heroin and Virus-Diseases

heroin has been researched along with Virus-Diseases* in 1 studies

Other Studies

1 other study(ies) available for heroin and Virus-Diseases

ArticleYear
Community-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Fourteen previously healthy young patients with unusual community-acquired opportunistic infections were seen over a period of three years. They differ from patients previously described in that 11 were heterosexual drug abusers (including two women) and only three were homosexual men. There were eight Puerto Ricans, five blacks, and one white. Infections included Pneumocystis carinii pneumonia (seven), disseminated Mycobacterium intracellulare infection, histoplasmosis, cryptococcosis, and cytomegalovirus infection (one each), oral thrush (13), and Candida esophagitis (two). All patients had impaired cellular immunity manifested by cutaneous anergy and lymphopenia, and all 11 tested had a markedly decreased ratio of T helper/inducer cells to T suppressor/cytotoxic cells. Twelve had evidence of associated viral infection (Epstein-Barr virus in nine, cytomegalovirus in five, Herpes simplex type 2 in two). Clinical presentation was with a severe opportunistic infection or with a prodrome consisting of oral thrush and nonspecific findings including malaise, fever, lymphadenopathy, or cough. The syndrome of immunodeficiency and opportunistic infection occurs in nonwhite heterosexual drug abusers, not exclusively in white homosexual men, and patients may present for medical care before the onset of a severe opportunistic infection.

    Topics: Acquired Immunodeficiency Syndrome; Adult; Black People; Candidiasis, Oral; Female; Heroin; Homosexuality; Humans; Immunity, Cellular; Infections; Male; New York City; Pneumonia, Pneumocystis; Puerto Rico; Substance-Related Disorders; T-Lymphocytes; T-Lymphocytes, Regulatory; Virus Diseases

1983