exposed hexachlorobenzene-induced porphyric rat skin.
    The Tohoku journal of experimental medicine, 1981, Volume: 134, Issue:4

    Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred Strains; Skin; Sunlight

1981
Porphyria turcica. Twenty years after hexachlorobenzene intoxication.
    Archives of dermatology, 1980, Volume: 116, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Child; Child, Preschool; Chlorobenzenes; Female; Follow-Up Studies; Food Contamination; Hexachlorobenzene; Humans; Infant; Infant, Newborn; Male; Middle Aged; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey

1980
Relative abilities on a molar basis of hexafluoro-, hexachloro- and hexabromobenzenes to decrease liver uroporphyrinogen decarboxylase activity and cause porphyria in female rats.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:2

    Topics: Animals; Body Weight; Bromobenzenes; Carboxy-Lyases; Chlorobenzenes; Diet; Enzyme Induction; Female; Fluorocarbons; Hexachlorobenzene; Liver; Organ Size; Porphyrias; Rats; Uroporphyrinogen Decarboxylase

1980
[Influence of chloroquine on the hexachlorobenzene-induced porphyria. Investigations in the skin, liver, and urine (author's transl)].
    Archives of dermatological research, 1980, Volume: 267, Issue:2

    Topics: Animals; Chloroquine; Female; Hexachlorobenzene; Iron; Liver; Porphyrias; Porphyrins; Rats; Skin

1980
Uroporphyrinogen decarboxylase deficiency in experimental chronic hepatic porphyria.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1980, Volume: 361, Issue:8

    Topics: Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Erythrocytes; Female; Hexachlorobenzene; Liver; Liver Diseases; Porphyrias; Rats; Uroporphyrinogen Decarboxylase

1980
Lobes of rat liver respond at different rates to challenge by dietary hexachlorobenzene.
    Biochemical pharmacology, 1980, Dec-01, Volume: 29, Issue:23

    Topics: Animals; Chlorobenzenes; Female; Glutathione; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase

1980
Drug induced acute porphyric episodes in rats.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Animals; Feces; Female; Hexachlorobenzene; Intestinal Mucosa; Kidney; Kinetics; Liver; Male; Phenylbutazone; Porphyrias; Porphyrins; Rats

1980
The effect of bleeding and iron administration on the development of hexachlorobenzene-induced rat porphyria.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Animals; Blood; Colon; Female; Hexachlorobenzene; Iron; Kidney; Liver; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase

1980
Effects of pentachlorophenol on rat liver changes induced by hexachlorobenzene, with special reference to porphyria, and alterations in mixed function oxygenases.
    Toxicology, 1980, Volume: 15, Issue:3

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Female; Gas Chromatography-Mass Spectrometry; Hexachlorobenzene; Liver; Microsomes, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats

1980
Immune effects of hexachlorobenzene in the rat: role of metabolism in a 13-week feeding study.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antibody Specificity; Autoantigens; Biotransformation; Body Weight; Female; Hexachlorobenzene; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lymphatic Diseases; Lymphoid Tissue; Organ Size; Porphyrias; Rats; Rats, Wistar; Skin; Skin Diseases; Splenomegaly; Troleandomycin

1995
Influence of iron on the induction of hepatic tumors and porphyria by octachlorostyrene in C57BL/10ScSn mice.
    Cancer letters, 1994, Jun-30, Volume: 81, Issue:2

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Environmental Pollutants; Hexachlorobenzene; Iron; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Porphyrias; Styrenes

1994
Studies on the active centre(s) of rat liver porphyrinogen carboxy-lyase. In vivo effect of hexachlorobenzene on decarboxylation site(s) of porphyrinogens.
    The International journal of biochemistry, 1994, Volume: 26, Issue:4

    Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Decarboxylation; Diacetyl; Female; Hexachlorobenzene; Histidine; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar

1994
Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:5

    Topics: Animals; Carboxy-Lyases; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Wistar; Thyroidectomy; Thyroxine; Triiodothyronine

1994
Ferritin accumulation and uroporphyrin crystal formation in hepatocytes of C57BL/10 mice: a time-course study.
    Cell and tissue research, 1993, Volume: 274, Issue:2

    Topics: Animals; Crystallization; Drug Synergism; Ferritins; Hexachlorobenzene; Iron-Dextran Complex; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Porphyrias; Time Factors; Uroporphyrins

1993
Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Animals; Carcinogens; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glutathione Transferase; Hexachlorobenzene; Iron; Liver; Liver Neoplasms; Porphyrias; Rats; Rats, Inbred F344

1993
Hexachlorobenzene toxicity in the monkey primordial germ cell without induced porphyria.
    Reproductive toxicology (Elmsford, N.Y.), 1993, Volume: 7, Issue:1

