heptachlor has been researched along with Encephalopathy, Toxic in 3 studies
Heptachlor: A man-made compound previously used to control termites and other insects. Even though production of heptachlor was phased out of use in the United States during the late 1980's it remains in soil and hazardous waste sites. It is clearly toxic to animals and humans but, the International Agency for Research on Cancer (IARC) has determined that heptachlor is not classifiable as to its carcinogenicity to humans. (From ATSDR Public Heath Statement, April 1989)
heptachlor : A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the compound induced Parkinsonism-like movement deficits when assessed by a gait and a pole test." | 1.40 | Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice. ( Hong, S; Hwang, J; Kang, SJ; Kim, JY; Shin, KS, 2014) |
| " Significant increase in V(max) of striatal DAT was not observed at doses > 12 mg/kg, which suggested that toxic effects of heptachlor epoxide may be responsible for loss of maximal dopamine uptake observed at higher doses of heptachlor." | 1.31 | Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways. ( Barlow, RL; Bloomquist, JR; Kirby, ML, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, S | 1 |
| Hwang, J | 1 |
| Kim, JY | 1 |
| Shin, KS | 1 |
| Kang, SJ | 1 |
| Kirby, ML | 1 |
| Barlow, RL | 1 |
| Bloomquist, JR | 1 |
3 other studies available for heptachlor and Encephalopathy, Toxic
| Article | Year |
|---|---|
Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice.
Topics: Animals; Apoptosis; Astrocytes; Cell Line, Tumor; Cells, Cultured; Dopaminergic Neurons; Gait; Hepta | 2014 |
Infant and child neurotoxicity studies: subtle and long-term effects. Focusing on methylmercury, PCBs, heptachlor and other persistent pollutants. Abstracts from the 21st International Neurotoxicology Conference. February 10-14, 2002, Honolulu, Hawaii, US
Topics: Child; Environmental Pollutants; Heptachlor; Humans; Infant; Methylmercury Compounds; Neurotoxicity | 2004 |
Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways.
Topics: Animals; Cell Membrane; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Heptachlor; In | 2001 |