heme has been researched along with Genetic Predisposition in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 15 (53.57) | 24.3611 |
| 2020's | 8 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Aguet, F; Ardlie, K; Blackwell, T; Cade, BE; Chen, H; Durda, P; Gabriel, S; Gharib, SA; Goodman, MO; Gottlieb, DJ; Johnson, WC; Kurniansyah, N; Lin, X; Liu, Y; Purcell, SM; Redline, S; Reiner, AP; Rich, SS; Rotter, JI; Saxena, R; Smith, JD; Sofer, T; Taylor, KD; Tracy, R; Wang, H; Zhu, X | 1 |
| Akahoshi, K; Aoyagi, Y; Aragane, N; Asakage, T; Harada, Y; Ikeda, S; Ishikawa, T; Kano, Y; Kimura, K; Kinugasa, Y; Kumaki, Y; Matsudera, S; Mitsumura, T; Miyake, S; Nakagawa, T; Nakamura, H; Nakamura, R; Onishi, I; Ono, H; Oshima, N; Sato, A; Sueoka, E; Takagi, M; Takahashi, K; Takemoto, A; Tanabe, M; Tohyama, K; Tokunaga, M; Uetake, H | 1 |
| He, X; Liu, W; Lu, L; Pan, H; Tang, S; Wang, N; Yi, H; Zhang, M; Zhu, J | 1 |
| Ghazal, P; Hamilton, FW; Mitchell, RE; Somers, J; Timpson, NJ | 1 |
| Berisha, B; Kloeckl, L; List, W; Michelitsch, M; Pinter-Hausberger, S; Posch, F; Posch-Pertl, L; Renner, W; Weger, M | 1 |
| Bastarache, JA; DeBaun, MR; Kerchberger, VE; McNeil, JB; Rodeghier, M; Shaver, CM; Steinberg, MH; Ware, LB; Willen, SM | 1 |
| Deelen, J; Joshi, PK; Timmers, PRHJ; Wilson, JF | 1 |
| Aarsand, AK; Bustad, HJ; Fiorentino, V; Kallio, JP; Martinez, A; Sandberg, S; Schmitt, C; Vorland, M | 1 |
| Ananthakrishnan, AN; Chan, AT; de Silva, PS; Garber, JJ; Joshi, A; Khalili, H; Lochhead, P; Richter, JR; Sauk, J | 1 |
| Ang, J; Kalish, F; Kourula, S; Stevenson, DK; Sylvester, KG; Vandenabeele, P; Wong, RJ; Zhao, H | 1 |
| Barman-Aksözen, J; Huber, LC; Minder, E; Senn, JD | 1 |
| Anderson, KE; Chen, B; Desnick, RJ; Nazarenko, I; Weiss, Y; Yasuda, M | 1 |
| Brons, PP; Donker, AE; Dors, N; Knoers, NV; Raymakers, RA; Swinkels, DW; Terink, R; van Barneveld, T; Vlasveld, LT | 1 |
| Hammerman, C; Kaplan, M; Renbaum, P; Stevenson, DK; Vreman, HJ; Wong, RJ | 1 |
| Hnízda, A; Janošík, M; Kopecká, J; Kožich, V; Krijt, J; Melenovská, P; Raková, K; Wilcken, B | 1 |
| Farrag, MS; Kučerová, J; Martásek, P; Šeda, O; Šlachtová, L; Šperl, J | 1 |
| Fogelman, AM; Grijalva, V; Hama, S; Mehta, NU; Navab, M; Reddy, ST; Wagner, A | 1 |
| Gouya, L; Manceau, H; Puy, H | 1 |
| Al-Dous, EK; Arnold, M; Bhagwat, AM; Cotton, RJ; DeLisle, RK; El-Din Selim, MA; Engelke, R; Gieger, C; Gold, L; Grallert, H; Graumann, J; Kastenmüller, G; Lauc, G; Malek, J; Mohamoud, YA; Mook-Kanamori, DO; Peters, A; Pezer, M; Raffler, J; Sarwath, H; Strauch, K; Suhre, K; Thareja, G; Wahl, A | 1 |
| Bergdahl, IA; Broberg, K; Guo, W; Jin, T; Lei, L; Liang, Y; Nilsson, J; Skerfving, S; Tian, L; Zheng, G | 1 |
| Goldenstein, H; Levy, AP; Levy, NS | 1 |
| Balwani, M; Desnick, RJ | 1 |
| He, M; Hu, FB; Manson, JE; Qi, L; Workalemahu, T | 1 |
| Lidsky, TI; Schneider, JS | 1 |
| Frank, J; Merk, HF; Poblete-Gutiérrez, P; Wiederholt, T | 1 |
| Krost, B; Schubert, J | 1 |
| Brenner, DA; Scarlett, YV | 1 |
| Bacon, BR; Britton, RS; Fleming, RE; Jazwinska, EC; Roopenian, DC; Sly, WS; Sproule, TJ | 1 |
11 review(s) available for heme and Genetic Predisposition
| Article | Year |
|---|---|
HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review.