    Topics: Animals; Female; Fertilization in Vitro; Germ Cells; Hexachlorobenzene; Liver; Liver Function Tests; Macaca fascicularis; Oocytes; Ovarian Follicle; Porphyrias; Porphyrins; Pregnancy; Tissue Distribution

1993
The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study.
    Toxicology and applied pharmacology, 1993, Volume: 119, Issue:2

    Topics: Animals; Biotransformation; Body Weight; Chlorobenzenes; Eating; Female; Hexachlorobenzene; Homeostasis; Liver; Organ Size; Oxidation-Reduction; Phencyclidine; Porphyrias; Porphyrins; Rats; Rats, Wistar; Retinoids; Thyroid Hormones; Troleandomycin

1993
Comparative biotransformation of hexachlorobenzene and hexafluorobenzene in relation to the induction of porphyria.
    European journal of pharmacology, 1995, Dec-07, Volume: 293, Issue:4

    Topics: Animals; Biotransformation; Female; Fluorocarbons; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar

1995
Influence of UVA and UVB irradiation on hepatic and cutaneous P450 isoenzymes.
    Archives of dermatological research, 1996, Volume: 289, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glutathione; Hexachlorobenzene; Humans; Isoenzymes; Liver; Oxidoreductases, N-Demethylating; Porphyrias; Rats; Rats, Wistar; Skin; Ultraviolet Rays

1996
Time course of hexachlorobenzene-induced alterations of lipid metabolism and their relation to porphyria.
    The international journal of biochemistry & cell biology, 1997, Volume: 29, Issue:2

    Topics: Animals; Female; Fungicides, Industrial; Hexachlorobenzene; Lipid Metabolism; Lipid Peroxidation; Porphyrias; Rats; Rats, Wistar

1997
Pro- and anti-oxidant parameters in rat liver after short-term exposure to hexachlorobenzene.
    Human & experimental toxicology, 1997, Volume: 16, Issue:5

    Topics: Animals; Coproporphyrins; Cytochrome P-450 Enzyme System; Erythrocytes; Fungicides, Industrial; Glutathione Peroxidase; Hexachlorobenzene; Liver; Male; Oxidative Stress; Porphyrias; Rats; Rats, Wistar

1997
Effect of estradiol on the induction of porphyria by hexachlorobenzene in the rat.
    Biochemical pharmacology, 1997, Jul-01, Volume: 54, Issue:1

    Topics: Animals; Castration; Estradiol; Female; Hexachlorobenzene; Inactivation, Metabolic; Male; Porphyrias; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sulfhydryl Compounds; Uroporphyrins

1997
Liver cell cytoplasmic inclusions in experimental porphyrias: their demonstration with the ferric ferricyanide reduction reaction.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1997, Volume: 49, Issue:3-4

    Topics: Animals; Benzamides; Disease Models, Animal; Female; Ferricyanides; Fungicides, Industrial; Herbicides; Hexachlorobenzene; Humans; Inclusion Bodies; Liver; Mice; Oxidation-Reduction; Polychlorinated Biphenyls; Porphyria Cutanea Tarda; Porphyrias; Rats; Rats, Wistar

1997
Effect of alpha lipoic acid amide on hexachlorobenzene porphyria.
    Biochemistry and molecular biology international, 1999, Volume: 47, Issue:5

    Topics: Animals; Female; Free Radical Scavengers; Hexachlorobenzene; Porphyrias; Rats; Rats, Wistar; Thioctic Acid; Time Factors

1999
Porphyria-induced hepatic porphyrinogen carboxy-lyase inhibitor and its interaction with the active site(s) of the enzyme.
    Biochemistry and molecular biology international, 1999, Volume: 47, Issue:6

    Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Enzyme Inhibitors; Female; Hexachlorobenzene; Humans; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar; Uroporphyrinogens

1999
Heme metabolism and lipid peroxidation in rat kidney hexachlorobenzene-induced porphyria: A compartmentalized study of biochemical pathogenic mechanisms.
    Kidney & blood pressure research, 2000, Volume: 23, Issue:1

    Topics: Animals; Biomarkers; Enzyme Inhibitors; Female; Heme; Hexachlorobenzene; Kidney; Kidney Cortex; Lipid Peroxidation; Liver; Malondialdehyde; Porphyrias; Porphyrins; Rats; Rats, Wistar; Uroporphyrinogen Decarboxylase

2000
Heme metabolism after discontinued hexachlorobenzene administration in rats: possible irreversible changes and biomarker for hexachlorobenzene persistence.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2000, Volume: 127, Issue:2

    Topics: Adipose Tissue; Animals; Animals, Outbred Strains; Biomarkers; Drug Administration Schedule; Enzyme Inhibitors; Female; Fungicides, Industrial; Heme; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Wistar; Time Factors; Uroporphyrinogen Decarboxylase

