hexachlorobenzene has been researched along with Porphyrias in 175 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 134 (76.57) | 18.7374 |
1990's | 34 (19.43) | 18.2507 |
2000's | 7 (4.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Aldonatti, C; Llambías, EB; San Martín de Viale, LC | 1 |
OCKNER, RK; SCHMID, R | 1 |
GAJDOS, A; GAJDOS-TOROK, M | 1 |
CAN, C; NIGOGOSYAN, G | 1 |
BURNETT, JW; PATHAK, MA | 1 |
CAMPBELL, JA | 1 |
MALKINSON, FD; PEARSON, RW | 1 |
de Viale, LC; Lelli, SM; Mazzetti, MB; Taira, MC | 1 |
Cárdenas, ML; Chaufan, G; Corvi, MM; Ríos de Molina, Mdel C; San Martín de Viale, LC | 1 |
Gerhard, GS; Gorman, N; Robinson, SW; Sinclair, JF; Sinclair, PR; Smith, AG; Trask, HS | 1 |
Adzharov, D; Chernev, K; Ivanov, E | 1 |
Miura, T; Tagami, H; Torinuki, W | 1 |
Billi, SC; Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
Debets, FM; Hamers, WJ; Strik, JJ | 1 |
Horváth, LI; Kiss, M; Kószó, F; Siklósi, C; Simon, N | 1 |
Bender, RC; Buhler, DR; Carpenter, HM; Henderson, MC; Williams, DE | 1 |
Cripps, DJ; Dogramici, I; Gocmen, A; Peters, HA | 1 |
Ceccarelli-Stanzani, D; Masini, A; Rocchi, E; Trenti, T; Ventura, E | 1 |
Ríos de Molina, MC; San Martin de Viale, LC; Taira de Yamasato, MC; Tomio, JM; Wainstok de Calmanovici, R | 1 |
Pimstone, NR | 1 |
Herbert, M; Ippen, H; Koransky, W; Koss, G; Seubert, A; Seubert, S | 1 |
Cole, SP; Marks, GS; Zelt, DT | 1 |
Ippen, H; Koransky, W; Koss, G; Seidel, J; Seubert, A; Seubert, S | 1 |
Bolsen, K; Goerz, G; Landmann, H; Teschke, R | 1 |
Bjørndal, T; Høvding, G; Romslo, I; Sandberg, S | 1 |
Goerz, G; Krieg, T; Lissner, R; Sick, N; Vizethum, W | 1 |
Day, RS; Disler, PB; Eales, L | 1 |
Bolsen, K; Goerz, G; Thier, W | 1 |
Catalán Beltrán, T; Chinarro Familiar, S; Enríquez de Salamanca, R; Mas Andrés, V; Molina Ferragut, C; Olmos Andrés, A | 1 |
Bryan, GT; Cripps, DJ; Dogramaci, I; Gocmen, A; Peters, HA | 1 |
Golf, SW; Graef, V; Tyrell, C | 1 |
Elder, GH; Sheppard, DM | 1 |
Siegers, CP | 1 |
Meyer, HD; Richter, E; Schäfer, SG | 1 |
Bańkowska, J | 2 |
Rizzardini, M; Smith, AG | 1 |
Bolsen, K; Goerz, G; Lissner, R; Staib, AH | 1 |
Debets, AJ; Debets, FM; Koss, G; Lössbroek, TG; Reinders, JH; Strik, JJ | 1 |
Kószó, F; Siklósi, C; Simon, N | 2 |
Kumai, N; Miura, T; Torinuki, W | 1 |
Cripps, DJ; Gocmen, A; Peters, HA | 1 |
Francis, JE; Smith, AG | 1 |
Bolsen, K; Goerz, G; Simon, K; Vizethum, W; Weber, K | 1 |
Doss, M; Koss, G; von Tiepermann, R | 1 |
De Matteis, F; Francis, JE; Smith, AG | 1 |
Blekkenhorst, GH; Day, RS; Eales, L | 2 |
Debets, FM; Olie, K; Strik, JJ | 1 |
Irifune, H; Tanaka, K; Yoshida, H | 1 |
Bloksma, N; Den Besten, C; Schielen, P; Seinen, W; Van Bladeren, PJ; Vos, JG | 1 |
Carthew, P; Francis, JE; Ingebrigtsen, K; Smith, AG | 1 |
Billi de Catabbi, SC; San Martin de Viale, LC | 1 |
Ferramola de Sancovich, AM; Kleiman de Pisarev, DL; Sancovich, HA; Sopena de Kracoff, YE | 1 |
Cleton-Soeteman, MI; de Bruijn, WC; Siersema, PD; ten Kate, FJ; van Eijk, HG; Wilson, JH | 1 |
Cabral, JR; Carthew, P; Francis, JE; Manson, MM; Smith, AG | 2 |
Bartlett, S; Franklin, C; Jarrell, JF; McMahon, A; Singh, A; Valli, VE; Villeneuve, D | 1 |
Bennik, MH; Brouwer, A; Bruggeman, I; den Besten, C; Koeman, JH; Kuper, F; Schielen, P; Van Bladeren, PJ; Vos, JG | 1 |
Den Besten, C; Haas, J; Rietjens, IM; Steensma, A; van Bladeren, PJ; van Ommen, B; van Tintelen, G | 1 |
Barnstorf, W; Bolsen, K; Fritsch, C; Goerz, G; Kalka, K; Tsambaos, D; Winnekendonk, G | 1 |
Aldonatti, C; Billi de Catabbi, S; Fernandez, MC; Minutolo, C; San Martín de Viale, L; Sterin-Speziale, N | 1 |
Almeida, MG; Aznar, AE; Barros, SB; Davino, SC; Fanini, F; Koch, OR | 1 |
Charbonneau, M; Cooper, SF; Legault, N; Sabik, H | 1 |
Chlumská, A; Fakan, F; Krijt, J; Michal, M; Safanda, J | 1 |
Aldonatti, C; Ríos de Molina, MC; San Martín de Viale, LC; Vilas, GL | 1 |
Aldonatti, C; de Calmanovici, RW; de Catabbi, SB; Minutolo, C; San Martin de Viale, LC | 1 |
Aldonatti, C; Billi de Catabbi, SC; Fernández-Tomé, MC; San Martin de Viale, LC; Sterin-Speziale, NB | 1 |
Aldonatti, C; de Viale, LC | 1 |
Billi de Catabbi, SC; Cochón, AC; San Martín de Viale, LC | 1 |
Adjarov, D; Apostolov, I; Chernev, K; Dimitrov, P; Drenska, E; Ivanov, E; Krustev, L; Pramatarova, V; Stefanova, M | 1 |
Elder, GH; Evans, N; Ferramola, AM; Games, DE; Jackson, AH; Matlin, SA; Sancovich, HA; Smith, SG | 1 |
Hazelrigg, D; Jarratt, M | 1 |
Bergman, H; Friesen, M; Goldstein, JA; Hass, JR; Hickman, P; Scotti, TM | 1 |
Courtney, KD | 1 |
Muhlbauer, JE; Pathak, MA | 1 |
Benedetto, AV; Taylor, JS | 1 |
Goerz, G; Tsambaos, D; Vizethum, W | 1 |
Cabral, JR; De Matteis, F; Smith, AG | 1 |
Carlson, GP | 1 |
De Calmanovici, RW; Ríos De Molina, MD; San Martín De Viale, LC; Tomio, JM | 1 |
Bolsen, K; Goerz, G; Krieg, T; Lissner, R; Vizethum, W | 1 |
Blekkenhorst, GH; Eales, L | 1 |
Cooper, P | 1 |
Peters, HA | 1 |
Grinstein, M | 1 |
Baker, JR; Esber, H; Fleischman, RW; Gralla, EJ; Hagopian, M; Luthra, YK; Marcus, W | 1 |
Carstens, M; Louw, M; Neethling, AC; Percy, VA; Shanley, BC | 1 |
Blekkenhorst, GH; Eales, L; Pimstone, NR; Webber, BL | 1 |
Doss, M; Koss, G; Schermuly, E | 1 |
