Page last updated: 2024-08-21

hesperidin and Insulin Resistance

hesperidin has been researched along with Insulin Resistance in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (40.00)24.3611
2020's9 (60.00)2.80

Authors

AuthorsStudies
Rabbani, N; Thornalley, PJ1
Chen, J; Ge, A; Ge, J; Wang, S; Xu, H; Yang, K; Yuan, X; Zeng, L; Zhang, T1
Dayarathne, LA; Han, CH; Lee, YJ; Natraj, P; Rajan, P; Ranaweera, SS1
Mohammadi, M; Mohsenpour, M; Ramezani-Jolfaie, N; Salehi-Abargouei, A; Shams-Rad, S; Zarei, S1
Akash, MSH; Arafa, EA; Buabeid, MA; Chohan, TA; Jabeen, K; Munawar, SM; Rehman, K; Tariq, M1
Bunbupha, S; Maneesai, P; Meephat, S; Pakdeechote, P; Prachaney, P; Prasatthong, P; Rattanakanokchai, S1
Alavian, SM; Cheraghpour, M; Eini-Zinab, H; Hedayati, M; Hekmatdoost, A; Yari, Z1
Bai, YF; Fan, XY; Lou, LJ; Sheng, H; Wang, SW; Weng, YY; Zhang, F1
Rabbani, N; Thornalley, PJ; Weickert, MO; Xue, M1
Pu, P1
Adorno, MAT; Cecatti, C; Cesar, TB; Fidélix, MP; Lima, ACD; Sakamoto, IK; Sivieri, K1
Aofei, T; Jiao, G; Longyan, Z; Tao, L; Weijian, B; Xuguang, H1
Cesar, TB; Manthey, JA; Ramos, FM; Ribeiro, CB1
Chen, K; Chen, Y; Hu, Y; Jia, S; Li, X; Sun, C; Zhang, W; Zhao, X1
Kai, H; Kawai, K; Ogata, K; Shuto, T; Takamura, N; Tokunaga, J; Yoshida, H1

Reviews

3 review(s) available for hesperidin and Insulin Resistance

ArticleYear
Emerging Glycation-Based Therapeutics-Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors.
    International journal of molecular sciences, 2022, Feb-23, Volume: 23, Issue:5

    Topics: Animals; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Induction; Glutathione; Glycosylation; Hesperidin; Humans; Insulin Resistance; Lactoylglutathione Lyase; Mice; Molecular Structure; Neoplasms, Experimental; Obesity; Pyruvaldehyde; Resveratrol

2022
Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Alanine Transaminase; Anthocyanins; Aspartate Aminotransferases; Catechin; Cholesterol, HDL; Cholesterol, LDL; Curcumin; Dietary Supplements; Genistein; Hesperidin; Humans; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Plant Extracts; Polyphenols; Resveratrol; Silymarin; Triglycerides

2022
Hesperidin supplementation has no effect on blood glucose control: A systematic review and meta-analysis of randomized controlled clinical trials.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:1

    Topics: Adult; Blood Glucose; Dietary Supplements; Glycated Hemoglobin; Hesperidin; Humans; Insulin Resistance

2020

Trials

4 trial(s) available for hesperidin and Insulin Resistance

ArticleYear
The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial.
    European journal of clinical nutrition, 2021, Volume: 75, Issue:1

    Topics: Dietary Supplements; Flax; Hesperidin; Humans; Insulin Resistance; Liver; Non-alcoholic Fatty Liver Disease

2021
Reversal of Insulin Resistance in Overweight and Obese Subjects by
    Nutrients, 2021, Jul-11, Volume: 13, Issue:7

    Topics: Adult; Blood Pressure; Body Mass Index; Carrier Proteins; Correlation of Data; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Female; Glucose Metabolism Disorders; Glycosylation; Hesperidin; Humans; Inflammation; Inflammation Mediators; Insulin Resistance; Leukocytes, Mononuclear; Male; Obesity; Overweight; Pyruvaldehyde; Resveratrol; Tumor Necrosis Factor-alpha