2000
Phospholipid alterations elicited by hexachlorobenzene in rat brain are strain-dependent and porphyria-independent.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 130, Issue:2

    Topics: Animals; Brain; Female; Hexachlorobenzene; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Porphyrias; Porphyrins; Rats; Rats, Wistar; Species Specificity; Sphingomyelins

2001
Studies on the mechanism of the changes in serum and liver gamma-glutamyl transpeptidase activity. II. Experimental hexachlorobenzene porphyria in rabbits.
    Enzyme, 1976, Volume: 21, Issue:1

    Topics: Acetylglucosaminidase; Animals; gamma-Glutamyltransferase; Hexachlorobenzene; Liver; Mannosidases; Porphyrias; Porphyrins; Rabbits

1976
Macrocyclic intermediates in the biosynthesis of porphyrins.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1976, Feb-05, Volume: 273, Issue:924

    Topics: Animals; Chickens; Coproporphyrinogens; Hexachlorobenzene; Humans; Porphyrias; Porphyrins; Protoporphyrins; Rats; Uroporphyrinogens

1976
Letter: Gamma-benzene hexachloride toxicity.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Hexachlorobenzene; Hexachlorocyclohexane; Humans; Infant; Isomerism; Liver; Porphyrias; Scabies; Structure-Activity Relationship

1975
Assessment of the contribution of chlorinated dibenzo-p-dioxins and dibenzofurans to hexachlorobenzene-induced toxicity, porphyria, changes in mixed function oxygenases, and histopathological changes.
    Toxicology and applied pharmacology, 1978, Volume: 46, Issue:3

    Topics: Animals; Benzofurans; Body Weight; Chlorobenzenes; Dioxins; Drug Contamination; Female; Hexachlorobenzene; Liver; Lung; Mixed Function Oxygenases; Polychlorinated Biphenyls; Porphyrias; Rats

1978
Cutaneous cytochrome P-450 activity during hexachlorobenzene-induced experimental porphyria in rats.
    Archives of dermatological research, 1979, May-29, Volume: 265, Issue:1

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Microsomes; Microsomes, Liver; Porphyrias; Rats; Skin

1979
A difference between two strains of rats in their liver non-haem iron content and in their response to the porphyrogenic effect of hexachlorobenzene.
    Chemico-biological interactions, 1979, Volume: 27, Issue:2-3

    Topics: 5-Aminolevulinate Synthetase; Animals; Dicarbethoxydihydrocollidine; Female; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase

1979
Chlorinated benzene induction of hepatic porphyria.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Organ Size; Porphyrias; Rats

1977
Porphyrins and porphyrinogen carboxy-lase in hexachlorobenzene-induced porphyria.
    The Biochemical journal, 1977, Dec-15, Volume: 168, Issue:3

    Topics: Animals; Carboxy-Lyases; Chromatography, Gel; Female; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Tissue Distribution; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

1977
Hexachlorobenzene porphyria and hexachlorobenzene catabolism in rats.
    Biochemical and biophysical research communications, 1978, Feb-28, Volume: 80, Issue:4

    Topics: Adipose Tissue; Animals; Chlorobenzenes; Feces; Female; Hexachlorobenzene; Kinetics; Liver; Male; Porphyrias; Rats

1978
[Porphyria symptoms and microsomal enzyme activity in rat liver following administration of hexachlorobenzene].
    Roczniki Panstwowego Zakladu Higieny, 1978, Volume: 29, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorobenzenes; Female; Hexachlorobenzene; Microsomes, Liver; Porphyrias; Rats

1978
[Hexachlorbenzene (HCB) induced porphyria in rats. Influence of HCB-metabolites on the biosynthesis of heme (author's transl)].
    Archives of dermatological research, 1978, Nov-10, Volume: 263, Issue:2

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Pentachlorophenol; Porphyrias; Rats

1978
The use of the rat in the experimental investigation of the porphyrias.
    Journal of the South African Veterinary Association, 1978, Volume: 49, Issue:3

    Topics: Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Drug Evaluation, Preclinical; Female; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Uroporphyrins

1978
Simplified method for the determination of porphyrins in body fluids.
    Analytical biochemistry, 1977, Volume: 77, Issue:2

    Topics: Animals; Hexachlorobenzene; Humans; Lead Poisoning; Methods; Porphyrias; Porphyrins; Rabbits; Rats

1977
Toxic effects of hexachlorobenzene after daily administration to beagle dogs for one year.
    Toxicology and applied pharmacology, 1977, Volume: 40, Issue:2

    Topics: Adipose Tissue; Animals; Bile; Body Weight; Chlorobenzenes; Dogs; Female; Hexachlorobenzene; Leukocyte Count; Male; Neutrophils; Porphyrias; Porphyrins; Rats; Time Factors

