herbacetin has been researched along with Obesity* in 1 studies
1 other study(ies) available for herbacetin and Obesity
| Article | Year |
|---|---|
Herbacetin, a flaxseed flavonoid, ameliorates high percent dietary fat induced insulin resistance and lipid accumulation through the regulation of hepatic lipid metabolizing and lipid-regulating enzymes.
Healthy plants and their constituents have been considered as a safe remedy for the treatment of obesity and obesity associated diseases. Herbacetin is a dietary flavonoid that has been explored for many pharmacological activities; but, the anti-hyperglycaemic and anti-hyperlipidemic properties of herbacetin have not yet been explored. The present study was performed to evaluate the ameliorative effect of herbacetin on high-fat diet-induced hyperglycaemia and hyperlipidemia in 57BL/6 J mice. Obesity associated insulin resistance was induced by continuously feeding the mice with high-fat diet for 10 weeks. Afterwards, mice were subjected to intragastric administration of herbacetin (different doses) daily along with high-fat diet for the next 5 weeks. At the end of 106 Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Diet, High-Fat; Fatty Acid Synthases; Flavonoids; Flax; Glucosephosphate Dehydrogenase; Hyperglycemia; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Sterol Regulatory Element Binding Protein 2; Triglycerides | 2018 |