heptachlor has been researched along with Delayed Effects, Prenatal Exposure in 6 studies
Heptachlor: A man-made compound previously used to control termites and other insects. Even though production of heptachlor was phased out of use in the United States during the late 1980's it remains in soil and hazardous waste sites. It is clearly toxic to animals and humans but, the International Agency for Research on Cancer (IARC) has determined that heptachlor is not classifiable as to its carcinogenicity to humans. (From ATSDR Public Heath Statement, April 1989)
heptachlor : A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heptachlor has been targeted for global elimination because of its toxicity and environmental persistence, in accordance with the Stockholm Convention on Persistent Organic Pollutants (POPs)." | 1.46 | Effects on the reproductive parameters of two generations of Rattus norvegicus offspring from dams exposed to heptachlor during gestation and lactation. ( Cerbón, M; Martínez-Ibarra, A; Morimoto, S; Prado-Flores, G, 2017) |
| "Heptachlor is a cyclodiene pesticide that was widely used for many years, and for which inadvertent exposure to children and fetuses took place in the early 1980s; yet little is known regarding the developmental neurotoxicity of it and other cyclodienes." | 1.31 | Neurotoxicological outcomes of perinatal heptachlor exposure in the rat. ( Chapin, RE; Harris, MW; Meacham, CA; Moser, VC; Shafer, TJ; Ward, TR, 2001) |
| " Time-bred pregnant female Sprague-Dawley rats were dosed by gavage with H (0, 30, 300, or 3000 microg/kg/day) from gestation day (GD) 12 to postnatal day (PND) 7, followed by direct dosing of the pups with H through PND 42." | 1.31 | The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats. ( Chapin, RE; Copeland, CB; Davis, BJ; Harris, MW; Overstreet, D; Smialowicz, RJ; Williams, WC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martínez-Ibarra, A | 1 |
| Morimoto, S | 1 |
| Cerbón, M | 1 |
| Prado-Flores, G | 1 |
| Richardson, JR | 1 |
| Caudle, WM | 1 |
| Wang, MZ | 1 |
| Dean, ED | 1 |
| Pennell, KD | 1 |
| Miller, GW | 1 |
| Lawson, G | 1 |
| Luderer, U | 1 |
| Moser, VC | 1 |
| Shafer, TJ | 1 |
| Ward, TR | 1 |
| Meacham, CA | 1 |
| Harris, MW | 2 |
| Chapin, RE | 2 |
| Smialowicz, RJ | 1 |
| Williams, WC | 1 |
| Copeland, CB | 1 |
| Overstreet, D | 1 |
| Davis, BJ | 1 |
1 review available for heptachlor and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Chlordane and heptachlor.
Topics: Air Pollutants, Occupational; Animals; Carcinogenicity Tests; Case-Control Studies; Chlordan; Cocarc | 1991 |
5 other studies available for heptachlor and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Effects on the reproductive parameters of two generations of Rattus norvegicus offspring from dams exposed to heptachlor during gestation and lactation.
Topics: Animals; Cervix Uteri; Endocrine Disruptors; Estrogen Receptor alpha; Female; Heptachlor; Immunohist | 2017 |
Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner.
Topics: Analysis of Variance; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Plasma M | 2008 |
Gestational and lactational exposure to heptachlor does not alter reproductive system development in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Heptachlor; Insecticides; Lactation; Male; Organ | 2004 |
Neurotoxicological outcomes of perinatal heptachlor exposure in the rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Chlorides; Embryon | 2001 |
The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats.
Topics: Animals; Animals, Newborn; Antibody Formation; Body Weight; Dose-Response Relationship, Drug; Enzyme | 2001 |