2021
Effect of Daily Consumption of Orange Juice on the Levels of Blood Glucose, Lipids, and Gut Microbiota Metabolites: Controlled Clinical Trials.
    Journal of medicinal food, 2019, Volume: 22, Issue:2

    Topics: Adult; Bifidobacterium; Biomarkers; Blood Glucose; Cholesterol, LDL; Citrus sinensis; Diet; Feeding Behavior; Female; Flavanones; Fruit; Fruit and Vegetable Juices; Gastrointestinal Microbiome; Hesperidin; Humans; Insulin; Insulin Resistance; Intestines; Lactobacillus; Lipids; Polymerase Chain Reaction; Reference Values; Young Adult

2019
Effectiveness of Eriomin® in managing hyperglycemia and reversal of prediabetes condition: A double-blind, randomized, controlled study.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:7

    Topics: Adult; Blood Glucose; Citrus; Double-Blind Method; Female; Flavanones; Glycated Hemoglobin; Hesperidin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Prediabetic State; Treatment Outcome

2019

Other Studies

8 other study(ies) available for hesperidin and Insulin Resistance

ArticleYear
Anti-diabetic effect of hesperidin on palmitate (PA)-treated HepG2 cells and high fat diet-induced obese mice.
    Food research international (Ottawa, Ont.), 2022, Volume: 162, Issue:Pt B

    Topics: Animals; Blood Glucose; Diet, High-Fat; Hep G2 Cells; Hesperidin; Humans; Insulin; Insulin Resistance; Mice; Mice, Obese; Palmitates

2022
Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Diet, High-Fat; Disease Models, Animal; Drug Therapy, Combination; Hesperidin; Hyperlipidemias; Inflammation; Insulin Resistance; Leptin; Molecular Docking Simulation; Molecular Dynamics Simulation; Obesity; Orlistat; Rats, Wistar

2020
Hesperidin ameliorates signs of the metabolic syndrome and cardiac dysfunction via IRS/Akt/GLUT4 signaling pathway in a rat model of diet-induced metabolic syndrome.
    European journal of nutrition, 2021, Volume: 60, Issue:2

    Topics: Animals; Blood Glucose; Diet, High-Fat; Glucose Transporter Type 4; Heart Diseases; Hesperidin; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2021
Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice.
    Nutrition & diabetes, 2020, 08-05, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Diet, High-Fat; Fatty Liver; Hep G2 Cells; Hesperidin; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Obesity; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

2020
[Protection mechanisms of hesperidin on mouse with insulin resistance].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:17

    Topics: Animals; Blood Glucose; Diet, High-Fat; Hesperidin; Hyperglycemia; Hyperlipidemias; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Signal Transduction

2016
Hesperidin ameliorates insulin resistance by regulating the IRS1-GLUT2 pathway via TLR4 in HepG2 cells.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:6

    Topics: Animals; Glucose; Glucose Transporter Type 2; Hep G2 Cells; Hesperidin; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; NF-kappa B; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2019
Hypoglycemic and hypolipidemic effects of neohesperidin derived from Citrus aurantium L. in diabetic KK-A(y) mice.
    Food & function, 2015, Volume: 6, Issue:3

    Topics: Adipose Tissue, White; Adiposity; Animals; Blood Proteins; Citrus; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Supplements; Gene Expression Regulation, Enzymologic; Glycated Serum Proteins; Glycoproteins; Hesperidin; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Random Allocation; Specific Pathogen-Free Organisms

2015
The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-alpha in mouse adipocytes.
    Biochemical and biophysical research communications, 2010, Apr-09, Volume: 394, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Citrus; Fatty Acids, Nonesterified; Flavanones; Flavonoids; Hesperidin; Insulin Resistance; Lipolysis; Mice; Tumor Necrosis Factor-alpha

2010