heme has been researched along with Innate Inflammatory Response in 147 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.40) | 18.7374 |
| 1990's | 3 (2.04) | 18.2507 |
| 2000's | 30 (20.41) | 29.6817 |
| 2010's | 66 (44.90) | 24.3611 |
| 2020's | 43 (29.25) | 2.80 |
| Authors | Studies |
|---|---|
| Atif, SM; Callahan, RC; Cartwright, IM; Colgan, SP; Fontenot, AP; Onyiah, JC; Orlicky, DJ; Schaefer, REM | 1 |
| Chen, Y; Harypursat, V; Lu, Y; Ouyang, J; Yang, S | 1 |
| Ek, J; Hagberg, H; Nilsson, G; Rocha-Ferreira, E; Song, J; Wang, X; Wang, Y; Xu, Y; Zelco, A; Zhang, S; Zhang, X; Zhu, C | 1 |
| Bhadauria, M; Nirala, SK; Rakshit, S; Sahu, N | 1 |
| Abdulla, F; Belcher, JD; Chen, C; Conglin, R; Cummings, J; Dudler, T; Ivy, ZK; Nguyen, J; Vercellotti, GM | 1 |
| Cortegano, I; de Andrés, B; Egido, J; García-Caballero, C; Gaspar, ML; González-Guerrero, C; Guerrero-Hue, M; Herencia, C; Moreno, JA; Morgado-Pascual, JL; Opazo-Rios, L; Rayego-Mateos, S; Vallejo-Mudarra, M; Vázquez-Carballo, C | 1 |
| Igase, M; Iwatani, N; Mizukami, Y; Mizuno, T; Sakai, A; Watanabe, K | 1 |
| Allali, S; Bouceba, T; de Montalembert, M; Hermine, O; Maciel, TT; Rignault-Bricard, R; Taylor, M | 1 |
| Anum, SJ; Bolívar, BE; Bouchier-Hayes, L; Flanagan, JM; Salgar, S | 1 |
| Chen, W; Liang, Z; Luo, X; Lv, M; Ma, H; Pan, C; Parveen, S; Ruan, Q; Shafique, L; Wang, W | 1 |
| Chambliss, C; Gee, BE; Stiles, JK | 1 |
| Chen, H; Huang, Y; Lin, J; Lin, L; Qin, Z; Tang, Y; Wei, L; Yang, M; Yang, S; Yao, M | 1 |
| Bashi, A; Botchway, F; Driss, A; Harp, KO; Hood, JL; Stiles, JK; Thomas, JJ; Thompson, WE; Wilson, MD | 1 |
| Bloch, W; Demirbas, A; Deschner, J; Korkmaz, Y; Plomann, M; Puladi, B | 1 |
| An, X; Antypiuk, A; Cox, JE; Manwani, D; Pearce, Q; Sharma, R; Vance, SZ; Vinchi, F; Yazdanbakhsh, K | 1 |
| Bosco, M; Chaiworapongsa, T; Gallo, DM; Gotsch, F; Jaiman, S; Jung, E; Ramón Y Cajal, CL; Romero, R; Suksai, M; Yoon, BH | 1 |
| Janke, LJ; Kanneganti, TD; Karki, R; Kim, HJ; Malireddi, RKS; Mall, R; Pandian, N; Sarkar, R; Sundaram, B; Vogel, P; Wang, Y | 1 |
| Cain, MD; Du, D; Goldberg, DE; Klein, RS; Nguyen, ST; Russo, I; Wu, Q; Wychrij, D | 1 |
| Dimitrov, JD; Perrella, G; Rayes, J; Roumenina, LT | 1 |
| Asokan, S; Csizmadia, E; Glickman, J; Janikova, M; Janovicova, L; O'Connell, M; Robson, SC; Seika, P; Wegiel, B | 1 |
| Henkel, FDR; O'Neill, LAJ | 1 |
| Bernard, EM; Broz, P | 1 |
| Bronckaers, A; Foulquier, S; Nelissen, E; Ponsaerts, L; Prickaerts, J; Sandner, P; Schepers, M; Vanmierlo, T | 1 |
| Barratt-Due, A; Espevik, T; Fløisand, Y; Gerogianni, A; Lau, C; McAdam, MB; Mollnes, TE; Nilsson, PH; Thomas, AM | 1 |
| Bennett, LF; Hankey-Giblin, P; Liao, C; Paulson, RF; Prabhu, KS; Quickel, MD; Vijay-Kumar, M; Yeoh, BS | 1 |
| Cespedes, JC; Harbuzariu, A; Harp, KO; Liu, M; Nti, A; Pitts, S; Shaw, AP; Stiles, JK | 1 |
| Ding, J; Gao, H; Pang, DW; Pu, K; Wu, G; Xie, HY; Zhang, C; Zhang, J; Zhao, Q; Zhuang, W | 1 |
| Gueler, F; Immenschuh, S; Pradhan, P; Vijayan, V | 1 |
| Bácsi, A; Balogh, E; Bognár, L; Erdei, J; Fejes, Z; Jeney, V; Kappelmayer, J; Nagy, A; Nagy, B; Novák, L; Nyakundi, BB; Paragh, G; Tóth, A | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; 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Yoshikawa, N; You, Q; Yu, B; Yu, CQ; Yu, H; Yu, HG; Yu, J; Yu, L; Yu, Q; Yu, X; Yu, Y; Yu, YK; Yu, Z; Yuan, Q; Yuan, R; Yuan, W; Yuan, X; Yuan, Y; Zager, RA; Zagozdzon, A; Zaller, N; Zang, YP; Zappi, ME; Zelikoff, JT; Zeman, T; Zhai, X; Zhan, P; Zhang, B; Zhang, C; Zhang, G; Zhang, H; Zhang, HB; Zhang, J; Zhang, JS; Zhang, L; Zhang, M; Zhang, Q; Zhang, RX; Zhang, S; Zhang, T; Zhang, W; Zhang, WH; Zhang, X; Zhang, XX; Zhang, Y; Zhang, YQ; Zhang, YW; Zhang, Z; Zhang, ZH; Zhao, D; Zhao, FL; Zhao, K; Zhao, L; Zhao, M; Zhao, R; Zhao, S; Zhao, W; Zhao, WG; Zhao, X; Zhao, Y; Zheng, G; Zheng, J; Zheng, S; Zheng, W; Zheng, Y; Zheng, YG; Zhong, Z; Zhou, C; Zhou, D; Zhou, H; Zhou, HY; Zhou, L; Zhou, Q; Zhou, X; Zhou, Y; Zhou, YL; Zhou, Z; Zhu, J; Zhu, L; Zhu, N; Zhu, X; Zhu, XF; Zhu, Y; Zhu, Z | 1 |
| Fan, C; Feng, C; Gao, Y; Li, H; Lu, H; Qi, Q; Tang, W; Wu, B; Wu, Y; Zhang, Z; Zuo, J | 1 |
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| Alves-Filho, JC; Barja-Fidalgo, C; Cunha, FQ; Curti, C; Czaikoski, PG; Dal-Secco, D; Freitas, A; Nascimento, DC; Pestana, CR; Sônego, F; Spiller, F; Suavinha, MM; Trevelin, SC | 1 |
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| Arruda, MA; Barja-Fidalgo, C; de Freitas, MS; Graça-Souza, AV; Oliveira, PL | 1 |
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45 review(s) available for heme and Innate Inflammatory Response
| Article | Year |
|---|---|
A Dual Role of Heme Oxygenase-1 in Tuberculosis.
