heme has been researched along with Porphyrias in 458 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 327 (71.40) | 18.7374 |
| 1990's | 58 (12.66) | 18.2507 |
| 2000's | 33 (7.21) | 29.6817 |
| 2010's | 35 (7.64) | 24.3611 |
| 2020's | 5 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Larmann, J; Lederer, D; Weigand, MA | 1 |
| Testai, FD; Wylie, K | 1 |
| Dailey, HA; Medlock, AE | 1 |
| Balwani, M; Keel, S; Yasuda, M | 1 |
| To-Figueras, J | 1 |
| Ali Khan, S; Gandhi, J; Jiang, W; Joshi, G; Seyam, O; Smith, NL; Suh, Y | 1 |
| Cox, P; Huynh, N; King-Jones, K; Lill, R; Ou, Q | 1 |
| Allaf, B; Gil, S; Gouya, L; Lefebvre, T; Manceau, H; Muller, F; Peoc'h, K; Puy, H; Puy, V; Rosenblatt, J; Schmitt, CM | 1 |
| Kakoullis, L; Louppides, S; Panos, G; Papachristodoulou, E | 1 |
| Chen, B; Desnick, RJ; Yasuda, M | 1 |
| Cuny, JF | 1 |
| Daher, R; Gouya, L; Karim, Z; Lefebvre, T; Mirmiran, A; Nicolas, G; Peoc'h, K; Puy, H; Schmitt, C | 1 |
| Basrur, V; Carter, EL; Herrmann, H; Lehnert, N; Maitra, D; Nesvizhskii, AI; Omary, MB; Osawa, Y; Ragsdale, SW; Richardson, R; Rittié, L; Wolf, MW; Zhang, H | 1 |
| Bonkovsky, HL; Bragazzi Cunha, J; Elenbaas, JS; Maitra, D; Omary, MB; Shavit, JA | 1 |
| Phillips, JD | 1 |
| Bonkovsky, HL; Guo, JT; Hou, W; Li, T; Narang, T; Thapar, M | 1 |
| Anderson, SA; Boyer, LF; Chen, MJ; Chen, W; Chung, J; Datta, S; Deck, KM; Eisenstein, RS; Galy, B; Gwynn, B; Hentze, MW; Huston, NC; Kaplan, J; Lambert, AJ; Langer, NB; Li, L; Lu, W; Paradkar, PN; Paw, BH; Peters, LL; Sahr, K; Schlaeger, TM; Shaw, GC; Ward, DM; Wei, Z; Wittig, JG | 1 |
| Imhof, D; Kühl, T | 1 |
| Lund, C; Schjelde, S | 1 |
| Brock, A; Hertz, JM; Rasmussen, LM | 1 |
| Nascimbeni, F; Rocchi, E; Roveri, G; Ventura, P | 1 |
| Frank, J | 1 |
| Deybach, JC; Gouya, L; Martin-Schmitt, C; Peoc'h, K; Puy, H; Talbi, N | 1 |
| Deybach, JC; Gouya, L; Puy, H | 1 |
| Bond, PJ; Brighton, C; Cheong, PL; Ford, RC; Frase, S; Fukuda, Y; Kargas, V; Lynch, J; Ney, PA; Rampersaud, E; Sankaran, VG; Schuetz, JD; Trent, RJ; Vogel, P; Wang, Y; Weiss, MJ; Yu, B | 1 |
| Bonkovsky, HL; Flotte, TJ; Hedley-Whyte, ET; Roig, Z; Siao, P | 1 |
| Besana, V; Brancaleoni, V; Cappellini, MD; Di Pierro, E | 1 |
| Frank, J; Poblete-Gutiérrez, P; van Serooskerken, AM | 1 |
| Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I | 1 |
| Choiniere, JR; Gelb, MH; Scott, CR; Turecek, F | 1 |
| Pietrangelo, A | 1 |
| Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D | 1 |
| Kushner, JP; Phillips, JD | 2 |
| Bruchajzer, E | 1 |
| Bonkovsky, HL; Hou, W; Li, T; Schrum, LW; Tian, Q; Zheng, J | 1 |
| Herkes, GK; Simon, NG | 1 |
| Iwadate, R; Kawai, H; Kawashima, Y; Kudo, N; Mashino, T; Mitsumoto, A; Satoh, Y; Watanabe, Y | 1 |
| Chavan, H; Krishnamurthy, P | 1 |
| Balwani, M; Desnick, RJ | 2 |
| Benton, CM; Lim, CK | 1 |
| Bruchajzer, E; Frydrych, B; Szymańska, JA | 1 |
| Ahmed, I | 1 |
| Deybach, JC; Doss, M; Doss, MO; Gross, U; Lamoril, J; Meissauer, U; Nordmann, Y; Puy, H | 1 |
| Fujita, H; Nishitani, C; Ogawa, K | 1 |
| Biolcati, G; Cappellini, MD; Danielli, MG; Di Pierro, E; Martinez di Montemuros, F; Patti, E; Rocchi, E; Tavazzi, D | 1 |
| Karpova, IV; Luchinina, IuA; Luk'ianenko, AV; Pivnik, AV; Pustovoĭt, IaS; Surin, VL | 1 |
| BRUGSCH, J | 2 |
| FIGEN, JF; SCHMID, R; SCHWARTZ, S | 1 |
| HANAWA, Y; LABBE, RF; LOTTSFELDT, FI | 1 |
| HEILMEYER, L | 3 |
| PORTER, FS | 1 |
| SCHMID, R | 1 |
| DOWDLE, EB | 1 |
| FINDLAY, GH | 1 |
| LEE, GR | 1 |
| DOGRAMACI, I | 1 |
| WINTERHALTER, KH | 2 |
| CANIVET, J | 1 |
| ALDRICH, RA; LABBE, RF; LOTTSFELDT, FI | 1 |
| Batlle, A; Buzaleh, AM; de Salamanca, RE; Fontanellas, A; García-Bravo, M; Méndez, M; Morán-Jimenez, MJ; Navarro, S | 1 |
| RIMINGTON, C | 4 |
| Gerard, J; Scheen, AJ | 1 |
| Hon, T; Sengupta, A; Zhang, L | 1 |
| Dombeck, TA; Satonik, RC | 1 |
| Li, D | 1 |
| Chin, S; Handschin, C; Lin, J; Meyer, UA; Peyer, AK; Rhee, J; Spiegelman, BM; Wu, PH | 1 |
| Florkowski, C; George, P; Potter, H; Sies, C | 1 |
| Bonkovsky, HL | 2 |
| Frank, J; Merk, HF; Poblete-Gutiérrez, P; Wiederholt, T | 1 |
| Sassa, S | 2 |
| Akagi, R | 1 |
| Akagi, R; Inoue, R | 1 |
| Gatti, P; Gelb, MH; Sadílek, M; Scott, CR; Turecek, F; Wang, Y | 1 |
| Gelb, MH; Scott, CR; Turecek, F; Wang, Y | 1 |
| Heinemann, IU; Jahn, D; Jahn, M | 1 |
| Bonkovsky, HL; Hou, W; Schrum, LW; Tian, Q; Watts, JA; Zheng, J | 1 |
| Coburn, RF; Goldwein, MI; Rother, ML; Shafer, BC; White, P; Williams, WJ | 1 |
| Granick, S; Kappas, A | 2 |
| Brodie, MJ; Goldberg, A; Macphee, GJ; Moore, MR; Philip, MF; Rapeport, WG; Thompson, GG; Yeung Laiwah, AA | 1 |
| Koenig, HM; Marsh, WL | 1 |
| Debets, FM; Hamers, WJ; Strik, JJ | 1 |
| Badawy, AA | 2 |
| Adrien, A; Guillet, G | 1 |
| Goldberg, A; McColl, KE | 1 |
| Iveson-Iveson, J | 1 |
| Friedland, ML; Ibraham, NG; Levere, RD | 1 |
| Bilinski, T; Labbe-Bois, R; Rytka, J | 1 |
| Cole, SP; Marks, GS | 1 |
| Goldberg, A; McColl, KE; Moore, MR | 2 |
| Alexopoulos, J; Cummins, R; Kramer, S; Viljoen, DJ | 1 |
| Magnus, IA | 1 |
| Petersen, JM; Pierach, CA | 1 |
| Gregor, A; Kostrzewska, E; Medrzejewski, W; Michalak, T; Ostrowski, J; Zawirska, B | 1 |
| Correia, MA; Litman, DA | 2 |
| Caimi, G; Catania, A | 1 |
| Alvares, AP; Eiseman, JL; Foidart, M; Muller-Eberhard, U | 1 |
| Atsmon, A; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N | 1 |
| Bonkowsky, HL; Schady, W | 1 |
| Pierach, CA | 2 |
| Pimstone, NR | 1 |
| Elder, GH | 5 |
| Goldberg, A; McColl, KE; Moore, MR; Thompson, GG | 3 |
| Grundy, SM; Liem, HH; McCormack, LR; Muller-Eberhard, U; Strum, WB | 1 |
| Cole, SP; Marks, GS; Zelt, DT | 1 |
| Cohen, I; Glueck, R; Green, D; Ts'ao, CH | 1 |
| King, LE; Quiroz-Kendall, E; Wilson, FA | 1 |
| Goldberg, A; Laiwah, AC; Moore, MR | 1 |
| Bickers, DR | 3 |
| Romeo, G | 1 |
| Grandchamp, B; Nordmann, Y | 2 |
| Ostroff, JW | 1 |
| McColl, KE; Moore, R | 1 |
| Kappas, A; Sassa, S | 2 |
| Waldenström, J | 1 |
| Goldberg, A; McColl, KE; Moore, MR; Thompson, GG; Wallace, AM | 1 |
| Ziegler, G | 1 |
| Lithner, F | 2 |
| te Velde, K | 1 |
| Bradley, D; Frykholm, BC; Hruska, RE; Lamon, JM; Silbergeld, EK | 1 |
| Adam, C; Defresne, C; Guilmot-Bruneau, M; Hassoun, A; Saussez-De Temmerman, A; Wery-Follet, B | 1 |
| Poniatowska, M; Stankiewicz, A | 1 |
| Abdelfattach-Gad, M; Denk, H; Kalt, R; Meyer, UA | 1 |
| Cardinal, RA; Pierach, CA | 1 |
| Bloomer, JR | 2 |
| Gidari, AS; Yeung, TC | 1 |
| Dudley, MD; Morris, DL; Pearson, RD | 1 |
| Manabe, S; Wada, O | 1 |
| Bloomer, JR; Brenner, DA | 2 |
| Czarnecki, DB | 1 |
| Lamola, AA; Lamon, JM; Poh-Fitzpatrick, MB | 1 |
| Fuchs, T; Ippen, H | 2 |
| De Matteis, F; Smith, AG | 1 |
| Bossenmaier, I; Cardinal, R; Pierach, CA; Watson, CJ; Weimer, M | 1 |
| Brooker, JD; Elliott, WH; May, BK; Srivastava, G | 1 |
| Brooker, JD; Elliott, WH; Lim, LK; May, BK; Srivastava, G | 1 |
| Blake, D; Ratnaike, S | 1 |
| Ferreira, GC | 1 |
| Harada, K; Kim, Y; Ohmori, S; Tomokuni, K | 1 |
| Bhasker, CR; Bottomley, SS; Cox, TC; Dogra, SC; May, BK; Sadlon, TJ | 1 |
| Jensen, JD; Resnick, SD | 1 |
| Bonkovsky, HL; Cable, EE; Lambrecht, RW; Pepe, JA; Russo, SM | 1 |
| Bissbort, SH; Myburgh, S; Van Brummelen, R | 1 |
| Ellefson, RD; Solberg, LA; Tefferi, A | 1 |
| Moore, MR | 1 |
| Batlle, AM | 1 |
| Grandchamp, B | 1 |
| Fujita, H; Nagai, T | 1 |
| Fuchs, O | 1 |
| Reynolds, NC | 1 |
| Bhootra, K; Bhootra, RK | 1 |
| Bechara, EJ; DeLucia, R; Demasi, M; Penatti, CA | 1 |
| Elder, GH; Hunt, DM; Jay, M; Röhl, JC; Warren, MJ | 1 |
| De Matteis, F; Marks, GS | 1 |
| Bechara, EJ | 1 |
| Anderson, KE; Bissell, DM; Bloomer, JR; Daniell, WE; Ellefson, RD; Franklin, GM; Labbe, RF; Moore, MR; Pierach, CA; Schreiber, WE; Stockbridge, HL; Tefferi, A; Woods, JS | 1 |
| Canepa, ET; Grinstein, M; Llambias, EB; Varone, CL | 1 |
| Bissell, DM; McDonagh, AF | 1 |
| Kondo, M; Yano, Y | 1 |
| Floderus, Y; Harper, P; Henrichson, A; Thunell, S | 1 |
| Brenner, DA; Scarlett, YV | 1 |
| Bogard, C; Deybach, JC | 1 |
| Afonso, SG; Batlle, AM; Enríquez de Salamanca, R | 1 |
| Hift, RJ | 1 |
| Karpova, IV; Pivnik, AV; Pustovoĭt, IaS | 1 |
| Aldonatti, C; Billi de Catabbi, SC; Fernández-Tomé, MC; San Martin de Viale, LC; Sterin-Speziale, NB | 1 |
| Nakayama, K; Ohyama, T; Okui, T; Takasawa, A; Tamura, M; Terai, I | 1 |
| Schüller Pérez, A | 1 |
| Andant, C; Bogard, C; Deybach, JC; Faivre, J; Nordmann, Y; Puy, H; Soulé, JC | 1 |
| Poh-Fitzpatrick, MB | 2 |
| Sakakihara, Y | 1 |
| Aldonatti, C; de Viale, LC | 1 |
| Badminton, MN; Elder, GH | 1 |
| Rifkind, AB | 1 |
| Elder, GH; Evans, JO; Thomas, N | 1 |
| Brodie, MJ; Goldberg, A; Moore, MR | 1 |
| Bennett, M; Frykholm, BC; Lamon, JM; Tschudy, DP | 1 |
| Goldberg, A; McColl, KE; Moore, MR; Thompson, GT | 1 |
| Fischer, PW; Marks, GS; Morgan, RO; Stephens, JK | 1 |
| Brodie, MJ; Goldberg, A; Graham, DJ; McColl, KE; Moore, MR | 1 |
| Bosch, EP; Bossenmaier, I; Cardinal, R; Pierach, CA; Thorson, M | 1 |
| Strik, JJ | 2 |
| Bossenmaier, I; Cardinal, R; Pierach, CA; Watson, CJ | 2 |
| Sassoon, HF | 1 |
| Meyer, UA | 3 |
| Gidari, AS; Levere, RD | 1 |
| Becker, DM; Kramer, S | 1 |
| Walsh, JR | 1 |
| Doss, M | 3 |
| Beale, SI; Granick, S | 1 |
| Druschky, KF; Schaller, KH; Schwanitz, G | 1 |
| Thier, W | 1 |
| Frykholm, BC; Hess, RA; Lamon, JM; Tschudy, DP | 1 |
| Armas Merino, R; Canals, C; Gómez, R; Monsalve, V; Wolff, C | 1 |
| Brodie, MJ; Goldberg, A; Hardie, RA; Hunter, JA; McColl, KE; Moore, MR; Thompson, GG | 1 |
| Becker, DM; Bernstein, R; Cayanis, E; Dawson, B; Kramer, S; Viljoen, DJ | 1 |
| De Matteis, F; Gibbs, AH; Tephly, TR | 1 |
| Brezis, M; Epstein, O; Ghanem, J; Morris, D; Weiler-Ravell, D | 1 |
| Bacheschi, LA; de Assis, JL; Do Serro-Azul, LG; Marchiori, PE; Moraes, EC; Scaff, M; Yassuda, N | 1 |
| Becker, DM; Kramer, S; Viljoen, JD | 1 |
| Brodie, MJ; Goldbrrg, A; Holti, G; Moore, MR; Thompson, GG | 1 |
| Araquistain, JM; Garrido Peralta, M; Herrerias, JM; Navarro, F; Pérez Cano, R | 1 |
| Kappas, A; Sassa, S; Zalar, GL | 1 |
| Bossenmaier, I; Cardinal, R; Dhar, GJ; Petryka, ZJ; Watson, CJ | 3 |
| Mustajoki, P | 2 |
| Larter, RA | 1 |
| de Goeij, AF; Dubbelman, TM; Van Steveninck, J | 1 |
| Goerz, G | 1 |
| Goldberg, A; Ippen, H; Moore, MR; Seubert, A; Seubert, S; Thompson, GG | 1 |
| Sinnott, JL | 1 |
| Bickers, DR; Harber, LC; Kappas, A; Keogh, L; Rifkind, AB | 1 |
| Denk, H; Eckerstorfer, R | 1 |
| De Matteis, F; Stonard, M | 1 |
| Beattie, AD; Brodie, MJ; Goldberg, A; Moore, MR; Thompson, GG | 1 |
| Neethling, AC; Percy, VA; Shanley, BC | 1 |
| Becker, DM; Katz, J; Kramer, S; Viljoen, JD | 1 |
| Alvares, AP; Anderson, KE; Fischbein, A; Kappas, A; Kestenbaum, D; Sassa, S | 1 |
| Carstens, M; Louw, M; Neethling, AC; Percy, VA; Shanley, BC | 1 |
| Brodie, MJ; Campbell, BC; Goldberg, A; Meredith, PA; Moore, MR; Thompson, GG | 1 |
| Brodie, MJ; Goldberg, A; Moore, MR; Thompson, GG | 1 |
| Brodie, MJ; Campbell, BC; Goldberg, A; Moore, MR; Thompson, GG | 1 |
| Bossenmaier, I; Cardinal, R; Peterson, A; Watson, CJ | 1 |
| Bossenmaier, I; Cardinal, R; Miyagi, K; Petryka, ZJ; Watson, CJ | 1 |
| Blekkenhorst, GH; Eales, L; Pimstone, NR; Webber, BL | 2 |
| Evans, N; Ferramola, AM; Jackson, AH; Matlin, SA; Ryder, DJ; Sancovich, HA; Smith, SG | 1 |
| Bickers, DR; Harber, LC; Kappas, A; Keogh, L | 1 |
| De Matteis, F | 5 |
| Magnussen, CR; Tschudy, DP; Valsamis, M | 1 |
| Sumner, E | 1 |
| Watson, CJ | 1 |
| Frederickson, EL; Mees, DE | 1 |
| Morrone, G | 1 |
| Bloomer, JR; Bonkowsky, HL; Ebert, PS; Mahoney, MJ | 1 |
| Badawy, AA; Evans, M | 2 |
| DeLeo, VA; Harber, LC; Mathews-Roth, M; Poh-Fitzpatrick, M | 1 |
| Paslin, DA | 1 |
| Himberg, JJ; Mustajoki, P; Tenhunen, R; Tokola, O | 1 |
| Badawy, AA; Morgan, CJ | 1 |
| Alessio, L; Buizza, P; De Panfilis, G; De Vincentiis, A; Ferioli, A; Leali, C; Pasolini, G | 1 |
| Dover, SB; Fitzsimons, E; Graham, A; McColl, KE; Moore, MR | 1 |
| Gerbig, HW; Heigl, F; Jacob, K; Nathrath, W; Pape, GR; Steinbeck, G | 1 |
| Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
| Prasad, AR; Somashekharaiah, BV | 1 |
| Billi de Catabbi, S; Ríos de Molina, MC; San Martín de Viale, LC | 1 |
| Conte, ET; Young, JW | 1 |
| Doss, M; Fujita, H; Hassoun, A; Kappas, A; Mercelis, R; Sassa, S; Verstraeten, L | 1 |
| Bloomer, JR; Hill, HD; Kools, AM; Straka, JG | 1 |
| Gray, TA; Manning, DJ | 1 |
| Bawden, MJ; Bhasker, CR; Cox, TC; May, BK | 1 |
| Goldberg, A; Herrick, AL; McColl, KE; Moore, MR; Wallace, AM | 1 |
| Fitzsimons, EJ; Goldberg, SA; McColl, KE; Moore, MR | 1 |
| Batlle, AM; Enríquez de Salamanca, R | 1 |
| Lauharanta, J; Mustajoki, P; Tenhunen, R; Timonen, K | 1 |
| Tenhunen, R | 2 |
| Cathcart, S; Fisher, BM; Goldberg, A; Herrick, AL; McColl, KE; Moore, MR | 1 |
| Elder, GH; Tovey, JA | 1 |
| Arnold, R; Beckh, K; Blanke, H; Doss, M; Sieg, I; Stellwaag, M | 1 |
| Herrero, C; Lecha, M; Mascaró, JM; Muniesa, AM | 1 |
| Aldonatti, C; San Martín de Viale, LC; Vila, MC | 1 |
| Correia, MA; Lunetta, JM | 1 |
| Doss, MO | 1 |
| Kordac, V; Kozáková, M; Martásek, P | 1 |
| Blake, D; Deacon, MC; Henderson, RW; Rose, IS; St John, DJ; Young, GP | 1 |
