heptachlor has been researched along with Pregnancy in 29 studies
Heptachlor: A man-made compound previously used to control termites and other insects. Even though production of heptachlor was phased out of use in the United States during the late 1980's it remains in soil and hazardous waste sites. It is clearly toxic to animals and humans but, the International Agency for Research on Cancer (IARC) has determined that heptachlor is not classifiable as to its carcinogenicity to humans. (From ATSDR Public Heath Statement, April 1989)
heptachlor : A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult female Sprague-Dawley rats were injected with 5 or 20 mg/kg body weight heptachlor solution every other day for up to 18 days." | 7.69 | Effects of graded doses of the pesticide heptachlor on body weight, mating success, oestrous cycle, gestation length and litter size in laboratory rats. ( Einer-Jensen, N; Makawiti, DW; Oduma, JA; Oduor-Okelo, D; Wango, EO, 1995) |
| "Adult female Sprague-Dawley rats were injected with 5 or 20 mg/kg body weight heptachlor solution every other day for up to 18 days." | 3.69 | Effects of graded doses of the pesticide heptachlor on body weight, mating success, oestrous cycle, gestation length and litter size in laboratory rats. ( Einer-Jensen, N; Makawiti, DW; Oduma, JA; Oduor-Okelo, D; Wango, EO, 1995) |
| "Heptachlor has been targeted for global elimination because of its toxicity and environmental persistence, in accordance with the Stockholm Convention on Persistent Organic Pollutants (POPs)." | 1.46 | Effects on the reproductive parameters of two generations of Rattus norvegicus offspring from dams exposed to heptachlor during gestation and lactation. ( Cerbón, M; Martínez-Ibarra, A; Morimoto, S; Prado-Flores, G, 2017) |
| "Heptachlor is a cyclodiene pesticide that was widely used for many years, and for which inadvertent exposure to children and fetuses took place in the early 1980s; yet little is known regarding the developmental neurotoxicity of it and other cyclodienes." | 1.31 | Neurotoxicological outcomes of perinatal heptachlor exposure in the rat. ( Chapin, RE; Harris, MW; Meacham, CA; Moser, VC; Shafer, TJ; Ward, TR, 2001) |
| " Time-bred pregnant female Sprague-Dawley rats were dosed by gavage with H (0, 30, 300, or 3000 microg/kg/day) from gestation day (GD) 12 to postnatal day (PND) 7, followed by direct dosing of the pups with H through PND 42." | 1.31 | The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats. ( Chapin, RE; Copeland, CB; Davis, BJ; Harris, MW; Overstreet, D; Smialowicz, RJ; Williams, WC, 2001) |
| "Heptachlor is a persistent cyclodiene pesticide that affects GABAergic function." | 1.31 | Dopamine transporter binding in the rat striatum is increased by gestational, perinatal, and adolescent exposure to heptachlor. ( McDaniel, KL; Moser, VC; Purkerson-Parker, S, 2001) |
| "Exposure of the cyclodiene insecticide heptachlor at 1/8 and 1/4 LD50 to male and female albino rats before mating affected fertility in both sexes." | 1.29 | Prenatal toxicity of heptachlor in albino rats. ( Krishnakumari, MK; Rani, BE, 1995) |
| "5 kg BW) were dosed (i." | 1.27 | Elimination of [14C]heptachlor from body stores of lactating ewes treated with ovine growth hormone. ( Hallford, DM; Holcombe, DW; Khan, MF; Rozman, K; Smith, GS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (41.38) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, Y | 1 |
| Yin, S | 1 |
| Zhang, J | 1 |
| Guo, F | 1 |
| Aamir, M | 1 |
| Liu, S | 1 |
| Liu, K | 1 |
| Liu, W | 1 |
| Martínez-Ibarra, A | 1 |
| Morimoto, S | 1 |
| Cerbón, M | 1 |
| Prado-Flores, G | 1 |
| Wrobel, MH | 1 |
| Mlynarczuk, J | 1 |
| Richardson, JR | 1 |
| Caudle, WM | 1 |