1977
Effects of hexachlorobenzene feeding and iron overload on enzymes of haem biosynthesis and cytochrome P 450 in rat liver.
    Clinical science and molecular medicine, 1977, Volume: 53, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Siderosis; Time Factors; Uroporphyrinogen Decarboxylase

1977
Hepatic haem metabolism in porphyria cutanea tarda (PCT): enzymatic studies and their relation to liver ultrastructure.
    Annals of clinical research, 1976, Volume: 8 Suppl 17

    Topics: Aminopyrine; Animals; Benzopyrenes; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Hexachlorobenzene; Humans; Hydroxylation; Iron; Liver; Microscopy, Electron; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats

1976
Hexachlorobenzene porphyria in rats as a model for human chronic hepatic porphyrias.
    Annals of clinical research, 1976, Volume: 8 Suppl 17

    Topics: Aminolevulinic Acid; Animals; Chlorobenzenes; Chronic Disease; Coproporphyrins; Disease Models, Animal; Female; Hexachlorobenzene; Kidney; Liver; Porphyrias; Porphyrins; Protoporphyrins; Rats; Spleen; Uroporphyrins

1976
Hexachlorobenzene-induced porphyria in rats--relationship between prophyrin excretion and induction of drug metabolizing liver enzymes.
    Biochemical pharmacology, 1975, Sep-15, Volume: 24, Issue:18

    Topics: Aminolevulinic Acid; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Hexachlorobenzene; Liver; Male; Porphyrias; Porphyrins; Proteins; Rats; Time Factors; Triglycerides

1975
Chemical (HCB) porphyria: effect of removal of sex organs in the rat.
    Bulletin of environmental contamination and toxicology, 1975, Volume: 14, Issue:4

    Topics: Animals; Castration; Chlorobenzenes; Diet; Female; Hexachlorobenzene; Liver; Male; Ovary; Porphyrias; Porphyrins; Rats; Sex Factors; Testis; Time Factors

1975
Skin porphyrin and photosensitivity in the porphyric rat.
    Dermatologica, 1975, Volume: 151, Issue:2

    Topics: Animals; Feces; Female; Hexachlorobenzene; Light; Male; Porphyrias; Porphyrins; Rats; Skin

1975
Modulation of hexachlorobenzene-induced hepatic porphyria by methyl isobutyl ketone in the rat.
    Toxicology letters, 1992, Volume: 61, Issue:2-3

    Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Female; Hexachlorobenzene; Liver Diseases; Methyl n-Butyl Ketone; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1992
Influence of hepatic tumors caused by diethylnitrosamine on hexachlorobenzene-induced porphyria in rats.
    Cancer letters, 1991, Jul-04, Volume: 58, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Hexachlorobenzene; Liver; Liver Neoplasms; Porphobilinogen; Porphyrias; Porphyrins; Rats

1991
Sex comparison of heme pathway in rats bearing hepatic tumors.
    Tumori, 1991, Oct-31, Volume: 77, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hydroxymethylbilane Synthase; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Sex Characteristics

1991
Development of an experimental model for the study of hexachlorobenzene-induced hepatic porphyria in the rat.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 17, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Hexachlorobenzene; Liver; Liver Diseases; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrins

1991
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Mechanism of drug action.
    The International journal of biochemistry, 1991, Volume: 23, Issue:7-8

    Topics: Animals; Binding Sites; Chromatography, Gel; Copper; Copper Sulfate; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hot Temperature; Liver; Pentachlorophenol; Porphyrias; Porphyrins; Protein Conformation; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Spectrophotometry

1991
Studies on the active centre of rat liver porphyrinogen carboxylase in vivo effect of hexachlorobenzene.
    The International journal of biochemistry, 1991, Volume: 23, Issue:7-8

    Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Diethyl Pyrocarbonate; Epoxy Compounds; Female; Hexachlorobenzene; Histidine; Hydroxylamine; Hydroxylamines; Liver; Methylene Blue; Photochemistry; Porphyrias; Rats; Rats, Inbred Strains; Spectrophotometry; Uroporphyrinogens

1991
Effect of UVASUN on porphyrin metabolism and P-450 isoenzymes in hexachlorobenzene-induced porphyric rats.
    Current problems in dermatology, 1991, Volume: 20

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Isoenzymes; Liver Diseases; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Nude; Skin; Skin Diseases; Ultraviolet Rays

1991
Iron and uroporphyrin in hepatocytes of inbred mice in experimental porphyria: a biochemical and morphological study.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:6

    Topics: Animals; Drug Combinations; Hexachlorobenzene; Iron; Iron-Dextran Complex; Liver; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Porphyrias; Uroporphyrins

1991
Bile and biliary lipid secretion in rats with hexachlorobenzene-induced porphyria. Effect of S-adenosyl-L-methionine administration.
    Journal of hepatology, 1991, Volume: 12, Issue:1

