heroin and Water-Electrolyte-Imbalance

A report is presented on two patients with massive rhabdomyolysis following heroin intoxication. Due to massive muscle edema of the lower legs, both patients needed early fasciotomy to prevent compression syndrome. The two cases followed a different course as regards complications and especially renal insufficiency and disorders of serum calcium and phosphorus regulation. Pathophysiology, prevention and therapy of complications are discussed. As a result of intensive physiotherapy, the long term functional outcome was satisfactory in both cases.

Topics: Acute Kidney Injury; Adolescent; Adult; Female; Heroin; Heroin Dependence; Humans; Leg; Male; Rhabdomyolysis; Tomography, X-Ray Computed; Water-Electrolyte Imbalance