| Cook, A; Goldberg, A; Herrick, AL; McColl, KE; Moore, MR | 1 |
| Bloomer, JR; Bonkovsky, HL | 1 |
| Mustajoki, P; Pierach, C; Tenhunen, R; Volin, L | 1 |
| Blanloeil, Y; Deybach, JC; Joyau, M; Nordmann, Y; Portier, D | 1 |
| McColl, KE; Moore, MR | 1 |
| Werman, HA | 1 |
| Galbraith, RA; Kappas, A | 1 |
| Muller-Eberhard, U; Smith, AG; Vincent, SH | 1 |
| James, CA; Mackie, JE; Marks, GS; McCluskey, SA; Riddick, DS | 1 |
| Devars du Mayne, JF | 1 |
| Rios de Molina, MC; San Martin de Viale, LC; Taira, MC | 1 |
| Häkli, H; Luhtala, J; Sievers, G; Tenhunen, R | 1 |
| Brodie, MJ; Goldberg, A; Herrick, A; McColl, KE; McLellan, A; Moore, MR | 1 |
| Lindén, IB; Tenhunen, R; Tokola, O | 2 |
| Silbergeld, EK | 1 |
| Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
| Cerf, M; Devars du Mayne, JF; Deybach, JC; Likforman, J; Nordmann, Y; Phung, L; Tenhunen, R | 1 |
| Bakchine, S; Derouesne, C; Fontaine, B; Laplane, D; Nordmann, Y | 1 |
| Bottomley, SS; Muller-Eberhard, U | 1 |
| Woods, JS | 1 |
| Kordac, V; Martásek, P | 2 |
| Berndt, MC; Furby, FH; Green, D | 1 |
| Evans, DB; Herrick, AL; McColl, KE; Nunez, DJ; Williams, PF | 1 |
| Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Thompson, GG | 1 |
| Billett, HH | 1 |
| Himberg, JJ; Mustajoki, P; Tokola, O | 1 |
| Goldberg, A; Moore, MR; Yeung Laiwah, AC | 1 |
| Davidson, B; Kirsch, RE; Meissner, DM; Meissner, PN; Sturrock, ED | 1 |
| Kappas, A | 2 |
| Fujita, H; Sassa, S; Sugita, O | 1 |
| Galbraith, RA | 1 |
| Orii, Y; Sano, S | 1 |
| Bissell, DM | 1 |
| Jenkins, TM; Weitzman, PD | 1 |
| Goldberg, A; Moore, MR; Yeung-Laiwah, AA | 1 |
| Correia, MA; Litman, DA; Lunetta, JM | 1 |
| Sweeney, GD | 1 |
| Hindmarsh, JT | 1 |
| Borthwick, IA; Elliott, WH; May, BK; Pirola, BA; Srivastava, G | 1 |
| el Omar, E; Goldberg, A; McColl, KE; Moore, MR; Thompson, GG | 1 |
| Alter, BP; Kaye, FJ; Schofield, JM; Weinberg, RS | 1 |
| Ch'ng, SL; Jeyamalar, R | 1 |
| Ríos de Molina, Mdel C; San Martín de Viale, LC; Vila, MC; Wainstok de Calmanovici, R | 1 |
| Batlle, AM; Fukuda, H; Parera, VE; Stella, AM; Wider, E | 1 |
| Köstler, E | 1 |
| Tangerås, A | 1 |
| Bissell, DM; Goetsch, CA | 1 |
| Khanderia, U | 1 |
| Colombi, A; Fait, A; Ferioli, A; Foà, V; Maroni, M | 1 |
| Mustajoki, P; Tenhunen, R; Tokola, O; Volin, L | 1 |
| Cabral, JR; Dinsdale, D; Francis, JE; Manson, MM; Smith, AG | 1 |
| Loftin, EB | 1 |
| Hill, RH | 1 |
| Doss, M; Sixel-Dietrich, F; Verspohl, F | 1 |
| Datta, K; Prasad, AR; Shanker, J | 1 |
| Marks, GS; Racz, WJ; Schneck, DW; Tyrrell, DL | 1 |
| Deppe, WM; Joubert, SM; Shanley, BC; Taljaard, JJ | 2 |
| Gorlin, RJ; Schwartz, S; Trodahl, JN | 1 |
| Joubert, SM; Shanley, BC; Taljaard, JJ | 1 |
| Labbe, RF | 1 |
| Marver, HS; Schmid, R | 1 |
| Goldberg, A; Moore, MR | 1 |
| Meyer, UA; Schmid, R | 2 |
| Dancewicz, AM; Panfil, B | 1 |
| Belcher, RV; Smith, SG | 1 |
| Geller, E; Wetterberg, L; Yuwiler, A | 1 |
| Meuer, UA | 1 |
| Bossenmaier, I; Cardinal, R; Petryka, ZJ; Watson, CJ | 1 |
| Levin, EY | 1 |
| Berk, PD; Bossenmaier, I; Cardinal, RA; Sarkar, D; Schwartz, S; Stephenson, BD; Swaim, WR; Weimer, M | 1 |
| Wiegand, SE | 1 |
| Ho, TT | 1 |
| Jurd, RD; Maclean, N | 1 |
| Crispin, M; Szeinberg, A | 1 |
| Elder, GH; Gray, CH; Nicholson, DC | 1 |
| Nair, PP | 1 |
| Gregor, A; Kostrzewska, E | 1 |
| Bradlow, HL; Granick, S; Kappas, A; Sassa, S | 1 |
| Albahary, C | 1 |
| Aoki, Y; Nakao, K; Takaku, F; Wada, O; Yano, Y | 1 |
| Berk, PD; Berlin, NI; Bloomer, JR; Howe, RB; Jones, EA; Shrager, R | 1 |
| Amrutavalli, J; Padmanaban, G; Rajamanickam, C; Rao, MR | 1 |
| Stich, W | 2 |
| Beattie, DS; Patton, GM | 1 |
| Eisenburg, J | 1 |
| Eriksen, L; Hofstad, F; Seip, M | 1 |
| Abbritti, G; De Matteis, F; Gibbs, AH | 1 |
| Blekkenhorst, G; Eales, L; Pimstone, NR | 1 |
| Iio, A; Liem, HH; Muller-Eberhard, U; Spilberg, I; Wochner, RD | 1 |
| Munteanu, N | 1 |
| Kappas, A; Levere, RD | 1 |
| Takaku, F | 1 |
| Kappas, A; Levere, RD; Pindyck, J | 1 |
| Abbritti, G; De Matteis, F | 1 |
| Manning, J; Marver, HS; Strand, LJ | 2 |
| De Matteis, F; Gibbs, A | 1 |
| Munro, DD; O'Gorman, DJ | 1 |
| Elliott, WH; Whiting, MJ | 1 |
| Anderson, AS; Edmondson, PR; Fusaro, RM; Johnson, JA; Schwartz, S; Stephenson, BD | 1 |
| Berlin, NI; Bloomer, JR; Jones, EA | 1 |
| Clark, KG; Nicholson, DC | 1 |
| Kaneko, JJ; Keeton, KS; Zinkl, JG | 1 |
| Marks, GS; Schneck, DW; Tyrrell, DL | 1 |
| Padmanaban, G; Rao, MR; Sarma, PS | 1 |
| Marver, HS; Meyer, UA | 2 |
| Dowdle, E; French, TJ; Weir, H | 1 |
| Creighton, JM; Marks, GS; Racz, WJ; Schneck, DW; Tyrrell, DL | 1 |
| Martins-Silva, JA; Palma-Carlos, AG; Palma-Carlos, ML | 1 |
| Goodman, JR; Hall, SG | 1 |
| Hammaker, LE; Marver, HS; Sholnick, PL | 1 |
| Felsher, BF; Marver, HS; Redeker, AG; Strand, LJ | 1 |
| Bonkowsky, HL; Bossenmaier, I; Cardinal, R; Collins, A; Doherty, J; Tschudy, DP; Watson, CJ | 1 |
| White, P | 1 |
| Heilmeyer, L; Heilmeyer, LM; Kissel, HJ | 1 |
| Roder, H | 1 |
| Chatterjea, JB; Chatterji, AK | 1 |
| Gibson, SL; Goldberg, A | 1 |
| Kaufman, L; Marver, HS | 1 |
| Jones, MS; Jones, OT | 1 |
| Nicknish, SP; White, CW | 1 |
| Doss, M; Meinhof, W | 1 |
| Onisawa, J | 1 |
| Dowdle, E; Eales, L; Mustard, P; Spong, N | 1 |
| Hanna, M; Hanstein, A; Javid, J; Liem, HH; Muller-Eberhard, U | 1 |
| Jones, CC; Lang, PA; Levine, H; Mills, GC | 1 |
| Granick, S; Kappas, A; Levere, RD | 1 |
| Goldberg, A | 1 |
| Cartwright, GE; Lee, R; Rothstein, G | 1 |
| Chisolm, JJ | 1 |
| Kaneko, JJ; Smith, JE | 2 |
125 review(s) available for heme and Porphyrias
| Article | Year |
|---|---|
Neurological Manifestations of Acute Porphyrias.
Topics: Heme; Humans; Neuralgia; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Posterior Leukoencephalopathy Syndrome | 2022 |
New Avenues of Heme Synthesis Regulation.
Topics: Erythropoiesis; Gene Expression Regulation; Heme; Humans; Porphyrias | 2022 |
Neurological and neuropsychiatric manifestations of porphyria.
Topics: Heme; Humans; Mental Disorders; Nervous System Diseases; Peripheral Nervous System Diseases; Porphyrias | 2019 |
Porphyrias and photosensitivity: pathophysiology for the clinician.
Topics: Heme; Iron; Photosensitivity Disorders; Porphyria Cutanea Tarda; Porphyria, Erythropoietic; Porphyrias; Porphyrins; Protoporphyrins; Uroporphyrins | 2018 |
Recent advances on porphyria genetics: Inheritance, penetrance & molecular heterogeneity, including new modifying/causative genes.
Topics: Biosynthetic Pathways; Gain of Function Mutation; Gene Expression Regulation; Heme; Humans; Loss of Function Mutation; Penetrance; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Protoporphyria, Erythropoietic | 2019 |
[The cutaneous porphyrias].
Topics: Biopsy; Coproporphyria, Hereditary; Diagnosis, Differential; Heme; Humans; Photosensitivity Disorders; Porphyria Cutanea Tarda; Porphyria, Erythropoietic; Porphyrias; Protoporphyria, Erythropoietic; Skin; Skin Diseases, Metabolic | 2019 |
Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anemia, Sideroblastic; Animals; Binding Sites; GATA1 Transcription Factor; Gene Expression Regulation; Heme; Humans; Liver; Mice; Mutation, Missense; Porphyrias; Promoter Regions, Genetic | 2019 |
Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury.
Topics: Animals; Carcinoma, Hepatocellular; Dermatitis, Phototoxic; Heme; Humans; Liver; Liver Neoplasms; Mice; Oxidation-Reduction; Oxidative Stress; Photosensitivity Disorders; Porphyrias; Porphyrins; Protein Aggregates; Protoporphyrins; Uroporphyrins; Zebrafish | 2019 |
Heme biosynthesis and the porphyrias.
Topics: Animals; Biosynthetic Pathways; Environment; Heme; Humans; Liver; Mice; Mutation; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Uroporphyrinogen Decarboxylase | 2019 |
Porphyrin and heme metabolism and the porphyrias.
Topics: Animals; Heme; Heme Oxygenase (Decyclizing); Humans; Porphyrias; Porphyrins | 2013 |
Regulatory Fe(II/III) heme: the reconstruction of a molecule's biography.
Topics: Aging; Anemia; Animals; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Hemolysis; Hemorrhage; Humans; MicroRNAs; Neoplasms; Neurodegenerative Diseases; Porphyrias | 2014 |
[Anaesthetics and porphyria].
Topics: Acute Disease; Anesthetics; Heme; Humans; Porphyrias; Risk Assessment | 2014 |
[Strategies for diagnosis and biochemical control of porphyrias].
Topics: Acute Disease; Heme; Humans; Porphyrias; Porphyrins; Rare Diseases | 2014 |
Drugs and acute porphyrias: reasons for a hazardous relationship.
Topics: Carrier State; Cytochromes; Heme; Humans; Metabolism; Porphyrias; Porphyrias, Hepatic | 2014 |
[Porphyrias and haem related disorders].
Topics: Genetic Diseases, Inborn; Hematologic Diseases; Heme; Humans; Porphyria, Acute Intermittent; Porphyrias | 2016 |
Porphyrias at a glance: diagnosis and treatment.
Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrins | 2010 |
The heme biosynthesis pathway and clinical manifestations of abnormal function.
Topics: Heme; Humans; Porphyrias; Porphyrins | 2001 |
The neurologic manifestations of the acute porphyrias.
Topics: Adult; Female; Heme; Humans; Nervous System Diseases; Peripheral Nerves; Porphyrias; Porphyrins | 2011 |
The porphyrias: advances in diagnosis and treatment.
Topics: Biosynthetic Pathways; Genetic Predisposition to Disease; Heme; Humans; Mutation; Porphyrias | 2012 |
Liquid chromatography and mass spectrometry of haem biosynthetic intermediates: a review.
Topics: Animals; Chromatography, Liquid; Heme; Humans; Mass Spectrometry; Porphyrias | 2012 |
The porphyrias: advances in diagnosis and treatment.
Topics: 5-Aminolevulinate Synthetase; DNA; Erythrocytes; Genes, Recessive; Genetic Therapy; Hematology; Heme; Homozygote; Humans; Metabolism, Inborn Errors; Models, Biological; Mutation; Phlebotomy; Porphyria Cutanea Tarda; Porphyria, Erythropoietic; Porphyrias; Skin; Stem Cells | 2012 |
Childhood porphyrias.
Topics: Child; Heme; Humans; Porphyrias; Porphyrins; Treatment Outcome | 2002 |
PORPHYRIAS AND PORPHYRIN METABOLISM, WITH SPECIAL REFERENCE TO PORPHYRIA IN CHILDHOOD.
Topics: Adrenocorticotropic Hormone; Antifungal Agents; Child; Dermatology; Dimercaprol; Edetic Acid; Enzyme Precursors; Enzymes; Epidemiology; Heme; Humans; Hypertrichosis; Infant; Infant, Newborn; Joint Diseases; Photosensitivity Disorders; Pigmentation Disorders; Porphyrias; Porphyrins; Prednisone; Toxicology; Turkey | 1964 |
[Porphyrias, a rare cause of acute abdominal pain].
Topics: Abdominal Pain; Acute Disease; Heme; Humans; Porphyrias | 2004 |
The porphyrias.
Topics: Adult; Female; Heme; Humans; Porphyrias | 2005 |
Clinical indications for the investigation of porphyria: case examples and evolving laboratory approaches to its diagnosis in New Zealand.
Topics: Adult; Aged, 80 and over; Biomarkers; Child, Preschool; Clinical Laboratory Techniques; Coproporphyria, Hereditary; Female; Heme; Humans; Male; Middle Aged; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyria, Erythropoietic; Porphyria, Variegate; Porphyrias; Porphyrins; Protoporphyria, Erythropoietic | 2005 |
Modern diagnosis and management of the porphyrias.
Topics: Acute Disease; Chronic Disease; Coproporphyria, Hereditary; Heme; Humans; Porphobilinogen Synthase; Porphyria Cutanea Tarda; Porphyria, Erythropoietic; Porphyria, Hepatoerythropoietic; Porphyria, Variegate; Porphyrias; Porphyrias, Hepatic; Protoporphyria, Erythropoietic | 2006 |
[Diversity of physiological functions mediated by heme metabolism].
Topics: Animals; Bilirubin; Heme; Heme Oxygenase (Decyclizing); Humans; Oxidoreductases Acting on CH-CH Group Donors; Point Mutation; Porphobilinogen Synthase; Porphyrias | 2007 |
[Gene defects identified in porphyrias and their participation in onset of this disease].
Topics: 5-Aminolevulinate Synthetase; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Humans; Porphobilinogen Synthase; Porphyrias | 2007 |
The biochemistry of heme biosynthesis.
Topics: Aminolevulinic Acid; Archaea; Bacteria; Heme; Herbicides; Models, Molecular; Neoplasms; Photochemotherapy; Plants; Porphyrias; RNA, Transfer; Tetrapyrroles | 2008 |
The laboratory evaluation of microcytic red blood cells.
Topics: Adolescent; Adult; Anemia; Child; Child, Preschool; Erythrocytes; Erythrocytes, Abnormal; Female; Ferritins; Fetal Hemoglobin; Globins; Hematologic Diseases; Heme; Hemoglobin A2; Hemoglobins; Humans; Infant; Iron; Iron Deficiencies; Lead Poisoning; Male; Models, Biological; Porphyrias; Pregnancy; Thalassemia | 1982 |
Heme metabolism in erythroid and hepatic cells.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrinogen Oxidase; Erythrocytes; Erythropoiesis; Ferrochelatase; Flavoproteins; Heme; Heme Oxygenase (Decyclizing); Humans; Liver; Liver Diseases; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase; Uroporphyrinogen III Synthetase | 1983 |
Ferrochelatase and N-alkylated porphyrins.
Topics: Alkylation; Animals; Ferrochelatase; Heme; Humans; Intracellular Membranes; Lyases; Membrane Lipids; Mitochondria; Mitochondria, Liver; Porphyrias; Porphyrins; Structure-Activity Relationship | 1984 |
The effects of alcohol on porphyrin biosynthesis and metabolism.