    Topics: Animals; Bile; Bile Ducts; Bilirubin; Cholesterol; Female; Hexachlorobenzene; Injections, Subcutaneous; Lipid Metabolism; Liver; Organ Size; Phospholipids; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1991
Decreased activity of liver coproporphyrinogen oxidase in hexachlorobenzene-induced porphyria.
    Experimental pathology, 1990, Volume: 40, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Coproporphyrinogen Oxidase; Coproporphyrins; Hexachlorobenzene; Hydrogen-Ion Concentration; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Porphyrias; Time Factors

1990
Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls.
    Biochemical pharmacology, 1990, Nov-01, Volume: 40, Issue:9

    Topics: Animals; Aroclors; Chemical and Drug Induced Liver Injury; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Immunohistochemistry; Liver Diseases; Male; Microsomes, Liver; Oxidation-Reduction; Polybrominated Biphenyls; Porphyrias; Rats; Rats, Inbred F344; Sex Factors; Uroporphyrinogen Decarboxylase; Uroporphyrins

1990
Synergistic effect of mammary tumors on hexachlorobenzene-induced porphyria in rats.
    Cancer letters, 1990, Nov-19, Volume: 55, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Animals; Female; Hexachlorobenzene; Mammary Neoplasms, Experimental; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1990
Is hexachlorobenzene human overload related to porphyria cutanea tarda? A speculative hypothesis.
    Medical hypotheses, 1990, Volume: 33, Issue:1

    Topics: Body Burden; Environmental Exposure; Hexachlorobenzene; Humans; Porphyrias; Skin Diseases; Spain

1990
Protective effect of S-adenosyl-L-methionine in hepatic uroporphyria. Evaluation in an experimental model.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Hexachlorobenzene; Liver Diseases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Skin Diseases; Uroporphyrinogen Decarboxylase

1990
Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria.
    Biochemical pharmacology, 1990, Mar-01, Volume: 39, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Chlorobenzenes; Dose-Response Relationship, Drug; Female; Hexachlorobenzene; Iodine Radioisotopes; Liver; Organ Size; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroxine; Triiodothyronine

1990
[Study of the origin of urinary porphyrins in experimental hexachlorobenzene-induced porphyria ].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 109, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Hexachlorobenzene; Kidney; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase; Uroporphyrins

1990
Dose-response relationships in hexachlorobenzene-induced porphyria.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Chlorobenzenes; Dose-Response Relationship, Drug; Female; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Inbred Strains; Tissue Distribution

1990
Hexachlorobenzene episode in Turkey.
    Biomedical and environmental sciences : BES, 1989, Volume: 2, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Chlorobenzenes; Disease Outbreaks; Feces; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Infant; Male; Milk, Human; Porphyrias; Porphyrins; Skin Diseases; Turkey

1989
Sexual dimorphism of cytochrome P-450 induction by hexachlorobenzene in rats.
    Biochemical Society transactions, 1989, Volume: 17, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Liver; Liver Neoplasms, Experimental; Male; Porphyrias; Rats; Rats, Inbred F344; Sex Characteristics

1989
Hepatic mitochondrial oxidative metabolism and lipid peroxidation in experimental hexachlorobenzene-induced porphyria with dietary carbonyl iron overload.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Diet; Female; Hexachlorobenzene; Iron; Iron Carbonyl Compounds; Lipid Peroxidation; Mitochondria, Liver; Organometallic Compounds; Oxidation-Reduction; Oxygen Consumption; Porphyrias; Rats; Rats, Inbred Strains

1989
Modulation of hepatic heme-binding Z protein in mice by the porphyrogenic carcinogens griseofulvin and hexachlorobenzene.
    Cancer letters, 1989, Volume: 45, Issue:2

    Topics: Animals; Blotting, Western; Carcinogens; Carrier Proteins; Chlorobenzenes; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Griseofulvin; Heme; Heme-Binding Proteins; Hemeproteins; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Porphyrias

1989
Hexachlorobenzene as a promoter of diethylnitrosamine-initiated hepatocarcinogenesis in rats and comparison with induction of porphyria.
    Carcinogenesis, 1989, Volume: 10, Issue:7

    Topics: Animals; Body Weight; Carcinogens; Chlorobenzenes; Diethylnitrosamine; Female; Hexachlorobenzene; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Porphyrias; Rats; Rats, Inbred F344; Reference Values; Sex Factors

1989
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Studies on their properties.
    The International journal of biochemistry, 1989, Volume: 21, Issue:2

    Topics: Animals; Chlorobenzenes; Enzyme Stability; Ferrochelatase; Heme; Hexachlorobenzene; Hydrogen-Ion Concentration; Lyases; Mitochondria, Liver; Porphyrias; Rats