Eichenauer, MG; Goerz, G; Ippen, H; Lissner, R | 1 |
Grant, DL; Shields, JB; Villeneuve, DC | 1 |
Doyle, M; Jones, K; Magnus, IA; Miura, T | 1 |
Brodeur, J; Charbonneau, M; Krishnan, K; Plaa, GL | 1 |
Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R; Zenklusen, JC | 1 |
Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
Brodeur, J; Charbonneau, M; Krishnan, K | 1 |
Billi de Catabbi, S; Ríos de Molina, MC; San Martín de Viale, LC | 2 |
Bolsen, K; Goerz, G; Jugert, F; Lehmann, P; Merk, HF; Schaefer, T; Scharffetter, K | 1 |
Cleton, MI; de Bruijn, WC; Ketelaars, DA; Siersema, PD; van Eijk, HG; van Helvoirt, RP; Wilson, JH | 1 |
Cantoni, L; Cuomo, R; De Rosa, G; Di Padova, C; Le Grazie, C; Rizzardini, M; Rizzoli, R; Roda, E; Rodino, S; Simoni, P | 1 |
Adjarov, DG | 1 |
Francis, JE; Green, JA; Greig, JB; Manson, MM; Smith, AG; Wolf, CR | 1 |
Aldonatti, C; Bergoc, R; Cochón, AC; San Martín de Viala, LC; Wainstok de Calmanovici, R | 1 |
Conde, C; Enriquez de Salamanca, R; Lopez-Miras, A; Munoz, JJ; To-Figueras, J | 1 |
Budillon, G; Cantoni, L; Cuomo, R; Di Padova, C; Le Grazie, C; Rizzardini, M; Rodinò, S | 1 |
Kleiman de Pisarev, DL; Rios de Molina, MC; San Martin de Viale, LC | 1 |
Adzharov, D | 1 |
Kennedy, SW; Wigfield, DC | 2 |
Bryan, GT; Cripps, DJ; Gocmen, A; Morris, CR; Peters, HA | 2 |
Francis, JE; Green, JA; Manson, MM; Smith, AG; Wolf, CR | 1 |
Bacon, BR; Feldman, ES | 1 |
Muller-Eberhard, U; Smith, AG; Vincent, SH | 1 |
Cabral, JR; Manson, MM; Smith, AG; Stewart, FP | 1 |
Rios de Molina, MC; San Martin de Viale, LC; Taira, MC | 1 |
Aldonatti, CA; Billi de Catabbi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
Edixhoven-Bosdijk, A; Koole-Lesuis, R; Rietveld, T; van den Berg, JW; Visser, O; Wilson, JH | 1 |
Bessems, JG; Geesink, G; Hendriks, W; Müller, F; van Bladeren, PJ; van Ommen, B | 1 |
Gasiewicz, TA; Goldstein, JA; Hahn, ME; Linko, P | 1 |
Adjarov, D; Ivanov, E; Savov, G | 1 |
Billi, SC; San Martín de Viale, LC | 1 |
Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 2 |
Basford, D; Krestynski, F; Sweeney, GD | 1 |
Bryan, GT; Cripps, DJ; Ertürk, E; Gocmen, A; Morris, CR; Peters, HA | 1 |
De Matteis, F | 2 |
Bement, WJ; Elder, GH; Gorman, N; Lambrecht, RW; Roberts, AG; Sinclair, JA; Sinclair, PR; Urquhart, AJ | 1 |
Cantoni, L; Carugo, C; Graziani, A; Rizzardini, M | 1 |
Bird, I; Francis, JE; Smith, AG | 1 |
Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 2 |
Strik, JJ | 1 |
Axelson, O | 1 |
Ceccarelli, D; Masini, A; Muscatello, U; Trenti, T | 1 |
Elder, GH; Roberts, AG; Urquhart, AJ | 1 |
Bryan, G; Cripps, D; Ertürk, E; Göcmen, A; Morris, C; Peters, H | 1 |
Sweeney, GD | 1 |
Cripps, DJ | 1 |
Jori, A | 1 |
Francis, JE; Smith, AG; Stewart, FP | 1 |
Elder, GH; Urquhart, AJ | 1 |
Cantoni, L; Graziani, A; Rizzardini, M; Saletti, MC | 1 |
Ceccarelli, D; Masini, A; Trenti, T; Ventura, E | 1 |
Bolsen, K; Goerz, G; Lissner, R; Merk, H | 1 |
De Matteis, F; Ferioli, A; Harvey, C | 1 |
Adjarov, DG; Elder, GH | 1 |
Buhler, DR; Carpenter, HM | 1 |
Billi, SC; Ríos de Molina, Mdel C; San Martín de Viale, LC | 1 |
Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
Ríos de Molina, Mdel C; San Martín de Viale, LC; Vila, MC; Wainstok de Calmanovici, R | 1 |
Bolsen, K; Goerz, G; Lissner, R; Merk, H; Schmitter, H; Seuwen, P | 1 |
Bement, WJ; Bonkovsky, HL; Lambrecht, RW; Sinclair, JF; Sinclair, PR | 1 |
Elder, GH | 1 |
Cripps, DJ; Dogramaci, I; Gocmen, A; Morris, CR; Peters, HA | 1 |
Fox, GA; Kennedy, SW; Wigfield, DC | 1 |
Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R | 1 |
Tangerås, A | 1 |
Francis, JE; Greig, JB; Kay, SJ; Smith, AG; Stewart, FP | 1 |
Bolsen, K; Goerz, G; Merk, H | 1 |
Buhler, DR; Carpenter, HM; Williams, DE | 3 |
Bolsen, K; Goerz, G; Merk, H; von Zittwitz, A | 1 |
Gorski, JR; Parkinson, A; Rozman, K; Rozman, P | 1 |
Alleman, MA; Edixhoven-Bosdijk, A; Koster, JF; Kroos, MJ; Slee, RG; von Eijk, HG; Wilson, JH | 1 |
Buhler, DR; Carpenter, HM; Harvey, MJ | 1 |
Cabral, JR; Dinsdale, D; Francis, JE; Manson, MM; Smith, AG | 1 |
Ceccarelli-Stanzani, D; Masini, A; Tomasi, A; Trenti, T; Ventura, E | 1 |
Bolsen, K; Brunner, W; Goerz, G; Lissner, R; Merk, H | 1 |
Khanna, RN; Smith, AG | 1 |
12 review(s) available for hexachlorobenzene and Porphyrias
Article | Year |
---|---|
Porphyria cutanea tarda.
Topics: Age Factors; Animals; Disease Models, Animal; Erythropoiesis; Heme; Hexachlorobenzene; Humans; Hydrocarbons, Halogenated; Iron; Kidney Failure, Chronic; Liver; Photosensitivity Disorders; Porphyrias; Renal Dialysis; Skin Diseases; Skin Pigmentation; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1982 |
Porphyrias and the kidney.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coproporphyrinogens; Coproporphyrins; Hexachlorobenzene; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Lead Poisoning; Porphyrias; Rats; Renal Dialysis; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1981 |
[Experimental porphyria].
Topics: Animals; Disease Models, Animal; Griseofulvin; Hexachlorobenzene; Humans; Mice; Polychlorinated Biphenyls; Porphyrias | 1995 |
Hexachlorobenzene (HCB): a review.