Topics: Bilirubin; Heme; Heme Oxygenase-1; Humans; Inflammation; Iron; Tuberculosis | 2022 |
Temporal brain transcriptome analysis reveals key pathological events after germinal matrix hemorrhage in neonatal rats.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Cerebral Hemorrhage; Gene Expression Profiling; Heme; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Inflammation; Rats; Transcriptome | 2022 |
The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions.
Topics: Anemia, Sickle Cell; Heme; Hemolysis; Humans; Inflammasomes; Inflammation; Interleukin-1beta; NLR Family, Pyrin Domain-Containing 3 Protein | 2023 |
Meconium-stained amniotic fluid.
Topics: Amniotic Fluid; Chorioamnionitis; Female; Heme; Humans; Infant, Newborn; Inflammation; Meconium; Meconium Aspiration Syndrome; Pregnancy; Pregnancy Complications | 2023 |
Basic Mechanisms of Hemolysis-Associated Thrombo-Inflammation and Immune Dysregulation.
Topics: Erythrocytes; Heme; Hemoglobins; Hemolysis; Humans; Inflammation | 2023 |
Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?
Topics: Cognitive Dysfunction; Cyclic GMP; Heme; Humans; Inflammation; Soluble Guanylyl Cyclase; Vascular Diseases | 2023 |
Interplay of Heme with Macrophages in Homeostasis and Inflammation.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; DNA-Binding Proteins; Erythropoiesis; Hematopoiesis; Heme; Hemoglobins; Homeostasis; Humans; Inflammation; Macrophages; Monocytes | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; 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Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Two Faces of Heme Catabolic Pathway in Newborns: A Potential Role of Bilirubin and Carbon Monoxide in Neonatal Inflammatory Diseases.
Topics: Bilirubin; Carbon Monoxide; Heme; Humans; Infant, Newborn; Infant, Newborn, Diseases; Inflammation; Reactive Oxygen Species | 2020 |
TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins.
Topics: Animals; Heme; Heme-Binding Proteins; Humans; Inflammation; Lipid Metabolism; Membrane Microdomains; Protein Binding; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4 | 2020 |
The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease.
Topics: Anemia, Sickle Cell; Animals; Cardiovascular Diseases; Disease Progression; Heme; Heme Oxygenase-1; Hemolysis; Hemopexin; Humans; Hypertension, Pulmonary; Inflammation; Interleukin-6; Oxidative Stress; Placenta Growth Factor; Respiratory Hypersensitivity | 2020 |
Significance of Heme and Heme Degradation in the Pathogenesis of Acute Lung and Inflammatory Disorders.
Topics: Animals; Heme; Heme Oxygenase-1; Humans; Inflammation; Pneumonia; Sepsis; Systemic Inflammatory Response Syndrome | 2021 |
Heme-mediated cell activation: the inflammatory puzzle of sickle cell anemia.
Topics: Anemia, Sickle Cell; Cell Movement; Endothelial Cells; Heme; Hemoglobins; Hemolysis; Humans; Inflammation; Iron; Leukocytes; Vascular Diseases | 2017 |
Heme and hemolysis in innate immunity: adding insult to injury.
Topics: Animals; Heme; Hemolysis; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Macrophages | 2018 |
The macrophage heme-heme oxygenase-1 system and its role in inflammation.
Topics: Animals; Heme; Heme Oxygenase-1; Humans; Inflammation; Inflammation Mediators; Lipid Peroxidation; Macrophages | 2018 |
Misdistribution of iron and oxidative stress in chronic kidney disease.
Topics: Aminolevulinic Acid; Anemia; Hematinics; Heme; Hepcidins; Humans; Inflammation; Iron; Iron Overload; Leptin; Mitochondria; Oxidative Stress; Renal Insufficiency, Chronic | 2019 |
Pigment Nephropathy: Novel Insights into Inflammasome-Mediated Pathogenesis.
Topics: Animals; Diabetic Nephropathies; Heme; Hemoglobins; Humans; Inflammasomes; Inflammation; Kidney; Kidney Diseases; Models, Molecular; Myoglobin; NLR Family, Pyrin Domain-Containing 3 Protein | 2019 |
Markers of oxidant stress that are clinically relevant in aging and age-related disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Age Factors; Aging; Animals; Biomarkers; Deoxyguanosine; DNA Breaks, Double-Stranded; Erythrocytes; Free Radicals; Glutathione; Guanine; Heme; Humans; Inflammation; Isoprostanes; Lipid Peroxidation; Oxidants; Oxidative Stress; Reactive Oxygen Species | 2013 |
Red meat, dietary heme iron, and risk of type 2 diabetes: the involvement of advanced lipoxidation endproducts.
Topics: Animals; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Female; Ferritins; Food Handling; Glycation End Products, Advanced; Heme; Humans; Inflammation; Insulin Resistance; Iron, Dietary; Lipid Peroxidation; Male; Meat; Nitrates; Nitrites; Risk Factors | 2013 |
Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases.
Topics: Animals; Atherosclerosis; Autoimmune Diseases; Enzyme Activation; Heme; Heme Oxygenase-1; Hemopexin; Humans; Inflammation; Oxidative Stress | 2015 |
5-Aminolevulinic acid regulates the inflammatory response and alloimmune reaction.
Topics: Aminolevulinic Acid; Heme; Heme Oxygenase-1; Histocompatibility; Humans; Immunity; Immunologic Factors; Inflammation; Macrophages; Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Signal Transduction; Transplantation, Homologous | 2016 |
Oxidative Stress in Intracerebral Hemorrhage: Sources, Mechanisms, and Therapeutic Targets.
Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Heme; Hemoglobins; Humans; Inflammation; Iron; Mice; Mitochondria; NADPH Oxidases; NF-E2-Related Factor 2; Nitric Oxide Synthase; Oxidative Stress; Oxygen; Prognosis; Signal Transduction; Stroke; Superoxide Dismutase | 2016 |
Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cardiovascular Agents; Cardiovascular Diseases; Child; Diabetes Complications; Endothelium, Vascular; Enzyme Induction; Female; Genetic Therapy; Heme; Heme Oxygenase-1; Humans; Inflammation; Iron; Male; Mice; Mice, Knockout; Neovascularization, Physiologic; Rabbits; Rats; Vasomotor System | 2008 |
[Anemia and iron metabolism].
Topics: Anemia; Anemia, Hypochromic; Cation Transport Proteins; Erythrocytes; Gene Expression Regulation; Heme; Hemoglobins; Humans; Inflammation; Iron; Iron-Regulatory Proteins | 2008 |
Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging.
Topics: Animals; Antigens, Neoplasm; Free Radical Scavengers; Haptoglobins; Heme; Hemoglobins; Hemolysis; Humans; Inflammation; Models, Biological; Receptors, Cell Surface; Trypanosoma | 2009 |
Cardiovascular consequences when nitric oxide and lipid signaling converge.
Topics: Cell Proliferation; Eicosanoids; Fatty Acids; Guanylate Cyclase; Heme; Inflammation; Inflammation Mediators; Iron; Nitric Oxide; Oxidation-Reduction; Paracrine Communication; Signal Transduction; Thrombosis; Tunica Intima; Vasodilation | 2009 |
Mechanisms of cell protection by heme oxygenase-1.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cytoprotection; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase-1; Humans; Inflammation; Tumor Necrosis Factor-alpha | 2010 |
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential.
Topics: Animals; Anti-Inflammatory Agents; Bilirubin; Carbon Monoxide; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Heme; Heme Oxygenase-1; Humans; Immunomodulation; Inflammation; Isoenzymes; Myeloid Cells; Oxidation-Reduction; Signal Transduction | 2010 |
The heme-heme oxygenase system in wound healing; implications for scar formation.
Topics: Animals; Apoptosis; Cicatrix; Cicatrix, Hypertrophic; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemeproteins; Humans; Inflammation; Myofibroblasts; Neovascularization, Physiologic; Oxidative Stress; Skin; Ultraviolet Rays; Wound Healing | 2010 |
Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.
Topics: Adhesins, Bacterial; Animals; Antimicrobial Cationic Peptides; Bacterial Adhesion; Chronic Periodontitis; Complement Activation; Cysteine Endopeptidases; Gingipain Cysteine Endopeptidases; Gingiva; Heme; Humans; Immune Evasion; Immunity, Innate; Inflammation; Porphyromonas gingivalis; Protein Denaturation; Receptors, Proteinase-Activated; Signal Transduction; Substrate Specificity; Virulence Factors | 2010 |
Protective role of heme oxygenase-1 against inflammation in atherosclerosis.
Topics: Animals; Atherosclerosis; Cytokines; Heme; Heme Oxygenase-1; Humans; Inflammation; Inflammation Mediators; Mice; Mice, Knockout; Models, Biological | 2011 |
A new role for myeloid HO-1 in the innate to adaptive crosstalk and immune homeostasis.
Topics: Adaptive Immunity; Animals; DEAD Box Protein 58; DEAD-box RNA Helicases; Gene Expression; Heme; Heme Oxygenase-1; Homeostasis; Humans; Immunity, Innate; Inflammation; Interferon Regulatory Factor-3; Interferon Type I; Mice; Mice, Knockout; Myeloid Cells; Phosphorylation; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 4; Transcriptional Activation | 2011 |
Therapeutic potential of carbon monoxide in multiple sclerosis.
Topics: Animals; Anti-Inflammatory Agents; Autoimmunity; Boranes; Carbon Monoxide; Carbonates; Cardiotonic Agents; Cytokines; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Inflammation; Multiple Sclerosis; Neuroimmunomodulation; Organometallic Compounds; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasodilator Agents | 2012 |
[Iron metabolism: State of the art].
Topics: Anemia, Iron-Deficiency; Antimicrobial Cationic Peptides; Erythropoiesis; Heme; Hemochromatosis; Hemoglobins; Hepcidins; Homeostasis; Humans; Inflammation; Intestinal Absorption; Iron; Renal Insufficiency; Signal Transduction | 2013 |
Different faces of the heme-heme oxygenase system in inflammation.
Topics: Animals; Apoptosis; Cell Adhesion Molecules; Cell Differentiation; Cell Division; Cytoprotection; Erythrocytes; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Humans; Inflammation; Oxidative Stress | 2003 |
[Erythrophagocytosis and recycling of heme iron in normal and pathological conditions; regulation by hepcidin].
Topics: Anemia; Antimicrobial Cationic Peptides; Cation Transport Proteins; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Ferritins; Heme; Hemochromatosis; Hepatocytes; Hepcidins; Humans; Inflammation; Intestinal Absorption; Iron; Macrophages; Models, Biological; Phagocytosis; Thalassemia | 2005 |
Heme oxygenase-1 expression in disease states.
Topics: Animals; Heme; Heme Oxygenase-1; Humans; Inflammation; Reperfusion Injury | 2005 |
Heme and innate immunity: new insights for an old molecule.
Topics: Acute Disease; Chronic Disease; Heme; Hemolysis; Humans; Immunity, Innate; Inflammation | 2005 |
Heme oxygenase-1 and cardiovascular disease.
Topics: Animals; Atherosclerosis; Bilirubin; Cadmium Chloride; Carbon Monoxide; Cardiovascular Diseases; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Heme; Heme Oxygenase-1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Oxidative Stress; Protein Isoforms | 2006 |
Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility.
Topics: Animals; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Gastrointestinal Motility; Heme; Heme Oxygenase (Decyclizing); Humans; Inactivation, Metabolic; Inflammation; Intestinal Absorption; Intestinal Mucosa; Iron | 2006 |
Nitric oxide-independent stimulation of soluble guanylate cyclase with BAY 41-2272 in cardiovascular disease.
Topics: Animals; Antihypertensive Agents; Benzoates; Cardiovascular Diseases; Cell Adhesion; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Heart Failure; Heme; Humans; Hypertension; Hypertension, Pulmonary; Inflammation; Leukocytes; Nitric Oxide; Platelet Aggregation; Pyrazoles; Pyridines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilator Agents | 2007 |
Heme oxygenase-1: a fundamental guardian against oxidative tissue injuries in acute inflammation.
Topics: Acute Disease; Animals; Heme; Heme Oxygenase-1; Humans; Inflammation; Oxidative Stress | 2007 |
[Possibility of heme oxygenase-1 as a target for therapy against allergic inflammation].