1989
Influence of the strain of rats on the induction of hexachlorobenzene induced porphyria.
    The International journal of biochemistry, 1989, Volume: 21, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Liver; Liver Diseases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Species Specificity

1989
Development of hexachlorobenzene porphyria in rats: time sequence and relationship with lipid peroxidation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:5

    Topics: Animals; Chlorobenzenes; Fatty Acids; Female; Free Radicals; Hexachlorobenzene; Lipid Peroxidation; Liver; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors; Uroporphyrinogen Decarboxylase

1989
The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity.
    Toxicology and applied pharmacology, 1989, Sep-15, Volume: 100, Issue:3

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme Inhibitors; Female; Hexachlorobenzene; Hydroquinones; In Vitro Techniques; Liver Diseases; Male; Microsomes, Liver; Oxidation-Reduction; Pentachlorophenol; Porphyrias; Rats; Rats, Inbred Strains; Troleandomycin

1989
The role of the Ah locus in hexachlorobenzene-induced porphyria. Studies in congenic C57BL/6J mice.
    The Biochemical journal, 1988, Aug-15, Volume: 254, Issue:1

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Genes; Hexachlorobenzene; Isoenzymes; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Uroporphyrinogen Decarboxylase

1988
Changes in some intestinal enzyme activities in experimental hexachlorobenzene-induced porphyria and modifying effects of diet.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; beta-Glucosidase; Chlorobenzenes; Diet; Dietary Carbohydrates; Disaccharidases; gamma-Glutamyltransferase; Hexachlorobenzene; Intestines; Male; Porphyrias; Rats; Rats, Inbred Strains

1986
Carcinogenicity of iron in conjunction with a chlorinated environmental chemical, hexachlorobenzene, in C57BL/10ScSn mice.
    International journal of cancer, 1989, Mar-15, Volume: 43, Issue:3

    Topics: Animals; Chlorobenzenes; Drug Synergism; Hexachlorobenzene; Hypertrophy; Iron; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Porphyrias

1989
Ability of several hexachlorobenzene metabolites to induce porphyrin accumulation in chick embryo liver "in ovo".
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1985, Volume: 35, Issue:4

    Topics: Animals; Chick Embryo; Chlorobenzenes; Hexachlorobenzene; Liver; Phenobarbital; Phenols; Porphyrias; Porphyrins; Sulfur

1985
The role of iron in the hexachlorobenzene induced porphyria. I. Studies on different types of iron and its relation with porphyrinogen carboxy-lyase decrease.
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1985, Volume: 35, Issue:4

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Disease Models, Animal; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase

1985
The role of contaminants in hexachlorobenzene toxicity.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 CYP1A1; Drug Contamination; Female; Hexachlorobenzene; Mice; Mice, Inbred Strains; Oxidoreductases; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug

1986
Neurotoxicity of hexachlorobenzene-induced porphyria turcica.
    IARC scientific publications, 1986, Issue:77

    Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Myotonia; Nervous System Diseases; Peripheral Nervous System Diseases; Porphyrias; Porphyrins

1986
Porphyria turcica: hexachlorobenzene-induced porphyria. Neurological manifestations and therapeutic trials of ethylenediaminetetracetic acid in the acute syndrome.
    IARC scientific publications, 1986, Issue:77

    Topics: Acute Disease; Chlorobenzenes; Edetic Acid; Hexachlorobenzene; Humans; Myotonia; Nervous System Diseases; Porphyrias; Syndrome; Thyroid Diseases

1986
Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: Aminolevulinic Acid; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Hexachlorobenzene; Levulinic Acids; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

1988
Investigations on the role of free radical processes in hexachlorobenzene-induced porphyria in mice.
    Journal of biochemical toxicology, 1988,Spring, Volume: 3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Free Radicals; Hexachlorobenzene; Iron; Lipid Peroxides; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Xanthine Oxidase

1988
Distinction between octachlorostyrene and hexachlorobenzene in their potentials to induce ethoxyphenoxazone deethylase and cause porphyria in rats and mice.
    Journal of biochemical toxicology, 1986, Volume: 1, Issue:1

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Porphyrias; Rats; Rats, Inbred F344; Styrenes; Uroporphyrinogen Decarboxylase

1986
[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene].
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1987, Volume: 37, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Deferoxamine; Hexachlorobenzene; Liver; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Remission Induction; Skin Diseases

1987
The effect of iron overload on the mitochondrial porphyrin level in the hexachlorobenzene induced experimental porphyria.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: Animals; Cell Membrane Permeability; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Liver; Mitochondria, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Valinomycin

1988
Alterations of uroporphyrinogen decarboxylase by chlorinated organics.
    Annals of the New York Academy of Sciences, 1987, Volume: 514

    Topics: Animals; Bromobenzenes; Carboxy-Lyases; Chlorobenzenes; Dioxins; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Sulfhydryl Reagents; Uroporphyrinogen Decarboxylase