Topics: Alcoholism; Anemia; Animals; Ethanol; Heme; Humans; Liver Diseases, Alcoholic; Porphyrias; Porphyrins; Skin Diseases | 1984 |
Neurologic manifestations of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Heme; Humans; Light; Liver Diseases; Muscle Hypotonia; Nerve Fibers; Nerve Fibers, Myelinated; Nervous System Diseases; Pain, Intractable; Peripheral Nerves; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Prognosis; Seizures; Vitamin B 6 Deficiency; Zinc | 1982 |
Hematin therapy for the porphyric attack.
Topics: Catheters, Indwelling; Chemical Phenomena; Chemistry; Drug Administration Schedule; Glucose; Heme; Hemin; Humans; Injections, Intravenous; Kidney; Liver; Porphyrias; Time Factors | 1982 |
Porphyria cutanea tarda.
Topics: Age Factors; Animals; Disease Models, Animal; Erythropoiesis; Heme; Hexachlorobenzene; Humans; Hydrocarbons, Halogenated; Iron; Kidney Failure, Chronic; Liver; Photosensitivity Disorders; Porphyrias; Renal Dialysis; Skin Diseases; Skin Pigmentation; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1982 |
Enzymatic defects in porphyria: an overview.
Topics: 5-Aminolevulinate Synthetase; Animals; Biological Transport; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Erythrocytes; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Liver Diseases; Mitochondria; Porphobilinogen Synthase; Porphyrias; Skin Diseases; Tissue Distribution | 1982 |
The hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Gene Expression Regulation; Heme; Humans; Infant; Liver; Liver Diseases; Male; Middle Aged; Photosensitivity Disorders; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Porphyrins; Prenatal Diagnosis; Protoporphyria, Erythropoietic; Recurrence; Skin Diseases | 1980 |
[Biosynthesis of heme: regulation; hereditary and experimental porphyrias].
Topics: 5-Aminolevulinate Synthetase; Animals; Chemical Phenomena; Chemistry; Enzyme Induction; Erythropoiesis; Heme; Hormones; Humans; Metals; Mitochondria, Liver; Porphyrias; Porphyrins | 1980 |
The effect of ethanol on heme and porphyrin synthesis.
Topics: Alcoholism; Erythropoiesis; Ethanol; Heme; Hemoglobins; Humans; Iron; Porphyrias; Porphyrins; Skin Diseases | 1981 |
The porphyrias: an example of pharmacogenetic disease.
Topics: Acute Disease; Adult; Bloodletting; Drug-Related Side Effects and Adverse Reactions; Female; Heme; Humans; Porphyrias; Pregnancy; Skin Diseases | 1981 |
Genetic, metabolic, and biochemical aspects of the porphyrias.
Topics: Aminolevulinic Acid; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Erythrocytes; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrinogens; Porphyrins; Rodent Diseases; Sciuridae; Swine; Swine Diseases | 1981 |
The porphyrias--a review.
Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Diseases; Male; Porphobilinogen; Porphyrias; Skin Diseases; Time Factors | 1981 |
The diagnosis and follow-up of porphyria.
Topics: Acquired Immunodeficiency Syndrome; Chromatography, High Pressure Liquid; Family Health; Follow-Up Studies; Heme; Hepatitis; Humans; Liver Neoplasms; Porphyrias; Porphyrins | 1995 |
Heme biosynthesis: biochemistry, molecular biology, and relationship to disease.
Topics: Anemia, Sideroblastic; Animals; Enzymes; Genetic Therapy; Heme; Humans; Molecular Biology; Porphyrias | 1995 |
[Metabolic fate of porphyrin and its precursors in porphyria and porphyrinuria].
Topics: Aminolevulinic Acid; Animals; Heme; Humans; Porphyrias; Porphyrins; Protoporphyrins | 1995 |
Molecular regulation of heme biosynthesis in higher vertebrates.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Anemia, Sideroblastic; Animals; Cytochrome P-450 Enzyme System; Erythrocytes; Erythropoiesis; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Humans; Liver; Molecular Sequence Data; Porphyrias; Sequence Homology, Amino Acid; Transcription, Genetic; Vertebrates | 1995 |
Porphyria in childhood.
Topics: Adult; Child; Heme; Humans; Infant; Porphyria Cutanea Tarda; Porphyria, Erythropoietic; Porphyria, Hepatoerythropoietic; Porphyrias | 1995 |
Porphyrias: clinical evaluation and interpretation of laboratory tests.
Topics: Acute Disease; Decision Trees; Diagnosis, Differential; Feces; Heme; Humans; Porphyrias; Porphyrins | 1994 |
Biochemistry of porphyria.
Topics: Acute Disease; Chromosome Mapping; Heme; Humans; Porphyrias; Porphyrins | 1993 |
Porphyrins, porphyrias, cancer and photodynamic therapy--a model for carcinogenesis.
Topics: Aminolevulinic Acid; Heme; Humans; Models, Biological; Neoplasms; Photochemotherapy; Porphyrias; Porphyrins | 1993 |
Molecular genetics of disorders of haem biosynthesis.
Topics: Anemia, Sideroblastic; Genes, Dominant; Genes, Recessive; Heme; Humans; Porphyria, Acute Intermittent; Porphyrias | 1993 |
[Molecular biology of sideroblastic anemia and porphyria].
Topics: Anemia, Sideroblastic; Animals; Dimethyl Sulfoxide; Enzyme Induction; Heme; Liver; Porphyrias; Rats | 1993 |
[The molecular basis and genetics of diseases associated with disorders of heme biosynthesis].
Topics: Anemia, Sideroblastic; Heme; Humans; Molecular Biology; Porphyrias | 1996 |
Cytochrome P450 and its interactions with the heme biosynthetic pathway.
Topics: Animals; Cytochrome P-450 Enzyme System; Griseofulvin; Heme; Liver; Mice; Porphyrias; Rats | 1996 |
Oxidative stress in acute intermittent porphyria and lead poisoning may be triggered by 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Calcium; DNA Damage; Heme; Humans; Iron; Lead Poisoning; Lipid Peroxidation; Mitochondria; Oxidative Stress; Porphyria, Acute Intermittent; Porphyrias; Proteins; Rats; Reactive Oxygen Species | 1996 |
Environmental chemical exposures and disturbances of heme synthesis.
Topics: Environmental Exposure; Environmental Health; Heme; Humans; Hydrocarbons, Halogenated; Lead; Metals; Porphyrias; Porphyrins | 1997 |
[Heme synthesis and its abnormality].
Topics: Heme; Humans; Porphyrias | 1997 |
Porphyria and porphyrinology--the past fifteen years.
Topics: Heme; Humans; Porphyrias | 1998 |
[Introduction to porphyrin and heme].
Topics: Animals; Diagnosis, Differential; Ferrochelatase; Heme; Humans; Mutation; Organ Specificity; Porphobilinogen Synthase; Porphyrias; Porphyrins | 1998 |
Porphyrias.
Topics: Diagnosis, Differential; Enzymes; Genetic Predisposition to Disease; Heme; Humans; Porphyrias | 1998 |
[Porphyrins and porphyrias].
Topics: Animals; Chick Embryo; Child; Female; Heme; Hemochromatosis; Hepatitis C; Heterozygote; Humans; Hydroxymethylbilane Synthase; Iron; Male; Middle Aged; Mutation; Porphyria, Acute Intermittent; Porphyrias; Porphyrins; Retrospective Studies; Transcription, Genetic; Uroporphyrinogen Decarboxylase | 1998 |
The photodynamic and non-photodynamic actions of porphyrins.
Topics: Darkness; Enzymes; Heme; Hemeproteins; Humans; Light; Photosensitizing Agents; Porphyrias; Porphyrins; Protoporphyrins; Reactive Oxygen Species; Skin Diseases; Ultraviolet Rays; Uroporphyrins | 1999 |
[The heme oxygenase system and its physiopathology].
Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Hyperbilirubinemia; Iron; Porphyrias | 1999 |
[Porphyrias].
Topics: Coproporphyrinogen Oxidase; Flavoproteins; Heme; Humans; Hydroxymethylbilane Synthase; Mental Disorders; Mitochondrial Proteins; Mutation; Nervous System Diseases; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen Synthase; Porphyrias; Porphyrins; Prognosis; Protoporphyrinogen Oxidase; Uroporphyrinogen III Synthetase | 2000 |
Management of acute and cutaneous porphyrias.
Topics: Arginine; beta Carotene; Chloroquine; Estrogens; Ethanol; Heme; Humans; Phlebotomy; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyrias; Sunlight | 2002 |
Hormonal effects on the regulation of hepatic heme biosynthesis.
Topics: 1-Methyl-3-isobutylxanthine; 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Androstanes; Animals; Bucladesine; Chick Embryo; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucose; Heme; Hormones; Humans; Hydrocortisone; Insulin; Ketosteroids; Liver; Porphyrias; Porphyrins; Pregnanes; Structure-Activity Relationship; Thyroid Hormones | 1979 |
Enzymatic formation and cellular regulation of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coenzyme A; Coproporphyrinogens; Enzyme Induction; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrins; Uroporphyrinogens | 1977 |
Porphyrin metabolism in porphyria cutanea tarda.
Topics: Feces; Heme; Humans; Liver Diseases; Porphyrias; Porphyrinogens; Porphyrins | 1977 |
The neurological manifestations of porphyria: a review.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Liver; Liver Diseases; Nervous System; Neurologic Manifestations; Peripheral Nerves; Porphobilinogen; Porphyrias; Porphyrins | 1977 |
Hepatic porphyrias. Current concepts.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Coproporphyrinogens; Female; Genetic Diseases, Inborn; Heme; Humans; Liver Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Uroporphyrinogens | 1977 |
[Pathobiochemistry of porphyrias].
Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme; Humans; Liver; Liver Diseases; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins | 1977 |
Use of hematin in the acute attack of the "inducible" hepatic prophyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Female; Heme; Hemin; Humans; Male; Middle Aged; Neurologic Manifestations; Porphobilinogen; Porphyrias; Prognosis | 1978 |
Hemes, chlorophylls, and related compounds: biosynthesis and metabolic regulation.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Bacteria; Chlorophyll; Fungi; Heme; Hemin; Humans; Lead Poisoning; Liver; Methods; Oxygen; Plants; Porphyrias; Porphyrins; Protein Biosynthesis; Protoporphyrins; Uroporphyrinogens | 1978 |
[Chromosome studies in patients with intermittent porphyria].
Topics: Adult; Aminolevulinic Acid; Chromosome Aberrations; Female; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias | 1979 |
[Hematin in the treatment of acute hepatic porphyrias].
Topics: Acute Disease; Heme; Hemin; Humans; Porphyrias | 1979 |
Hepatic porphyrias: new findings on the nature of metabolic defects.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Animals; Erythrocytes; Heme; Humans; Liver; Liver Diseases; Porphyria, Acute Intermittent; Porphyrias; Porphyrins; Rats | 1976 |
The laboratory investigation of the porphyrin disorders: a review.
Topics: Aminolevulinic Acid; Erythropoiesis; Feces; Heme; Humans; Lead Poisoning; Liver; Molecular Conformation; Porphyrias; Porphyrins; Protoporphyrins; Terminology as Topic | 1976 |
The effect of drugs on 5-aminolaevulinate synthetase and other enzymes in the pathway of liver haem biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Animals; Animals, Newborn; Cycloheximide; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Induction; Griseofulvin; Heme; Liver; Microsomes, Liver; Pharmacology; Phenylbutazone; Porphyrias; Porphyrins; Proadifen; Protein Biosynthesis | 1975 |
Acute intermittent porphyria: clinical and selected research aspects.
Topics: Acute Disease; Animals; Estrogens; Female; Heme; History, 19th Century; History, 20th Century; Humans; Nervous System Diseases; Porphyrias | 1975 |
The porphyrias.
Topics: Acute Disease; Heme; Humans; Plasmapheresis; Porphyria, Erythropoietic; Porphyrias; Porphyrias, Hepatic; Porphyrinogens; Porphyrins | 1992 |
Porphyrias and porphyrins.
Topics: Acute Disease; Heme; Humans; Porphyrias; Porphyrins; Skin Diseases; Sunlight | 1991 |
Heme synthesis in protoporphyria.
Topics: Animals; Heme; Humans; Liver Diseases; Photosensitivity Disorders; Porphyrias; Protoporphyria, Erythropoietic; Protoporphyrins | 1991 |
Molecular regulation of 5-aminolevulinate synthase. Diseases related to heme biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Anemia, Sideroblastic; Base Sequence; Heme; Humans; Molecular Sequence Data; Porphyrias | 1990 |
The porphyrias.
Topics: Acute Disease; Heme; Humans; Photochemotherapy; Porphyrias; Skin Diseases | 1990 |
[General considerations on the pathogenesis of porphyria].
Topics: Heme; Humans; Liver Diseases; Porphyrias; Skin Diseases | 1990 |
Heme in the treatment of heme deficiency states.
Topics: Anemia, Sideroblastic; Heme; Humans; Myelodysplastic Syndromes; Porphyrias | 1990 |
The porphyrias.
Topics: Heme; Humans; Liver Diseases; Porphyrias; Porphyrins; Skin Diseases | 1989 |
Heme in the treatment of porphyrias and hematological disorders.
Topics: Hematologic Diseases; Heme; Humans; Porphyrias | 1989 |
[Anesthesia and hepatic porphyria].
Topics: Alcuronium; Anesthesia, General; Anesthetics; Heme; Humans; Liver Diseases; Morphine Derivatives; Porphyrias; Porphyrins; Skin Diseases | 1989 |
Therapy of the acute porphyrias.
Topics: Dietary Carbohydrates; Drug-Related Side Effects and Adverse Reactions; Heme; Humans; Hypertension; Nausea; Pain; Pain Management; Porphyrias; Porphyrins; Seizures; Tachycardia; Vomiting | 1989 |
The porphyrias.
Topics: Acute Disease; Erythropoiesis; Heme; Humans; Liver Diseases; Porphyrias; Skin Diseases | 1989 |
Haem biosynthesis and porphyrias: 50 years in retrospect.
Topics: Biochemistry; Heme; History, 20th Century; Humans; Models, Biological; Porphobilinogen; Porphyrias; Porphyrins; Retrospective Studies | 1989 |
Role of altered heme synthesis in chemical injury to the nervous system.
Topics: Adult; Child; Heme; Humans; Lead Poisoning; Nervous System; Neuroglia; Neurotransmitter Agents; Porphyrias; Porphyrins; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1987 |
Pathophysiology of heme synthesis.
Topics: Adult; Aged; Anemia, Sideroblastic; Female; Heme; Humans; Lead Poisoning; Male; Porphyrias | 1988 |
Enzymes of the heme biosynthesis pathway: recent advances in molecular genetics.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Carboxy-Lyases; Chick Embryo; Cloning, Molecular; DNA; Gene Expression Regulation; Heme; Humans; Hydroxymethylbilane Synthase; Mice; Mutation; Porphobilinogen Synthase; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1988 |
Toxicological aspects of liver heme biosynthesis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; Hexachlorobenzene; Liver; Porphyrias; Protoporphyrins; Rats; Rats, Gunn | 1988 |
Regulation of porphyrin and heme metabolism in the kidney.
Topics: 5-Aminolevulinate Synthetase; Animals; Coproporphyrinogen Oxidase; Ferrochelatase; Heme; Hydrocarbons; Hydroxymethylbilane Synthase; Kidney; Kidney Diseases; Porphobilinogen Synthase; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; Trace Elements; Uroporphyrinogen Decarboxylase | 1988 |
Porphyrias: inborn errors in heme production.
Topics: Female; Heme; Humans; Liver Diseases; Male; Porphyria, Acute Intermittent; Porphyrias; Skin Diseases; Uroporphyrinogen Decarboxylase | 1988 |
Pathogenesis of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Nervous System; Porphobilinogen; Porphyrias | 1987 |
Porphyria--the UCT experience.
Topics: Acute Disease; Heme; Humans; Porphyrias; South Africa | 1987 |
Mechanisms of chemical-induced porphyrinopathies.
Topics: Heme; Humans; Porphyrias; Porphyrins | 1987 |
Genetic regulation of the heme pathway.
Topics: Animals; Antibodies; Chick Embryo; Erythrocytes; Heme; Humans; Liver Diseases; Porphyrias; Skin Diseases; Uroporphyrinogen Decarboxylase | 1987 |
Hormonal regulation of the heme pathway.
Topics: Animals; Heme; Hormones; Humans; Liver Diseases; Porphyrias | 1987 |
[Porphyria].
Topics: Heme; Humans; Porphyrias | 1987 |
Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases.
Topics: Animals; Bloodletting; Carboxy-Lyases; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Heme; Hexachlorobenzene; Humans; Hydroxamic Acids; Iron; Lead Poisoning; Male; Mice; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases; Uroporphyrinogen Decarboxylase | 1986 |
The porphyrias: recent advances.
Topics: Acute Disease; Adult; Child; Chromatography, High Pressure Liquid; Diagnosis, Differential; Erythrocytes; Heme; Humans; Infant, Newborn; Lead Poisoning; Liver Diseases; Porphobilinogen Synthase; Porphyria, Erythropoietic; Porphyrias; Porphyrias, Hepatic; Porphyrins; Protoporphyria, Erythropoietic; Skin Diseases; Uroporphyrinogen Decarboxylase | 1986 |
Control of 5-aminolevulinate synthase in animals.
Topics: 5-Aminolevulinate Synthetase; Animals; Cytosol; Heme; Humans; Liver; Mitochondria; Mitochondria, Liver; Porphyrias; Reticulocytes | 1986 |
A review of the enzymic errors in the various porphyrias.
Topics: 5-Aminolevulinate Synthetase; Flavoproteins; Heme; Humans; Liver Diseases; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyria, Erythropoietic; Porphyrias; Porphyrias, Hepatic; Porphyrins; Protoporphyria, Erythropoietic; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase | 1985 |
The pigmentation of dental tissues in erythropoietic (congenital) porphyria.
Topics: Adolescent; Adult; Age Factors; Animals; Cattle; Cattle Diseases; Chromatography, Paper; Chromatography, Thin Layer; Dental Enamel; Dentin; Erythropoiesis; Female; Heme; Humans; Methods; Microscopy, Fluorescence; Pigmentation Disorders; Porphyrias; Porphyrins; Staining and Labeling; Tooth Discoloration | 1972 |
Intermittent acute porphyria: the enzymatic defect.
Topics: 5-Aminolevulinate Synthetase; Adenosine Triphosphatases; Alanine; Aminolevulinic Acid; Ammonia-Lyases; Dysautonomia, Familial; Heme; Humans; Liver; Porphobilinogen; Porphyrias; Porphyrins | 1974 |
Porphyria.
Topics: Age Factors; Bone Marrow; Feces; Female; Heme; Humans; Iron; Liver; Male; Photosensitivity Disorders; Porphyrias; Porphyrins; Sex Factors; Sunlight | 1972 |
[Porphyria].
Topics: 5-Aminolevulinate Synthetase; Cytochromes; Glucose; Heme; Humans; Liver; Porphyrias; Porphyrins | 1972 |
The control of haemoglobin synthesis.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Enzyme Activation; Erythropoiesis; Erythropoietin; Fetal Hemoglobin; Globins; Glycine; Heme; Hemoglobins; Humans; Hybrid Cells; Iron; Mitochondria; Oxygen Consumption; Porphyrias; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Succinates; Transcription, Genetic | 1972 |
[Hepatic porphyrias].