Topics: Communicable Diseases; Genetic Predisposition to Disease; Heme; Heme Oxygenase-1; Humans; Polymorphism, Genetic; Sepsis | 2022 |
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing.
Topics: Aging; Gene Expression; Genetic Predisposition to Disease; Genome-Wide Association Study; Heme; Humans; Longevity; Multifactorial Inheritance; Parents; Phenotype; Quantitative Trait Loci; Sex Factors | 2020 |
Acute Intermittent Porphyria: An Overview of Therapy Developments and Future Perspectives Focusing on Stabilisation of HMBS and Proteostasis Regulators.
Topics: Alleles; Animals; Combined Modality Therapy; Disease Management; Disease Susceptibility; Genetic Predisposition to Disease; Heme; Humans; Hydroxymethylbilane Synthase; Metabolic Networks and Pathways; Mutation; Porphyria, Acute Intermittent; Structure-Activity Relationship; Treatment Outcome | 2021 |
Dietary Iron and Heme Iron Consumption, Genetic Susceptibility, and Risk of Crohn's Disease and Ulcerative Colitis.
Topics: Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Genetic Predisposition to Disease; Heme; Humans; Iron, Dietary; Prognosis; Prospective Studies; Risk Assessment | 2017 |
[CME: Acute Intermittent Porphyria: When to Think of It? What Must be Checked? How to Treat?]
Topics: Arginine; Combined Modality Therapy; Diagnosis, Differential; Female; Genetic Predisposition to Disease; Heme; Hemin; Humans; Interdisciplinary Communication; Intersectoral Collaboration; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Prognosis; Recurrence; Risk Factors | 2018 |
Practice guidelines for the diagnosis and management of microcytic anemias due to genetic disorders of iron metabolism or heme synthesis.
Topics: Anemia, Hypochromic; Anemia, Iron-Deficiency; Anemia, Sideroblastic; Evidence-Based Medicine; Genetic Predisposition to Disease; Heme; Humans; Iron; Mutation; Practice Guidelines as Topic | 2014 |
Acute hepatic and erythropoietic porphyrias: from ALA synthases 1 and 2 to new molecular bases and treatments.
Topics: 5-Aminolevulinate Synthetase; Age Factors; Animals; Biomarkers; Chronic Pain; Enzyme Activation; Erythrocytes; Gene Expression Regulation; Genes, X-Linked; Genetic Association Studies; Genetic Predisposition to Disease; Heme; Humans; Mutation; Phenotype; Porphobilinogen Synthase; Porphyria, Erythropoietic; Porphyrias, Hepatic; RNA, Small Interfering | 2017 |
Haptoglobin genotype and its role in determining heme-iron mediated vascular disease.