| Wang, MZ | 1 |
| Dean, ED | 1 |
| Pennell, KD | 1 |
| Miller, GW | 1 |
| Ibarluzea, J | 1 |
| Alvarez-Pedrerol, M | 1 |
| Guxens, M | 1 |
| Marina, LS | 1 |
| Basterrechea, M | 1 |
| Lertxundi, A | 1 |
| Etxeandia, A | 1 |
| Goñi, F | 1 |
| Vioque, J | 1 |
| Ballester, F | 1 |
| Sunyer, J | 1 |
| Souza, MS | 1 |
| Magnarelli de Potas, G | 1 |
| Pechén de D'Angelo, AM | 1 |
| Lawson, G | 1 |
| Luderer, U | 1 |
| Wang, D | 1 |
| Atkinson, S | 1 |
| Hoover-Miller, A | 1 |
| Lee, SE | 1 |
| Li, QX | 1 |
| Jensen, AA | 1 |
| Mussalo-Rauhamaa, H | 1 |
| Pyysalo, H | 1 |
| Moilanen, R | 1 |
| Dickson, J | 1 |
| Peet, RL | 1 |
| Duffy, RJ | 1 |
| Bolton, J | 1 |
| Hilbert, B | 1 |
| McGill, C | 1 |
| Oduma, JA | 1 |
| Wango, EO | 1 |
| Makawiti, DW | 1 |
| Einer-Jensen, N | 1 |
| Oduor-Okelo, D | 1 |
| Rani, BE | 1 |
| Krishnakumari, MK | 1 |
| Crum, JA | 1 |
| Bursian, SJ | 1 |
| Aulerich, RJ | 1 |
| Polin, D | 1 |
| Braselton, WE | 1 |
| Narotsky, MG | 1 |
| Weller, EA | 1 |
| Chinchilli, VM | 1 |
| Kavlock, RJ | 1 |
| Dello Iacovo, R | 1 |
| Celentano, E | 1 |
| Strollo, AM | 1 |
| Iazzetta, G | 1 |
| Capasso, I | 1 |
| Randazzo, G | 1 |
| Moser, VC | 2 |
| Shafer, TJ | 1 |
| Ward, TR | 1 |
| Meacham, CA | 1 |
| Harris, MW | 2 |
| Chapin, RE | 2 |
| Smialowicz, RJ | 1 |
| Williams, WC | 1 |
| Copeland, CB | 1 |
| Overstreet, D | 1 |
| Davis, BJ | 1 |
| Purkerson-Parker, S | 1 |
| McDaniel, KL | 1 |
| Downey, WK | 1 |
| Flynn, MP | 1 |
| Aherne, SA | 1 |
| Jonsson, V | 1 |
| Liu, GJ | 1 |
| Armbruster, J | 1 |
| Kettelhut, LL | 1 |
| Drucker, B | 1 |
| Arnold, DW | 1 |
| Kennedy, GL | 1 |
| Keplinger, ML | 1 |
| Calandra, JC | 1 |
| Calo, CJ | 1 |
| Holcombe, DW | 1 |
| Smith, GS | 1 |
| Khan, MF | 1 |
| Hallford, DM | 1 |
| Rozman, K | 1 |
| Petterson, DS | 1 |
| Casey, RH | 1 |
| Ebell, GF | 1 |
| McIntyre, BL | 1 |
| Yamaguchi, M | 1 |
| Tanaka, S | 1 |
| Kawashima, K | 1 |
| Nakaura, S | 1 |
| Takanaka, A | 1 |
| Macklin, AW | 1 |
| Ribelin, WE | 1 |
| Wassermann, M | 2 |
| Tomatis, L | 2 |
| Wassermann, D | 2 |
| Day, NE | 1 |
| Groner, Y | 1 |
| Lazarovici, S | 1 |
| Rosenfeld, D | 1 |
| Nogueira, DP | 1 |
| Athie, E | 1 |
| Djavaherian, M | 1 |
| Guttel, C | 1 |
2 reviews available for heptachlor and Pregnancy
| Article | Year |
|---|---|
Chemical contaminants in human milk.
Topics: Adult; Aldrin; Body Burden; Breast Feeding; DDT; Dieldrin; Environmental Pollutants; Female; Heptach | 1983 |
Chlordane and heptachlor.
Topics: Air Pollutants, Occupational; Animals; Carcinogenicity Tests; Case-Control Studies; Chlordan; Cocarc | 1991 |
27 other studies available for heptachlor and Pregnancy
| Article | Year |
|---|---|
Exposure patterns, chemical structural signatures, and health risks of pesticides in breast milk: A multicenter study in China.
Topics: Canada; China; Dichlorodiphenyl Dichloroethylene; Environmental Monitoring; Female; Heptachlor; Hexa | 2022 |
Effects on the reproductive parameters of two generations of Rattus norvegicus offspring from dams exposed to heptachlor during gestation and lactation.
Topics: Animals; Cervix Uteri; Endocrine Disruptors; Estrogen Receptor alpha; Female; Heptachlor; Immunohist | 2017 |
Secretory function of ovarian cells and myometrial contractions in cow are affected by chlorinated insecticides (chlordane, heptachlor, mirex) in vitro.
Topics: Animals; Cattle; Chlordan; Female; Heptachlor; In Vitro Techniques; Insecticides; Mirex; Ovary; Preg | 2017 |
Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner.
Topics: Analysis of Variance; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Plasma M | 2008 |
Sociodemographic, reproductive and dietary predictors of organochlorine compounds levels in pregnant women in Spain.
