hetacillin and Streptococcal-Infections

hetacillin has been researched along with Streptococcal-Infections* in 1 studies

Other Studies

1 other study(ies) available for hetacillin and Streptococcal-Infections

Article	Year
Hetacillin (R)- and (S)-sulfoxides. Synthesis and structure-activity relationships. Journal of medicinal chemistry, 1978, Volume: 21, Issue:2 Hetacillin was oxidized with m-chloroperbenzoic acid to give the corresponding (R)- and (S)-sulfoxides. Ozonization of hetacillin not only oxidized the sulfide but caused unexpected oxidation of the imidazolidine ring to a 2H-imidazoline. The biological spectrum showed the (R)-sulfoxide to be appreciably more active than the (S)-sulfoxide. Topics: Animals; Mice; Microbial Sensitivity Tests; Penicillins; Stereoisomerism; Streptococcal Infections; Streptococcus pyogenes; Structure-Activity Relationship; Sulfoxides	1978

Article

Year

Hetacillin (R)- and (S)-sulfoxides. Synthesis and structure-activity relationships.

Journal of medicinal chemistry, 1978, Volume: 21, Issue:2

Hetacillin was oxidized with m-chloroperbenzoic acid to give the corresponding (R)- and (S)-sulfoxides. Ozonization of hetacillin not only oxidized the sulfide but caused unexpected oxidation of the imidazolidine ring to a 2H-imidazoline. The biological spectrum showed the (R)-sulfoxide to be appreciably more active than the (S)-sulfoxide.

Topics: Animals; Mice; Microbial Sensitivity Tests; Penicillins; Stereoisomerism; Streptococcal Infections; Streptococcus pyogenes; Structure-Activity Relationship; Sulfoxides

1978