heroin and Candidiasis

heroin has been researched along with Candidiasis* in 26 studies

Reviews

1 review(s) available for heroin and Candidiasis

ArticleYear
[Somatic symptoms in opiate abuse].
    Schweizerische medizinische Wochenschrift, 1985, Feb-16, Volume: 115, Issue:7

    Medical complications of heroin overdose and the diseases of addicts play an increasingly important role in the daily routine of hospital medical departments. The percentage of drug-related admissions to the Medical Clinic of the University Hospital, Zürich, increased from 0.18% to 4.45% between 1972 and 1983. During this 12-year period, 492 patients were admitted 569 times because of heroin overdose or intoxications combined with other drugs, and 191 drug addicts were hospitalized 226 times for a variety of medical problems. Certain complications, such as heroin pulmonary edema and talc granulomas of the lung, occur only in parenteral drug addiction. Other diseases such as right heart endocarditis, Candida-endophthalmitis, septic arthritis and osteomyelitis are almost exclusively observed in intravenous drug abusers. Sexually transmitted infections and hepatitis B are frequently diagnosed in addicts.

    Topics: Adolescent; Adult; Age Factors; Arthritis, Infectious; Candidiasis; Cardiovascular Diseases; Endocarditis, Bacterial; Female; Hepatitis, Viral, Human; Heroin; Heroin Dependence; Humans; Length of Stay; Lung Diseases; Male; Nervous System Diseases; Osteomyelitis; Pulmonary Edema; Rhabdomyolysis; Sex Factors; Sexually Transmitted Diseases; Skin Diseases; Switzerland

1985

Other Studies

25 other study(ies) available for heroin and Candidiasis

ArticleYear
Candida albicans lumbar spondylodiscitis in an intravenous drug user: a case report.
    BMC research notes, 2013, Dec-11, Volume: 6

    Spondylodiscitis leads to debility, and few data exist on Candida spondylodiscitis in patients with intravenous drug use.. We present a case of Candida albicans lumbar spondylodiscitis in a patient with intravenous drug use. This patient was treated with surgical debridement and 9 months of fluconazole therapy, and the neurological deficits resolved completely. The infection did not recur clinically or radiologically during 9 months of follow-up.. Although Candida albicans lumbar spondylodiscitis is rare, Candida should be suspected as a causative pathogen in patients with intravenous drug use except for Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis. As soon as Candida albicans lumbar spondylodiscitis is suspected, magnetic resonance imaging and percutaneous biopsy should be performed. Surgical intervention combined with treatment with antifungal medications can successfully eradicate the infection and resolve the neurological deficits.

    Topics: Adult; Candida albicans; Candidiasis; Discitis; Heroin; Humans; Injections, Intravenous; Lumbosacral Region; Male; Substance-Related Disorders

2013
Candida lusitaniae arthritis in an intravenous drug user.
    Mycoses, 2007, Volume: 50, Issue:5

    A case of arthritis of the right knee caused by Candida lusitaniae in a 29-year-old intravenous drug abuser is described. The diagnosis was based on the isolation of C. lusitaniae from synovial fluid and was supported by the presence of C. lusitaniae-specific DNA and high levels of (1-3)-beta-d-glucan (122 pg ml-1) in the same specimen. While the isolate was susceptible to amphotericin B and fluconazole in vitro, treatment with amphotericin B was not very effective. The patient achieved complete cure with fluconazole therapy only after undergoing synovectomy. To the best of our knowledge, this is the first report of arthritis caused by C. lusitaniae in an intravenous drug user.

    Topics: Adult; Amphotericin B; Arthritis, Infectious; Blood Sedimentation; Candida; Candidiasis; Fluconazole; Heroin; Humans; Injections, Intra-Articular; Knee Joint; Male; Protein C; Substance Abuse, Intravenous; Synovial Fluid; Treatment Outcome

2007
Candida albicans spondylodiscitis and vertebral osteomyelitis in patients with intravenous heroin drug addiction. Report of 3 new cases.
    The Journal of rheumatology, 1994, Volume: 21, Issue:5

    We describe 3 patients with a history of intravenous (iv) heroin addiction presenting with indolent, persisting lumbar pain. Clinical findings and initial investigations were unremarkable. Gallium scintigraphy revealed septic spondylodiscitis, and cultures of material obtained by biopsy were positive for Candida albicans in all 3 cases. Two patients were treated with iv amphotericin B and the other with fluconazole with excellent results. Surgical treatment was needed only in one patient because of neurological involvement.