Topics: Animals; Antigen-Antibody Reactions; Cytokines; Heme; Heme Oxygenase-1; Humans; Hypersensitivity; Inflammation; Mast Cells; Oxidative Stress; Transcription Factor AP-1; Transfection | 2007 |
Mammalian heme peroxidases: from molecular mechanisms to health implications.
Topics: Animals; Eosinophil Peroxidase; Heme; Humans; Inflammation; Lactoperoxidase; Oxidants; Peroxidase; Peroxidases | 2008 |
Heme-induced cell adhesion in the pathogenesis of sickle-cell disease and inflammation.
Topics: Anemia, Sickle Cell; Cell Adhesion; Heme; Humans; Inflammation | 2001 |
2 trial(s) available for heme and Innate Inflammatory Response
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; 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Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Effect of dietary meat and fish on endogenous nitrosation, inflammation and genotoxicity of faecal water.
Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers; Diet; DNA Breaks; Feces; Feeding Behavior; Female; Fishes; Heme; Humans; Inflammation; Male; Meat; Middle Aged; Mutagens; Nitrosation; Nitroso Compounds; Water; Young Adult | 2010 |
101 other study(ies) available for heme and Innate Inflammatory Response
| Article | Year |
|---|---|
Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation.
Topics: Animals; Colitis; Heme; Heme Oxygenase-1; Inflammation; Macrophages; Mice; Monocytes | 2022 |
Protective activity of purpurin against d-galactosamine and lipopolysaccharide-induced hepatorenal injury by upregulation of heme oxygenase-1 in the RBC degradation cycle.
Topics: Animals; Anthraquinones; Antioxidants; Biliverdine; Catalase; Cholesterol; Cytochrome P-450 CYP2E1; Female; Ferritins; Food Additives; Galactosamine; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Heme; Heme Oxygenase-1; Hemosiderin; Inflammation; Lipopolysaccharides; Liver; NADP; Rats; Superoxide Dismutase; Transferases; Triglycerides; Up-Regulation | 2022 |
MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Antibodies, Monoclonal; Complement Activation; Disease Models, Animal; E-Selectin; Heme; Hemoglobins; Hemolysis; Hypoxia; Inflammation; Intercellular Adhesion Molecule-1; Mannose-Binding Lectins; Mannose-Binding Protein-Associated Serine Proteases; Mice; NF-kappa B; Vascular Cell Adhesion Molecule-1; Volatile Organic Compounds | 2022 |
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury.
Topics: Animals; Disease Models, Animal; Heme; Hemolysis; Inflammation; Mice; Mice, Knockout; NF-kappa B; Phenylhydrazines; Sulfonamides; Toll-Like Receptor 4 | 2022 |
The effect of 5-aminolevulinic acid on canine peripheral blood mononuclear cells.
Topics: Aminolevulinic Acid; Animals; Dog Diseases; Dogs; Heme; Humans; Inflammation; Leukocytes, Mononuclear; Signal Transduction | 2022 |
HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Cytokines; Heme; Humans; Inflammation; Mice; Monocytes; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Effect of hemoglobin on Nile tilapia (Oreochromis niloticus) kidney (NTK) cell line damage.
Topics: Animal Feed; Animals; Antioxidants; Cell Line; Cichlids; Heme; Hemoglobins; Inflammation; Iron; Kidney; Oxidative Stress; Reactive Oxygen Species | 2022 |
Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Heme; Hemolysis; Humans; Inflammation; Ischemia; Mice; Mice, Transgenic; Neuregulin-1 | 2023 |
Hemoglobin induces inflammation through NF-kB signaling pathway and causes cell oxidative damage in grass carp (
Topics: Animals; Carps; Heme; Hemoglobins; Hemolysis; Inflammation; NF-kappa B; Oxidative Stress; Signal Transduction | 2022 |
MiR-451a and let-7i-5p loaded extracellular vesicles attenuate heme-induced inflammation in hiPSC-derived endothelial cells.
Topics: Cytokines; Endothelial Cells; Extracellular Vesicles; Heme; Hemolysis; Humans; Induced Pluripotent Stem Cells; Inflammation; Malaria; MicroRNAs; Plasmodium | 2022 |
Dental Pulp Inflammation Initiates the Occurrence of Mast Cells Expressing the α
Topics: Cyclic GMP; Dental Pulp; Guanylate Cyclase; Heme; Humans; Inflammation; Nitric Oxide; Soluble Guanylyl Cyclase | 2023 |
Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease.
Topics: Anemia, Sickle Cell; Heme; Humans; Inflammation; Interleukin-4; Macrophages; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Toll-Like Receptor 4 | 2023 |
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs.
Topics: Animals; Heme; Inflammasomes; Inflammation; Intracellular Signaling Peptides and Proteins; Mice; Pathogen-Associated Molecular Pattern Molecules; Pyroptosis | 2023 |
Histidine-rich protein II nanoparticle delivery of heme iron load drives endothelial inflammation in cerebral malaria.
Topics: Animals; Endothelial Cells; Heme; Hemeproteins; Histidine; Inflammation; Iron; Malaria, Cerebral; Malaria, Falciparum; Mice | 2023 |
Free heme exacerbates colonic injury induced by anti-cancer therapy.
Topics: Animals; Colon; Doxorubicin; Heme; Hemolysis; Hemopexin; Humans; Inflammation; Mice; Mice, Knockout | 2023 |
NLRP12 drives PANoptosis in response to heme.
Topics: Heme; Humans; Inflammation; Intracellular Signaling Peptides and Proteins | 2023 |
NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation.
Topics: Cell Death; Heme; Hemolysis; Humans; Immunity, Innate; Inflammation; Intracellular Signaling Peptides and Proteins; Necrosis; Pathogen-Associated Molecular Pattern Molecules | 2023 |
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood.
Topics: Adult; Anemia, Sickle Cell; Animals; Blood Coagulation; Complement Activation; Complement C5; Cytokines; Granulocytes; Heme; Hemolysis; Humans; Inflammation; Lipopolysaccharide Receptors; Male; Monocytes; Swine; Thromboplastin | 2019 |
Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C.
Topics: Animals; Bone Morphogenetic Protein 4; DNA-Binding Proteins; Erythrocytes; Erythroid Precursor Cells; Erythropoiesis; Growth Differentiation Factor 15; Heme; Inflammation; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Phagocytosis; Signal Transduction; Spleen; Stress, Physiological | 2019 |
Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids.
