heroin and Skin-Diseases

Topics: Cocaine; Heroin; Humans; Hypnotics and Sedatives; Methamphetamine; Skin Diseases; Skin Diseases, Infectious; Soft Tissue Infections; Substance Abuse Detection; Substance-Related Disorders

Medical complications of heroin overdose and the diseases of addicts play an increasingly important role in the daily routine of hospital medical departments. The percentage of drug-related admissions to the Medical Clinic of the University Hospital, Zürich, increased from 0.18% to 4.45% between 1972 and 1983. During this 12-year period, 492 patients were admitted 569 times because of heroin overdose or intoxications combined with other drugs, and 191 drug addicts were hospitalized 226 times for a variety of medical problems. Certain complications, such as heroin pulmonary edema and talc granulomas of the lung, occur only in parenteral drug addiction. Other diseases such as right heart endocarditis, Candida-endophthalmitis, septic arthritis and osteomyelitis are almost exclusively observed in intravenous drug abusers. Sexually transmitted infections and hepatitis B are frequently diagnosed in addicts.

Topics: Adolescent; Adult; Age Factors; Arthritis, Infectious; Candidiasis; Cardiovascular Diseases; Endocarditis, Bacterial; Female; Hepatitis, Viral, Human; Heroin; Heroin Dependence; Humans; Length of Stay; Lung Diseases; Male; Nervous System Diseases; Osteomyelitis; Pulmonary Edema; Rhabdomyolysis; Sex Factors; Sexually Transmitted Diseases; Skin Diseases; Switzerland

Topics: Acne Vulgaris; Adult; Aged; Anti-Bacterial Agents; Drug Eruptions; Eczema; Exostoses; Female; Heroin; Humans; Hypersensitivity; Lentigo; Lupus Erythematosus, Discoid; Male; Middle Aged; Porphyrias; Psoriasis; Scabies; Skin Diseases; Skin Neoplasms; Skin Ulcer; Tinea Versicolor; United States

Topics: Adult; Aged; Blood Pressure; Body Temperature; Body Weight; Cardiovascular Diseases; Female; Gastrointestinal Diseases; Heroin; Humans; Liver Diseases; Lung Diseases; Lymphatic Diseases; Male; Middle Aged; Morphine Dependence; Pulse; Skin Diseases; Splenic Diseases; Substance-Related Disorders; Urologic Diseases

In the 1994-1996 trial of medically controlled prescription of narcotics to dependent users, 800 places were ascribed to heroin substitutes and another 200 for methadone and morphine substitutes. The trial was evaluated with the aid of an accompanying research. Among the results demonstrated in the evaluation was an improvement of the health of the participants. The economic assessment was drawn from observations of health effects within a sub-sample of 142 participants from four centers. In a retrospective statistical survey, for each acute illness which could be influenced through the trial, the number of diagnoses was recorded in the first and thirteenth month after study entry. Also, based on a number of representative cases for each of these acute illnesses, the resource use, i.e. the types and numbers of medical products and services rendered to the patients, was recorded. The results showed a clear decline in depressive episodes, skin diseases, digestive system disorders as well as epileptic attacks and intoxication. Treatment costs could be reduced from a total of CHF 94875.--to CHF 21,998.--/month or from CHF 22.27 to CHF 5.15/patient per day. The improvement of somatic and psychic health due to the medically controlled prescription of narcotics resulted in a benefit of CHF 17.11/person per day.

Topics: Depression; Digestive System Diseases; Drug Prescriptions; Epilepsy; Health Care Costs; Heroin; Humans; Methadone; Morphine Derivatives; Narcotics; Opioid-Related Disorders; Retrospective Studies; Skin Diseases

Wound botulism in 7 heroin 'skin poppers' produced ophthalmoplegia and descending paralysis. Rapid recovery occurred in 2 who received the antitoxin within the fourth day of symptom onset. A poor outcome was seen in 4 who received the antitoxin after the eighth day of symptoms and 1 who did not receive the antitoxin. Early antitoxin administration is important in achieving a favorable outcome.

Topics: Abscess; Adult; Botulinum Antitoxin; Botulism; Female; Heroin; Humans; Injections, Subcutaneous; Male; Middle Aged; Skin Diseases; Treatment Outcome

Topics: Acute Kidney Injury; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Electrocardiography; Female; Fetal Diseases; Fetus; Heart Diseases; Hepatitis A; Heroin; Heroin Dependence; Humans; Hypertension, Pulmonary; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Lung Diseases; Male; Maternal-Fetal Exchange; Methods; Neurologic Manifestations; Pneumonia, Aspiration; Pregnancy; Pulmonary Edema; Pulmonary Embolism; Respiratory Insufficiency; Skin Diseases

Topics: Acanthosis Nigricans; Acne Vulgaris; Dental Caries; Dermatitis, Contact; Drug Eruptions; Edema; Gangrene; Hepatitis A; Heroin; Humans; Impetigo; Life Style; Pigmentation Disorders; Pruritus; Psychophysiologic Disorders; Purpura; Skin Diseases; Skin Manifestations; Substance-Related Disorders; Thrombophlebitis; Urticaria

Topics: Acute Kidney Injury; Adult; Coma; Contracture; Female; Heroin; Humans; Ischemia; Male; Muscles; Muscular Diseases; Pressure; Pressure Ulcer; Secobarbital; Skin Diseases; Substance-Related Disorders

Topics: Abscess; Chronic Disease; Criminal Psychology; Drug and Narcotic Control; Drug Contamination; Ethics, Medical; Heroin; Heroin Dependence; Humans; Methadone; Quinine; Skin Diseases; Terminology as Topic; United States

Topics: Adult; Animals; Drug Contamination; Heroin; Humans; Injections, Intradermal; Male; Mice; Quinine; Skin Diseases; Skin Tests; Substance-Related Disorders; Time Factors

Topics: Adolescent; Adult; Female; Heroin; Humans; Male; Morphine Dependence; New York; Pigmentation Disorders; Quinine; Skin Diseases; Substance-Related Disorders

Topics: Adult; Amobarbital; Barbiturates; Biopsy; Blister; Coma; Erythema; Heroin; Humans; Male; Nalorphine; Necrosis; Prednisone; Secobarbital; Skin; Skin Diseases; Sweat Glands