    Topics: Adult; Candidiasis; Discitis; Female; Heroin; Humans; Lumbar Vertebrae; Male; Middle Aged; Osteomyelitis; Radiography; Substance Abuse, Intravenous; Thoracic Vertebrae

1994
Candida spondylodiscitis. Chronic illness due to heroin analgesia in an HIV positive person.
    The Journal of rheumatology, 1990, Volume: 17, Issue:4

    Topics: Adult; Analgesia; Candidiasis; Discitis; Heroin; HIV Seropositivity; Humans; Injections, Spinal; Male; Substance-Related Disorders

1990
Costochondral involvement in systemic candidiasis in heroin addicts: clinical, scintigraphic, and histologic features in 26 patients.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:6

    We studied the clinical, scintigraphic, and histopathologic characteristics of 26 intravenous drug abusers with costochondral involvement secondary to systemic infection with Candida albicans. The clinical findings were of a mass appearing in the anterior region of the thorax. In general, signs of inflammation were absent. Histopathologic study of this costochondral mass in 12 patients showed perichondritis in 100% and myositis in 87%, with secondary involvement of cartilage in 43% and of bone in 75%. Results of bone scintigrams using 99mTc-methylene diphosphonate were positive in only 7 of 15 patients (47%), with a correlation between positive uptake and osteitis. Gallium scintigraphy findings were positive in 9 of 10 patients (90%). The greater sensitivity of 67Ga was probably because the invariably present pericartilaginous inflammatory mass was not always accompanied by secondary cartilage and bone involvement.

    Topics: Adolescent; Adult; Candida albicans; Candidiasis; Cartilage; Female; Heroin; Humans; Male; Ribs; Substance-Related Disorders; Syndrome; Tomography, Emission-Computed

1988
Intervertebral infection due to Candida albicans in an intravenous heroin abuser.
    Annals of the rheumatic diseases, 1988, Volume: 47, Issue:6

    A 25 year old woman who had received intravenous heroin over one year previously developed an intervertebral abscess due to infection with Candida albicans. Immunological investigation of this patient showed no evidence of a specific defect in the host response to candida.

    Topics: Abscess; Adult; Candidiasis; Female; Heroin; Humans; Spinal Diseases; Substance-Related Disorders

1988
Systemic candidiasis in Spanish heroin addicts: a possible source of infection.
    The Journal of infectious diseases, 1987, Volume: 156, Issue:5

    Topics: Candida albicans; Candidiasis; Citrus; Heroin; Heroin Dependence; Humans; Spain

1987
[A red eye in intravenous drug use].
    Nederlands tijdschrift voor geneeskunde, 1987, Jul-25, Volume: 131, Issue:30

    Topics: Abscess; Adult; Candidiasis; Combined Modality Therapy; Endophthalmitis; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Streptococcal Infections

1987
Cutaneous, ocular, and osteoarticular candidiasis in patients who are not heroin addicts.
    The Journal of infectious diseases, 1987, Volume: 155, Issue:5

    Topics: Adult; Aged; Arthritis, Infectious; Candidiasis; Candidiasis, Cutaneous; Chorioretinitis; Heroin; Humans; Male; Osteoarthritis; Substance-Related Disorders

1987
Systemic candidiasis in heroin abusers. Cutaneous findings.
    International journal of dermatology, 1987, Volume: 26, Issue:5

    Systemic candidiasis in intravenous drug abusers (IVDA) is a new syndrome caused by Candida albicans and characterized by the sequential development of skin, eye, and osteoarticular lesions, which together form a typical clinical picture. We studied 30 patients with suggestive skin lesions: papules, nodules, and pustules in hair-bearing areas, particularly the scalp and beard area, associated with hair invasion by candidal hyphae. Ocular and osteoarticular involvement and presence of candidemia in some of the patients suggested blood-borne colonization of C. albicans. The infection has been related to "brown" heroin. The origin of C. albicans and the reasons for its exclusive localization in the skin and these organs are discussed. The characteristic clinical picture is widely different from that of classic disseminated candidiasis in immunodeficient patients. Therapy is also discussed.