Topics: Apoptosis; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Chemokine CXCL12; Heme; Humans; Induced Pluripotent Stem Cells; Inflammation; Malaria, Cerebral; Models, Biological; Neuregulin-1; Organoids; Receptor, ErbB-4; Receptors, CXCR3; Umbilical Cord | 2019 |
Molecularly Engineered Macrophage-Derived Exosomes with Inflammation Tropism and Intrinsic Heme Biosynthesis for Atherosclerosis Treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Exosomes; Heme; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Tropism | 2020 |
The Role of Hemoglobin Oxidation Products in Triggering Inflammatory Response Upon Intraventricular Hemorrhage in Premature Infants.
Topics: Brain; Cerebral Intraventricular Hemorrhage; Endothelial Cells; Erythrocytes; Female; Heme; Hemoglobins; Humans; Infant, Newborn; Infant, Premature; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-8; Male; Neurogenic Inflammation; Oxidation-Reduction; Premature Birth; Vascular Cell Adhesion Molecule-1 | 2020 |
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Dextran Sulfate; Female; Heme; Heme Oxygenase-1; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Interferon Regulatory Factors; Intestinal Mucosa; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Transcription Factor RelA | 2020 |
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages.
Topics: Animals; Biological Transport; DNA-Binding Proteins; Down-Regulation; Female; Heme; Inflammation; Interferon-gamma; Iron; Ligands; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; Monocytes; NF-kappa B; Signal Transduction; STAT Transcription Factors; Toll-Like Receptors | 2020 |
Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.
Topics: Animals; Disease Models, Animal; Female; Heme; Hemolysis; Humans; In Vitro Techniques; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Phagocytes; Phagocytosis; Phenotype; RNA-Seq; Single-Cell Analysis; Spherocytosis, Hereditary | 2020 |
Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice.
Topics: Abortion, Induced; Alarmins; Animals; Blood Vessels; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Fetal Resorption; Gene Expression; Heme; Heme Oxygenase-1; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Membrane Proteins; Mice; Placenta; Pregnancy | 2020 |
Heat-Killed
Topics: Alveolar Epithelial Cells; Caspase 1; Caspase 3; Fusobacterium nucleatum; Heme; Hot Temperature; Humans; Hydrogen Peroxide; Inflammation; Interleukin-6; Interleukin-8 | 2020 |
Inflammation in the Human Periodontium Induces Downregulation of the α
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cyclic GMP; Gene Expression Regulation; Heme; Humans; Inflammation; Iron; Nitric Oxide; Osteoclasts; Oxidation-Reduction; Periodontal Ligament; Periodontium; Soluble Guanylyl Cyclase | 2021 |
Vasculo-toxic and pro-inflammatory action of unbound haemoglobin, haem and iron in transfusion-dependent patients with haemolytic anaemias.
Topics: Adolescent; Adult; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Child; Child, Preschool; Endothelium, Vascular; Female; Heme; Hemoglobins; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Iron; Male; Spherocytosis, Hereditary; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2021 |
Noncanonical Roles of Caspase-4 and Caspase-5 in Heme-Driven IL-1β Release and Cell Death.
Topics: Alarmins; Anemia, Sickle Cell; Caspases; Caspases, Initiator; Cell Death; Cells, Cultured; Erythrocytes; Heme; Hemolysis; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Up-Regulation | 2021 |
Intracerebral Injection of Heme Induces Lipid Peroxidation, Neuroinflammation, and Sensorimotor Deficits.
Topics: Animals; Behavior, Animal; Corpus Striatum; Heme; Inflammasomes; Inflammation; Lipid Peroxidation; Mice; Neuroinflammatory Diseases; NLR Family, Pyrin Domain-Containing 3 Protein | 2021 |
Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells.
Topics: Anemia, Sickle Cell; Animals; Endothelial Cells; Heme; Hemopexin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Interleukin-8; Lymphocyte Antigen 96; Mice; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Linking COVID-19 and Heme-Driven Pathophysiologies: A Combined Computational-Experimental Approach.
Topics: Angiotensin-Converting Enzyme 2; Computational Biology; COVID-19; Heme; Hemolysis; Host-Pathogen Interactions; Humans; Inflammation; Models, Biological; Models, Molecular; Protein Binding; Protein Interaction Maps; SARS-CoV-2; Serine Endopeptidases; Viral Proteins | 2021 |
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo.
Topics: Animals; Colorectal Neoplasms; Diet; Heme; Inflammation; Intestinal Mucosa; Iron; Mice; RNA, Ribosomal, 16S | 2021 |
Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells.
Topics: Cell Line, Tumor; Cell Survival; Chlorpyrifos; Down-Regulation; Flavanones; Heme; Heme Oxygenase-1; Humans; Inflammation; Mitochondria; NF-E2-Related Factor 2 | 2021 |
Characteristics of the heme catabolic pathway in mild unconjugated hyperbilirubinemia and their associations with inflammation and disease prevention.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Bilirubin; Biomarkers; Cytokines; Female; Gene Expression; Genotype; Heme; Heme Oxygenase-1; Humans; Hyperbilirubinemia; Inflammation; Inflammation Mediators; Male; Metabolic Networks and Pathways; Microsatellite Repeats; Middle Aged; Severity of Illness Index; Sex Factors; Young Adult | 2017 |
Heme molecule functions as an endogenous agonist of astrocyte TLR2 to contribute to secondary brain damage after intracerebral hemorrhage.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Injuries; Cerebral Hemorrhage; Heme; Inflammation; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Toll-Like Receptor 2 | 2017 |
Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.
Topics: Anemia; Anemia, Sickle Cell; Animals; Antioxidants; Dimethyl Fumarate; Disease Models, Animal; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Heme; Humans; Inflammation; Leukemia, Erythroblastic, Acute; Mice; NF-E2-Related Factor 2; RNA, Messenger; Spleen | 2017 |
Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model.
Topics: Adsorption; Animals; Cytokines; Gene Expression Regulation; Hematocrit; Heme; Hemodynamics; Hemoglobins; Inflammation; Kidney; Kidney Function Tests; Leukocyte Count; Models, Animal; Perfusion; Platelet Count; Regional Blood Flow; Sus scrofa | 2017 |
Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cells, Cultured; Disease Models, Animal; E-Selectin; Erythrocytes; Female; Heme; Hemolysis; Hepatitis A Virus Cellular Receptor 1; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Ki-67 Antigen; Kidney; Lipocalin-2; Mice; Mice, Inbred C57BL; Phenylhydrazines; Vascular Diseases | 2018 |
Revisiting the putative role of heme as a trigger of inflammation.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Profiling; Heme; Heme Oxygenase-1; Hemolysis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Activation; Neutrophils; Transcriptome | 2018 |
Hemoglobin metabolism by-products are associated with an inflammatory response in patients with hemorrhagic stroke.