Topics: Animals; Antioxidants; Diabetic Angiopathies; Genetic Predisposition to Disease; Haptoglobins; Heme; Hemoglobins; Humans; Iron; Oxidation-Reduction; Oxidative Stress; Phenotype; Polymorphism, Genetic; Vitamin E | 2012 |
The porphyrias: advances in diagnosis and treatment.
Topics: Biosynthetic Pathways; Genetic Predisposition to Disease; Heme; Humans; Mutation; Porphyrias | 2012 |
Lead neurotoxicity in children: basic mechanisms and clinical correlates.
Topics: Apoptosis; Bone and Bones; Brain; Calcium Signaling; Child; Child, Preschool; Cognition Disorders; Environmental Exposure; Female; Genetic Predisposition to Disease; Heme; Humans; Infant; Lead; Lead Poisoning, Nervous System, Childhood; Maternal Exposure; Maximum Allowable Concentration; Neuroglia; Neurotransmitter Agents; Pregnancy; Prenatal Exposure Delayed Effects; Social Class | 2003 |
Porphyrias.
Topics: Diagnosis, Differential; Enzymes; Genetic Predisposition to Disease; Heme; Humans; Porphyrias | 1998 |
17 other study(ies) available for heme and Genetic Predisposition
| Article | Year |
|---|---|
Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.
Topics: Aged; Datasets as Topic; Female; Genetic Predisposition to Disease; Heme; Humans; Iron; Male; Mendelian Randomization Analysis; Metabolic Networks and Pathways; Middle Aged; Polysomnography; Quantitative Trait Loci; Severity of Illness Index; Sleep Apnea, Obstructive; Up-Regulation | 2022 |
Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Heme; High-Throughput Nucleotide Sequencing; Humans; Japan; Male; Middle Aged; Mutation; Pancreatic Neoplasms; Young Adult | 2022 |
The role of the genetic variant FECH rs11660001 in the occurrence of anti-tuberculosis drug-induced liver injury.
Topics: Antitubercular Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Female; Ferrochelatase; Genetic Predisposition to Disease; Heme; Humans; Polymorphism, Single Nucleotide; Tuberculosis | 2022 |
Heme oxygenase-1 gene rs2071746 polymorphism in retinal vein occlusion.
Topics: Case-Control Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heme; Heme Oxygenase-1; Humans; Polymorphism, Single Nucleotide; Retinal Vein Occlusion; Risk Factors | 2022 |
Haptoglobin genotype predicts severe acute vaso-occlusive pain episodes in children with sickle cell anemia.
Topics: Acute Chest Syndrome; Acute Pain; Adolescent; Alleles; Anemia, Sickle Cell; Arterial Occlusive Diseases; Child; Child, Preschool; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haptoglobins; Heme; Humans; Incidence; Prospective Studies; Risk; Young Adult | 2020 |
Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Cell Survival; Disease Models, Animal; Erythroblastosis, Fetal; Erythrocytes; Genetic Predisposition to Disease; Heme; Heme Oxygenase-1; Hemolysis; Hemopexin; Heterozygote; Lipid Peroxidation; Liver; Membrane Proteins; Methemalbumin; Mice; Mice, Knockout; NIH 3T3 Cells; Oxidative Stress; Phenotype; Promoter Regions, Genetic; Protein Binding; Time Factors | 2017 |
Porphyria cutanea tarda and hepatoerythropoietic porphyria: Identification of 19 novel uroporphyrinogen III decarboxylase mutations.
Topics: Child; Family; Genetic Carrier Screening; Genetic Heterogeneity; Genetic Predisposition to Disease; Heme; Humans; Male; Molecular Diagnostic Techniques; Mutation; Porphyria Cutanea Tarda; Porphyria, Hepatoerythropoietic; Uroporphyrinogen Decarboxylase | 2019 |
Heme oxygenase-1 promoter polymorphisms and neonatal jaundice.
