heparitin-sulfate and Arenaviridae-Infections

heparitin-sulfate has been researched along with Arenaviridae-Infections* in 1 studies

Other Studies

1 other study(ies) available for heparitin-sulfate and Arenaviridae-Infections

Article	Year
Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan. Journal of virology, 2018, 03-01, Volume: 92, Issue:5 Fatal infection with the highly pathogenic Lassa virus (LASV) is characterized by extensive viral dissemination, indicating broad tissue tropism. The major cellular receptor for LASV is the highly conserved extracellular matrix receptor dystroglycan (DG). Binding of LASV depends on DG's tissue-specific posttranslational modification with the unusual O-linked polysaccharide matriglycan. Interestingly, functional glycosylation of DG does not always correlate with viral tropism observed Topics: A549 Cells; Antiviral Agents; Arenaviridae Infections; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Dystroglycans; Endosomes; Gene Expression; Glycosylation; HEK293 Cells; HeLa Cells; Heparitin Sulfate; Humans; Lassa virus; Lymphocytic choriomeningitis virus; Lysosomal Membrane Proteins; Pinocytosis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Virus; RNA Interference; Signal Transduction; Tropism; Virus Attachment; Virus Internalization	2018

Article

Year

Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan.

Journal of virology, 2018, 03-01, Volume: 92, Issue:5

Fatal infection with the highly pathogenic Lassa virus (LASV) is characterized by extensive viral dissemination, indicating broad tissue tropism. The major cellular receptor for LASV is the highly conserved extracellular matrix receptor dystroglycan (DG). Binding of LASV depends on DG's tissue-specific posttranslational modification with the unusual O-linked polysaccharide matriglycan. Interestingly, functional glycosylation of DG does not always correlate with viral tropism observed

Topics: A549 Cells; Antiviral Agents; Arenaviridae Infections; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Dystroglycans; Endosomes; Gene Expression; Glycosylation; HEK293 Cells; HeLa Cells; Heparitin Sulfate; Humans; Lassa virus; Lymphocytic choriomeningitis virus; Lysosomal Membrane Proteins; Pinocytosis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Virus; RNA Interference; Signal Transduction; Tropism; Virus Attachment; Virus Internalization

2018