Topics: Aged; Brain; Cerebral Hemorrhage; Cohort Studies; Female; Heme; Hemoglobins; Hemopexin; Humans; Inflammation; Male; Middle Aged; Prospective Studies; Stroke; Subarachnoid Hemorrhage | 2018 |
Heme and hemoglobin suppress amyloid β-mediated inflammatory activation of mouse astrocytes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Cells, Cultured; Cytokines; Heme; Hemoglobins; Immune Tolerance; Inflammation; Mice; Neuroimmunomodulation; Peptide Fragments; Phagocytosis; RAW 264.7 Cells | 2018 |
Relationship between Anaemia, Haemolysis, Inflammation and Haem Oxygenase-1 at Admission with Sepsis: a pilot study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Female; Haptoglobins; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Hemolysis; Hemopexin; Humans; Inflammation; Interleukin-10; Leukocyte Count; Male; Middle Aged; Pilot Projects; Sepsis; Young Adult | 2018 |
Oxidized hemoglobin forms contribute to NLRP3 inflammasome-driven IL-1β production upon intravascular hemolysis.
Topics: Animals; Caspase 1; Enzyme Activation; Female; Heme; Hemoglobins; Hemolysis; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Male; Methemoglobin; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidation-Reduction; Peritonitis; RAW 264.7 Cells; Reactive Oxygen Species | 2019 |
Hemin impairs resolution of inflammation via microRNA-144-3p-dependent downregulation of ALX/FPR2.
Topics: 3' Untranslated Regions; Animals; Blotting, Western; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Flow Cytometry; Heme; Hemin; HL-60 Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Neutrophils; Real-Time Polymerase Chain Reaction; Signal Transduction | 2019 |
TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Cells, Cultured; Gene Expression Regulation; Heme; Heme Oxygenase-1; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Signal Transduction; Sulfonamides; Toll-Like Receptor 4 | 2019 |
Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation.
Topics: Aldehydes; Animals; Colon; Heme; Homeostasis; Inflammation; Intestinal Mucosa; Iron; Lipid Peroxides; Male; Microbiota; Mutagenicity Tests; Rats; Rats, Inbred F344 | 2019 |
Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme.
Topics: Anti-Inflammatory Agents; Autoimmune Diseases; Cell Line; Complement System Proteins; Endothelial Cells; Heme; Human Umbilical Vein Endothelial Cells; Humans; Immunoglobulins, Intravenous; Inflammation | 2019 |
S100A8 acts as an autocrine priming signal for heme-induced human Mϕ pro-inflammatory responses in hemolytic inflammation.
Topics: Adult; Animals; Calgranulin A; Female; Heme; Hemolysis; Humans; Inflammation; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; NF-kappa B; Toll-Like Receptor 4 | 2019 |
Myeloperoxidase acts as a source of free iron during steady-state catalysis by a feedback inhibitory pathway.
Topics: Catalysis; Chlorides; Feedback, Physiological; Ferrozine; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Iron; Kinetics; Metabolic Networks and Pathways; Oxidation-Reduction; Peroxidase | 2013 |
Proinflammatory responses of heme in alveolar macrophages: repercussion in lung hemorrhagic episodes.
Topics: Animals; Heme; Humans; Inflammation; Macrophages, Alveolar; Metabolic Syndrome; Mice; Pneumonia; Rats | 2013 |
Effect of iron liposomes on anemia of inflammation.
Topics: Administration, Oral; Anemia, Iron-Deficiency; Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Ferric Compounds; Hematinics; Heme; Hepcidins; Inflammation; Intestinal Absorption; Iron; Liposomes; Male; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical; Time Factors; Ultrasonics | 2013 |
Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.
Topics: Animals; Antioxidants; Bilirubin; Cell Line; Cell Survival; Gene Expression Regulation; Heme; Heme Oxygenase-1; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Microglia; NF-E2-Related Factor 2; Small Molecule Libraries | 2013 |
Administration of heme arginate ameliorates murine type 2 diabetes independently of heme oxygenase activity.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adiponectin; Adipose Tissue; Adiposity; Animals; Arginine; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heme; Heme Oxygenase (Decyclizing); Hyperglycemia; Inflammation; Insulin-Secreting Cells; Metalloporphyrins; Mice; Pilot Projects | 2013 |
Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Bone Marrow Cells; Cell Adhesion; Endothelial Cells; Haptoglobins; Heme; Hemoglobins; Hemolysis; Hemopexin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B p50 Subunit; Oxidative Stress; Phenotype; Signal Transduction; Toll-Like Receptor 4; Vasoconstriction; von Willebrand Factor | 2014 |
Heme induces IL-1β secretion through activating NLRP3 in kidney inflammation.
Topics: Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Heme; Inflammasomes; Inflammation; Interleukin-1beta; Kidney; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Purinergic P2X; Ureteral Obstruction | 2014 |
Influence of protein intake from haem and non-haem animals and plant origin on inflammatory biomarkers among apparently-healthy adults in Greece.
Topics: Adult; Animals; Biomarkers; C-Reactive Protein; Creatinine; Cystatin C; Diet; Diet Records; Dietary Proteins; Feeding Behavior; Female; Ferritins; Greece; Haptoglobins; Hematocrit; Heme; Hemoglobins; Humans; Inflammation; Iron; Lipids; Male; Middle Aged; Nutritional Status; Plant Proteins, Dietary; Reference Values; Surveys and Questionnaires; Uric Acid | 2013 |
Human mesenchymal stromal cells suppress T-cell proliferation independent of heme oxygenase-1.
Topics: Adolescent; Adult; Cell Proliferation; Cell- and Tissue-Based Therapy; Cells, Cultured; Female; Heme; Heme Oxygenase-1; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Lymphocyte Activation; Male; Mesenchymal Stem Cells; Metalloporphyrins; Protoporphyrins; T-Lymphocytes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Inactivation of myeloperoxidase by benzoic acid hydrazide.
Topics: Amino Acid Sequence; Aniline Compounds; Animals; Benzoic Acid; Carbocyanines; Catalytic Domain; Cattle; Electrons; Enzyme Inhibitors; Fluorescent Dyes; Free Radicals; Glutamic Acid; Heme; Humans; Hydrogen Peroxide; Inflammation; Lysine; Mass Spectrometry; Methionine; Molecular Conformation; Molecular Sequence Data; Neutrophils; Oxygen; Peroxidase; Spectrometry, Fluorescence | 2015 |
The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice.
Topics: Anemia, Sickle Cell; Animals; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Endothelium; Erythrocytes; Female; Fucose; Heme; Hemoglobins; Humans; Inflammation; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Neutrophils; NF-kappa B; Vascular Cell Adhesion Molecule-1; Venules | 2015 |
Peroxidase Enzymes Regulate Collagen Biosynthesis and Matrix Mineralization by Cultured Human Osteoblasts.