Topics: Animals; Heme; Humans; Levulinic Acids; Liver; Porphobilinogen; Porphyrias; Porphyrins | 1972 |
The porphyrias: a review.
Topics: 5-Aminolevulinate Synthetase; Alcoholism; Animals; Barbiturates; Bone Marrow Diseases; Erythropoiesis; Estrogens; Heme; Hemoglobins; Humans; Hyponatremia; Iron; Liver Diseases; Liver Neoplasms; Photosensitivity Disorders; Porphyrias; Porphyrins | 1972 |
Vitamin E and metabolic regulation.
Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex Hormones; Adrenal Glands; Anemia; Anemia, Macrocytic; Animals; Cardiomyopathies; Disease Susceptibility; Encephalomalacia; Female; Genetics; Heme; Hemeproteins; Humans; Infertility; Liver Diseases; Macromolecular Substances; Male; Muscular Dystrophy, Animal; Necrosis; Peroxides; Porphobilinogen Synthase; Porphyrias; Porphyrins; Species Specificity; Vitamin E; Vitamin E Deficiency | 1972 |
[Acute intermittent porphyria in differential diagnosis of acute abdominal diseases].
Topics: 5-Aminolevulinate Synthetase; Abdomen, Acute; Acute Disease; Diagnosis, Differential; Female; Heme; Humans; Male; Porphyrias; Recurrence; Remission, Spontaneous | 1974 |
Endocrine-gene interaction in the pathogenesis of acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Androstenedione; Animals; Biotransformation; Carbon Radioisotopes; Chick Embryo; Heme; Humans; Liver; Molecular Biology; Oxidoreductases; Pedigree; Porphyrias; Porphyrins; Steroids; Testosterone | 1974 |
Lead and hemopoiesis. The mechanism and consequences of the erythropathy of occupational lead poisoning.
Topics: Anemia; Bone Marrow Diseases; Cell Membrane; Cell Survival; Child; Edetic Acid; Erythrocytes; Erythrocytes, Abnormal; Erythropoiesis; Hematologic Diseases; Hematopoiesis; Heme; Hemoglobinopathies; Humans; Iron; Lead; Lead Poisoning; Mitochondria; Occupational Diseases; Osmotic Fragility; Penicillamine; Porphyrias; Porphyrins; Reticulocytes | 1972 |
[Current state of knowledge of the pathology of heme synthesis].
Topics: Anemia, Hypochromic; Anemia, Sideroblastic; Hematologic Diseases; Heme; Humans; Porphyrias; Thalassemia | 1968 |
Biochemical and clinical aspects of the porphyrias.
Topics: Erythropoiesis; Heme; Humans; Liver Diseases; Models, Biological; Photosensitivity Disorders; Porphyrias; Porphyrins | 1968 |
[Porphyrin--how to read its figures].
Topics: Acyltransferases; Anemia; Erythrocytes; Feces; Heme; Hodgkin Disease; Humans; Hydro-Lyases; Lead Poisoning; Leukemia; Levulinic Acids; Porphyrias; Porphyrins; Succinates; Transferases | 1971 |
Recent advances in porphyrin metabolism.
Topics: 5-Aminolevulinate Synthetase; Glucose; Heme; Humans; Liver; Porphyrias; Porphyrins; Vasopressins | 1971 |
3 trial(s) available for heme and Porphyrias
| Article | Year |
|---|---|
Haem-arginate plus tin-protoporphyrin for acute hepatic porphyria.
Topics: Adult; Arginine; Female; Heme; Humans; Liver Diseases; Metalloporphyrins; Porphyrias; Prospective Studies; Protoporphyrins | 1991 |
Controlled trial of haem arginate in acute hepatic porphyria.
Topics: Acute Disease; Adolescent; Arginine; Clinical Trials as Topic; Double-Blind Method; Female; Heme; Heroin; Humans; Infusions, Intravenous; Injections, Intravenous; Liver Diseases; Male; Meperidine; Pain; Phlebitis; Porphyrias; Random Allocation; Recurrence; Severity of Illness Index | 1989 |
Effects of sodium valproate on haem biosynthesis in man: implications for seizure management in the porphyric patient.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Drug Administration Schedule; Epilepsy; Female; Heme; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Valproic Acid | 1988 |
330 other study(ies) available for heme and Porphyrias
| Article | Year |
|---|---|
[Anesthesia in patients with acute porphyria].
Topics: Anesthesia; Heme; Humans; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic | 2022 |
RNA interference therapy in acute hepatic porphyrias.
Topics: Aminolevulinic Acid; Heme; Humans; Pain; Porphyrias; Porphyrias, Hepatic; Quality of Life; RNA Interference | 2023 |
[Biosynthesis of heme and the porphyrias].
Topics: Heme; Humans; Porphyrias | 2023 |
Introduction.
Topics: Biosynthetic Pathways; Heme; Humans; Porphyrias | 2019 |
Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET.
Topics: 1,4-alpha-Glucan Branching Enzyme; Active Transport, Cell Nucleus; Animals; Down-Regulation; Drosophila; Drosophila Proteins; Ecdysteroids; Endocrine Glands; Gene Expression Regulation; Gene Knock-In Techniques; Gene Knockout Techniques; Heme; Iron; Iron Regulatory Protein 1; Iron-Sulfur Proteins; Larva; Mitochondrial Proteins; Porphyrias; RNA, Messenger | 2019 |
Characterization and origin of heme precursors in amniotic fluid: lessons from normal and pathological pregnancies.
Topics: Adult; Amniocentesis; Amniotic Fluid; Cell Differentiation; Coproporphyrins; Female; Heme; Humans; Ileus; Intestinal Atresia; Karyotyping; Maternal Age; Mitochondria; Oxidative Stress; Oxygen; Placenta; Porphyrias; Pregnancy; Prenatal Diagnosis; Protoporphyrins; Retrospective Studies; Uroporphyrins | 2018 |
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Heme; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Oxygen; Photosensitivity Disorders; Photosensitizing Agents; Porphyrias; Porphyrins; Protein Aggregates; Protein Conformation; Protoporphyrins | 2019 |
Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Blastocyst; Cell Differentiation; Cell Line, Tumor; Female; Gene Expression Regulation; Genotype; HEK293 Cells; Heme; Humans; Iron; Iron Regulatory Protein 1; Iron-Sulfur Proteins; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Porphyrias; Protein Biosynthesis; Protoporphyrins; Zebrafish | 2014 |
[Porphyrias : Metabolic disorders of heme biosynthesis].
Topics: Dermatology; Germany; Heme; Humans; Porphyrias; Skin Diseases | 2016 |
[Hereditary porphyrias and heme related disorders].
Topics: Acute Disease; Heme; Heme Oxygenase (Decyclizing); Humans; Porphyrias | 2014 |
The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6.
Topics: Alleles; Animals; ATP-Binding Cassette Transporters; Biological Transport; Cell Membrane; Cohort Studies; Disease Models, Animal; Exome Sequencing; Female; Heme; Humans; Isoantigens; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Porphyrias; Porphyrins; Sequence Homology, Amino Acid; Severity of Illness Index | 2016 |
Case records of the Massachusetts General Hospital. Case 20-2008. A 57-year-old woman with abdominal pain and weakness after gastric bypass surgery.
Topics: Abdominal Pain; Acute Disease; Brain; Cholecystectomy; Diagnosis, Differential; Female; Gastric Bypass; Guillain-Barre Syndrome; Heme; Humans; Magnetic Resonance Imaging; Middle Aged; Porphyria, Variegate; Porphyrias; Porphyrins; Postoperative Complications; Quadriplegia; Sural Nerve; Urine | 2008 |
Multiplex ligation-dependent probe amplification: a novel approach for genetic diagnosis of Porphyria.
Topics: DNA Probes; Heme; Humans; Hydroxymethylbilane Synthase; Nucleic Acid Amplification Techniques; Porphyrias | 2009 |
The porphyrias: clinic, diagnostics, novel investigative tools and evolving molecular therapeutic strategies.
Topics: Animals; Disease Models, Animal; Enzyme Replacement Therapy; Genetic Therapy; Heme; Humans; Porphyrias; Skin Diseases, Genetic | 2010 |
[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment].
Topics: Acute Disease; Adolescent; Arginine; Electromyography; Famotidine; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Nifedipine; Peripheral Nervous System Diseases; Phenobarbital; Porphyrias; Porphyrinogens; Time Factors | 2009 |
Direct assay of delta-aminolevulinic acid dehydratase in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry.
Topics: Aminolevulinic Acid; Deuterium; Erythrocytes; Heme; Humans; Kinetics; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
The porphyrias: pathophysiology.
Topics: Coproporphyrinogen Oxidase; Ferrochelatase; Gene Expression Regulation, Enzymologic; Heme; Humans; Hydroxymethylbilane Synthase; Porphobilinogen Synthase; Porphyrias; Protoporphyrinogen Oxidase; Uroporphyrinogen Decarboxylase; Uroporphyrinogen III Synthetase | 2010 |
Porphyrogenic effect of pentabromodiphenyl ether after repeated administration to rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Dose-Response Relationship, Drug; Female; Flame Retardants; Halogenated Diphenyl Ethers; Heme; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar; Time Factors | 2011 |
Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Gene Expression Regulation, Developmental; Heme; Humans; Liver; Mitochondria, Liver; Mitochondrial Proteins; Peptide Hydrolases; Porphyrias; Protein Transport; RNA Stability; Transcription, Genetic | 2011 |
Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Glucose; Griseofulvin; Heme; Locomotion; Male; Mice; Mice, Inbred ICR; Porphyrias | 2012 |
Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR).
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Binding Sites; Cell Line; Cell Survival; Cells, Cultured; Gene Expression Regulation; Heme; Hepatocytes; Humans; Hydrocarbons; Mice; Mice, Transgenic; Mitochondria; Models, Biological; Polycyclic Aromatic Hydrocarbons; Porphyrias; Promoter Regions, Genetic; Protein Binding; Protoporphyrins; Receptors, Aryl Hydrocarbon; Transcriptional Activation; Xenobiotics | 2012 |
Octabromodiphenyl ether - porphyrogenicity after repeated administration to rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Female; Flame Retardants; Halogenated Diphenyl Ethers; Heme; Liver; Porphyrias; Porphyrins; Rats; Rats, Wistar; Time Factors | 2012 |
[The laboratory diagnostics of disorders of porphyrin metabolism: a lecture].
Topics: Aminolevulinic Acid; Heme; Humans; Porphyrias; Porphyrins | 2012 |
A molecular, enzymatic and clinical study in a family with hereditary coproporphyria.
Topics: Adult; Aminolevulinic Acid; Arginine; Coproporphyrinogen Oxidase; DNA Mutational Analysis; Feces; Female; Heme; Humans; Porphyrias; Protein Denaturation | 2002 |
Lead, chemical porphyria, and heme as a biological mediator.
Topics: Animals; Heme; Humans; Lead Poisoning; Porphyrias | 2002 |
Molecular characterization of porphyrias in Italy: a diagnostic flow-chart.
Topics: DNA; Ferrochelatase; Flavoproteins; Heme; Humans; Hydroxymethylbilane Synthase; Italy; Mitochondrial Proteins; Mutation; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyria, Hepatoerythropoietic; Porphyrias; Porphyrias, Hepatic; Porphyrins; Protoporphyrinogen Oxidase; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sensitivity and Specificity; Spectrometry, Fluorescence; Uroporphyrinogen Decarboxylase | 2002 |
[Clinical manifestations of porphyrin metabolism disorders].
Topics: Acute Disease; Adolescent; Adult; Arginine; Chronic Disease; Female; Heme; Humans; Inosine Diphosphate; Middle Aged; Octreotide; Plasmapheresis; Porphyria, Acute Intermittent; Porphyria, Erythropoietic; Porphyrias; Porphyrins | 2003 |
[The significance of porphyria as disorder of heme synthesis].
Topics: Biochemical Phenomena; Heme; Porphyrias; Porphyrins | 1954 |
Experimental porphyria. IV. Studies of liver catalase and other heme enzymes in sedormid porphyria.
Topics: Catalase; Heme; Humans; Hypnotics and Sedatives; Liver; Porphyrias; Urea | 1955 |
[Urine porphyrin test in liver, duodenal juice and feces as well as its importance in diagnosis of porphyrias and evaluation of disorders of heme synthesis].
Topics: Feces; Gastric Juice; Heme; Hemoglobins; Liver; Porphyrias; Porphyrins | 1956 |
Heme and fatty acid biosynthesis in experimental porphyria.
Topics: Fatty Acids; Heme; Lipid Metabolism; Porphyrias | 1961 |
[New results of research on porphyrin metabolism].
Topics: Anemia; Anemia, Hypochromic; Heme; Humans; Hydrolases; Lead Poisoning; Levulinic Acids; Porphyrias; Porphyrins | 1963 |
CONGENITAL ERYTHROPOIETIC PROTOPORPHYRIA. II. AN EXPERIMENTAL STUDY.
Topics: Animals; Birds; Bone Marrow Examination; Chromatography; Erythropoiesis; Fluorescence; Heme; Metabolism; Porphyrias; Porphyrins; Protoporphyria, Erythropoietic; Research; Spectrophotometry | 1963 |
HEPATOXIC DRUGS CAUSING PORPHYRIA IN MAN AND ANIMALS.
Topics: Animals; Barbiturates; Chemical and Drug Induced Liver Injury; Chick Embryo; Epidemiology; Griseofulvin; Heme; Hepatitis; Hypnotics and Sedatives; Metabolism; Mice; Porphyrias; Porphyrins; Poultry; Pyridines; Rabbits; Rats; Research; Seasons; Toxicology; Turkey; Turkeys | 1963 |
THE METABOLISM OF GLYCINE-2-C14 IN HUMAN PORPHYRIA.
Topics: Benzoates; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Glycine; Heme; Hippurates; Humans; Metabolism; Porphyrias; Proteins; Uric Acid | 1963 |
EPIDERMAL HAEMATIN ENZYMES AND THE METABOLISM OF PORPHYRIC EPIDERMIS.
Topics: Catalase; Cytochromes; Electron Transport Complex IV; Epidermis; Heme; Hemin; Histocytochemistry; Metabolism; Pigmentation; Porphyrias; Skin | 1963 |
[ANEMIAS CAUSED BY ENZYME DEFECTS].
Topics: Adolescent; Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Congenital Nonspherocytic; Anemia, Hypochromic; Carbohydrate Metabolism; Elliptocytosis, Hereditary; Enzymes; Erythrocytes; Favism; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Heme; Humans; Metabolic Diseases; Methemoglobinemia; Pentosephosphates; Porphyrias; Spherocytosis, Hereditary; Thalassemia | 1964 |
THE PORPHYRIAS: DIAGNOSIS BY MEANS OF SIMPLE LABORATORY METHODS.
Topics: Body Fluids; Classification; Clinical Laboratory Techniques; Feces; Heme; Humans; Laboratories; Metabolism; Porphyrias; Porphyrins; Urine | 1964 |
HEMOGLOBIN SYNTHESIS.
Topics: Anemia; Heme; Hemoglobins; Humans; Lead Poisoning; Metabolic Diseases; Porphyrias; Proteins; Vitamin B 6 Deficiency | 1964 |
[NEW DATA ON THE PHYSIOPATHOGENESIS OF ACUTE PORPHYRIA].
Topics: Biochemical Phenomena; Biochemistry; Classification; Heme; Humans; Isomerases; Pathology; Physiology; Porphyria, Acute Intermittent; Porphyrias; Porphyrins | 1964 |
Effect of inosine on heme synthesis in experimental porphyria.
Topics: Heme; Inosine; Nucleosides; Nucleotides; Porphyrias | 1961 |
Volatile anaesthetics induce biochemical alterations in the heme pathway in a B-lymphocyte cell line established from hepatoerythropoietic porphyria patients (LBHEP) and in mice inoculated with LBHEP cells.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Anesthetics; Anesthetics, Inhalation; Animals; B-Lymphocytes; Enflurane; Heme; Humans; Isoflurane; Lymphocytes; Methyl Ethers; Mice; Mice, Inbred BALB C; Mutation; Oxidative Stress; Porphyrias; Sevoflurane; Time Factors | 2004 |
Haems and prophyrins in health and disease.
Topics: Health; Heme; Hemoglobins; Humans; Porphyrias; Porphyrins | 1952 |
Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death.
Topics: Animals; Apoptosis; Caspases; Cell Survival; Collagen Type XI; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heme; Heptanoates; MAP Kinase Signaling System; Membrane Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Neurons; PC12 Cells; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Porphyrias; Rats; RNA-Binding Proteins; RNA, Messenger; SMN Complex Proteins; Up-Regulation; Vesicular Transport Proteins | 2005 |
PGC-1alpha: looking behind the sweet treat for porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Enzyme Activation; Fasting; Glucose; Heat-Shock Proteins; Heme; Humans; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Porphyrias; Transcription Factors; Transcriptional Activation | 2005 |
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha.
Topics: 5-Aminolevulinate Synthetase; Animals; Fasting; Forkhead Box Protein O1; Forkhead Transcription Factors; Genetic Vectors; Glucagon; Glucose; Heme; Insulin; Liver; Male; Mice; Mice, Knockout; Mice, Transgenic; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Porphyrias; Rats; Rats, Wistar; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured; Up-Regulation | 2005 |
Fast track to the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Carbohydrates; Fasting; Heme; Humans; Liver; Porphyrias; Porphyrins | 2005 |
Neurovisceral porphyrias: what a hematologist needs to know.
Topics: Coproporphyria, Hereditary; Erythrocytes; Heme; Humans; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias | 2005 |
[Laboratory tests and therapeutic strategies for the porphyrias].
Topics: Algorithms; Arginine; Critical Care; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Genetic Predisposition to Disease; Heme; Humans; Photosensitivity Disorders; Porphyria Cutanea Tarda; Porphyrias | 2006 |
Direct assay of enzymes in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Uroporphyrinogen decarboxylase and coproporphyrinogen III oxidase.
Topics: Aerobiosis; Coproporphyrinogen Oxidase; Heme; Humans; Molecular Structure; Porphyrias; Substrate Specificity; Tandem Mass Spectrometry; Uroporphyrinogen Decarboxylase | 2008 |
Direct assay of enzymes in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Porphobilinogen deaminase.
Topics: Enzyme Stability; Erythrocytes; Heme; Hot Temperature; Humans; Hydroxymethylbilane Synthase; Molecular Structure; Porphyrias; Tandem Mass Spectrometry | 2008 |
Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol.
Topics: 5-Aminolevulinate Synthetase; Alcohol Drinking; Animals; Ethanol; Gene Expression; Heme; Heme Oxygenase-1; Liver; Male; Porphyrias; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
Carbon monoxide production associated with ineffective erythropoiesis.
Topics: Adolescent; Adult; Aged; Anemia; Anemia, Sideroblastic; Bile Pigments; Bilirubin; Carbon Isotopes; Carbon Monoxide; Chromium Isotopes; Erythropoiesis; Feces; Female; Glycine; Heme; Hemoglobinometry; Humans; Iron; Iron Isotopes; Leukopenia; Male; Middle Aged; Porphyrias; Thalassemia | 1967 |
Steroid induction of porphyrin synthesis in liver cell culture.