Topics: Animals; Birds; Chlorobenzenes; Cricetinae; Dogs; Environmental Exposure; Female; Fishes; Food Contamination; Guinea Pigs; Haplorhini; Hexachlorobenzene; Liver; Macaca; Maternal-Fetal Exchange; Mice; Porphyrias; Pregnancy; Rabbits; Sheep; Skin Diseases; Soil Pollutants; Swine; Teratogens | 1979 |
Porphyria cutanea tarda.
Topics: Adolescent; Aged; Alcoholism; Animals; Chick Embryo; Child; Chloroquine; Diagnosis, Differential; Hexachlorobenzene; Humans; Iron; Kidney Neoplasms; Liver Neoplasms; Middle Aged; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases | 1979 |
Porphyria cutanea tarda. Update 1978.
Topics: Anti-Bacterial Agents; Antimalarials; Estrogens; Hexachlorobenzene; Humans; Liver Neoplasms; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Porphyrias; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1978 |
More light on hexachlorobenzene.
Topics: Animals; Chlorobenzenes; Dose-Response Relationship, Drug; Environmental Exposure; Erythrocytes; Female; Fetus; Hexachlorobenzene; Humans; Liver; Male; Occupational Medicine; Pesticide Residues; Porphyrias; Pregnancy; Sex Factors; Species Specificity | 1976 |
Hexachlorobenzene poisoning in Turkey.
Topics: Adolescent; Chlorobenzenes; Edetic Acid; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Infant; Male; Porphyrias; Turkey | 1976 |
Toxicological aspects of liver heme biosynthesis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; Hexachlorobenzene; Liver; Porphyrias; Protoporphyrins; Rats; Rats, Gunn | 1988 |
Subacute toxicity of hexachlorobenzene.
Topics: Animals; Bile; Cats; Chlorobenzenes; Coturnix; Guinea Pigs; Hexachlorobenzene; Liver; Mice; Porphyrias; Rabbits; Rats; Swine | 1986 |
A review of porphyria and cancer and the missing link with human exposure to hexachlorobenzene.
Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Liver Cirrhosis; Liver Neoplasms; Lymphoma; Neoplasms; Porphyrias; Sarcoma; Skin Diseases | 1986 |
Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases.
Topics: Animals; Bloodletting; Carboxy-Lyases; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Heme; Hexachlorobenzene; Humans; Hydroxamic Acids; Iron; Lead Poisoning; Male; Mice; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases; Uroporphyrinogen Decarboxylase | 1986 |
163 other study(ies) available for hexachlorobenzene and Porphyrias
Article | Year |
---|---|
Tryptophan metabolism via serotonin in rats with hexachlorobenzene experimental porphyria.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, High Pressure Liquid; Digestive System; Disease Models, Animal; Fungicides, Industrial; Hexachlorobenzene; Humans; Liver; Porphyria Cutanea Tarda; Porphyrias; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2003 |
Acquired porphyria in man and rat due to hexachlorobenzene intoxication.
Topics: Animals; Benzene Derivatives; Hexachlorobenzene; Humans; Male; Porifera; Porphyrias; Rats | 1961 |
[Experimental porphyria in the white rat induced by hexachlorobenzene. Therapeutic action of adenosine-5-monophosphoric acid].
Topics: Adenine Nucleotides; Adenosine; Animals; Hexachlorobenzene; Hexachlorocyclohexane; Porifera; Porphyrias; Rats | 1961 |
Acquired toxic porphyria cutanea tarda due to hexachlorobenzene. Report of 348 cases caused by this fungicide.
Topics: Antifungal Agents; Cyclohexanes; Hexachlorobenzene; Humans; Porphyria Cutanea Tarda; Porphyrias | 1963 |
EFFECT OF LIGHT UPON PORPHYRIN METABOLISM OF RATS. STUDY OF PORPHYRIN METABOLISM OF NORMAL RATS AND RATS WITH HEXACHLOROBENZENE-INDUCED PORPHYRIA.
Topics: Hexachlorobenzene; Hexachlorocyclohexane; Humans; Light; Liver; Metabolism; Porphyrias; Porphyrins; Rats; Research; Ultraviolet Rays; Urine | 1964 |
PATHOLOGICAL ASPECTS OF HEXACHLOROBENZENE FEEDING IN RATS.
Topics: Erythrocytes; Fluorescence; Hexachlorobenzene; Hexachlorocyclohexane; Histocytochemistry; Lipids; Liver; Pathology; Pigments, Biological; Porphyrias; Rats; Research; Toxicology | 1963 |
SOME OBSERVATIONS ON HEXACHLOROBENZENE INDUCED EXPERIMENTAL PORPHYRIA.
Topics: Alcohols; Animals; Blister; Dentin; Dermatitis, Phototoxic; Ethanol; Fluorescence; Guinea Pigs; Hair; Hexachlorobenzene; Hexachlorocyclohexane; Microscopy; Microscopy, Fluorescence; Pathology; Pharmacology; Photosensitivity Disorders; Porphyrias; Porphyrins; Rats; Research; Skin; Tooth; Toxicology; Ultraviolet Rays; Urine | 1965 |
Glycogen metabolism and glucose transport in experimental porphyria.
Topics: Animals; Disease Models, Animal; Female; Fungicides, Industrial; Gluconeogenesis; Glucose; Glycogen; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar | 2004 |
Abnormal kinetic behavior of uroporphyrinogen decarboxylase obtained from rats with hexachlorobenzene-induced porphyria.
Topics: Animals; Female; Hexachlorobenzene; Kinetics; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 2005 |
Hexachlorobenzene stimulates uroporphyria in low affinity AHR mice without increasing CYP1A2.
Topics: Animals; Cytochrome P-450 CYP1A2; Female; Hemochromatosis Protein; Hexachlorobenzene; Histocompatibility Antigens Class I; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mutation; Porphyrias; Receptors, Aryl Hydrocarbon; Sex Factors; Uroporphyrins | 2007 |
[Induction of mixed microsomal oxidase in experimental hexachlorobenzene porphyria in rabbits].
Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; gamma-Glutamyltransferase; Hexachlorobenzene; Microsomes, Liver; Oxidoreductases; Porphyrias; Rabbits; Skin Diseases | 1981 |
Activation of the alternative complement pathway by 405 nm light in serum from porphyric rat.
Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement Activation; Complement Pathway, Alternative; Female; Hexachlorobenzene; Neutrophils; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases; Ultraviolet Rays | 1984 |
[Experimental porphyria induced by chlorinated hydrocarbons. Studies of porphyrinogen carboxy-lyase in the experimental model of human cutaneous delayed porphyria].
Topics: Animals; Carboxy-Lyases; Disease Models, Animal; Female; Hexachlorobenzene; Hot Temperature; Liver; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases | 1984 |
Metabolism as a prerequisite for the porphyrinogenic action of polyhalogenated aromatics, with special reference to hexachlorobenzene and polybrominated biphenyls (Firemaster BP-6).
Topics: 5-Aminolevulinate Synthetase; Animals; Biotransformation; Biphenyl Compounds; Cells, Cultured; Chick Embryo; Chlorobenzenes; Enzyme Induction; Heme; Hexachlorobenzene; Liver; Polybrominated Biphenyls; Porphyrias; Porphyrins; Spectrometry, Fluorescence | 1980 |
The role of possible membrane damage in porphyria cutanea tarda: a spin label study of rat liver cell membranes.
Topics: Animals; Cell Membrane; Cell Separation; Electron Spin Resonance Spectroscopy; Ethanol; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Skin Diseases; Spin Labels | 1982 |
Hexachlorobenzene-induced porphyria in Japanese quail. Effect of pretreatment with phenobarbital or beta-naphthoflavone.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Flavonoids; Glutathione Transferase; Hexachlorobenzene; Liver; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Phenobarbital; Porphyrias | 1984 |
Porphyria turcica due to hexachlorobenzene: a 20 to 30 year follow-up study on 204 patients.