1987
Turkish epidemic hexachlorobenzene porphyria. A 30-year study.
    Annals of the New York Academy of Sciences, 1987, Volume: 514

    Topics: Adolescent; Adult; Child; Child, Preschool; Chlorobenzenes; Disease Outbreaks; Female; Hexachlorobenzene; Humans; Male; Middle Aged; Porphyrias; Retrospective Studies

1987
Diet and alcohol effects on the manifestation of hepatic porphyrias.
    Federation proceedings, 1987, Volume: 46, Issue:5

    Topics: Alcohol Drinking; Bloodletting; Diabetes Mellitus; Diet; Hexachlorobenzene; Humans; Iron; Liver Diseases; Porphyrias; Porphyrins; Skin Diseases; Turkey

1987
[Toxicologic profile of hexachlorobenzene].
    Annali dell'Istituto superiore di sanita, 1987, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Environmental Exposure; Hexachlorobenzene; Humans; Immunity; Lethal Dose 50; Porphyrias; Tissue Distribution

1987
Liver porphyrinogen carboxylase in hexachlorobenzene porphyric rats. Studies with intermediate porphyrinogens of series III and with uroporphyrinogen I.
    The International journal of biochemistry, 1987, Volume: 19, Issue:4

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

1987
Experimental hepatic porphyria caused by hexachlorobenzene: mechanism of the metabolic block.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Hexachlorobenzene; Humans; Liver; Porphyrias; Uroporphyrinogen Decarboxylase

1986
Genetic, iron status and sex factors of porphyria induced by hexachlorobenzene.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Lipid Peroxides; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Sex Factors; Species Specificity; Uroporphyrinogen Decarboxylase

1986
Immunochemical studies of the uroporphyrinogen decarboxylase defect caused by hexachlorobenzene.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Ethylmaleimide; Female; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase

1986
Porphyrinogenic effect of hexachlorobenzene and 2,3,7,8-tetrachlorodibenzo-para-dioxin: is an inhibitor involved in uroporphyrinogen decarboxylase inactivation?
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Dioxins; Hexachlorobenzene; Kinetics; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Uroporphyrinogen Decarboxylase

1986
Porphyrins and pentachlorophenol in rat-liver mitochondria in hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Chlorophenols; Female; Hexachlorobenzene; Mitochondria, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1986
Hexachlorobenzene alteration of benzo[a]pyrene metabolism in porphyric and non-porphyric rats.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Benzo(a)pyrene; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred Strains

1986
Drug-induced uroporphyria in chicken hepatocyte cultures.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Cells, Cultured; Chickens; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Uroporphyrins

1986
Accumulation of uroporphyrin does not provoke further inhibition of liver uroporphyrinogen decarboxylase activity in hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrins

1986
Japanese quail as a model for the study of hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Coturnix; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hexachlorobenzene; Mice; Mice, Inbred C57BL; Porphyrias; Rats; Rats, Inbred Strains

1986
Does feeding of hexachlorobenzene promote structural changes in rat-liver porphyrinogen carboxy-lyase?
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Inbred Strains

1986
Rat-liver porphyrinogen carboxy-lyase inhibition as a function of the degree of hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Rats

1986
Studies on the role of iron in the alterations observed in hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Carboxy-Lyases; Chelating Agents; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Porphyrias; Rats; Rats, Inbred Strains

1986
Effect of an iron chelator on the onset of hexachlorobenzene-induced porphyria in rats.
    IARC scientific publications, 1986, Issue:77

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Enzyme Induction; Female; Hexachlorobenzene; Iron Chelating Agents; Porphyrias; Rats

1986
Effects of chloroquine and hydroxychloroquine on the hexachlorobenzene-induced porphyria in rats.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Chloroquine; Female; Hexachlorobenzene; Hydroxychloroquine; Porphyrias; Rats; Rats, Inbred Strains

1986
Induction of porphyria in cultured chick-embryo hepatocytes by halogenated aromatic compounds.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Cells, Cultured; Chick Embryo; Chlorobenzenes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hexachlorobenzene; Liver; Methylcholanthrene; Porphyrias; Uroporphyrins

1986
Introduction to the porphyrias.
    IARC scientific publications, 1986, Issue:77

    Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Porphyrias

1986
Porphyria turcica: hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Adult; Chlorobenzenes; Female; Hexachlorobenzene; Humans; Male; Middle Aged; Milk, Human; Porphyrias; Porphyrins

1986
The delay in polyhalogenated aromatic hydrocarbon-induced porphyria: mechanistic reality or methodological artefact?
    Toxicology letters, 1986, Volume: 31, Issue:3

    Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chromatography, High Pressure Liquid; Female; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1986
Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria.
    Biochemical pharmacology, 1986, Jul-15, Volume: 35, Issue:14

    Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Disease Models, Animal; Female; Hexachlorobenzene; Iron; Liver; Organ Size; Porphyrias; Porphyrins; Rats; Skin Diseases

1986
Lysosomes, but not mitochondria, accumulate iron and porphyrins in porphyria induced by hexachlorobenzene.
    The Biochemical journal, 1986, May-01, Volume: 235, Issue:3

    Topics: Animals; Centrifugation; Chelating Agents; Female; Hexachlorobenzene; Iron; Liver; Lysosomes; Mitochondria, Liver; Phenanthrolines; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1986
The delay in polyhalogenated aromatic hydrocarbon-induced porphyria: the effect of diet preparation.
    Toxicology letters, 1986, Volume: 32, Issue:3

    Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chromatography, High Pressure Liquid; Corn Oil; Female; Food; Hexachlorobenzene; Intestinal Absorption; Organ Size; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1986
Mechanistic studies of the inhibition of hepatic uroporphyrinogen decarboxylase in C57BL/10 mice by iron-hexachlorobenzene synergism.
    The Biochemical journal, 1986, Sep-15, Volume: 238, Issue:3

    Topics: Alanine Transaminase; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytosol; Drug Synergism; Hexachlorobenzene; Iron; Lipid Metabolism; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oxidoreductases; Porphyrias; Species Specificity; Uroporphyrinogen Decarboxylase; Uroporphyrins

1986
Influence of chloroquine on the porphyrin metabolism.
    Archives of dermatological research, 1985, Volume: 277, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Chloroquine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Hexachlorobenzene; Microsomes, Liver; Oxygenases; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains

1985
Hexachlorobenzene-induced porphyria in Japanese quail: an in vitro study of changes in cytochrome P-450 and monooxygenases.
    Journal of toxicology and environmental health, 1985, Volume: 16, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxygenases; Porphyrias; Proadifen

1985
Influence of (+)-propoxyphene on the hexachlorobenzene-induced porphyria of rats.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:11

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Chlorobenzenes; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Female; Hexachlorobenzene; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Porphyrias; Rats; Rats, Inbred Strains; Time Factors

1985
Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria.
    Toxicology letters, 1986, Volume: 30, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Enzyme Induction; Female; Hexachlorobenzene; Liver Diseases; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine

1986
The involvement of iron and lipid peroxidation in the pathogenesis of HCB induced porphyria.
    Biochemical pharmacology, 1985, Jan-15, Volume: 34, Issue:2

    Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Lipid Peroxides; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase

1985
The effect of tetrachlorohydroquinone on hexachlorobenzene-induced porphyria in Japanese quail.
    Journal of toxicology and environmental health, 1985, Volume: 15, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Coturnix; Drug Interactions; Female; Hexachlorobenzene; Hydroquinones; Lactose; Liver; Liver Diseases; Organ Size; Porphyrias; Porphyrins

1985
A comparison of the effects of hexachlorobenzene, beta-naphthoflavone, and phenobarbital on cytochrome P-450 and mixed-function oxidases in Japanese quail.
    Journal of toxicology and environmental health, 1985, Volume: 15, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Coturnix; Electrophoresis, Polyacrylamide Gel; Female; Flavonoids; Hexachlorobenzene; Injections, Intraperitoneal; Liver Diseases; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxygenases; Phenobarbital; Porphyrias

1985
Hepatocarcinogenicity of hexachlorobenzene in rats and the sex difference in hepatic iron status and development of porphyria.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Animals; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Kidney; Liver; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred F344; Sex Factors; Uroporphyrinogen Decarboxylase

1985
The role of pentachlorophenol in causing mitochondrial derangement in hexachlorobenzene induced experimental porphyria.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Female; Hexachlorobenzene; Liver; Liver Diseases; Membrane Potentials; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Uncoupling Agents

1985
Influence of N-acetylcysteine on the hexachlorobenzene induced porphyria in rats.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Acetylcysteine; Animals; Chlorobenzenes; Female; Glutathione; Hexachlorobenzene; Liver; Mixed Function Oxygenases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors

1985
Hexachlorobenzene-induced porphyria in Japanese quail: changes in microsomal enzymes.
    Journal of toxicology and environmental health, 1985, Volume: 15, Issue:3-4

    Topics: Animals; Chlorobenzenes; Coturnix; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glutathione Transferase; Hexachlorobenzene; Microsomes, Liver; Porphyrias; Porphyrins; Proteins

1985
Fate of hexachlorobenzene in C57BL/10 mice with iron overload.
    Biochemical pharmacology, 1985, Dec-01, Volume: 34, Issue:23

    Topics: Animals; Carbon Radioisotopes; Chlorobenzenes; Hexachlorobenzene; Iron; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Porphyrias; Species Specificity; Tissue Distribution

1985