Topics: Culture Techniques; Etiocholanolone; Glucocorticoids; Heme; Humans; Liver; Porphyrias; Porphyrins | 1967 |
Carbamazepine-induced non-hereditary acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Carbamazepine; Diagnosis, Differential; Epilepsy; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphyrias | 1983 |
Metabolism as a prerequisite for the porphyrinogenic action of polyhalogenated aromatics, with special reference to hexachlorobenzene and polybrominated biphenyls (Firemaster BP-6).
Topics: 5-Aminolevulinate Synthetase; Animals; Biotransformation; Biphenyl Compounds; Cells, Cultured; Chick Embryo; Chlorobenzenes; Enzyme Induction; Heme; Hexachlorobenzene; Liver; Polybrominated Biphenyls; Porphyrias; Porphyrins; Spectrometry, Fluorescence | 1980 |
Heme utilization by rat liver tryptophan pyrrolase as a screening test for exacerbation of hepatic porphyrias by drugs.
Topics: Animals; Ditiocarb; Heme; Liver; Liver Diseases; Male; Porphyrias; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1981 |
[The porphyria cutanea tarda group: their role among the enzyme defects of heme biosynthesis].
Topics: Carboxy-Lyases; Erythropoiesis; Heme; Humans; Iron; Liver Diseases; Porphyrias; Skin Diseases; Uroporphyrinogen Decarboxylase | 1984 |
The biochemical basis of the acute porphyrias.
Topics: Acute Disease; Aminolevulinic Acid; Heme; Humans; Nervous System Diseases; Porphyrias; Porphyrins | 1983 |
Vampires: when fantasy meets reality.
Topics: Female; Heme; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Literature, Modern; Male; Mythology; Porphyrias | 1983 |
Modified uroporphyrinogen decarboxylase activity in a yeast mutant which mimics porphyria cutanea tarda.
Topics: Animals; Carboxy-Lyases; Heme; Mutation; Porphyrias; Saccharomyces cerevisiae; Skin Diseases; Spectrophotometry; Uroporphyrinogen Decarboxylase | 1984 |
Protoporphyrinogen oxidase and ferrochelatase in porphyria variegata.
Topics: Adult; Ascorbic Acid; Chlorides; Female; Ferric Compounds; Ferrochelatase; Ferrous Compounds; Flavoproteins; Glutathione; Heme; Humans; Leukocytes; Lyases; Male; Middle Aged; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphyrias; Protoporphyrinogen Oxidase; Protoporphyrins | 1983 |
Drugs and porphyria.
Topics: Acute Disease; Drug-Related Side Effects and Adverse Reactions; Heme; Humans; Porphyrias | 1984 |
Hematin-induced hemolysis in acute porphyria.
Topics: Adult; Anemia, Hemolytic; Female; Heme; Hemin; Humans; Porphyrias | 1984 |
Abnormalities in liver function and morphology and impaired aminopyrine metabolism in hereditary hepatic porphyrias.
Topics: Adult; Aminopyrine; Bile Acids and Salts; Biopsy; Breath Tests; Female; Heme; Humans; Liver; Liver Diseases; Male; Microscopy, Electron; Middle Aged; Porphyrias | 1983 |
L-tryptophan: a common denominator of biochemical and neurological events of acute hepatic porphyria?
Topics: Animals; Brain; Heme; Liver; Liver Diseases; Male; Nervous System Diseases; Porphyrias; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase | 1983 |
Orphan biologic licensed.
Topics: Heme; Hemin; Humans; Licensure; Porphyrias; United States | 1983 |
[Acute intermittent porphyria].
Topics: Acute Disease; Chlorpromazine; Diarrhea; Heme; Hemin; Humans; Intestinal Obstruction; Mitochondria, Liver; Pain; Porphyrias; Porphyrins; Propranolol | 1983 |
Effect of heme on allylisopropylacetamide-induced changes in heme and drug metabolism in the rhesus monkey (Macaca mulatta).
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Enzyme Activation; Ethylmorphine-N-Demethylase; Female; Heme; Heme Oxygenase (Decyclizing); Macaca mulatta; Microsomes, Liver; Porphyrias; Porphyrins | 1983 |
Hemin infusions in acute intermittent porphyria.
Topics: Acute Disease; Heme; Hemin; Humans; Infusions, Parenteral; Porphyrias; Recurrence | 1984 |
Effect of prolonged fasting on heme metabolism in the rat.
Topics: 5-Aminolevulinate Synthetase; Animals; Chromatography, Thin Layer; Fasting; Heme; Male; Phenobarbital; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains | 1984 |
Abnormal haem biosynthesis in chronic alcoholics.
Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Alcoholism; Anemia, Sideroblastic; Coproporphyrinogen Oxidase; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Liver Diseases; Male; Middle Aged; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase | 1981 |
Effects of haem infusion on biliary secretion of porphyrins, haem and bilirubin in man.
Topics: Adult; Aged; Bile; Bilirubin; Coproporphyrins; Female; Heme; Humans; Injections; Male; Middle Aged; Porphyrias; Porphyrins; Protoporphyrins; Skin Diseases | 1982 |
Alterations in the heme biosynthetic pathway as an index of exposure to toxins.
Topics: Cytochrome P-450 Enzyme System; Environmental Pollutants; Heme; Hexachlorobenzene; Hydrocarbons, Chlorinated; Lead; Polychlorinated Biphenyls; Porphyrias; Porphyrins | 1982 |
Hematin: unique effects of hemostasis.
Topics: Adult; Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Fibrinogen; Glucose; Heme; Hemin; Heparin; Humans; In Vitro Techniques; Male; Platelet Aggregation; Porphyrias | 1983 |
Acute variegate porphyria following a Scarsdale Gourmet Diet.
Topics: Adult; Coma; Diet, Reducing; Female; Heme; Hemin; Humans; Infusions, Parenteral; Porphyrias | 1983 |
Pathogenesis and treatment of acute intermittent porphyria: discussion paper.
Topics: Acute Disease; Aminolevulinic Acid; Blood-Brain Barrier; Heme; Humans; Liver Diseases; Porphobilinogen; Porphyrias | 1983 |
Environmental and drug factors in hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Allyl Compounds; Aminolevulinic Acid; Barbiturates; Chemical and Drug Induced Liver Injury; Dicarbethoxydihydrocollidine; Drug-Related Side Effects and Adverse Reactions; Environmental Exposure; Enzyme Activation; Estrogens; Ethanol; Griseofulvin; Heme; Humans; Hydrocarbons, Chlorinated; Iron; Liver; Porphyrias; Porphyrinogens | 1982 |
The porphyrias: clinical chemistry, diagnosis and methodology.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clinical Laboratory Techniques; Feces; Female; Heme; Humans; Hydroxymethylbilane Synthase; Male; Methods; Porphyrias; Porphyrinogens; Porphyrins; Skin Diseases; Tissue Distribution | 1980 |
Alterations in haem biosynthesis during the human menstrual cycle: studies in normal subjects and patients with latent and active acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases; Male; Menstruation; Middle Aged; Porphobilinogen; Porphyrias | 1982 |
[Cutaneous porphyrias (author's transl)].
Topics: Heme; Humans; Liver Diseases; Photosensitivity Disorders; Porphyrias; Porphyrins; Skin Diseases | 1982 |
[Intravenous hematin treatment of acute intermittent porphhyria].
Topics: Acute Disease; Aged; Heme; Hemin; Humans; Injections, Intravenous; Male; Porphyrias | 1982 |
[Porphyria].
Topics: Heme; Humans; Porphyrias; Porphyrins | 1982 |
Screening for latent acute intermittent porphyria: the value of measuring both leucocyte delta-aminolaevulinic acid synthase and erythrocyte uroporphyrinogen-1-synthase activities.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aged; Ammonia-Lyases; Child; Clinical Enzyme Tests; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Middle Aged; Porphyrias; Reference Values | 1982 |
Neurotoxic aspects of porphyrinopathies: lead and succinylacetone.
Topics: 5-Aminolevulinate Synthetase; Animals; Brain; gamma-Aminobutyric Acid; Heme; Heptanoates; Heptanoic Acids; Lead; Porphyrias; Rats; Seizures | 1982 |
[Hemin treatment in a case of porphyria variegata].
Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Female; Heme; Hemin; Humans; Liver Diseases; Porphobilinogen; Porphyrias; Uroporphyrins | 1982 |
[Porphyrinogenic effect of carbon disulfide during occupational exposure].
Topics: Adult; Air Pollutants; Air Pollutants, Occupational; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Heme; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Porphyrins | 1982 |
Effect of Griseofulvin on 5-aminolevulinate synthase and on ferrochelatase in mouse liver neoplastic nodules.
Topics: 5-Aminolevulinate Synthetase; Animals; Diet; Ferrochelatase; Griseofulvin; Heme; Hemin; Liver; Liver Neoplasms; Lyases; Male; Mice; Neoplasms, Experimental; Porphyrias; Protoporphyrins | 1981 |
Treatment of porphyria.
Topics: Heme; Hemin; Humans; Porphyrias | 1981 |
Enzyme defects in the porphyrias and their relevance to the biochemical abnormalities in these disorders.
Topics: Fibroblasts; Heme; Humans; Liver; Porphyrias | 1981 |
Treatment of the porphyrias: mechanisms of action.
Topics: 5-Aminolevulinate Synthetase; Heme; Hemin; Humans; Liver; Porphyrias; Skin Diseases | 1981 |
Effects of porphyrinogenic (porphyria-producing) agents on avian embryonic hepatic glutathione S-transferase activity.
Topics: Acetamides; Allylisopropylacetamide; Animals; Chick Embryo; Cyproterone; Cytochrome P-450 Enzyme System; Cytosol; Glutathione Transferase; Heme; Liver; Phenobarbital; Porphyrias | 1981 |
Treatment with haematin in acute hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Female; Heme; Hemin; Humans; Leukocytes; Liver Diseases; Male; Middle Aged; Porphyrias; Porphyrins | 1981 |
Coagulopathy associated with hematin treatment for acute intermittent porphyria.
Topics: Acute Disease; Adult; Blood Coagulation Disorders; Female; Heme; Hemin; Humans; Porphyrias; Recurrence | 1981 |
[Recent clinicopathological findings on porphyrin-heme metabolism].
Topics: Adult; Heme; Humans; Porphyrias; Porphyrins; Skin Diseases | 1981 |
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts.
Topics: Adult; Biopsy; Coproporphyrins; Feces; Female; Ferrochelatase; Fibroblasts; Heme; Humans; Oxidation-Reduction; Oxidoreductases; Porphobilinogen; Porphyrias; Porphyrinogens; Protoporphyrins; Skin; Uroporphyrins | 1980 |
Hepatoerythropoietic porphyria.
Topics: Adolescent; Adult; Anemia; Bone Marrow Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Genes, Dominant; Genes, Recessive; Heme; Humans; Liver Diseases; Male; Middle Aged; Photosensitivity Disorders; Porphyrias; Prognosis; Skin Diseases | 1980 |
Hepatic protoporphyrin production in human protoporphyria. Effects of intravenous hematin and analysis of erythrocyte protoporphyrin distribution.
Topics: Adult; Erythrocytes; Feces; Female; Heme; Hemin; Humans; Injections, Intravenous; Liver; Male; Models, Biological; Porphyrias; Porphyrins; Protoporphyrins | 1980 |
Congenital porphyria.
Topics: Adolescent; Blood; Bone Marrow; Child; Child, Preschool; Diagnosis, Differential; Erythropoiesis; Female; Genes, Recessive; Heme; Humans; Liver; Male; Pedigree; Porphyria, Acute Intermittent; Porphyrias; Skin; Spleen | 1980 |
Drugs and the hepatic porphyrias.
Topics: Acetamides; Aminolevulinic Acid; Animals; Barbiturates; Cats; Dicarbethoxydihydrocollidine; Dogs; Griseofulvin; Heme; Humans; Hydrocarbons, Halogenated; Hypnotics and Sedatives; Iron; Liver; Liver Diseases; Porphyrias | 1980 |
The activities of the enzymes of haem biosynthesis in the porphyrias and during treatment of acute intermittent porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Ammonia-Lyases; Erythrocytes; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Porphyrias; Porphyrins; Skin Diseases | 1980 |
Hematin therapy in porphyric attacks.
Topics: Heme; Hemin; Humans; Porphyrias | 1980 |
Haem control in experimental porphyria. The effect of haemin on the induction of delta-aminolaevulinate synthase in isolated chick-embryo liver cells.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Enzyme Induction; Heme; Hemin; In Vitro Techniques; Liver; Porphyrias | 1980 |
Evidence that in chick embryos destruction of hepatic microsomal cytochrome P-450 haem is a general mechanism of induction of delta-aminolaevulinate synthase by porphyria-causing drugs.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Microsomes, Liver; Phenobarbital; Porphyrias; Proadifen | 1980 |
New treatment for porphyria to be studied.
Topics: Arginine; Female; Heme; Humans; Infusions, Intravenous; Male; Porphyrias | 1995 |
Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Enzyme Repression; Ferric Compounds; Glutethimide; Heme; Heme Oxygenase (Decyclizing); Heptanoates; Kinetics; Liver; Metalloporphyrins; Nitrilotriacetic Acid; Porphyrias | 1994 |
The influence of porphyrogenic drugs on the glyoxalase enzymes.
Topics: Allylisopropylacetamide; Barbiturates; Chloramphenicol; Diazepam; Erythrocytes; Heme; Hemoglobins; Humans; Kinetics; Lactoylglutathione Lyase; Oxytetracycline; Porphyrias; Protoporphyrins; Spectrophotometry, Ultraviolet; Sulfamethazine; Thiolester Hydrolases | 1993 |
Advances in understanding and treating 'the little imitator,' acute porphyria.
Topics: Acute Disease; Heme; Heme Oxygenase (Decyclizing); Humans; Nervous System Diseases; Porphyrias | 1993 |
[Molecular pathology of heme biosynthesis].
Topics: Animals; Gene Expression Regulation, Enzymologic; Heme; Humans; Iron; Mutation; Porphyrias | 1993 |
Proceedings of the Laboratory Medicine '95 11th IFCC European Congress of Clinical Chemistry, Tampere, Finland, 2-7 July 1995 and International Symposium on Porphyrias and Heme-related Disorders: Molecular Basis, Diagnostic, and Clinical Aspects, Helsinki
Topics: Animals; Biomarkers; Chemistry, Clinical; Heme; Humans; Porphyrias | 1995 |
Epilepsy in porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease-Free Survival; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Heme; Humans; Liver; Male; Porphyrias; Porphyrias, Hepatic | 1996 |
Three cases of acute porphyria-experience with heme therapy in one case.
Topics: Acute Disease; Adult; Dietary Carbohydrates; Female; Glucose; Heme; Hemin; Humans; Infusions, Intravenous; Male; Porphyrias; Time Factors | 1995 |
The prooxidant effect of 5-aminolevulinic acid in the brain tissue of rats: implications in neuropsychiatric manifestations in porphyrias.
Topics: Aminolevulinic Acid; Animals; Biological Transport; Brain; Calcium; Catalase; Cerebral Cortex; Ferritins; Glutathione Peroxidase; Heme; Kinetics; Male; Nerve Tissue Proteins; Oxidants; Porphyrias; Rats; Rats, Wistar; Receptors, Cell Surface; Sulfhydryl Compounds; Synaptic Membranes; Synaptosomes | 1996 |
The maddening business of King George III and porphyria.
Topics: Ammonia-Lyases; England; Famous Persons; Heme; History, 18th Century; History, 19th Century; Humans; Male; Mental Disorders; Pedigree; Porphyrias | 1996 |
Glucose inhibits phenobarbital-induced delta-aminolevulinate synthase expression in normal but not in diabetic rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 5-Aminolevulinate Synthetase; Adenylyl Cyclases; Animals; Blood Glucose; Bucladesine; Cyclic AMP; Diabetes Mellitus, Experimental; Enzyme Induction; Enzyme Inhibitors; Glucose; Heme; Immunity, Innate; Liver; Male; Phenobarbital; Porphyrias; Rats; Second Messenger Systems; Streptozocin | 1996 |
[Porphyria--a metabolic mine field].
Topics: Counseling; Heme; Humans; Porphyrias; Regional Medical Programs; Social Support; Sweden | 1998 |
The diagnosis of porphyria.
Topics: Aminolevulinic Acid; Female; Genetic Techniques; Genetic Testing; Heme; Humans; Mutation; Porphobilinogen; Porphyrias; Porphyrins | 1999 |
[Clinical manifestations and diagnosis of acute porphyria].
Topics: Acute Disease; Adult; Arginine; Critical Care; Diagnosis, Differential; Female; Glucose; Heme; Humans; Infusions, Intravenous; Male; Middle Aged; Porphyrias; Pregnancy; Quality of Life; Respiration, Artificial | 1999 |
Heme metabolism and lipid peroxidation in rat kidney hexachlorobenzene-induced porphyria: A compartmentalized study of biochemical pathogenic mechanisms.
Topics: Animals; Biomarkers; Enzyme Inhibitors; Female; Heme; Hexachlorobenzene; Kidney; Kidney Cortex; Lipid Peroxidation; Liver; Malondialdehyde; Porphyrias; Porphyrins; Rats; Rats, Wistar; Uroporphyrinogen Decarboxylase | 2000 |
Spontaneous porphyria of the Long-evans cinnamon rat: an animal model of Wilson's disease.
Topics: Aging; Animals; Bone Marrow; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Heme; Hepatolenticular Degeneration; Humans; Kidney; Liver; Male; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats; Rats, Inbred LEC; Sex Characteristics; Spleen | 2000 |
Hepatocellular carcinoma in patients with acute hepatic porphyria: frequency of occurrence and related factors.
Topics: Acute Disease; Adult; Carcinoma, Hepatocellular; Cohort Studies; Female; Heme; Humans; Incidence; Liver Neoplasms; Male; Melatonin; Middle Aged; Porphyrias; Porphyrias, Hepatic; Prospective Studies; Risk Factors; Survival Analysis | 2000 |
Porphyrias: photosensitivity and phototherapy.
Topics: Furocoumarins; Heme; Humans; Photochemotherapy; Photosensitizing Agents; Phototherapy; Porphyrias; Ultraviolet Therapy | 2000 |
Heme metabolism after discontinued hexachlorobenzene administration in rats: possible irreversible changes and biomarker for hexachlorobenzene persistence.
Topics: Adipose Tissue; Animals; Animals, Outbred Strains; Biomarkers; Drug Administration Schedule; Enzyme Inhibitors; Female; Fungicides, Industrial; Heme; Hexachlorobenzene; Liver; Porphyrias; Rats; Rats, Wistar; Time Factors; Uroporphyrinogen Decarboxylase | 2000 |
Drug-induced exacerbations of porphyria.
Topics: Alkylating Agents; Analgesics; Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Central Nervous System Stimulants; Chick Embryo; Disease Models, Animal; Heme; Humans; Hypnotics and Sedatives; Hypoglycemic Agents; Liver; Porphyrias; Psychotropic Drugs; Tranquilizing Agents | 1976 |
The primary enzyme defect in hereditary coproporphyria.
Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Coproporphyrinogens; Coproporphyrins; Feces; Female; Fibroblasts; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Male; Oxidoreductases; Porphyrias; Porphyrias, Hepatic; Skin | 1976 |
Enzyme abnormalities in the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Ammonia-Lyases; Chronic Disease; Clinical Enzyme Tests; Coproporphyrinogen Oxidase; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Models, Biological; Porphobilinogen Synthase; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase | 1977 |
Treatment of acute hepatic porphyria.
