heparitin-sulfate and Epilepsies--Myoclonic

heparitin-sulfate has been researched along with Epilepsies--Myoclonic* in 2 studies

Other Studies

2 other study(ies) available for heparitin-sulfate and Epilepsies--Myoclonic

ArticleYear
[Myoclonus epilepsy in children and adolescents].
    Sovetskaia meditsina, 1991, Issue:12

    Twelve cases of myoclonus epilepsy initiating in childhood and adolescence were studied clinically, electrophysiologically and biochemically. Myoclonic and epileptic syndromes being most pronounced, the clinical pattern presented certain polymorphism: asymmetry, hyperkinesis, myodystonia, epileptic episodes, mental disorders. The electroencephalographic picture of the disease was variable. Hyperexcretion of glycosaminoglycans and changes in their fraction composition with predominant release of heparan sulphate evidenced for deranged metabolism of mucopolysaccharides.

    Topics: Adolescent; Age Factors; Child; Diagnosis, Differential; Epilepsies, Myoclonic; Glycosaminoglycans; Heparitin Sulfate; Humans

1991
Content and composition of urinary glycosaminoglycans in the patients with myoclonus epilepsy with and without Lafora bodies.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:4

    Content, composition and molecular weight distribution of the urinary glycosaminoglycans (GAG) were determined in five patients with progressive myoclonus epilepsy (PME). In one patient (Family B) this syndrome was associated with cerebral Lafora bodies and in four siblings of Family A, no Lafora bodies were present in brain biopsy. Only one of the five patients had a moderate increase of urinary GAG excretion as expressed by 24-h output or creatinine. The heparan sulfate component of the GAG was moderately increased in two other patients. The molecular weight distribution of the urinary GAG was normal. The results do not support the contention that urinary GAG excretion is abnormal in PME. Among nine lysosomal enzymes in leucocytes, only the activity of alpha-mannosidase was increased 3-fold in the four siblings.

    Topics: Adolescent; Adult; Brain; Chondroitin Sulfates; Creatinine; Dermatan Sulfate; Epilepsies, Myoclonic; Female; Glycosaminoglycans; Heparitin Sulfate; Humans; Hyaluronic Acid; Inclusion Bodies; Leukocytes; Lysosomes; Male; Mannosidases

1977