    Topics: Adult; Candidiasis; Candidiasis, Cutaneous; Female; Heroin; Humans; Male; Substance-Related Disorders

1987
Candidiasis in heroin abusers.
    The Journal of infectious diseases, 1987, Volume: 155, Issue:3

    Topics: Candidiasis; Hepatitis; Heroin; Humans; Substance-Related Disorders

1987
Contaminated lemons as possible source of infection in heroin abusers with disseminated candidiasis.
    European journal of clinical microbiology, 1986, Volume: 5, Issue:4

    Topics: Candida albicans; Candidiasis; Citrus; Food Microbiology; Heroin; Humans; Substance-Related Disorders

1986
Systemic candidiasis in heroin abusers.
    The Journal of infectious diseases, 1986, Volume: 153, Issue:6

    Topics: Candidiasis; Citrus; Heroin; Humans; Substance-Related Disorders

1986
Fungal endophthalmitis in narcotic abusers. Medical and surgical therapy in 10 patients.
    The Medical journal of Australia, 1985, Apr-01, Volume: 142, Issue:7

    The presentation and management of 10 cases of proven or presumptive fungal endophthalmitis in narcotic-drug abusers is described. Miconazole was found to be an effective agent in some patients when administered in a dosage of 2400 mg/day. Eight patients received treatment with a combination of miconazole and flucytosine (5-fluorocytosine). Regression of the infection with preservation of the eye was observed in each case. However, visual acuity in the affected eye improved only in four of the eight patients; it was unchanged in two and had deteriorated in the other two. In two patients, who received amphotericin B and flucytosine as initial treatment, control of the infection was achieved, but vision remained unchanged. Vitrectomy was performed in three patients to remove residual sites of infection. However, vision remained unchanged in two of these patients and worsened in the third. The selection of individual modalities of therapy and responses to treatment are discussed.

    Topics: Adult; Amphotericin B; Candidiasis; Drug Therapy, Combination; Endophthalmitis; Female; Flucytosine; Heroin; Humans; Male; Miconazole; Mycoses; Substance-Related Disorders; Visual Acuity; Vitrectomy

1985
Disseminated candidiasis with extensive folliculitis in abusers of brown Iranian heroin.
    European journal of clinical microbiology, 1985, Volume: 4, Issue:3

    Two cases of heroin abusers who developed disseminated candidiasis are reported. Cultures of skin lesions revealed Candida albicans, which on histology were shown to be located in and around hair shafts. Both patients recovered after treatment with amphotericin B combined with 5-fluorocytosine and either ketoconazole or dexamethasone. This unusual cutaneous syndrome of candidal infection associated with extensive folliculitis seems to be related to the use of a particular type of heroin, the so-called brown Iranian heroin.

    Topics: Adult; Amphotericin B; Candidiasis; Conjunctivitis; Female; Flucytosine; Folliculitis; Heroin; Humans; Iran; Ketoconazole; Male; Substance-Related Disorders

1985
Exogenous ocular candidiasis associated with intravenous heroin abuse.
    The British journal of ophthalmology, 1984, Volume: 68, Issue:11

    Seven young men developed disseminated candidiasis within 10 days of a single episode of intravenous heroin abuse. Sequential development of eye and skin lesions was noted in all cases. The bone or costal cartilage was involved in five. Ocular manifestations of candidiasis included episcleritis, chorioretinitis, and endophthalmitis. A presumptive diagnosis of candida chorioretinitis was established rapidly by culture of Candida albicans from involved skin and costal cartilage. Systemic therapy with amphotericin B plus 5-fluorocytosine resulted in cure of the episcleritis, chorioretinitis, osteomyelitis, costochondritis, and skin infection. Pars plana vitrectomy with local instillation of amphotericin B was required to cure chorioretinitis associated with vitreal extension of infection.

    Topics: Adult; Amphotericin B; Candidiasis; Eye Diseases; Flucytosine; Heroin; Humans; Male; Substance-Related Disorders

1984
Disseminated candidiasis: evidence of a distinctive syndrome in heroin abusers.
    British medical journal (Clinical research ed.), 1983, Sep-24, Volume: 287, Issue:6396

    Seven young men developed similar manifestations of disseminated candidiasis after a single episode of intravenous heroin abuse. Sequential development of lesions of the eye, skin, and bone or costal cartilage was noted within 10 days after injection. Skin lesions were confined to the scalp and other hair bearing areas. Candida albicans was cultured readily from affected skin and costal cartilage. Histological examination of scalp biopsy specimens showed infiltration of hair follicles with chronic inflammatory cells and C albicans. Pseudohyphas of C albicans were also identified in and around hair shafts. The skin, skeletal, and small eye lesions resolved on systemic treatment with 1 g amphotericin B plus flucytosine. Pars plana vitrectomy plus local instillation of amphotericin B cured progressive chorioretinitis. These features may represent a distinctive syndrome of disseminated candidiasis in heroin abusers. Systemic antifungal treatment is curative in most cases.