Topics: Acute Disease; Heme; Hemin; Humans; Liver; Liver Diseases; Porphyrias | 1978 |
Prevention of acute porphyric attacks by intravenous haematin.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Pressure; Circadian Rhythm; Drug Evaluation; Female; Heme; Hemin; Humans; Infusions, Parenteral; Menstruation; Porphobilinogen; Porphyrias; Pulse; Remission, Spontaneous | 1978 |
Haematin therapy and leucocyte delta-aminolevulinic-acid-synthase activity in prolonged attack of acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Drug Administration Schedule; Female; Heme; Hemin; Humans; Infusions, Parenteral; Leukocytes; Peak Expiratory Flow Rate; Porphyrias; Respiration; Time Factors | 1979 |
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinogen; Porphyrias; Pyrroles | 1979 |
Effect of hematin in porphyric neuropathy.
Topics: Adult; Female; Heme; Hemin; Humans; Peripheral Nervous System Diseases; Porphyrias | 1977 |
Toxicity of PBBs with special reference to porphyrinogenic action and spectral interaction with hepatic cytochrome P-450.
Topics: Alanine Transaminase; Animals; Bile; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Glutamate Dehydrogenase; Heme; Kidney; Liver; Male; Polybrominated Biphenyls; Porphyrias; Porphyrinogens; Porphyrins; Quail | 1978 |
Postulated deficiency of hepatic heme and repair by hematin infusions in the "inducible" hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Adult; Female; Heme; Hemin; Humans; Liver; Male; Porphobilinogen; Porphyrias | 1977 |
Addictions: some reasons for investigating their hematology.
Topics: Alcoholism; Carbohydrates; Heme; Humans; Lead; Porphyrias; Psychotropic Drugs; Substance-Related Disorders | 1978 |
Drug sensitivity in hereditary hepatic porphyria.
Topics: Ammonia-Lyases; Animals; Coproporphyrinogen Oxidase; Erythrocytes; Female; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Lyases; Male; Oxidoreductases; Pharmaceutical Preparations; Porphyrias; Rats | 1978 |
Hematin therapy for acute porphyria.
Topics: Acute Disease; Adult; Animals; Drug Evaluation; Female; Heme; Hemin; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Porphyrias | 1979 |
[Effect of hematin in acute porphyric relapse].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Heme; Hemin; Humans; Male; Porphobilinogen; Porphyrias; Uroporphyrins | 1979 |
Haem biosynthesis in cutaneous hepatic porphyria: comparison with alcoholism and liver disease.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases, Alcoholic; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase | 1979 |
Reduced ferrochelatase activity in fibroblasts from patients with porphyria variegata.
Topics: Fibroblasts; Heme; Humans; Lyases; Porphyrias; Protoporphyria, Erythropoietic | 1979 |
Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase.
Topics: Animals; Dicarbethoxydihydrocollidine; Enzyme Inhibitors; Heme; Liver; Lyases; Male; Mice; Porphyrias; Porphyrins; Pyridines; Rats | 1979 |
Hematin and propranolol in acute intermittent porphyria. Full recovery from quadriplegic coma and respiratory failure.
Topics: Acute Disease; Adolescent; Coma; Heme; Hemin; Humans; Infusions, Parenteral; Male; Porphyrias; Propranolol; Quadriplegia; Respiratory Insufficiency | 1979 |
[Hematin treatment of acute intermittent porphyria. A case report (author's transl)].
Topics: Adolescent; Aminolevulinic Acid; Antihypertensive Agents; Electromyography; Female; Heme; Hemin; Humans; Infusions, Parenteral; Lung; Porphobilinogen; Porphyrias | 1979 |
[Acute intermittent porphyria--a clinical review].
Topics: Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Heme; Humans; Porphobilinogen; Porphyrias | 1979 |
Heme content of normal and porphyric cultured skin fibroblasts.
Topics: Cells, Cultured; Cytochromes; Fibroblasts; Heme; Humans; Porphyrias; Porphyrins; Skin; Spectrum Analysis | 1977 |
Enzyme deficiencies in the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Enzymes; Heme; Humans; Liver; Oxidoreductases; Porphyria, Erythropoietic; Porphyrias; Protoporphyria, Erythropoietic | 1977 |
Haem biosynthesis in peripheral blood in erythropoietic protoporphyria.
Topics: Adult; Aged; Child; Female; Heme; Humans; Male; Middle Aged; Porphyrias; Porphyrins; Protoporphyrins | 1977 |
[Hematin therapy of porphyrin neuropathy].
Topics: Adult; Heme; Hemin; Humans; Neurologic Manifestations; Paralysis; Porphyrias | 1977 |
Deficient induction of uroporphyrinogen-I synthase activity in mitogen-stimulated lymphocytes from patients with acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Ammonia-Lyases; Catalase; Enzyme Induction; Female; Heme; Humans; Hydroxymethylbilane Synthase; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Porphyrias | 1977 |
Transitory renal failure following rapid administration of a relatively large amount of hematin in a patient with acute intermittent porphyria in clinical remission.
Topics: Acute Kidney Injury; Adult; Heme; Hemin; Humans; Infusions, Parenteral; Kidney Tubules; Male; Necrosis; Porphyrias; Remission, Spontaneous | 1978 |
Variegate porphyria.
Topics: Acute Disease; Adult; Child; Feces; Heme; Humans; Porphyrias; Porphyrins; Skin | 1978 |
Tryptophan pyrrolase, the regulatory free haem and hepatic porphyrias. Early depletion of haem by clinical and experimental exacerbators of porphyria.
Topics: Animals; Dicarbethoxydihydrocollidine; Heme; Liver; Liver Diseases; Male; Porphyrias; Rats; Tryptophan Oxygenase | 1978 |
Anesthesia and the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Anesthesia; Barbiturates; Erythropoiesis; Heme; Humans; Liver Diseases; Porphyrias; Porphyrins | 1978 |
Biochemical studies on erythropoietic protoporphyria.
Topics: Erythrocytes; Erythropoietin; Heme; Humans; Light; Porphyrias; Porphyrins; Protoporphyrins | 1978 |
[The basis of porphyria cutanea tarda].
Topics: Female; Heme; Humans; Male; Porphyrias; Porphyrins; Skin Manifestations | 1978 |
The biosynthesis of haem in congenital (erythropoietic) porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Child; Child, Preschool; Coproporphyrinogens; Erythrocytes; Erythropoiesis; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrinogens | 1978 |
Studies in porphyria. VI. Biosynthesis of porphyrins in mammalian skin and in the skin of porphyric patients.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Heme; Humans; Hydroxymethylbilane Synthase; Levulinic Acids; Liver; Male; Mice; Organ Culture Techniques; Porphyrias; Porphyrins; Rats; Skin | 1977 |
Turnover of cytochrome P-450 and cytochrome b5 hemes in griseofulvin-induced murine porphyria.
Topics: Animals; Cytochrome P-450 Enzyme System; Cytochromes; Griseofulvin; Heme; Male; Mice; Microsomes, Liver; Porphyrias; Regression Analysis; Time Factors | 1977 |
Experimental porphyrias as models for human hepatic porphyrias.
Topics: Animals; Disease Models, Animal; Heme; Humans; Iron; Liver Diseases; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1977 |
Hereditary coproporphyria. Demonstration of the abnormalities in haem biosynthesis in peripheral blood.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Child; Coproporphyrinogen Oxidase; Coproporphyrins; Erythrocytes; Feces; Female; Heme; Humans; Leukocytes; Male; Middle Aged; Pedigree; Photosensitivity Disorders; Porphyrias | 1977 |
Pathogenesis of neural manifestations in acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Anura; Brain; Heme; Humans; In Vitro Techniques; Mice; Neurologic Manifestations; Porphobilinogen; Porphyrias; Rats | 1977 |
Reduced ferrochelatase activity: a defect common to porphyria variegata and protoporphyria.
Topics: Adolescent; Adult; Erythroblasts; Erythrocytes; Female; Ferrochelatase; Heme; Humans; In Vitro Techniques; Lyases; Male; Middle Aged; Porphyrias | 1977 |
Plumbism from airborne lead in a firing range. An unusual exposure to a toxic heavy metal.
Topics: Adolescent; Air Pollution; Aminolevulinic Acid; Coproporphyrins; Diagnosis, Differential; Erythrocytes; Heme; Humans; Lead; Lead Poisoning; Liver Diseases; Male; Occupational Diseases; Porphobilinogen Synthase; Porphyrias; Protoporphyrins | 1977 |
Effects of hexachlorobenzene feeding and iron overload on enzymes of haem biosynthesis and cytochrome P 450 in rat liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Siderosis; Time Factors; Uroporphyrinogen Decarboxylase | 1977 |
Alterations in the activity of enzymes of haem biosynthesis in lead poisoning and acute hepatic prophyria.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Child; Coproporphyrinogen Oxidase; Female; Ferrochelatase; Heme; Humans; Lead Poisoning; Male; Middle Aged; Porphobilinogen Synthase; Porphyrias | 1977 |
The treatment of acute intermittent porphyria with laevulose.
Topics: 5-Aminolevulinate Synthetase; Coproporphyrinogen Oxidase; Erythrocytes; Ferrochelatase; Fructose; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase | 1977 |
[Clinical biochemistry: emphasis on porphyria].
Topics: Alcoholism; Biochemical Phenomena; Biochemistry; Coproporphyrins; Erythropoiesis; Female; Heme; Humans; Lead Poisoning; Liver; Liver Diseases; Male; Porphyrias; Porphyrins; Pregnancy | 1977 |
Is porphobilinogen deaminase activity a secondary control mechanism in haem biosynthesis in humans? [proceedings].
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Erythrocytes; Heme; Humans; Hydroxymethylbilane Synthase; Lead Poisoning; Leukocytes; Porphyrias | 1977 |
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Heme; Hemin; Humans; Infusions, Parenteral; Porphobilinogen; Porphyrias; Remission, Spontaneous | 1976 |
The hepatic porphyrias: pathogenesis, manifestations, and management.
Topics: 5-Aminolevulinate Synthetase; Birefringence; Heme; Humans; Liver; Liver Diseases; Neurologic Manifestations; Pigmentation; Porphyrias; Porphyrins | 1976 |
The activities of uroporphyrinogen synthetase and cosynthetase in congenital erythropoietic porphyria (CEP).
Topics: Adult; Ammonia-Lyases; Erythrocyte Aging; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Isomerases; Male; Porphyrias; Porphyrins; Reticulocytes; Uroporphyrinogen III Synthetase | 1976 |
Hepatic haem metabolism in porphyria cutanea tarda (PCT): enzymatic studies and their relation to liver ultrastructure.
Topics: Aminopyrine; Animals; Benzopyrenes; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Hexachlorobenzene; Humans; Hydroxylation; Iron; Liver; Microscopy, Electron; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats | 1976 |
The hepatic lesion in protoporphyria (PP): preliminary studies of haem metabolism, liver structure and ultrastructure.
Topics: Adult; Cytochrome P-450 Enzyme System; Heme; Humans; Liver; Microscopy, Electron; Microscopy, Fluorescence; Microscopy, Polarization; Porphyrias; Porphyrins; Protoporphyrins | 1976 |
Hepta- and hexa-carboxylic porphyrinogen intermediates in haem biosynthesis.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Coproporphyrinogens; Decarboxylation; Erythrocytes; Heme; Humans; Porphyrias; Porphyrinogens; Protoporphyrins | 1976 |
The effect of environmental light exposure on drug-induced porphyria in the rat.
Topics: Animals; Dicarbethoxydihydrocollidine; Disease Models, Animal; Heme; Light; Male; Porphyrias; Porphyrins; Rats; Skin | 1976 |
Porphyria in relation to surgery and anaesthesia.
Topics: 5-Aminolevulinate Synthetase; Adult; Anesthesia; Barbiturates; Chlorpromazine; Contraceptives, Oral; Female; Heme; Hexamethonium Compounds; Humans; Liver; Male; Menstruation; Porphyrias; Porphyrins; Pregnancy; Structure-Activity Relationship | 1975 |
Effects of hematin in hepatic porphyria. Further studies.
Topics: Adult; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Recurrence | 1975 |
Editorial: Hematin and porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Animals; Female; Heme; Hemin; Humans; Kidney Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Rabbits; Rats | 1975 |
Anesthesia and the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Anesthesia; Anesthetics; Child; Chlordiazepoxide; Cytochrome P-450 Enzyme System; Demyelinating Diseases; Diazepam; Heme; Humans; Neostigmine; Pentazocine; Porphobilinogen; Porphyrias; Thiopental | 1975 |
[The etiopathogenesis and clinical classification of congenital and acquired porphyrias].
Topics: Animals; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrinogens; Porphyrins | 1975 |
Heme synthetase deficiency in human protoporphyria. Demonstration of the defect in liver and cultured skin fibroblasts.
Topics: 5-Aminolevulinate Synthetase; Animals; Fibroblasts; Genes; Heme; Humans; In Vitro Techniques; Iron; Liver; Lyases; Mitochondria, Liver; Mutation; Porphyrias; Protoporphyrins; Rats | 1975 |
Regulation of rat liver tryptophan pyrrolase by its cofactor haem: Experiments with haematin and 5-aminolaevulinate and comparison with the substrate and hormonal mechanisms.
Topics: Aminolevulinic Acid; Apoenzymes; Cycloheximide; Dactinomycin; Hematinics; Heme; Hydrocortisone; Liver; Porphyrias; Porphyrinogens; Puromycin; Tryptophan; Tryptophan Oxygenase | 1975 |
Erythropoietic protoporphyria. 10 years experience.
Topics: Adolescent; Adult; Carotenoids; Child; Child, Preschool; Cholelithiasis; Erythrocytes; Erythropoiesis; Female; Follow-Up Studies; Genes, Dominant; Heme; Humans; Liver Diseases; Male; Middle Aged; Phenotype; Photosensitivity Disorders; Porphyrias; Porphyrins; Protoporphyrins; Skin; Sunlight | 1976 |
Rapid normalization of antipyrine oxidation by heme in variegate porphyria.
Topics: Adult; Aged; Antipyrine; Female; Glucaric Acid; Half-Life; Heme; Humans; Hydrocortisone; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Porphyrias | 1992 |
Effects of acute carbamazepine administration on haem metabolism in rat liver.
Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Male; Porphyrias; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1992 |
[Evaluation of the effects of reduced glutathione in subjects with acquired and congenital changes in heme biosynthesis].
Topics: Aminolevulinic Acid; Coproporphyrins; Glutathione; Heme; Humans; Lead Poisoning; Porphyrias; Porphyrins; Skin Diseases; Time Factors; Uroporphyrins | 1992 |
[46-year-old patient with congenital actinic dermatosis and progressive liver failure after travel to Southeast Asia].
Topics: Bilirubin; Heme; Hepatic Encephalopathy; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Photosensitivity Disorders; Porphyrias; Protoporphyrins; Travel | 1991 |
Sex comparison of heme pathway in rats bearing hepatic tumors.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hydroxymethylbilane Synthase; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Sex Characteristics | 1991 |
Regulation of cadmium induced porphyria by ascorbic acid in chick embryos.
Topics: Animals; Ascorbic Acid; Cadmium; Chick Embryo; Dithiothreitol; Heme; Porphyrias | 1991 |
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Mechanism of drug action.
Topics: Animals; Binding Sites; Chromatography, Gel; Copper; Copper Sulfate; Female; Ferrochelatase; Heme; Hexachlorobenzene; Hot Temperature; Liver; Pentachlorophenol; Porphyrias; Porphyrins; Protein Conformation; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Spectrophotometry | 1991 |
Hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: studies in lymphocytes and erythrocytes.
Topics: Adult; Aged; Erythrocytes; Female; Heme; Homozygote; Humans; Hydroxymethylbilane Synthase; Immunoelectrophoresis; Liver Diseases; Lymphocytes; Male; Middle Aged; Porphobilinogen Synthase; Porphyrias | 1991 |
Haem arginate in acute hereditary coproporphyria.
Topics: Arginine; Child; Coproporphyrins; Heme; Humans; Liver Diseases; Male; Porphyrias | 1991 |
Elevation of hormone-binding globulins in acute intermittent porphyria.
Topics: Adolescent; Adult; Aminolevulinic Acid; Arginine; Carrier Proteins; Heme; Humans; Hydrocortisone; Liver Diseases; Porphobilinogen; Porphyrias; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Thyroxine-Binding Proteins | 1990 |
Effects of haem arginate on variegate porphyria.
Topics: Adult; Arginine; Feces; Female; Heme; Humans; Infusions, Intravenous; Photosensitivity Disorders; Porphyrias; Protoporphyrins; Skin; Skin Diseases | 1990 |
Elevation of blood lactate and pyruvate levels in acute intermittent porphyria--a reflection of haem deficiency?
Topics: Adult; Blood Glucose; Female; Glucose; Heme; Humans; Lactates; Lactic Acid; Male; Porphyrias; Pyruvates; Pyruvic Acid | 1990 |
Ferrochelatase activity in human lymphocytes: effect of storage on haem formation.
Topics: Blood Specimen Collection; Ferrochelatase; Heme; Humans; Lyases; Lymphocytes; Mitogens; Porphyrias; Protoporphyria, Erythropoietic | 1990 |
[The coincidence of acute intermittent porphyria and Crohn's disease].
Topics: Acute Disease; Adult; Arginine; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Glucose; Heme; Humans; Male; Porphyrias; Propranolol; Quadriplegia; Remission Induction | 1990 |
Usefulness of chromatographic analysis of fecal porphyrins in the diagnosis of porphyrias.
Topics: Chromatography, Thin Layer; Coproporphyrins; Diagnosis, Differential; Feces; Heme; Humans; Porphyrias; Porphyrins; Skin Diseases | 1990 |
[Evaluation of porphyrinogenic effect of lindane in rats].
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Heme; Hexachlorocyclohexane; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
Acute hepatic heme depletion: impaired gluconeogenesis in rats.
Topics: Animals; Brain; Dicarbethoxydihydrocollidine; Gluconeogenesis; Glutathione; Glycerol; Heme; Hydroxyindoleacetic Acid; Liver; Phenobarbital; Porphyrias; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1989 |
New form of dual porphyria: coexistent acute intermittent porphyria and porphyria cutanea tarda.
Topics: Adult; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver Diseases; Male; Middle Aged; Porphyria, Acute Intermittent; Porphyrias; Skin Diseases; Uroporphyrinogen Decarboxylase | 1989 |
Changes of myocardial functions in acute hepatic porphyrias. Role of heme arginate administration.
Topics: Acute Disease; Adult; Arginine; Cytochrome c Group; Female; Heart; Heme; Humans; Liver Diseases; Male; Middle Aged; Porphyrias | 1989 |
Effect of ingestion of hemoproteins on fecal excretion of hemes and porphyrins.
Topics: Adolescent; Adult; Blood; Chromatography, High Pressure Liquid; Diet; Dietary Fiber; Feces; Heme; Hemeproteins; Humans; Meat Products; Porphyrias; Porphyrins; Reagent Kits, Diagnostic | 1989 |
Haem and porphyria attacks.
Topics: Arginine; Drug Evaluation; Heme; Humans; Porphyrias | 1989 |
Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria.