Topics: Bilirubin; Biomarkers; Carboxyhemoglobin; Case-Control Studies; Databases, Factual; Gene Frequency; Genetic Predisposition to Disease; Glucosephosphate Dehydrogenase Deficiency; Glucuronosyltransferase; Heme; Heme Oxygenase-1; Hemolysis; Homozygote; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic | 2014 |
Chaperone therapy for homocystinuria: the rescue of CBS mutations by heme arginate.
Topics: Animals; Arginine; Catalytic Domain; CHO Cells; Cricetulus; Cystathionine beta-Synthase; Female; Fibroblasts; Genetic Predisposition to Disease; Heme; Homocystinuria; Homozygote; Humans; Models, Molecular; Molecular Chaperones; Mutation; Phenotype; Protein Conformation; Protein Folding; Proteostasis Deficiencies; Structure-Activity Relationship; Substrate Specificity; Transfection | 2015 |
A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease.
Topics: Adolescent; Adult; Amino Acid Sequence; Base Sequence; Biosynthetic Pathways; Czech Republic; DNA; DNA Mutational Analysis; Erythrocytes; Family; Female; Ferrochelatase; Genetic Predisposition to Disease; Genome, Human; Heme; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Polymorphism, Genetic; Protoporphyria, Erythropoietic; Protoporphyrins | 2015 |
Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; Cells, Cultured; Cholesterol; Coculture Techniques; Disease Models, Animal; Female; Genetic Predisposition to Disease; Heme; Hemopexin; Humans; Inflammation Mediators; Lipoproteins, HDL; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; Reactive Oxygen Species; Signal Transduction | 2016 |
Connecting genetic risk to disease end points through the human blood plasma proteome.
Topics: Alleles; Blood Proteins; Complement System Proteins; Drug Delivery Systems; Endpoint Determination; Gene Regulatory Networks; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Genome, Human; Glycoproteins; Heme; Humans; Molecular Sequence Annotation; Pharmacogenetics; Protein Processing, Post-Translational; Proteome; Quantitative Trait Loci; Reproducibility of Results; Risk Factors; RNA Splicing; RNA, Messenger | 2017 |
δ-Aminolevulinic acid dehydratase genotype predicts toxic effects of lead on workers' peripheral nervous system.
Topics: Adolescent; Adult; Case-Control Studies; China; Electric Power Supplies; Female; Gene Frequency; Genetic Predisposition to Disease; Heme; Homozygote; Humans; Kidney; Lead; Lead Poisoning, Nervous System, Adult; Linear Models; Male; Median Neuropathy; Middle Aged; Neural Conduction; Neurologic Examination; Occupational Diseases; Occupational Exposure; Peroneal Neuropathies; Phenotype; Polymorphism, Genetic; Porphobilinogen Synthase; Receptors, Calcitriol; Risk Assessment; Risk Factors; Sensation; Ulnar Neuropathies; Young Adult | 2011 |
Genetic determinants for body iron store and type 2 diabetes risk in US men and women.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Genetic Association Studies; Genetic Predisposition to Disease; Health Personnel; Heme; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Iron; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Risk Factors; Transferrin; United States | 2012 |
[Laboratory tests and therapeutic strategies for the porphyrias].
Topics: Algorithms; Arginine; Critical Care; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Genetic Predisposition to Disease; Heme; Humans; Photosensitivity Disorders; Porphyria Cutanea Tarda; Porphyrias | 2006 |
[Prevention of cleft lip and palate. Reducing risk of recurrence--a 25-year clinical experience].
Topics: Adolescent; Adult; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Gestational Age; Heme; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Prenatal Care; Prospective Studies; Risk; Secondary Prevention; Vitamin B Complex | 2006 |
Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice.
Topics: Aging; Animals; beta 2-Microglobulin; Crosses, Genetic; Female; Genetic Linkage; Genetic Predisposition to Disease; Genetic Variation; Heme; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Iron; Iron Overload; Liver; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Phenotype; Sex Characteristics; Sex Chromosomes | 2001 |