heroin and Failure-to-Thrive

Exposure to cocaine in utero results in behavioral and neurodevelopmental abnormalities that persist into adulthood. Conventional MR imaging has generally failed to reveal the expected structural lesions to explain these clinical findings. We report a case of focal MR imaging signal-intensity changes in the substantia nigra, locus ceruleus, and other selected nerve tracts and nuclei in a child exposed prenatally to cocaine and other drugs. The patient also had dilated cardiomyopathy.

Topics: Cardiomyopathy, Dilated; Child Development; Cocaine; Failure to Thrive; Female; Heroin; Humans; Infant; Magnetic Resonance Imaging; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Substance-Related Disorders; Substantia Nigra