Topics: Acute Disease; Adult; Dose-Response Relationship, Drug; Female; Heme; Humans; Injections, Intramuscular; Liver Diseases; Male; Metalloporphyrins; Middle Aged; Photosensitivity Disorders; Porphyrias; Porphyrins; Protoporphyrins | 1989 |
Modulation of hepatic heme-binding Z protein in mice by the porphyrogenic carcinogens griseofulvin and hexachlorobenzene.
Topics: Animals; Blotting, Western; Carcinogens; Carrier Proteins; Chlorobenzenes; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Griseofulvin; Heme; Heme-Binding Proteins; Hemeproteins; Hexachlorobenzene; Liver; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Porphyrias | 1989 |
Interaction of chemicals with cytochrome P-450: implications for the porphyrinogenicity of drugs.
Topics: 5-Aminolevulinate Synthetase; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Cytochrome P-450 Enzyme System; Heme; Heterocyclic Compounds; Liver; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase | 1989 |
[Treatment of acute attacks of hepatic porphyrias with hematin].
Topics: Acute Disease; Heme; Hemin; Humans; Liver Diseases; Porphyrias | 1989 |
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Studies on their properties.
Topics: Animals; Chlorobenzenes; Enzyme Stability; Ferrochelatase; Heme; Hexachlorobenzene; Hydrogen-Ion Concentration; Lyases; Mitochondria, Liver; Porphyrias; Rats | 1989 |
Lack of effect of pregnancy or hematin therapy on erythrocyte porphobilinogen deaminase activity in acute intermittent porphyria.
Topics: Adult; Ammonia-Lyases; Erythrocytes; Female; Heme; Hemin; Humans; Hydroxymethylbilane Synthase; Porphyrias; Pregnancy; Pregnancy Complications | 1989 |
Optical and EPR spectroscopy studies on haem arginate, a new compound used for treatment of porphyria.
Topics: Arginine; Electron Spin Resonance Spectroscopy; Heme; Humans; Mathematics; Molecular Weight; Porphyrias | 1987 |
Effect of haem arginate therapy on porphyrin metabolism and mixed function oxygenase activity in acute hepatic porphyria.
Topics: Acute Disease; Adult; Antipyrine; Arginine; Cytochrome P-450 Enzyme System; Depression, Chemical; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver; Liver Diseases; Male; Mitochondria, Liver; Mixed Function Oxygenases; Porphobilinogen Synthase; Porphyrias; Porphyrins | 1987 |
Haem arginate: a new stable haem compound.
Topics: Animals; Arginine; Blood Coagulation; Blood Pressure; Drug Stability; Heme; Heme Oxygenase (Decyclizing); Hydrogen-Ion Concentration; Lethal Dose 50; Mice; Porphyrias; Spectrophotometry, Ultraviolet | 1987 |
The role of iron in the hexachlorobenzene induced porphyria. I. Studies on different types of iron and its relation with porphyrinogen carboxy-lyase decrease.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Disease Models, Animal; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1985 |
[Acute attacks of hepatic porphyria. Treatment with hematin. 5 cases].
Topics: Acute Disease; Adult; Heme; Hemin; Humans; Infusions, Intravenous; Liver Diseases; Porphyrias | 1986 |
[Efficacy and tolerability of a new hematin in the treatment of an acute attack of porphyria].
Topics: Acute Disease; Adolescent; Arginine; Female; Heme; Humans; Porphyrias | 1987 |
Haem arginate in acute hepatic porphyrias.
Topics: Acute Disease; Arginine; Heme; Humans; Liver Diseases; Porphyrias | 1986 |
The interaction of the factor VIII/von Willebrand factor complex with hematin.
Topics: Blood Platelets; Chromatography, Gel; Factor VIII; Heme; Hemin; Humans; Infusions, Intravenous; Iron Radioisotopes; Porphyrias; Protein Binding; Tritium; von Willebrand Factor | 1986 |
Renal transplantation for chronic renal failure in acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Cadaver; Enzyme Activation; Female; Heme; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Porphyrias; Rats; Rats, Inbred Strains | 1987 |
Haem arginate improves hepatic oxidative metabolism in variegate porphyria.
Topics: Adult; Antipyrine; Arginine; Feces; Female; Heme; Humans; Liver; Oxidation-Reduction; Porphyrias; Porphyrins | 1988 |
Treatment of acute hepatic porphyria with hematin.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Liver Diseases; Male; Middle Aged; Porphobilinogen; Porphyrias | 1988 |
Physiological roles of animal succinate thiokinases. Specific association of the guanine nucleotide-linked enzyme with haem biosynthesis.
Topics: Acyl Coenzyme A; Animals; Bone Marrow; Cattle; Chemical and Drug Induced Liver Injury; Coenzyme A Ligases; Dicarbethoxydihydrocollidine; Female; Gallbladder; Guanosine Triphosphate; Heme; Liver Diseases; Mice; Mitochondria, Liver; Porphyrias; Succinate-CoA Ligases | 1988 |
Lead effects on the heme biosynthetic pathway. Relationship to toxicity.
Topics: Aminolevulinic Acid; Antipyrine; Cytochromes; Heme; Humans; Lead Poisoning; Models, Biological; Porphyrias; Porphyrins | 1987 |
Drug-induced modulations of hepatic heme metabolism. Neurological consequences.
Topics: Animals; Brain; Gastric Emptying; Gluconeogenesis; Heme; Intestine, Small; Liver; Liver Diseases; Models, Biological; Porphyrias; Pyrimethamine; Rats; Serotonin; Tryptophan | 1987 |
Porphyrin metabolism and haem biosynthesis in Gilbert's syndrome.
Topics: 5-Aminolevulinate Synthetase; Adult; Bilirubin; Female; Flavoproteins; Gilbert Disease; Heme; Humans; Hyperbilirubinemia, Hereditary; Male; Middle Aged; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphyrias; Porphyrins; Protoporphyrinogen Oxidase; Rifampin | 1987 |
The effect of hemin in vitro and in vivo on human erythroid progenitor cells.
Topics: Adult; Anemia, Sickle Cell; Colony-Forming Units Assay; Erythropoiesis; Female; Globins; Hematopoietic Stem Cells; Heme; Hemin; Humans; Male; Porphyrias | 1987 |
Acute intermittent porphyria: the first case report in Malaysia.
Topics: Acute Disease; Adult; Female; Heme; Humans; Malaysia; Porphobilinogen; Porphyrias | 1986 |
Studies on the role of iron in the alterations observed in hexachlorobenzene-induced porphyria.
Topics: Animals; Carboxy-Lyases; Chelating Agents; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Porphyrias; Rats; Rats, Inbred Strains | 1986 |
[Treatment of acute intermittent porphyria with a new protein-bound lyophilized hematin].
Topics: Acute Disease; Adult; Female; Freeze Drying; Heme; Hemin; Humans; Porphobilinogen; Porphyrias; Protein Binding | 1987 |
In inherited porphyrias, lead intoxication is a toxogenetic disorder.
Topics: Heme; Humans; Lead; Lead Poisoning; Porphobilinogen Synthase; Porphyrias | 1987 |
The effects of haem arginate and haematin upon the allylisopropylacetamide induced experimental porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Arginine; Heme; Hemin; Liver; Male; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains | 1987 |
[Treatment of acute intermittent porphyria. The first use of Heme-arginate in Czechoslovakia].
Topics: Acute Disease; Adult; Arginine; Heme; Humans; Male; Middle Aged; Porphyrias | 1987 |
[Definition and classification of porphyrias].
Topics: Heme; Humans; Liver Diseases; Porphyrias; Porphyrinogens; Skin Diseases | 1987 |
Effect of decreased ferrochelatase activity on iron and porphyrin content in mitochondria of mice with porphyria induced by griseofulvin.
Topics: Animals; Chemical and Drug Induced Liver Injury; Griseofulvin; Heme; Iron; Liver Diseases; Lyases; Mice; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Porphyrias; Porphyrins; Protoporphyria, Erythropoietic | 1986 |
Instability of hematin used in the treatment of acute hepatic porphyria.
Topics: Acute Disease; Adult; Animals; Anticoagulants; Drug Stability; Female; Freeze Drying; Heme; Hemin; Humans; Liver Diseases; Male; Porphyrias; Rats; Rats, Inbred Strains; Spectrophotometry; Temperature; Time Factors | 1986 |
[A new drug for porphyria].
Topics: Arginine; Heme; Humans; Porphyrias | 1986 |
Circulatory collapse associated with hemin therapy for acute intermittent porphyria.
Topics: Female; Heme; Hemin; Humans; Middle Aged; Porphyrias; Vascular Diseases | 1986 |
Microsomal enzyme induction and heme synthesis abnormalities may offer new indicators for biological monitoring in occupational and environmental medicine.
Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Environmental Monitoring; Enzyme Induction; Heme; Humans; Microsomes, Liver; Occupational Diseases; Porphyrias; Porphyrins | 1986 |
Pharmacokinetics of intravenously administered haem arginate.
Topics: Adult; Arginine; Female; Haptoglobins; Heme; Hemopexin; Humans; Injections, Intravenous; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Porphyrias | 1986 |
Porphyria. Basic science aspects.
Topics: 5-Aminolevulinate Synthetase; Bone Marrow; Complement Activation; Heme; Humans; Lipid Metabolism; Liver; Models, Biological; Porphyrias; Porphyrinogens; Porphyrins; Skin Diseases; Uroporphyrinogens | 1986 |
The erythropoietic porphyrias.
Topics: Diagnosis, Differential; Erythropoiesis; Female; Heme; Humans; Liver Function Tests; Male; Photosensitivity Disorders; Porphyrias; Protoporphyrins; Skin | 1986 |
Elevated brain tryptophan and enhanced 5-hydroxytryptamine turnover in acute hepatic heme deficiency: clinical implications.
Topics: Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Heme; Liver; Liver Diseases; Male; Morphine; Porphyrias; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1985 |
Hepatocarcinogenicity of hexachlorobenzene in rats and the sex difference in hepatic iron status and development of porphyria.
Topics: Animals; Chlorobenzenes; Female; Heme; Hexachlorobenzene; Iron; Kidney; Liver; Liver Neoplasms, Experimental; Male; Porphyrias; Porphyrins; Rats; Rats, Inbred F344; Sex Factors; Uroporphyrinogen Decarboxylase | 1985 |
Hematin therapy in acute porphyria.
Topics: Female; Glucose; Heme; Hemin; Humans; Porphyrias; Pregnancy; Pregnancy Complications | 1985 |
Effects of polyhalogenated aromatic compounds on porphyrin metabolism.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Heme; Humans; Hydrocarbons, Halogenated; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase | 1985 |
"Glucose effect" and rate limiting function of uroporphyrinogen synthase on porphyrin metabolism in hepatocyte culture: relationship with human acute hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Cells, Cultured; Chick Embryo; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Kinetics; Liver; Liver Diseases; Meprobamate; Porphobilinogen; Porphyrias; Porphyrins | 1985 |
Cadmium as an inducer of chemical porphyria in chick embryo.
Topics: 5-Aminolevulinate Synthetase; Animals; Cadmium; Chick Embryo; Heme; Liver; Porphobilinogen Synthase; Porphyrias | 1985 |
Prevention and treatment of acute porphyric attacks.
Topics: Acute Disease; Female; Glucose; Heme; Hemin; Humans; Liver Diseases; Porphyrias; Recurrence | 1985 |
Pharmacogenetics and porphyria.
Topics: Acetamides; Amides; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Esters; Heme; Liver; Pharmacogenetics; Porphyrias; Porphyrins; Pyridines | 1971 |
Identification of a group of tetracarboxylate porphyrins, containing one acetate and three propionate -substituents, in faeces from patients with symptomatic cutaneous hepatic porphyria and from rats with porphyria due to hexachlorobenzene.
Topics: Acetates; Animals; Carboxylic Acids; Chromatography, Thin Layer; Feces; Female; Heme; Hexachlorocyclohexane; Humans; Hydrolysis; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Porphyrias; Porphyrins; Propionates; Rats; Spectrophotometry | 1972 |
Prophyrin metabolism in experimental hepatic siderosis in the rat. II. Combined effect of iron overload and hexachlorobenzene.
Topics: 5-Aminolevulinate Synthetase; Animals; Chromatography, Thin Layer; Female; Heme; Hexachlorocyclohexane; Iron-Dextran Complex; Liver; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats; Siderosis | 1972 |
Porphyrin metabolism in experimental hepatic siderosis in the rat. 3. Effect of iron overload and hexachlorobenzene on liver haem biosynthesis.
Topics: Animals; Benzene Derivatives; Carbon Isotopes; Carboxy-Lyases; Chlorine; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Hexachlorocyclohexane; Insecticides; Iron; Liver; NAD; Oxidation-Reduction; Plants; Porphyrias; Rats; Siderosis; Succinates | 1972 |
Chemical porphyria in Japanese quail (Coturnix c. Japonica).
Topics: Allylisopropylacetamide; Animals; Bile; Biphenyl Compounds; Bromine; Coturnix; Dicarboxylic Acids; Environmental Pollution; Feedback; Female; Glutamate Dehydrogenase; Heme; Hexachlorocyclohexane; Kidney; Liver; Male; Mitochondria, Liver; Polychlorinated Biphenyls; Porphyrias; Porphyrins; Pyridines; Spectrometry, Fluorescence; Time Factors | 1973 |
Aetiological relationship between hepatic siderosis and symptomatic porphyria cutanea tarda. Evidence based on work in Durban.
Topics: 5-Aminolevulinate Synthetase; Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Cytochromes; Glutathione; Heme; Hexachlorocyclohexane; Iron; Iron-Dextran Complex; Lactates; Liver; Liver Diseases; Microsomes, Liver; Oxidation-Reduction; Porphyrias; Porphyrins; Pyruvates; Rats; Siderosis; Succinates; Time Factors | 1973 |
Metabolic anomalies in porphyria. The result of impaired biological oxidation?
Topics: Adenosine Triphosphate; Dicarboxylic Acids; Fatty Acids; Glycolysis; Heme; Humans; Metabolic Diseases; Oxidative Phosphorylation; Porphyrias | 1967 |
Biotransformation in the liver: implications for human disease.
Topics: Animals; Biotransformation; Cytochromes; Dicumarol; Griseofulvin; Heme; Humans; Liver; Microsomes; Pharmaceutical Preparations; Phenytoin; Porphyrias; Rats | 1968 |
Enzyme induction and haem biosynthesis.
Topics: Animals; Dehydroepiandrosterone; Enzyme Induction; Heme; Humans; Hydro-Lyases; Porphyrias; Rats | 1970 |
Biochemical changes in liver mitochondria of rats treated with 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethyl-pyridine.
Topics: Acyltransferases; Animals; Catalase; Electron Transport Complex IV; Glutamates; Heme; In Vitro Techniques; Levulinic Acids; Liver; Lyases; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Porphyrias; Porphyrins; Rats; Succinates; Uncoupling Agents | 1970 |
Distribution of some possible intermediates of the haem biosynthesis.
Topics: Adult; Animals; Animals, Newborn; Bile; Bone Marrow; Carcinoma, Hepatocellular; Cattle; Countercurrent Distribution; Cricetinae; Duodenum; Feces; Female; Germ-Free Life; Heart; Heme; Humans; Infant, Newborn; Intestinal Secretions; Lacrimal Apparatus; Liver; Liver Neoplasms; Male; Meconium; Porphyrias; Porphyrins; Rhodobacter sphaeroides; Swine | 1974 |
Glucose effect on tryptophan oxygenase and tyrosine aminotransferase induction after allylisopropylacetamide-induced porphyria in the rat.
Topics: Acetamides; Adrenalectomy; Allyl Compounds; Animals; Body Weight; Diet; Enzyme Induction; Female; Glucose; Heme; Liver; Organ Size; Porphyrias; Rats; Time Factors; Tryptophan Oxygenase; Tyrosine Transaminase | 1970 |
[Intermittent acuteporphyria. Clinical significance of reduced activity of uroporphyrinogen-I-synthetase].
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Animals; Chlorides; Enzyme Induction; Heme; Lead; Liver; Lyases; Metabolism, Inborn Errors; Porphyrias; Rats | 1974 |
Repression by hematin of porphyrin biosynthesis in erythrocyte precursors in congenital erythropoietic porphyria.
Topics: Adult; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Depression, Chemical; Erythrocytes; Erythropoiesis; Feedback; Female; Heme; Humans; Porphyrias; Porphyrins | 1974 |
Comparative aspects of porphyria in man and animals.
Topics: Adult; Aminolevulinic Acid; Animals; Cattle; Drug Stability; Female; Genes, Recessive; Heme; Heterozygote; Hot Temperature; Humans; Isomerases; Kinetics; Male; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Reticulocytes; Sciuridae | 1974 |
Isotopic studies of porphyrin and heme metabolism: bonanzas and pitfalls.
Topics: Aminolevulinic Acid; Anemia, Hemolytic; Antimetabolites; Bilirubin; Carbon Radioisotopes; Erythrocytes; Feces; Glycine; Hematocrit; Heme; Hemoglobins; Humans; Iron; Iron Radioisotopes; Isotope Labeling; Jaundice; Methods; Nitrogen Isotopes; Phagocytosis; Phenylhydrazines; Porphyrias; Porphyrins; Reticulocytes; Time Factors; Tritium | 1974 |
-Aminolevulinic acid synthetase activity of human bone marrow erythroid cells in various hematological disorders.
Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Coenzyme A; Edetic Acid; Erythrocytes; Glycine; Hematologic Diseases; Hematopoietic Stem Cells; Heme; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Levulinic Acids; Magnesium; Porphyrias; Pyridoxal Phosphate; Thalassemia | 1972 |
Quantitative studies of the delivery of hepatic-synthesized bilirubin to plasma utilizing -aminolevulinic acid-4- 14 C and bilirubin- 3 H in man.
Topics: Adult; Bile Pigments; Bilirubin; Carbon Isotopes; Chromium Isotopes; Feces; Hematocrit; Heme; Humans; Injections, Intravenous; Levulinic Acids; Liver; Mathematics; Methods; Porphobilinogen; Porphyrias; Porphyrins; Time Factors; Tritium | 1972 |
Effect of hexachlorobenzene on haem synthesis.
Topics: 5-Aminolevulinate Synthetase; Amino Acids; Animals; Benzene Derivatives; Cells, Cultured; Chlorine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life; Heme; Hydro-Lyases; In Vitro Techniques; Insecticides; Liver; Microsomes, Liver; Organ Size; Plants; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1972 |
Intermittent acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Heme; Humans; Porphyrias; Porphyrins; Remission, Spontaneous | 1972 |
The effects of drugs on the activities of 5-aminolaevulinate synthetase and other enzymes in the pathway of haem biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Dicarboxylic Acids; Esters; Griseofulvin; Heme; Liver; Mice; Phenobarbital; Phenylbutazone; Porphyrias; Pyridines; Rats | 1972 |
Structure and synthesis of heme and references to globin synthesis.
Topics: 5-Aminolevulinate Synthetase; Globins; Heme; Iron; Levulinic Acids; Metabolism, Inborn Errors; Peptide Chain Initiation, Translational; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins; Protein Conformation | 1972 |
[Clinically important disorders of heme synthesis].