Topics: Adult; Demography; Dichlorodiphenyl Dichloroethylene; Diet; Environmental Pollutants; Female; Heptac | 2011 |
Organophosphorous and organochlorine pesticides affect human placental phosphoinositides metabolism and PI-4 kinase activity.
Topics: 1-Phosphatidylinositol 4-Kinase; Azinphosmethyl; Cells, Cultured; Chlorpyrifos; DDT; Female; Heptach | 2004 |
Gestational and lactational exposure to heptachlor does not alter reproductive system development in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Heptachlor; Insecticides; Lactation; Male; Organ | 2004 |
Organochlorines in harbor seal (Phoca vitulina) tissues from the northern Gulf of Alaska.
Topics: Adipose Tissue; Alaska; Animals; Animals, Newborn; Body Burden; Body Weight; DDT; Environmental Expo | 2007 |
Influence of diet and other factors on the levels of organochlorine compounds in human adipose tissue in Finland.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Aged; Animals; Breast Feeding; Child; Child, Prescho | 1984 |
Heptachlor poisoning in horses and cattle.
Topics: Abortion, Veterinary; Animals; Cattle; Cattle Diseases; Female; Heptachlor; Heptachlor Epoxide; Hors | 1984 |
Effects of graded doses of the pesticide heptachlor on body weight, mating success, oestrous cycle, gestation length and litter size in laboratory rats.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estrus; Female; Gestational Age; Heptachlor; | 1995 |
Prenatal toxicity of heptachlor in albino rats.
Topics: Animals; Dose-Response Relationship, Drug; Estrogens; Female; Fertility; Heptachlor; Humans; Male; O | 1995 |
The reproductive effects of dietary heptachlor in mink (Mustela vison).
Topics: Animals; Animals, Newborn; Body Burden; Body Weight; Eating; Female; Heptachlor; Lethal Dose 50; Mal | 1993 |
Nonadditive developmental toxicity in mixtures of trichloroethylene, Di(2-ethylhexyl) phthalate, and heptachlor in a 5 x 5 x 5 design.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Diethylhexyl Phthalate; Drug Interactions; Embry | 1995 |
Organochlorines and breast cancer. A study on Neapolitan women.
Topics: Adipose Tissue; Breast Neoplasms; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; Fe | 1999 |
Neurotoxicological outcomes of perinatal heptachlor exposure in the rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Chlorides; Embryon | 2001 |
The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats.
Topics: Animals; Animals, Newborn; Antibody Formation; Body Weight; Dose-Response Relationship, Drug; Enzyme | 2001 |
Dopamine transporter binding in the rat striatum is increased by gestational, perinatal, and adolescent exposure to heptachlor.
Topics: Animals; Behavior, Animal; Binding, Competitive; Corpus Striatum; Dopamine Plasma Membrane Transport | 2001 |
Organochlorine content of milks, dairy products and animal feed ingredients: Ireland 1971-1972.
Topics: Aldrin; Animal Feed; Animals; Cattle; Dairy Products; DDT; Dieldrin; Female; Heptachlor; Hexachloroc | 1975 |
Chlorohydrocarbon pesticide residues in human milk in Greater St. Louis, Missouri 1977.
Topics: DDT; Dichlorodiphenyl Dichloroethylene; Dieldrin; Female; Food Contamination; Heptachlor; Heptachlor | 1977 |
Dominant lethal studies with technical chlordane, HCS-3260, and heptachlor: heptachlor epoxide.
Topics: Animals; Chlordan; Diet; Embryo, Mammalian; Female; Genes, Dominant; Genes, Lethal; Heptachlor; Hept | 1977 |
Elimination of [14C]heptachlor from body stores of lactating ewes treated with ovine growth hormone.
Topics: Animals; Body Burden; Female; Growth Hormone; Heptachlor; Lactation; Pregnancy; Sheep | 1988 |
Residues in beef cattle accidentally exposed to commercial heptachlor.
Topics: Adipose Tissue; Animals; Cattle; Chlordan; Diet; Female; Heptachlor; Heptachlor Epoxide; Lactation; | 1988 |
[Effects of heptachlor on fetal developments of rats].
Topics: Administration, Oral; Animals; Body Weight; Eating; Embryonic and Fetal Development; Female; Heptach | 1987 |
The relation of pesticides to abortion in dairy cattle.
Topics: Abortion, Veterinary; Adipose Tissue; Aldrin; Animal Feed; Animals; Animals, Newborn; Cattle; Cattle | 1971 |
Epidemiology of organochlorine insecticides in the adipose tissue of Israelis.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Aged; Autopsy; Child; Child, Preschool; Chromatograp | 1974 |
Storage of organochlorine insecticides in people of Sao Paulo, Brazil.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Brazil; Child; Child, Preschool; Chromatography, Gas | 1972 |