Topics: Adult; Chlorobenzenes; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Male; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey | 1984 |
Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria.
Topics: Animals; Female; Hexachlorobenzene; Iron; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1984 |
Mechanism of hexachlorobenzene-induced porphyria in rats. Effect of phenobarbitone pretreatment.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Ferrochelatase; Hexachlorobenzene; Hydroxymethylbilane Synthase; Liver; Organ Size; Phenobarbital; Porphobilinogen Synthase; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1984 |
Hexachlorobenzene and 2, 4, 5, 2; 4; 5'-hexachlorobiphenyl - a comparison of their distribution, biotransformation and porphyrinogenic action in female rats.
Topics: Animals; Biotransformation; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Polychlorinated Biphenyls; Porphyrias; Porphyrins; Rats; Tissue Distribution | 1980 |
Alterations in the heme biosynthetic pathway as an index of exposure to toxins.
Topics: Cytochrome P-450 Enzyme System; Environmental Pollutants; Heme; Hexachlorobenzene; Hydrocarbons, Chlorinated; Lead; Polychlorinated Biphenyls; Porphyrias; Porphyrins | 1982 |
Studies on the toxicology of hexachlorobenzene. V. Different phases of porphyria during and after treatment.
Topics: Animals; Chlorobenzenes; Cytosol; Female; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors; Uroporphyrinogen Decarboxylase | 1983 |
Effect of hexachlorobenzene on the activities of hepatic alcohol metabolizing enzymes.
Topics: Animals; Chlorobenzenes; Disease Models, Animal; Ethanol; Female; Hexachlorobenzene; Liver; Liver Diseases; Porphyrias; Rats; Rats, Inbred Strains | 1983 |
Porphyrin-induced photodamage as related to the subcellular localization of the porphyrins.
Topics: Animals; Female; Griseofulvin; Hexachlorobenzene; Humans; Liver; Lysosomes; Male; Middle Aged; Mitochondria, Liver; Photosensitivity Disorders; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Skin Diseases | 1982 |
[Influence of p-amino-benzoic acid on the hexachlorobenzene induced porphyria in the rat (author's transl)].
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Aminolevulinic Acid; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Glycine; Hexachlorobenzene; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1980 |
[Influence of silymarin and (+)-cyanidanol-3 on the HCB-induced porphyria in rats (author's transl)].
Topics: Animals; Benzopyrans; Catechin; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Flavins; Flavonoids; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Silymarin | 1982 |
[Induction of experimental porphyria by hexachlorobenzene in rats].
Topics: Animals; Chlorobenzenes; Disease Models, Animal; Female; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Rats, Inbred Strains; Skin Diseases | 1982 |
Epidemiology of hexachlorobenzene-induced porphyria in Turkey: clinical and laboratory follow-up after 25 years.
Topics: Adult; Chlorobenzenes; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Male; Maternal-Fetal Exchange; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey | 1982 |
Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene.
Topics: Animals; Chlorobenzenes; Etiocholanolone; Female; Flutamide; Hexachlorobenzene; Liver; Oxidoreductases; Porphyrias; Porphyrins; Rats; Stereoisomerism; Steroids | 1982 |
Immunoreactive uroporphyrinogen decarboxylase is unchanged in porphyria caused by TCDD and hexachlorobenzene.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Dioxins; Disease Models, Animal; Hexachlorobenzene; Immune Sera; Immunoelectrophoresis, Two-Dimensional; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1982 |
[Effect of silymarin and (+)-cyanidanol-3 on hexachlorobenzene(HCB)-induced porphyria in rats].
Topics: Animals; Benzopyrans; Catechin; Chlorobenzenes; Disease Models, Animal; Flavonoids; Hexachlorobenzene; Liver Diseases; Porphyrias; Rats; Research Design; Silymarin | 1982 |
Iron absorption during the development of hexachlorobenzene-induced porphyria in rats.
Topics: Acute Disease; Animals; Female; Hexachlorobenzene; Intestinal Absorption; Iron; Jejunum; Liver; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Skin Diseases | 1982 |
[Hepatotoxicity of selected polychlorinated aromatic hydrocarbons].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Dioxins; Hexachlorobenzene; Liver; Pentachlorophenol; Polychlorinated Dibenzodioxins; Porphyrias; Rats | 1982 |
Sex differences in the metabolism of hexachlorobenzene by rats and the development of porphyria in females.
Topics: Animals; Bile; Chlorobenzenes; Diethylstilbestrol; Female; Hexachlorobenzene; Liver; Male; Pentachlorophenol; Phenols; Porphyrias; Rats; Rats, Inbred F344; Sex Factors; Time Factors | 1982 |
[Influence of theophylline on hexachlorobenzene induced porphyria (author's transl)].
Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Hexachlorobenzene; Liver; Mixed Function Oxygenases; Organ Size; Porphyrias; Proteins; Rats; Rats, Inbred Strains; Theophylline | 1981 |
Biotransformation and porphyringogenic action of hexachlorobenzene and its metabolites in a primary liver cell culture.
Topics: Animals; Biotransformation; Cells, Cultured; Chick Embryo; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase | 1981 |
[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)].
Topics: Animals; Chloranil; Chlorobenzenes; Hexachlorobenzene; Pentachlorophenol; Porphyrias; Porphyrins; Rats | 1981 |
Histopathological studies on sun-exposed hexachlorobenzene-induced porphyric rat skin.
Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred Strains; Skin; Sunlight | 1981 |
Porphyria turcica. Twenty years after hexachlorobenzene intoxication.
Topics: Adipose Tissue; Adolescent; Adult; Child; Child, Preschool; Chlorobenzenes; Female; Follow-Up Studies; Food Contamination; Hexachlorobenzene; Humans; Infant; Infant, Newborn; Male; Middle Aged; Milk, Human; Porphyrias; Porphyrins; Pregnancy; Skin Diseases; Turkey | 1980 |
Relative abilities on a molar basis of hexafluoro-, hexachloro- and hexabromobenzenes to decrease liver uroporphyrinogen decarboxylase activity and cause porphyria in female rats.
Topics: Animals; Body Weight; Bromobenzenes; Carboxy-Lyases; Chlorobenzenes; Diet; Enzyme Induction; Female; Fluorocarbons; Hexachlorobenzene; Liver; Organ Size; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1980 |
[Influence of chloroquine on the hexachlorobenzene-induced porphyria. Investigations in the skin, liver, and urine (author's transl)].
Topics: Animals; Chloroquine; Female; Hexachlorobenzene; Iron; Liver; Porphyrias; Porphyrins; Rats; Skin | 1980 |
Uroporphyrinogen decarboxylase deficiency in experimental chronic hepatic porphyria.
Topics: Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Erythrocytes; Female; Hexachlorobenzene; Liver; Liver Diseases; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1980 |
Lobes of rat liver respond at different rates to challenge by dietary hexachlorobenzene.
Topics: Animals; Chlorobenzenes; Female; Glutathione; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase | 1980 |
Drug induced acute porphyric episodes in rats.
Topics: Animals; Feces; Female; Hexachlorobenzene; Intestinal Mucosa; Kidney; Kinetics; Liver; Male; Phenylbutazone; Porphyrias; Porphyrins; Rats | 1980 |
The effect of bleeding and iron administration on the development of hexachlorobenzene-induced rat porphyria.
