heroin and Hepatitis

A review of the clinical characteristics of heroin addiction and parameters surrounding outpatient and inpatient care of patients afflicted with heroin dependency is presented. A case report demonstrating the difficulties encountered when one elects to treat the heroin addict is included.

Topics: Adult; Dental Care for Disabled; Hepatitis; Heroin; HIV Seropositivity; Humans; Injections, Intravenous; Male; Mouth; Sepsis; Substance-Related Disorders

Topics: Adolescent; Adult; Endocarditis; Female; Hepatitis; Heroin; Humans; Lung Diseases; Male; Middle Aged; Substance-Related Disorders; Tetanus

Topics: Analgesics, Opioid; Communicable Diseases; Drug Users; Fentanyl; Hepatitis; Heroin; HIV Infections; Humans; Opioid-Related Disorders; Staphylococcal Infections; Staphylococcus aureus; United States

Topics: Candidiasis; Hepatitis; Heroin; Humans; Substance-Related Disorders

Topics: Adult; Autoantibodies; Bacterial Infections; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Diagnosis, Differential; Female; Halothane; Hepatitis; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis, Viral, Human; Heroin; Heroin Dependence; Humans; Hypergammaglobulinemia; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged

Topics: Apgar Score; Birth Weight; Breech Presentation; Chlorpromazine; Delivery, Obstetric; Female; Fetal Death; Hepatitis; Hernia, Inguinal; Heroin; Heroin Dependence; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Jaundice, Neonatal; Menstruation Disturbances; Pregnancy; Pregnancy Complications; Prenatal Care; Substance Withdrawal Syndrome; United States

Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Amphetamine; Barbiturates; Black or African American; Cannabis; Cocaine; Crime; Family Characteristics; Female; Florida; Health Surveys; Hepatitis; Heroin; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Prisons; Sex Factors; Sexually Transmitted Diseases; Socioeconomic Factors; Substance-Related Disorders

Topics: Adult; Alcoholic Beverages; Alcoholism; Antibodies, Viral; Antigens, Viral; Blood Proteins; Ethanol; Hemagglutination Inhibition Tests; Hepatitis; Heroin; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulins; Liver; Liver Function Tests; Long-Term Care; Methadone; Prospective Studies; Radioimmunoassay; Substance-Related Disorders; Time Factors

Topics: Adult; Age Factors; Amenorrhea; Endocarditis; Female; France; Gangrene; Hepatitis; Heroin; Humans; Injections; Male; Middle Aged; Morphinans; Pharmaceutic Aids; Sepsis; Sexually Transmitted Diseases; Skin Manifestations; Social Behavior Disorders; Social Conditions; Substance-Related Disorders

Topics: Adolescent; Adult; Cellulitis; Death Certificates; Ethnicity; Female; Hepatitis; Heroin; Hospitalization; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Narcotics; New York City; Pulmonary Edema; Seasons; Substance-Related Disorders

The rate of removal of a standard dose of 25 mg indocyanine green was studied in 67 patients at the bedside using dichromatic ear densitometry. The determination of the percentage disappearance rate per minute and the half life of the dye permitted separation of patients into three groups: those with normal liver function, those with liver damage, and a group taking opiates (9), anticonvulsants (8), phenylbutazone (2), haloperidol (1), and nitrofurantoin (1). The last group showed enhanced clearance of indocyanine green from the circulation.

Topics: Adult; Aged; Anticonvulsants; Densitometry; Drug Therapy; Ear, External; Female; Half-Life; Haloperidol; Hepatitis; Heroin; Humans; Indocyanine Green; Liver; Liver Cirrhosis; Male; Meperidine; Middle Aged; Morphine; Nitrofurantoin; Phenylbutazone; Stimulation, Chemical; Substance-Related Disorders

Topics: Adolescent; Adult; Arthritis, Infectious; Candidiasis; Chronic Disease; Female; Hepatitis; Heroin; Humans; Male; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Spondylitis; Staphylococcal Infections; Substance-Related Disorders

Thirty-three of 72 heroin addicts attending a recognized clinic for drug addition had a history of jaundice, but in only five was the serum positive for hepatitis-associated antigen (HAA) when examined by immunodiffusion, immunoelectro-osmophoresis and complement fixation. Two of these were repeatedly positive over an 8-12 month follow-up period and liver biopsy showed chronic persistent hepatitis. A third later developed acute hepatitis. A study of the injection habits suggested that the present low incidence of HAA and the decrease in number of cases with jaundice was probably related to the provision of free disposable syringes by the clinic since it was opened in 1968.

Topics: Biopsy; Complement Fixation Tests; Female; Hepatitis; Hepatitis B Antigens; Hepatitis B virus; Heroin; Humans; Immunodiffusion; Immunoelectrophoresis; Jaundice; Liver; Male; Substance-Related Disorders

Topics: Adolescent; Biliary Tract Diseases; Brain Diseases; Chemical and Drug Induced Liver Injury; Child; Chronic Disease; Electroencephalography; Exchange Transfusion, Whole Blood; Female; Hepatic Encephalopathy; Hepatitis; Heroin; Humans; Male; Methods; Neurologic Manifestations; Plasma Substitutes; Plasmapheresis

Topics: Adolescent; Adult; Amphetamine; Barbiturates; England; Female; Hepatitis; Heroin; Humans; Male; Substance-Related Disorders

Topics: Adult; Gynecomastia; Hepatitis; Heroin; Humans; Male; Substance-Related Disorders

Topics: Abscess; Arthritis; Arthritis, Infectious; Bacteroides; Benzoates; Brain Abscess; Camphor; Cellulitis; Endocarditis; Endocarditis, Bacterial; Endocarditis, Subacute Bacterial; Hepatitis; Hepatitis B virus; Heroin; Humans; Infections; Meningitis; Methicillin; Opium; Penicillin G; Pneumothorax; Sepsis; Staphylococcal Infections; Substance-Related Disorders; Toxicology

Topics: Hepatitis; Hepatitis A; Hepatitis, Viral, Human; Heroin; Humans