Topics: Arthroplasty, Replacement, Hip; Ascorbic Acid; Bone and Bones; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Eosinophil Peroxidase; Extracellular Matrix; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Heme; Humans; Inflammation; Osteoblasts; Peroxidases; Protein Processing, Post-Translational; Recombinant Proteins | 2016 |
High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbβ Leads to Its Degradation and Indirectly Regulates Its Interaction with Nuclear Receptor Corepressor.
Topics: Amino Acid Motifs; Apoproteins; Circadian Rhythm; Cycloheximide; Gene Expression Regulation; HEK293 Cells; Heme; Humans; Inflammation; Ions; Ligands; Mass Spectrometry; Metals; Myoglobin; Nuclear Receptor Co-Repressor 1; Promoter Regions, Genetic; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Transfection; Ubiquitin | 2016 |
TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages.
Topics: Animals; Apoferritins; Biological Transport; Cell Line; Cells, Cultured; Gene Expression Regulation; Heme; Heme Oxygenase-1; Humans; Inflammation; Iron; Lipopolysaccharides; Macrophages; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Reactive Oxygen Species; Receptors, Virus; Toll-Like Receptor 4; Toll-Like Receptors; Transcription Factors | 2016 |
Heme-Exposed Pooled Therapeutic IgG Improves Endotoxemia Survival.
Topics: Animals; Anti-Inflammatory Agents; Antibody Specificity; Endotoxemia; Heme; Humans; Immunoglobulin G; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Sepsis; Survival Rate | 2017 |
Sickle cell trait is associated with controlled levels of haem and mild proinflammatory response during acute malaria infection.
Topics: Child, Preschool; Convalescence; Cytokines; Female; Genotype; Heme; Heme Oxygenase-1; Hemoglobins; Humans; Infant; Inflammation; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Sickle Cell Trait | 2017 |
Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein.
Topics: Adult; Aged; Animals; Apolipoprotein A-I; Biomarkers; Coronary Disease; Female; Haptoglobins; Heme; Hemoglobins; Humans; Hyperlipidemias; Inflammation; Interleukin-10; Interleukin-6; Lipid A; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Middle Aged; Reactive Oxygen Species; Young Adult | 2009 |
Heme impairs prostaglandin E2 and TGF-beta production by human mononuclear cells via Cu/Zn superoxide dismutase: insight into the pathogenesis of severe malaria.
Topics: Adolescent; Adult; Cells, Cultured; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Flow Cytometry; Heme; Hemolysis; Humans; Inflammation; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; RNA Interference; Superoxide Dismutase; Transforming Growth Factor beta; Young Adult | 2010 |
Synergistic inflammation is induced by blood degradation products with microbial Toll-like receptor agonists and is blocked by hemopexin.
Topics: Animals; Bacterial Toxins; Blood; Cells, Cultured; Cytokines; Escherichia coli; Heme; Hemoglobins; Hemopexin; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Staphylococcus aureus; Toll-Like Receptors | 2010 |
Dietary heme adversely affects experimental colitis in rats, despite heat-shock protein induction.
Topics: Animals; Biomarkers; Colitis; Colon; Enterobacter; Heat-Shock Proteins; Heme; Heme Oxygenase-1; Inflammation; Interleukin-1beta; Intestinal Mucosa; Lactobacillaceae; Male; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2011 |
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution.
Topics: Anemia; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cells, Cultured; Erythrocytes; Heme; Heme Oxygenase-1; Humans; Inflammation; Iron; Kidney; Liver; Macrophages; Mice; Mice, Knockout; Phagocytosis; Receptors, Cell Surface; Spleen; Tissue Distribution | 2010 |
Roles of SIRT1 in the acute and restorative phases following induction of inflammation.
Topics: Adolescent; Adult; Animals; Female; Ferrochelatase; Heme; Humans; Inflammation; Male; Metals; Mice; Mutation; Porphyrins; Sirtuin 1; Tetrapyrroles | 2010 |
Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis.
Topics: Animals; Bilirubin; Cecum; Heme; Heme Oxygenase (Decyclizing); Hemin; Inflammation; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neutrophil Infiltration; Neutrophils; Protoporphyrins; Receptors, Interleukin-8B; Sepsis | 2011 |
Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases.
Topics: Animals; Biocatalysis; Cattle; Chromatography, High Pressure Liquid; Fluorescence; Heme; Hypochlorous Acid; Inflammation; Iron; Kinetics; Lactoperoxidase; Models, Biological; Organ Specificity; Protein Structure, Quaternary; Spectrum Analysis; Thiocyanates | 2011 |
Diet-induced obesity leads to decreased hepatic iron storage in mice.
Topics: Adiponectin; Anemia, Iron-Deficiency; Animals; Antimicrobial Cationic Peptides; Diet; Dietary Fats; Heme; Hepcidins; Inflammation; Iron; Leptin; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; RNA, Messenger; Serum Amyloid A Protein | 2011 |
Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Animals, Newborn; Antibodies, Monoclonal; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Heme; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myeloid Differentiation Factor 88; Neurologic Examination; NF-kappa B; RNA, Messenger; Signal Transduction; Statistics, Nonparametric; Time Factors; Toll-Like Receptor 4; Up-Regulation | 2012 |
Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Erythrocytes; Heme; Heme Oxygenase-1; Hemin; Hemolysis; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Macrophages; Male; Mice; Microglia; Neurons; Rats; Rats, Wistar; Signal Transduction; Subarachnoid Hemorrhage | 2012 |
Oxidative stress and modification of renal vascular permeability are associated with acute kidney injury during P. berghei ANKA infection.
Topics: Acute Kidney Injury; Animals; Apoptosis; Capillary Permeability; Cell Adhesion; Cell Hypoxia; Endothelial Cells; Erythrocytes; Heme; Inflammation; Kidney; Malaria; Mice; Mice, Inbred BALB C; Oxidative Stress; Plasmodium berghei; Reactive Oxygen Species | 2012 |
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states.
Topics: Amyloid beta-Protein Precursor; Apoproteins; Brain; Brain Injuries; Cell Line, Tumor; Cerebral Hemorrhage; Endocytosis; Enzyme Induction; Heme; Heme Oxygenase-1; Hemopexin; Humans; Inflammation; Neurons; Peroxides; Reactive Oxygen Species | 2013 |
Iron supplementation increases disease activity and vitamin E ameliorates the effect in rats with dextran sulfate sodium-induced colitis.