Topics: Animals; Blood; Colon; Female; Hexachlorobenzene; Iron; Kidney; Liver; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase | 1980 |
Effects of pentachlorophenol on rat liver changes induced by hexachlorobenzene, with special reference to porphyria, and alterations in mixed function oxygenases.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Female; Gas Chromatography-Mass Spectrometry; Hexachlorobenzene; Liver; Microsomes, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats | 1980 |
Immune effects of hexachlorobenzene in the rat: role of metabolism in a 13-week feeding study.
Topics: Adjuvants, Immunologic; Animals; Antibody Specificity; Autoantigens; Biotransformation; Body Weight; Female; Hexachlorobenzene; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lymphatic Diseases; Lymphoid Tissue; Organ Size; Porphyrias; Rats; Rats, Wistar; Skin; Skin Diseases; Splenomegaly; Troleandomycin | 1995 |
Influence of iron on the induction of hepatic tumors and porphyria by octachlorostyrene in C57BL/10ScSn mice.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Environmental Pollutants; Hexachlorobenzene; Iron; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Porphyrias; Styrenes | 1994 |
Studies on the active centre(s) of rat liver porphyrinogen carboxy-lyase. In vivo effect of hexachlorobenzene on decarboxylation site(s) of porphyrinogens.
Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Decarboxylation; Diacetyl; Female; Hexachlorobenzene; Histidine; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar | 1994 |
Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria.
Topics: Animals; Carboxy-Lyases; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Wistar; Thyroidectomy; Thyroxine; Triiodothyronine | 1994 |
Ferritin accumulation and uroporphyrin crystal formation in hepatocytes of C57BL/10 mice: a time-course study.
Topics: Animals; Crystallization; Drug Synergism; Ferritins; Hexachlorobenzene; Iron-Dextran Complex; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Porphyrias; Time Factors; Uroporphyrins | 1993 |
Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene.
Topics: Animals; Carcinogens; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glutathione Transferase; Hexachlorobenzene; Iron; Liver; Liver Neoplasms; Porphyrias; Rats; Rats, Inbred F344 | 1993 |
Hexachlorobenzene toxicity in the monkey primordial germ cell without induced porphyria.
Topics: Animals; Female; Fertilization in Vitro; Germ Cells; Hexachlorobenzene; Liver; Liver Function Tests; Macaca fascicularis; Oocytes; Ovarian Follicle; Porphyrias; Porphyrins; Pregnancy; Tissue Distribution | 1993 |
The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study.
Topics: Animals; Biotransformation; Body Weight; Chlorobenzenes; Eating; Female; Hexachlorobenzene; Homeostasis; Liver; Organ Size; Oxidation-Reduction; Phencyclidine; Porphyrias; Porphyrins; Rats; Rats, Wistar; Retinoids; Thyroid Hormones; Troleandomycin | 1993 |
Comparative biotransformation of hexachlorobenzene and hexafluorobenzene in relation to the induction of porphyria.
Topics: Animals; Biotransformation; Female; Fluorocarbons; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar | 1995 |
Influence of UVA and UVB irradiation on hepatic and cutaneous P450 isoenzymes.
Topics: Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glutathione; Hexachlorobenzene; Humans; Isoenzymes; Liver; Oxidoreductases, N-Demethylating; Porphyrias; Rats; Rats, Wistar; Skin; Ultraviolet Rays | 1996 |
Time course of hexachlorobenzene-induced alterations of lipid metabolism and their relation to porphyria.
Topics: Animals; Female; Fungicides, Industrial; Hexachlorobenzene; Lipid Metabolism; Lipid Peroxidation; Porphyrias; Rats; Rats, Wistar | 1997 |
Pro- and anti-oxidant parameters in rat liver after short-term exposure to hexachlorobenzene.
Topics: Animals; Coproporphyrins; Cytochrome P-450 Enzyme System; Erythrocytes; Fungicides, Industrial; Glutathione Peroxidase; Hexachlorobenzene; Liver; Male; Oxidative Stress; Porphyrias; Rats; Rats, Wistar | 1997 |
Effect of estradiol on the induction of porphyria by hexachlorobenzene in the rat.
Topics: Animals; Castration; Estradiol; Female; Hexachlorobenzene; Inactivation, Metabolic; Male; Porphyrias; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sulfhydryl Compounds; Uroporphyrins | 1997 |
Liver cell cytoplasmic inclusions in experimental porphyrias: their demonstration with the ferric ferricyanide reduction reaction.
Topics: Animals; Benzamides; Disease Models, Animal; Female; Ferricyanides; Fungicides, Industrial; Herbicides; Hexachlorobenzene; Humans; Inclusion Bodies; Liver; Mice; Oxidation-Reduction; Polychlorinated Biphenyls; Porphyria Cutanea Tarda; Porphyrias; Rats; Rats, Wistar | 1997 |
Effect of alpha lipoic acid amide on hexachlorobenzene porphyria.
Topics: Animals; Female; Free Radical Scavengers; Hexachlorobenzene; Porphyrias; Rats; Rats, Wistar; Thioctic Acid; Time Factors | 1999 |
Porphyria-induced hepatic porphyrinogen carboxy-lyase inhibitor and its interaction with the active site(s) of the enzyme.
Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Enzyme Inhibitors; Female; Hexachlorobenzene; Humans; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Wistar; Uroporphyrinogens | 1999 |
Heme metabolism and lipid peroxidation in rat kidney hexachlorobenzene-induced porphyria: A compartmentalized study of biochemical pathogenic mechanisms.
Topics: Animals; Biomarkers; Enzyme Inhibitors; Female; Heme; Hexachlorobenzene; Kidney; Kidney Cortex; Lipid Peroxidation; Liver; Malondialdehyde; Porphyrias; Porphyrins; Rats; Rats, Wistar; Uroporphyrinogen Decarboxylase | 2000 |
Heme metabolism after discontinued hexachlorobenzene administration in rats: possible irreversible changes and biomarker for hexachlorobenzene persistence.
Topics: Adipose Tissue; Animals; Animals, Outbred Strains; Biomarkers; Drug Administration Schedule; Enzyme Inhibitors; Female; Fungicides, Industrial; Heme; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Wistar; Time Factors; Uroporphyrinogen Decarboxylase | 2000 |
Phospholipid alterations elicited by hexachlorobenzene in rat brain are strain-dependent and porphyria-independent.
Topics: Animals; Brain; Female; Hexachlorobenzene; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Porphyrias; Porphyrins; Rats; Rats, Wistar; Species Specificity; Sphingomyelins | 2001 |
Studies on the mechanism of the changes in serum and liver gamma-glutamyl transpeptidase activity. II. Experimental hexachlorobenzene porphyria in rabbits.
Topics: Acetylglucosaminidase; Animals; gamma-Glutamyltransferase; Hexachlorobenzene; Liver; Mannosidases; Porphyrias; Porphyrins; Rabbits | 1976 |
Macrocyclic intermediates in the biosynthesis of porphyrins.
Topics: Animals; Chickens; Coproporphyrinogens; Hexachlorobenzene; Humans; Porphyrias; Porphyrins; Protoporphyrins; Rats; Uroporphyrinogens | 1976 |
Letter: Gamma-benzene hexachloride toxicity.
Topics: Chemical and Drug Induced Liver Injury; Hexachlorobenzene; Hexachlorocyclohexane; Humans; Infant; Isomerism; Liver; Porphyrias; Scabies; Structure-Activity Relationship | 1975 |
Assessment of the contribution of chlorinated dibenzo-p-dioxins and dibenzofurans to hexachlorobenzene-induced toxicity, porphyria, changes in mixed function oxygenases, and histopathological changes.
Topics: Animals; Benzofurans; Body Weight; Chlorobenzenes; Dioxins; Drug Contamination; Female; Hexachlorobenzene; Liver; Lung; Mixed Function Oxygenases; Polychlorinated Biphenyls; Porphyrias; Rats | 1978 |
Cutaneous cytochrome P-450 activity during hexachlorobenzene-induced experimental porphyria in rats.
Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Microsomes; Microsomes, Liver; Porphyrias; Rats; Skin | 1979 |
A difference between two strains of rats in their liver non-haem iron content and in their response to the porphyrogenic effect of hexachlorobenzene.
Topics: 5-Aminolevulinate Synthetase; Animals; Dicarbethoxydihydrocollidine; Female; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1979 |
Chlorinated benzene induction of hepatic porphyria.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Organ Size; Porphyrias; Rats | 1977 |
Porphyrins and porphyrinogen carboxy-lase in hexachlorobenzene-induced porphyria.
Topics: Animals; Carboxy-Lyases; Chromatography, Gel; Female; Hexachlorobenzene; Porphyrias; Porphyrins; Rats; Tissue Distribution; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 1977 |
Hexachlorobenzene porphyria and hexachlorobenzene catabolism in rats.
Topics: Adipose Tissue; Animals; Chlorobenzenes; Feces; Female; Hexachlorobenzene; Kinetics; Liver; Male; Porphyrias; Rats | 1978 |
[Porphyria symptoms and microsomal enzyme activity in rat liver following administration of hexachlorobenzene].
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorobenzenes; Female; Hexachlorobenzene; Microsomes, Liver; Porphyrias; Rats | 1978 |
[Hexachlorbenzene (HCB) induced porphyria in rats. Influence of HCB-metabolites on the biosynthesis of heme (author's transl)].
Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Pentachlorophenol; Porphyrias; Rats | 1978 |
The use of the rat in the experimental investigation of the porphyrias.
Topics: Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Drug Evaluation, Preclinical; Female; Hexachlorobenzene; Liver; Male; Porphyrias; Rats; Uroporphyrins | 1978 |
Simplified method for the determination of porphyrins in body fluids.
Topics: Animals; Hexachlorobenzene; Humans; Lead Poisoning; Methods; Porphyrias; Porphyrins; Rabbits; Rats | 1977 |
Toxic effects of hexachlorobenzene after daily administration to beagle dogs for one year.
Topics: Adipose Tissue; Animals; Bile; Body Weight; Chlorobenzenes; Dogs; Female; Hexachlorobenzene; Leukocyte Count; Male; Neutrophils; Porphyrias; Porphyrins; Rats; Time Factors | 1977 |
Effects of hexachlorobenzene feeding and iron overload on enzymes of haem biosynthesis and cytochrome P 450 in rat liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Siderosis; Time Factors; Uroporphyrinogen Decarboxylase | 1977 |
Hepatic haem metabolism in porphyria cutanea tarda (PCT): enzymatic studies and their relation to liver ultrastructure.
Topics: Aminopyrine; Animals; Benzopyrenes; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Hexachlorobenzene; Humans; Hydroxylation; Iron; Liver; Microscopy, Electron; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats | 1976 |
Hexachlorobenzene porphyria in rats as a model for human chronic hepatic porphyrias.
Topics: Aminolevulinic Acid; Animals; Chlorobenzenes; Chronic Disease; Coproporphyrins; Disease Models, Animal; Female; Hexachlorobenzene; Kidney; Liver; Porphyrias; Porphyrins; Protoporphyrins; Rats; Spleen; Uroporphyrins | 1976 |
Hexachlorobenzene-induced porphyria in rats--relationship between prophyrin excretion and induction of drug metabolizing liver enzymes.
Topics: Aminolevulinic Acid; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Hexachlorobenzene; Liver; Male; Porphyrias; Porphyrins; Proteins; Rats; Time Factors; Triglycerides | 1975 |
Chemical (HCB) porphyria: effect of removal of sex organs in the rat.
Topics: Animals; Castration; Chlorobenzenes; Diet; Female; Hexachlorobenzene; Liver; Male; Ovary; Porphyrias; Porphyrins; Rats; Sex Factors; Testis; Time Factors | 1975 |
Skin porphyrin and photosensitivity in the porphyric rat.
Topics: Animals; Feces; Female; Hexachlorobenzene; Light; Male; Porphyrias; Porphyrins; Rats; Skin | 1975 |
Modulation of hexachlorobenzene-induced hepatic porphyria by methyl isobutyl ketone in the rat.
Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Female; Hexachlorobenzene; Liver Diseases; Methyl n-Butyl Ketone; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1992 |
Influence of hepatic tumors caused by diethylnitrosamine on hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Hexachlorobenzene; Liver; Liver Neoplasms; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1991 |
Sex comparison of heme pathway in rats bearing hepatic tumors.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hydroxymethylbilane Synthase; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Sex Characteristics | 1991 |
Development of an experimental model for the study of hexachlorobenzene-induced hepatic porphyria in the rat.
Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Hexachlorobenzene; Liver; Liver Diseases; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrins | 1991 |
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Mechanism of drug action.
Topics: Animals; Binding Sites; Chromatography, Gel; Copper; Copper Sulfate; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hot Temperature; Liver; Pentachlorophenol; Porphyrias; Porphyrins; Protein Conformation; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Spectrophotometry | 1991 |
Studies on the active centre of rat liver porphyrinogen carboxylase in vivo effect of hexachlorobenzene.
Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Diethyl Pyrocarbonate; Epoxy Compounds; Female; Hexachlorobenzene; Histidine; Hydroxylamine; Hydroxylamines; Liver; Methylene Blue; Photochemistry; Porphyrias; Rats; Rats, Inbred Strains; Spectrophotometry; Uroporphyrinogens | 1991 |
Effect of UVASUN on porphyrin metabolism and P-450 isoenzymes in hexachlorobenzene-induced porphyric rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Isoenzymes; Liver Diseases; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Nude; Skin; Skin Diseases; Ultraviolet Rays | 1991 |
Iron and uroporphyrin in hepatocytes of inbred mice in experimental porphyria: a biochemical and morphological study.
Topics: Animals; Drug Combinations; Hexachlorobenzene; Iron; Iron-Dextran Complex; Liver; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Porphyrias; Uroporphyrins | 1991 |
Bile and biliary lipid secretion in rats with hexachlorobenzene-induced porphyria. Effect of S-adenosyl-L-methionine administration.
Topics: Animals; Bile; Bile Ducts; Bilirubin; Cholesterol; Female; Hexachlorobenzene; Injections, Subcutaneous; Lipid Metabolism; Liver; Organ Size; Phospholipids; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1991 |
Decreased activity of liver coproporphyrinogen oxidase in hexachlorobenzene-induced porphyria.
Topics: Animals; Chromatography, High Pressure Liquid; Coproporphyrinogen Oxidase; Coproporphyrins; Hexachlorobenzene; Hydrogen-Ion Concentration; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Porphyrias; Time Factors | 1990 |
Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls.
Topics: Animals; Aroclors; Chemical and Drug Induced Liver Injury; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Immunohistochemistry; Liver Diseases; Male; Microsomes, Liver; Oxidation-Reduction; Polybrominated Biphenyls; Porphyrias; Rats; Rats, Inbred F344; Sex Factors; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1990 |
Synergistic effect of mammary tumors on hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Female; Hexachlorobenzene; Mammary Neoplasms, Experimental; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1990 |
Is hexachlorobenzene human overload related to porphyria cutanea tarda? A speculative hypothesis.
Topics: Body Burden; Environmental Exposure; Hexachlorobenzene; Humans; Porphyrias; Skin Diseases; Spain | 1990 |
Protective effect of S-adenosyl-L-methionine in hepatic uroporphyria. Evaluation in an experimental model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Hexachlorobenzene; Liver Diseases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Skin Diseases; Uroporphyrinogen Decarboxylase | 1990 |
Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Chlorobenzenes; Dose-Response Relationship, Drug; Female; Hexachlorobenzene; Iodine Radioisotopes; Liver; Organ Size; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroxine; Triiodothyronine | 1990 |
[Study of the origin of urinary porphyrins in experimental hexachlorobenzene-induced porphyria ].
Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Hexachlorobenzene; Kidney; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Rats; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1990 |
Dose-response relationships in hexachlorobenzene-induced porphyria.
Topics: Administration, Oral; Animals; Body Weight; Chlorobenzenes; Dose-Response Relationship, Drug; Female; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Hexachlorobenzene episode in Turkey.
Topics: Adolescent; Child; Child, Preschool; Chlorobenzenes; Disease Outbreaks; Feces; Female; Follow-Up Studies; Hexachlorobenzene; Humans; Infant; Male; Milk, Human; Porphyrias; Porphyrins; Skin Diseases; Turkey | 1989 |
Sexual dimorphism of cytochrome P-450 induction by hexachlorobenzene in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Liver; Liver Neoplasms, Experimental; Male; Porphyrias; Rats; Rats, Inbred F344; Sex Characteristics | 1989 |
Hepatic mitochondrial oxidative metabolism and lipid peroxidation in experimental hexachlorobenzene-induced porphyria with dietary carbonyl iron overload.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Diet; Female; Hexachlorobenzene; Iron; Iron Carbonyl Compounds; Lipid Peroxidation; Mitochondria, Liver; Organometallic Compounds; Oxidation-Reduction; Oxygen Consumption; Porphyrias; Rats; Rats, Inbred Strains | 1989 |
Modulation of hepatic heme-binding Z protein in mice by the porphyrogenic carcinogens griseofulvin and hexachlorobenzene.
Topics: Animals; Blotting, Western; Carcinogens; Carrier Proteins; Chlorobenzenes; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Griseofulvin; Heme; Heme-Binding Proteins; Hemeproteins; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Porphyrias | 1989 |
Hexachlorobenzene as a promoter of diethylnitrosamine-initiated hepatocarcinogenesis in rats and comparison with induction of porphyria.
Topics: Animals; Body Weight; Carcinogens; Chlorobenzenes; Diethylnitrosamine; Female; Hexachlorobenzene; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Porphyrias; Rats; Rats, Inbred F344; Reference Values; Sex Factors | 1989 |
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Studies on their properties.
Topics: Animals; Chlorobenzenes; Enzyme Stability; Ferrochelatase; Heme; Hexachlorobenzene; Hydrogen-Ion Concentration; Lyases; Mitochondria, Liver; Porphyrias; Rats | 1989 |
Influence of the strain of rats on the induction of hexachlorobenzene induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Liver; Liver Diseases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Species Specificity | 1989 |
Development of hexachlorobenzene porphyria in rats: time sequence and relationship with lipid peroxidation.
Topics: Animals; Chlorobenzenes; Fatty Acids; Female; Free Radicals; Hexachlorobenzene; Lipid Peroxidation; Liver; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors; Uroporphyrinogen Decarboxylase | 1989 |
The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme Inhibitors; Female; Hexachlorobenzene; Hydroquinones; In Vitro Techniques; Liver Diseases; Male; Microsomes, Liver; Oxidation-Reduction; Pentachlorophenol; Porphyrias; Rats; Rats, Inbred Strains; Troleandomycin | 1989 |
The role of the Ah locus in hexachlorobenzene-induced porphyria. Studies in congenic C57BL/6J mice.
Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Genes; Hexachlorobenzene; Isoenzymes; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Uroporphyrinogen Decarboxylase | 1988 |
Changes in some intestinal enzyme activities in experimental hexachlorobenzene-induced porphyria and modifying effects of diet.
Topics: Animals; beta-Glucosidase; Chlorobenzenes; Diet; Dietary Carbohydrates; Disaccharidases; gamma-Glutamyltransferase; Hexachlorobenzene; Intestines; Male; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Carcinogenicity of iron in conjunction with a chlorinated environmental chemical, hexachlorobenzene, in C57BL/10ScSn mice.
Topics: Animals; Chlorobenzenes; Drug Synergism; Hexachlorobenzene; Hypertrophy; Iron; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Porphyrias | 1989 |
Ability of several hexachlorobenzene metabolites to induce porphyrin accumulation in chick embryo liver "in ovo".
Topics: Animals; Chick Embryo; Chlorobenzenes; Hexachlorobenzene; Liver; Phenobarbital; Phenols; Porphyrias; Porphyrins; Sulfur | 1985 |
The role of iron in the hexachlorobenzene induced porphyria. I. Studies on different types of iron and its relation with porphyrinogen carboxy-lyase decrease.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Disease Models, Animal; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1985 |
The role of contaminants in hexachlorobenzene toxicity.
Topics: Animals; Chlorobenzenes; Cytochrome P-450 CYP1A1; Drug Contamination; Female; Hexachlorobenzene; Mice; Mice, Inbred Strains; Oxidoreductases; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1986 |
Neurotoxicity of hexachlorobenzene-induced porphyria turcica.
Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Myotonia; Nervous System Diseases; Peripheral Nervous System Diseases; Porphyrias; Porphyrins | 1986 |
Porphyria turcica: hexachlorobenzene-induced porphyria. Neurological manifestations and therapeutic trials of ethylenediaminetetracetic acid in the acute syndrome.
Topics: Acute Disease; Chlorobenzenes; Edetic Acid; Hexachlorobenzene; Humans; Myotonia; Nervous System Diseases; Porphyrias; Syndrome; Thyroid Diseases | 1986 |
Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Hexachlorobenzene; Levulinic Acids; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 1988 |
Investigations on the role of free radical processes in hexachlorobenzene-induced porphyria in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Free Radicals; Hexachlorobenzene; Iron; Lipid Peroxides; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Xanthine Oxidase | 1988 |
Distinction between octachlorostyrene and hexachlorobenzene in their potentials to induce ethoxyphenoxazone deethylase and cause porphyria in rats and mice.
Topics: Animals; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hexachlorobenzene; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Porphyrias; Rats; Rats, Inbred F344; Styrenes; Uroporphyrinogen Decarboxylase | 1986 |
[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene].
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Deferoxamine; Hexachlorobenzene; Liver; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Remission Induction; Skin Diseases | 1987 |
The effect of iron overload on the mitochondrial porphyrin level in the hexachlorobenzene induced experimental porphyria.
Topics: Animals; Cell Membrane Permeability; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Liver; Mitochondria, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Valinomycin | 1988 |
Alterations of uroporphyrinogen decarboxylase by chlorinated organics.
Topics: Animals; Bromobenzenes; Carboxy-Lyases; Chlorobenzenes; Dioxins; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Sulfhydryl Reagents; Uroporphyrinogen Decarboxylase | 1987 |
Turkish epidemic hexachlorobenzene porphyria. A 30-year study.
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorobenzenes; Disease Outbreaks; Female; Hexachlorobenzene; Humans; Male; Middle Aged; Porphyrias; Retrospective Studies | 1987 |
Diet and alcohol effects on the manifestation of hepatic porphyrias.
Topics: Alcohol Drinking; Bloodletting; Diabetes Mellitus; Diet; Hexachlorobenzene; Humans; Iron; Liver Diseases; Porphyrias; Porphyrins; Skin Diseases; Turkey | 1987 |
[Toxicologic profile of hexachlorobenzene].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Environmental Exposure; Hexachlorobenzene; Humans; Immunity; Lethal Dose 50; Porphyrias; Tissue Distribution | 1987 |
Liver porphyrinogen carboxylase in hexachlorobenzene porphyric rats. Studies with intermediate porphyrinogens of series III and with uroporphyrinogen I.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Porphyrias; Porphyrinogens; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 1987 |
Experimental hepatic porphyria caused by hexachlorobenzene: mechanism of the metabolic block.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Hexachlorobenzene; Humans; Liver; Porphyrias; Uroporphyrinogen Decarboxylase | 1986 |
Genetic, iron status and sex factors of porphyria induced by hexachlorobenzene.
Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Lipid Peroxides; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Polychlorinated Dibenzodioxins; Porphyrias; Rats; Sex Factors; Species Specificity; Uroporphyrinogen Decarboxylase | 1986 |
Immunochemical studies of the uroporphyrinogen decarboxylase defect caused by hexachlorobenzene.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Ethylmaleimide; Female; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1986 |
Porphyrinogenic effect of hexachlorobenzene and 2,3,7,8-tetrachlorodibenzo-para-dioxin: is an inhibitor involved in uroporphyrinogen decarboxylase inactivation?
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Dioxins; Hexachlorobenzene; Kinetics; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Porphyrias; Uroporphyrinogen Decarboxylase | 1986 |
Porphyrins and pentachlorophenol in rat-liver mitochondria in hexachlorobenzene-induced porphyria.
Topics: Animals; Chlorobenzenes; Chlorophenols; Female; Hexachlorobenzene; Mitochondria, Liver; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
Hexachlorobenzene alteration of benzo[a]pyrene metabolism in porphyric and non-porphyric rats.
Topics: Animals; Benzo(a)pyrene; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Drug-induced uroporphyria in chicken hepatocyte cultures.
Topics: Animals; Cells, Cultured; Chickens; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Uroporphyrins | 1986 |
Accumulation of uroporphyrin does not provoke further inhibition of liver uroporphyrinogen decarboxylase activity in hexachlorobenzene-induced porphyria.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred C57BL; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1986 |
Japanese quail as a model for the study of hexachlorobenzene-induced porphyria.
Topics: Animals; Chlorobenzenes; Coturnix; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hexachlorobenzene; Mice; Mice, Inbred C57BL; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Does feeding of hexachlorobenzene promote structural changes in rat-liver porphyrinogen carboxy-lyase?
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Female; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Rat-liver porphyrinogen carboxy-lyase inhibition as a function of the degree of hexachlorobenzene-induced porphyria.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Hexachlorobenzene; Liver; Porphyrias; Rats | 1986 |
Studies on the role of iron in the alterations observed in hexachlorobenzene-induced porphyria.
Topics: Animals; Carboxy-Lyases; Chelating Agents; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Effect of an iron chelator on the onset of hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Enzyme Induction; Female; Hexachlorobenzene; Iron Chelating Agents; Porphyrias; Rats | 1986 |
Effects of chloroquine and hydroxychloroquine on the hexachlorobenzene-induced porphyria in rats.
Topics: Animals; Chlorobenzenes; Chloroquine; Female; Hexachlorobenzene; Hydroxychloroquine; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
Induction of porphyria in cultured chick-embryo hepatocytes by halogenated aromatic compounds.
Topics: Animals; Cells, Cultured; Chick Embryo; Chlorobenzenes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hexachlorobenzene; Liver; Methylcholanthrene; Porphyrias; Uroporphyrins | 1986 |
Introduction to the porphyrias.
Topics: Chlorobenzenes; Hexachlorobenzene; Humans; Porphyrias | 1986 |
Porphyria turcica: hexachlorobenzene-induced porphyria.
Topics: Adult; Chlorobenzenes; Female; Hexachlorobenzene; Humans; Male; Middle Aged; Milk, Human; Porphyrias; Porphyrins | 1986 |
The delay in polyhalogenated aromatic hydrocarbon-induced porphyria: mechanistic reality or methodological artefact?
Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chromatography, High Pressure Liquid; Female; Hexachlorobenzene; Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Disease Models, Animal; Female; Hexachlorobenzene; Iron; Liver; Organ Size; Porphyrias; Porphyrins; Rats; Skin Diseases | 1986 |
Lysosomes, but not mitochondria, accumulate iron and porphyrins in porphyria induced by hexachlorobenzene.
Topics: Animals; Centrifugation; Chelating Agents; Female; Hexachlorobenzene; Iron; Liver; Lysosomes; Mitochondria, Liver; Phenanthrolines; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
The delay in polyhalogenated aromatic hydrocarbon-induced porphyria: the effect of diet preparation.
Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chromatography, High Pressure Liquid; Corn Oil; Female; Food; Hexachlorobenzene; Intestinal Absorption; Organ Size; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
Mechanistic studies of the inhibition of hepatic uroporphyrinogen decarboxylase in C57BL/10 mice by iron-hexachlorobenzene synergism.
Topics: Alanine Transaminase; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytosol; Drug Synergism; Hexachlorobenzene; Iron; Lipid Metabolism; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oxidoreductases; Porphyrias; Species Specificity; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1986 |
Influence of chloroquine on the porphyrin metabolism.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Chloroquine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Hexachlorobenzene; Microsomes, Liver; Oxygenases; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1985 |
Hexachlorobenzene-induced porphyria in Japanese quail: an in vitro study of changes in cytochrome P-450 and monooxygenases.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxygenases; Porphyrias; Proadifen | 1985 |
Influence of (+)-propoxyphene on the hexachlorobenzene-induced porphyria of rats.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Chlorobenzenes; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Female; Hexachlorobenzene; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Porphyrias; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria.
Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Enzyme Induction; Female; Hexachlorobenzene; Liver Diseases; Microsomes, Liver; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1986 |
The involvement of iron and lipid peroxidation in the pathogenesis of HCB induced porphyria.
Topics: Animals; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Lipid Peroxides; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1985 |
The effect of tetrachlorohydroquinone on hexachlorobenzene-induced porphyria in Japanese quail.
Topics: 5-Aminolevulinate Synthetase; Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Coturnix; Drug Interactions; Female; Hexachlorobenzene; Hydroquinones; Lactose; Liver; Liver Diseases; Organ Size; Porphyrias; Porphyrins | 1985 |
A comparison of the effects of hexachlorobenzene, beta-naphthoflavone, and phenobarbital on cytochrome P-450 and mixed-function oxidases in Japanese quail.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Coturnix; Electrophoresis, Polyacrylamide Gel; Female; Flavonoids; Hexachlorobenzene; Injections, Intraperitoneal; Liver Diseases; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxygenases; Phenobarbital; Porphyrias | 1985 |
Hepatocarcinogenicity of hexachlorobenzene in rats and the sex difference in hepatic iron status and development of porphyria.
Topics: Animals; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Kidney; Liver; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred F344; Sex Factors; Uroporphyrinogen Decarboxylase | 1985 |
The role of pentachlorophenol in causing mitochondrial derangement in hexachlorobenzene induced experimental porphyria.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Female; Hexachlorobenzene; Liver; Liver Diseases; Membrane Potentials; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pentachlorophenol; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Uncoupling Agents | 1985 |
Influence of N-acetylcysteine on the hexachlorobenzene induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Acetylcysteine; Animals; Chlorobenzenes; Female; Glutathione; Hexachlorobenzene; Liver; Mixed Function Oxygenases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Hexachlorobenzene-induced porphyria in Japanese quail: changes in microsomal enzymes.
Topics: Animals; Chlorobenzenes; Coturnix; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glutathione Transferase; Hexachlorobenzene; Microsomes, Liver; Porphyrias; Porphyrins; Proteins | 1985 |
Fate of hexachlorobenzene in C57BL/10 mice with iron overload.
Topics: Animals; Carbon Radioisotopes; Chlorobenzenes; Hexachlorobenzene; Iron; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Porphyrias; Species Specificity; Tissue Distribution | 1985 |