    Topics: Candidiasis; Candidiasis, Cutaneous; Eye Diseases; Heroin; Humans; Male; Osteochondritis; Osteomyelitis; Ribs; Substance-Related Disorders; Syndrome

1983
[Candida albicans endophthalmitis caused by intravenous heroin abuse].
    Nederlands tijdschrift voor geneeskunde, 1983, Feb-05, Volume: 127, Issue:6

    Topics: Adult; Amphotericin B; Candidiasis; Diagnosis, Differential; Endophthalmitis; Female; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Toxoplasmosis, Ocular

1983
[Candida endophthalmitis secondary to the use of intravenous heroin].
    Medicina clinica, 1983, Nov-12, Volume: 81, Issue:15

    Topics: Adult; Candidiasis; Endophthalmitis; Heroin; Humans; Injections, Intravenous; Male

1983
Candida endophthalmitis and drug abuse.
    Australian journal of ophthalmology, 1980, Volume: 8, Issue:4

    Candida endophthalmitis after intravenous heroin is described. Our patient had an initial rapid deterioration on systemic corticosteroids. Systemic amphotericin B, 5 flucytosine, vitrectomy and retinal surgery were required to achieve a final visual acuity of 6/24. The difficulty of an early diagnosis and the deleterious effect of corticosteroid use are emphasized.

    Topics: Adult; Candidiasis; Eye Diseases; Heroin; Humans; Inflammation; Injections, Intravenous; Male; Substance-Related Disorders

1980
Heroin-associated infective endocarditis. A report of 28 cases.
    Annals of internal medicine, 1973, Volume: 78, Issue:5

    Topics: Adult; Candida; Candidiasis; Endocarditis, Bacterial; Female; Haemophilus Infections; Haemophilus influenzae; Heart Failure; Heroin; Heroin Dependence; Humans; Male; Neurologic Manifestations; Panophthalmitis; Skin Manifestations; Splenomegaly; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Substance-Related Disorders

1973
Vascular complications of drug abuse.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:6

    Topics: Adult; Amphetamine; Amputation, Surgical; Aneurysm; Angiography; Arm; Arteries; Barbiturates; Blood Vessels; Candidiasis; Codeine; Endocarditis, Bacterial; Female; Heparin; Heroin; Humans; Injections, Intra-Arterial; Ischemia; Leg; Male; Methylphenidate; Substance-Related Disorders; Vascular Diseases; Vasodilator Agents; Veins

1972
Fungal endocarditis secondary to drug addiction. Recent concepts in diagnosis and therapy.
    The Journal of thoracic and cardiovascular surgery, 1972, Volume: 63, Issue:6

    Topics: Adult; Amphotericin B; Aortic Valve Insufficiency; Benzene Derivatives; Candidiasis; Endocarditis; Female; Flucytosine; Follow-Up Studies; Heart Septal Defects, Ventricular; Heart Valve Prosthesis; Heroin; Humans; Imidazoles; Male; Mitral Valve Insufficiency; Oxacillin; Pacemaker, Artificial; Radiography, Thoracic; Substance-Related Disorders; Tricuspid Valve Insufficiency

1972
Osteomyelitis in heroin addicts.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Adolescent; Adult; Arthritis, Infectious; Candidiasis; Chronic Disease; Female; Hepatitis; Heroin; Humans; Male; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Spondylitis; Staphylococcal Infections; Substance-Related Disorders

1971
Endocarditis in heroin addicts.
    British heart journal, 1969, Volume: 31, Issue:5

    Topics: Adult; Candidiasis; Endocarditis; Heroin; Humans; Injections, Intravenous; Male; Morphine Dependence; Pseudomonas Infections; Pulmonary Embolism; Staphylococcal Infections; Sterilization; Tricuspid Valve

1969