Topics: Administration, Oral; Animals; Antioxidants; Colitis; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Drug Interactions; Feces; Gastrointestinal Hemorrhage; Glutathione Peroxidase; Heme; Inflammation; Iron, Dietary; Lipid Peroxidation; Male; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Vitamin E | 2002 |
How hemolysis causes acute pancreatitis.
Topics: Acute Disease; Animals; Cytokines; Heme; Hemolysis; Humans; Inflammation; Pancreatitis; Rats | 2002 |
The heme-heme oxygenase system: a molecular switch in wound healing.
Topics: Animals; Chemotaxis, Leukocyte; Enzyme Induction; Fibroblasts; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Inflammation; Intercellular Adhesion Molecule-1; Intestines; Isoenzymes; Leukocytes; Membrane Proteins; Mouth Mucosa; Rats; Rats, Wistar; Skin; Wound Healing | 2003 |
Meconium is a source of pro-inflammatory substances and can induce cytokine production in cultured A549 epithelial cells.
Topics: Adult; Cells, Cultured; Cytokines; Epithelial Cells; Female; Heme; Humans; Infant, Newborn; Inflammation; Interleukin-8; Meconium; Pregnancy; Respiratory Mucosa | 2003 |
Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis.
Topics: Blotting, Northern; Blotting, Western; Cyclooxygenase 2; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Heme; Humans; Hypoxia; Inflammation; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Oxygen; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Thromboxane A2; Time Factors; Transfection; Tumor Necrosis Factor-alpha; U937 Cells; Zinc | 2003 |
Bilirubin from heme oxygenase-1 attenuates vascular endothelial activation and dysfunction.
Topics: Animals; Aorta; Aorta, Thoracic; Arginine; Bilirubin; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Gene Expression Profiling; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; In Vitro Techniques; Inflammation; Lipoproteins, LDL; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oligonucleotide Array Sequence Analysis; Tumor Necrosis Factor-alpha; Vasodilation | 2005 |
Identification of the receptor scavenging hemopexin-heme complexes.
Topics: alpha-Macroglobulins; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Chlorocebus aethiops; COS Cells; Electrophoresis, Polyacrylamide Gel; Endocytosis; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Hemopexin; Hemorrhage; Humans; Inflammation; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Microscopy, Confocal; Models, Biological; Monocytes; Oxygen; Protein Binding; Receptors, Cell Surface; RNA, Messenger; Time Factors | 2005 |
Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in inflammation and growth.
Topics: Cell Cycle; Cells, Cultured; Chemokine CCL2; Down-Regulation; Endothelial Cells; Gene Expression Regulation, Enzymologic; Glucose; Heme; Heme Oxygenase-1; Humans; Inflammation; Up-Regulation | 2005 |
Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; Cells, Cultured; Cytoprotection; Endocytosis; Endosomes; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glutathione; Heme; Heme Oxygenase-1; Hemoglobins; Humans; Inflammation; Macrophages; Neovascularization, Pathologic; Receptors, Cell Surface; Receptors, Scavenger; RNA, Messenger; Transcription, Genetic | 2006 |
Iron ions and haeme modulate the binding properties of complement subcomponent C1q and of immunoglobulins.
Topics: Complement Activation; Complement C1q; Enzyme-Linked Immunosorbent Assay; Heme; Humans; Immunoglobulins; Inflammation; Iron; Oxidative Stress; Reactive Oxygen Species; Rheumatoid Factor | 2007 |
Characterization of heme as activator of Toll-like receptor 4.
Topics: Animals; Cells, Cultured; Cytokines; Drug Antagonism; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase-1; Hemolysis; Immunity, Innate; Inflammation; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Neutrophils; Photosensitizing Agents; Protoporphyrins; Respiratory Burst; Signal Transduction; Toll-Like Receptor 4 | 2007 |
The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation.
Topics: Anemia, Hemolytic; Animals; Antimicrobial Cationic Peptides; Cells, Cultured; eIF-2 Kinase; Erythrocytes; Heme; Hepcidins; Homeostasis; Inflammation; Iron; Lipopolysaccharides; Liver; Macrophages; Male; Mice; Mice, Knockout; Phagocytosis; Signal Transduction; Spleen | 2007 |
The biological properties of etiocholanolone. Combined clinical staff conference at the National Institutes of Health.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Endotoxins; Etiocholanolone; Female; Fever; Heme; Humans; Inflammation; Leukocyte Count; Leukocytes; Male; Porphyrins; Propylene Glycols | 1967 |
Targets of nitric oxide in a mouse model of liver inflammation by Corynebacterium parvum.
Topics: Animals; Arginine; Blood; Blotting, Western; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Inflammation; Liver; Liver Diseases; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1995 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine | 1997 |
Heme and acute inflammation role in vivo of heme in the hepatic expression of positive acute-phase reactants in rats.
Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Base Sequence; Cytochrome P-450 Enzyme System; DNA Primers; Female; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Inflammation; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.
Topics: Animals; Capillary Permeability; Cell Adhesion Molecules; Chemotaxis, Leukocyte; Down-Regulation; Heme; Heme Oxygenase (Decyclizing); Immunohistochemistry; Inflammation; Liposomes; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Pancreas; Tissue Distribution | 2001 |
Neutrophil activation by heme: implications for inflammatory processes.
Topics: Actins; Animals; Chemotaxis, Leukocyte; Cytoskeleton; Enzyme Activation; Heme; Hemin; In Vitro Techniques; Inflammation; Interleukin-8; Male; Neutrophils; Pleurisy; Protein Kinase C; Rats; Rats, Wistar; Respiratory Burst; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Transcription, Genetic | 2002 |
Effect of blood on the activity and persistence of antigen induced inflammation in the rat air pouch.
Topics: Air; Animals; Antigens; Blood; Disease Models, Animal; Granulation Tissue; Heme; Hypersensitivity; Inflammation; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1985 |
[Clinical significance of quantitative serum hemopexin assessment as compared with that of haptoglobin].
Topics: Acute Disease; Beta-Globulins; Chronic Disease; Haptoglobins; Heme; Hemolysis; Humans; Inflammation; Liver Diseases; Neoplasms; Protein Binding | 1971 |
[The decrease of circulating serum hemopexins in non-hemolytic diseases].
Topics: Beta-Globulins; Hematologic Diseases; Heme; Hemolysis; Hemopexin; Humans; Immunodiffusion; Inflammation; Kidney Diseases; Liver Diseases; Neoplasms; Nephrosis | 1970 |
Plasma hemopexin homeostasis during the acute phase response.
Topics: Adult; Aged; Beta-Globulins; Female; Fractures, Bone; Haptoglobins; Heme; Hemolysis; Hemopexin; Homeostasis; Humans; Infections; Inflammation; Male; Middle Aged; Surgical Procedures, Operative; Transferrin | 1972 |