Topics: 5-Aminolevulinate Synthetase; Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Erythrocytes; Heme; Humans; Iron; Porphobilinogen; Porphyrias; Porphyrins | 1972 |
Hereditary hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Cytochrome P-450 Enzyme System; Erythrocytes; Heme; Humans; Liver; Microsomes, Liver; Porphobilinogen; Porphyrias | 1973 |
Studies on hepatic -aminolevulinic acid synthetase.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Carbon Isotopes; Citrates; Coenzyme A; Enzyme Induction; Freezing; Heme; Ketoglutaric Acids; Male; Membranes; Microsomes, Liver; Mitochondria, Liver; Picolines; Porphyrias; Rats; Subcellular Fractions; Succinates; Vibration | 1973 |
Effect of hematin in acute porphyric relapse.
Topics: 5-Aminolevulinate Synthetase; Adult; Alcohol Drinking; Heme; Humans; Injections, Intravenous; Male; Porphobilinogen; Porphyrias; Porphyrins; Substance-Related Disorders | 1973 |
[The hepatic porphyrias].
Topics: 5-Aminolevulinate Synthetase; Fasting; Glucose; Heme; Humans; Lead Poisoning; Levulinic Acids; Liver Cirrhosis; Liver Diseases; Male; Photosensitivity Disorders; Porphyrias; Porphyrins | 1973 |
Congenital erythropoietic porphyria with a hitherto undescribed porphyrin pattern.
Topics: Anemia, Hemolytic; Bone Marrow Diseases; Chromatography, Paper; Erythrocytes; Erythropoiesis; Feces; Heme; Humans; Infant; Male; Photosensitivity Disorders; Porphyrias; Porphyrins; Syndrome | 1973 |
Decreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and mice.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Dicarboxylic Acids; Heme; Iron; Iron Radioisotopes; Levulinic Acids; Liver Diseases; Lyases; Male; Mice; Mitochondria, Liver; Porphyrias; Porphyrins; Proadifen; Pyridines; Rats; Species Specificity | 1973 |
Intermittent acute porphyria. Clinical and biochemical studies of disordered heme biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Animals; Carbon Radioisotopes; Cells, Cultured; Child; Child, Preschool; Chromatography, Ion Exchange; Erythrocytes; Fibroblasts; Heme; Humans; Hydro-Lyases; Infant; Kinetics; Liver; Porphyrias; Porphyrins; Rats; Spectrometry, Fluorescence; Temperature | 1973 |
Enzymatic defects in hepatic porphyria. Preliminary observations in patients with porphyria cutanea tarda and variegate porphyria.
Topics: 5-Aminolevulinate Synthetase; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Heme; Humans; Iron; Liver; Liver Diseases; Lyases; Mitochondria, Muscle; Muscles; Porphyrias; Porphyrins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Succinates; Time Factors | 1973 |
The effects of chemical porphyrogens and drugs on the activity of rat liver tryptophan pyrrolase.
Topics: Acetamides; Allylisopropylacetamide; Animals; Apoproteins; Cytochrome P-450 Enzyme System; Dicarboxylic Acids; Griseofulvin; Heme; Humans; Hydrocortisone; Levulinic Acids; Liver; Male; Mental Disorders; Microsomes; Phenobarbital; Phenylbutazone; Porphyrias; Proadifen; Protein Precursors; Pyridines; Rats; Starvation; Time Factors; Tryptophan; Tryptophan Oxygenase | 1973 |
Hemopexin metabolism in sickle-cell disease, porphyrias and control subjects--effects of heme injection.
Topics: Anemia, Sickle Cell; Erythropoiesis; Half-Life; Heme; Hemopexin; Humans; Injections, Intravenous; Iodine Radioisotopes; Middle Aged; Porphyrias; Skin Manifestations; Time Factors | 1974 |
[Delta-aminolevulinic acid in physiological conditions and some diseases in children].
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Child; Citric Acid Cycle; Heme; Humans; Levulinic Acids; Porphyrias; Porphyrins | 1974 |
Decreased levels of cytochrome P-450 and catalase in hepatic porphyria caused by substituted acetamides and barbiturates. Importance of the allyl group in the molecule of the active drugs.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetates; Allyl Compounds; Amides; Animals; Barbiturates; Catalase; Chemical and Drug Induced Liver Injury; Cytochromes; Female; Heme; Liver; Liver Diseases; Porphyrias; Porphyrins; Rats; Structure-Activity Relationship | 1972 |
The induction of -aminolevulinic acid synthetase in cultured liver cells. The effects of end product and inhibitors of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetates; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Repression; Heme; Humans; Iron; Iron Isotopes; Kinetics; Lead; Levulinic Acids; Liver; Porphyrias; Succinates; Tritium | 1972 |
Stimulation of liver 5-aminolaevulinate synthetase by drugs and its relevance to drug-induced accumulation of cytochrome P-450. Studies with phenylbutazone and 3,5-diethoxycarbonyl-1,4-dihydrocollidine.
Topics: 5-Aminolevulinate Synthetase; Animals; Cytochromes; Dicarboxylic Acids; Enzyme Induction; Esters; Heme; Iron Isotopes; Liver; Male; Phenylbutazone; Porphyrias; Pyridines; Rats | 1972 |
Porphyria cutanea tarda.
Topics: Alcohol Drinking; Alopecia; Aspartate Aminotransferases; Female; Heme; Humans; Liver; Male; Middle Aged; Photosensitivity Disorders; Pigmentation Disorders; Porphyrias | 1972 |
Purification and properties of solubilized mitochondrial -aminolevulinic acid synthetase and comparison with the cytosol enzyme.
Topics: 5-Aminolevulinate Synthetase; Acetyltransferases; Aminobutyrates; Animals; Antibodies; Chromatography, Affinity; Chromatography, Gel; Cross Reactions; Cytoplasm; Dithiothreitol; Freeze Drying; Guinea Pigs; Heme; Keto Acids; Liver; Macromolecular Substances; Mitochondria, Liver; Molecular Weight; Porphyrias; Rabbits; Rats; Sodium Chloride; Vibration | 1972 |
Erythropoietic defects in protoporphyria: a study of factors involved in labelling of porphyrins and bile pigments from ALA- 3 H and glycine- 14 C.
Topics: Adult; Autoradiography; Bile Pigments; Carbon Isotopes; Erythrocytes; Erythropoiesis; Glycine; Heme; Humans; Levulinic Acids; Ligases; Male; Methods; Middle Aged; Porphyrias; Porphyrins; Time Factors; Tritium; Urobilin; Urobilinogen | 1971 |
The measurement of the synthetic rate of bilirubin from hepatic hemes in patients with acute intermittent porphyria.
Topics: Acute Disease; Adult; Amino Acids; Bilirubin; Carbon Isotopes; Female; Heme; Humans; Levulinic Acids; Liver; Male; Porphyrias; Propionates; Pyrroles; Spectrophotometry; Tritium | 1971 |
Erythrocyte protoporphyrin and iron uptake in erythropoietic protoporphyria.
Topics: Adolescent; Adult; Erythrocytes; Erythropoiesis; Female; Heme; Humans; In Vitro Techniques; Iron; Iron Isotopes; Male; Microscopy, Fluorescence; Middle Aged; Porphyrias; Porphyrins | 1971 |
Erythrocyte porphyrin and erythrocyte survival in bovine erythropoietic porphyria.
Topics: Animals; Carbon Isotopes; Cattle; Cattle Diseases; Cell Survival; Erythrocytes; Glycine; Heme; Injections, Intravenous; Methods; Porphyrias; Porphyrins; Time Factors | 1971 |
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide.
Topics: Acetamides; Allyl Compounds; Amides; Amino Acids; Animals; Carbon Isotopes; Cytochromes; Enzyme Induction; Heme; Iron Isotopes; Levulinic Acids; Ligases; Liver; Male; Microsomes, Liver; Phenobarbital; Pigments, Biological; Porphyrias; Proadifen; Rats; Tritium | 1971 |
Drug-induced porphyrin biosynthesis. 3. Inhibition of drug-induced porphyria by protohemin.
Topics: Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Depression, Chemical; Glutarates; Glutethimide; Griseofulvin; Heme; Liver; Phthalic Acids; Porphyrias; Porphyrins; Pyridines | 1971 |
Porphyrin synthesis in drug induced hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allyl Compounds; Amino Acids; Animals; Dicarboxylic Acids; Esters; Heme; Hydro-Lyases; Iron; Iron Isotopes; Levulinic Acids; Liver; Male; Mice; Porphyrias; Porphyrins; Propionates; Pyridines; Pyrroles; Rats | 1971 |
Acute intermittent porphyria: studies of the enzymatic basis of disordered haem biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Acyltransferases; Animals; Birds; Heme; Humans; In Vitro Techniques; Liver; Lyases; Porphobilinogen; Porphyrias; Porphyrins | 1971 |
Drugs and porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Animals; Barbiturates; Chick Embryo; Cytochromes; Griseofulvin; Heme; Liver; Male; Mice; Microsomes, Liver; Mitochondria, Liver; Phenylbutazone; Porphyrias; Porphyrins; Pyridines; Rats | 1971 |
Porphyrin biosynthesis. Enhancement of the fractional catabolic rate of microsomal haem in chemically induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Carbon Isotopes; Cytochromes; Enzyme Induction; Heme; Iron Isotopes; Liver; Male; Microsomes, Liver; Phenobarbital; Porphyrias; Porphyrins; Rats; Tritium | 1971 |
Ferrokinetics in symptomatic porphyria.
Topics: Alcoholism; Chromium Isotopes; Erythrocyte Count; Feces; Heme; Humans; Iron; Iron Isotopes; Kinetics; Liver Function Tests; Porphyrias; Porphyrins | 1971 |
Experimental porphyria. II. Drug-induced porphyrin biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Alkenes; Allyl Compounds; Amides; Animals; Barbiturates; Chemical Phenomena; Chemistry; Chick Embryo; Cytochromes; Enzyme Induction; Esters; Female; Heme; Hydrolysis; Hypnotics and Sedatives; Liver; Male; Porphyrias; Porphyrins; Pregnanes; Pyridines; Sterols; Urea | 1971 |
Effect of alkylating agents on haem metabolism.
Topics: Adenosine Triphosphate; Alkylating Agents; Animals; Busulfan; Chlorambucil; Cyclophosphamide; Feces; Female; Heme; Liver; Methandrostenolone; Porphyrias; Porphyrins; Rabbits; Rats | 1971 |
Porphyrin and haem biosynthesis and its control.
Topics: Animals; Coenzymes; Enzyme Repression; Enzymes; Feedback; Heme; Humans; In Vitro Techniques; Ligases; Mitochondria; Oxidation-Reduction; Oxygen; Porphyrias; Porphyrins | 1966 |
Accumulation of iron in mitochondria of erythroblasts.
Topics: Anemia, Hemolytic; Anemia, Sideroblastic; Bone Marrow Examination; Chloramphenicol; Erythrocytes; Globins; Heme; Humans; Iron; Lead Poisoning; Leukemia, Erythroblastic, Acute; Microscopy, Electron; Mitochondria; Porphyrias; Thalassemia | 1967 |
Soluble hepatic delta-aminolevulinic acid synthetase: end-product inhibition of the partially purified enzyme.
Topics: Acyltransferases; Amino Acids; Animals; Chromatography; Heme; Levulinic Acids; Ligases; Liver; Methods; Mitochondria, Liver; Porphyrias; Rats; Succinates | 1969 |
Experimental hepatic porphyria: studies with steroids of physiological origin in man.
Topics: Animals; Antibiotics, Antineoplastic; Chemical and Drug Induced Liver Injury; Chick Embryo; Culture Techniques; Glucocorticoids; Glucose; Glucuronates; Heme; Liver; Models, Biological; Models, Chemical; Nucleic Acids; Organometallic Compounds; Phosphates; Porphyrias; Porphyrins; Protein Biosynthesis; Uridine | 1968 |
Heme biosynthesis in intermittent acute prophyria: decreased hepatic conversion of porphobilinogen to porphyrins and increased delta aminolevulinic acid synthetase activity.
Topics: Acyltransferases; Animals; Carbon Isotopes; Culture Techniques; Erythrocytes; Heme; Humans; Levulinic Acids; Liver; Mice; Porphyrias; Porphyrins; Succinates | 1970 |
Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusions of hematin.
Topics: Adult; Amino Acids; Female; Heme; Humans; Injections, Intravenous; Levulinic Acids; Porphyrias; Porphyrins; Propionates; Pyrroles; Time Factors | 1971 |
Carbon monoxide production and heme catabolism.
Topics: Acetamides; Allyl Compounds; Anemia, Sideroblastic; Animals; Bile Pigments; Bone Marrow; Carbon Isotopes; Carbon Monoxide; Dogs; Erythrocytes; Erythropoiesis; Glycine; Heme; Hemoglobins; Humans; Levulinic Acids; Liver; Mononuclear Phagocyte System; Phenobarbital; Porphyrias; Reticulocytes; Time Factors | 1970 |
[Excretion of gamma delta-dioxovalerianic acid and delta-aminolaevulinic acid in various disorders of haem synthess].
Topics: Acute Disease; Amino Acids; Chronic Disease; Heme; Humans; Lead Poisoning; Levulinic Acids; Porphyrias; Valerates | 1969 |
[Porphyrin analysis from liver cylinders in late cutaneous porphyria].
Topics: Biopsy; Chromatography, Thin Layer; Heme; Humans; Liver; Methods; Porphyrias; Porphyrins | 1969 |
[Common physiopathologic manifestations of diseases associated with vitiligo].
Topics: Anemia, Pernicious; Erythropoiesis; Heme; Hemoglobins; Melanocyte-Stimulating Hormones; Porphyrias; Vitiligo | 1969 |
Porphyrins and porphyrias: new horizons.
Topics: Anemia, Sideroblastic; Heme; India; Metabolic Diseases; Metabolism, Inborn Errors; Porphyrias; Porphyrins; Pyrroles | 1969 |
Defects in haem synthesis in mammalian tissues in experimental lead poisoning and experimental porphyria.
Topics: Amides; Animals; Bone Marrow; Brain; Female; Heme; Hydro-Lyases; Kidney; Lead Poisoning; Levulinic Acids; Ligases; Liver; Porphyrias; Porphyrins; Pyrroles; Rabbits | 1970 |
Biochemical defects in two types of human hepatic porphyria.
Topics: Acyltransferases; Adult; Feces; Feedback; Heme; Humans; Hydro-Lyases; Levulinic Acids; Liver; Lyases; Male; Porphyrias; Porphyrins; Succinates | 1970 |
Permeability properties of mitochondrial membranes and the regulation of haem biosynthesis.
Topics: Acyltransferases; Amino Acids; Animals; Carbon Isotopes; Glycine; Heme; Levulinic Acids; Lyases; Membranes; Mitochondria, Liver; Permeability; Porphyrias; Rats; Succinates; Tritium; Vibration | 1970 |
Porphyria: the little mimic. An interesting case with a general review.
Topics: Biliary Tract Diseases; Diagnosis, Differential; Female; Heme; Humans; Liver Diseases; Male; Middle Aged; Neurologic Manifestations; Porphyrias | 1970 |
Chemically induced porphyria: increased microsomal heme turnover after treatment with allylisopropylacetamide.
Topics: Acetates; Acyltransferases; Amides; Animals; Cytochromes; Enzyme Induction; Heme; Levulinic Acids; Male; Microsomes, Liver; Porphyrias; Rats; Tritium | 1971 |
Hepatic porphyrias.
Topics: Amino Acids; Chromosome Aberrations; Chromosome Disorders; Heme; Humans; Levulinic Acids; Ligases; Liver; Liver Diseases; Porphyrias | 1971 |
[Differentiation of hepatic porphyrinurias].
Topics: Adult; Chromatography, Thin Layer; Enzyme Induction; Fatty Liver; Female; Fluorometry; Heme; Humans; Hydro-Lyases; Levulinic Acids; Liver; Liver Cirrhosis; Male; Middle Aged; Porphyrias; Porphyrins; Spectrophotometry | 1971 |
[Symposium on clinical aspects on porphyrias. (4). The role of citric acid cycle turnover in the control of heme biosynthesis].
Topics: Animals; Citric Acid Cycle; Heme; Mice; Mitochondria, Liver; Porphyrias | 1967 |
The metabolism of (5-14C)delta-aminolaevulic acid in normal and porphyric human subjects.
Topics: Adult; Bilirubin; Carbon Dioxide; Carbon Isotopes; Female; Heme; Humans; Hydro-Lyases; Levulinic Acids; Liver; Male; Middle Aged; Porphyrias; Porphyrins; Uric Acid | 1968 |
Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Blood Proteins; Child; Haptoglobins; Heme; Hemoglobinuria, Paroxysmal; Humans; Middle Aged; Myoglobinuria; Porphyrias; Spherocytosis, Hereditary; Thalassemia | 1968 |
Studies in endocrine pharmacology. Biologic actions of some natural steroids on the liver.
Topics: Culture Techniques; Estradiol; Estriol; Female; Heme; Humans; Liver; Liver Function Tests; Porphyrias; Porphyrins; Pregnancy; Steroids | 1968 |
Cytochrome C in the treatment of porphyria.
Topics: Adult; Cytochromes; Female; Heme; Humans; Pentobarbital; Porphyrias; Quadriplegia | 1968 |
The regulation of porphyrin and heme synthesis.
Topics: Acyltransferases; Heme; Levulinic Acids; Porphyrias; Porphyrins; Succinates | 1968 |
Lead poisoning as a disorder of heme synthesis.
Topics: Acyltransferases; Child; Feces; Heme; Humans; Hydro-Lyases; Iron Isotopes; Lead Poisoning; Levulinic Acids; Porphyrias; Porphyrins | 1968 |
Sideroblastic anemia with dermal photosensitivity and greatly increased erythrocyte protoporphyrin.
Topics: Aged; Anemia, Hemolytic; Anemia, Sideroblastic; Blood Cell Count; Catalase; Diagnosis, Differential; Erythrocytes; Feces; Heme; Humans; Iron; Ligases; Male; Photosensitivity Disorders; Porphyrias; Porphyrins; Reticulocytes | 1969 |
Porphyria in the adolescent--diagnosis and treatment.
Topics: Adolescent; Female; Genes, Dominant; Heme; Humans; Male; Pedigree; Porphyrias; Porphyrins; Vasopressins | 1969 |
Heme and porphyrin synthesis by porphyric bovine erythrocytes.
Topics: Anemia; Animals; Cattle; Chromatography; Erythrocytes; Glycine; Heme; In Vitro Techniques; Levulinic Acids; Porphyrias; Porphyrins; Spectrophotometry | 1965 |
[Physiology and pathology of heme synthesis].
Topics: Anemia, Hypochromic; Anemia, Sideroblastic; Biochemical Phenomena; Biochemistry; Erythrocytes; Erythropoiesis; Heme; Hemoglobins; Humans; Lead Poisoning; Porphyrias | 1964 |
[The clinical picture of erythropathies].
Topics: Anemia, Hemolytic, Congenital; Anemia, Macrocytic; Anemia, Sickle Cell; Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Hematologic Diseases; Heme; Humans; Methemoglobinemia; Porphyrias; Spherocytosis, Hereditary; Thalassemia | 1964 |
Rate of heme and porphyrin synthesis by bovine porphyric reticulocytes in vitro.
Topics: Animals; Carbon Isotopes; Cattle; Cattle Diseases; Glycine; Heme; In Vitro Techniques; Porphyrias; Porphyrins; Reticulocytes | 1966 |