heme has been researched along with Disease Models, Animal in 193 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (9.33) | 18.7374 |
| 1990's | 11 (5.70) | 18.2507 |
| 2000's | 43 (22.28) | 29.6817 |
| 2010's | 101 (52.33) | 24.3611 |
| 2020's | 20 (10.36) | 2.80 |
| Authors | Studies |
|---|---|
| Britton, WJ; Kikuchi, K; Luo, K; Oehlers, SH; Stocker, R | 1 |
| Alemi, PS; Ashrafi, A; Dey, S; Ghosh, P; Jain, N; Kalainayakan, SP; Kim, JW; Konduri, PC; Salamat, N; Vidal, C; Zhang, L | 1 |
| Alattar, AG; Chen, J; Chen, JJ; Flygare, J; Gram, M; Karlsson, H; Mattebo, A; Siva, K; Sjögren, SE; Soneji, S; Tedgård, U | 1 |
| Córdoba, KM; Fontanellas, A; Jericó, D; Parra-Guillen, ZP; Trocóniz, IF; Vera-Yunca, D | 1 |
| Cai, J; Chen, J; Fan, C; Guo, D; Hu, C; Jia, Z; Li, S; Sun, Y; Xu, Z; Zhang, H; Zhang, R; Zhong, D | 1 |
| Abdulla, F; Belcher, JD; Chen, C; Conglin, R; Cummings, J; Dudler, T; Ivy, ZK; Nguyen, J; Vercellotti, GM | 1 |
| Cortegano, I; de Andrés, B; Egido, J; García-Caballero, C; Gaspar, ML; González-Guerrero, C; Guerrero-Hue, M; Herencia, C; Moreno, JA; Morgado-Pascual, JL; Opazo-Rios, L; Rayego-Mateos, S; Vallejo-Mudarra, M; Vázquez-Carballo, C | 1 |
| Banerjee, B; Bortolussi, G; Muro, AF; Olajide, OJ | 1 |
| Fox, JW; Gutiérrez, JM; Rucavado, A; Wase, N | 1 |
| Chen, W; Dunn, LL; Kong, SMY; Nadel, J; Newington, DL; Stanley, CP; Stocker, R; Tumanov, S; Vigder, N; Wang, XS | 1 |
| Fuke, N; Keleku-Lukwete, N; Kuga, A; Panda, H; Suganuma, H; Suzuki, M; Yamamoto, M | 1 |
| Frank, MW; Jackowski, S; Rock, CO; Subramanian, C; Yao, J | 1 |
| Bafligil, C; Becker, CM; Charles, P; Dakin, SG; De Leo, B; Elger, B; Fischer, OM; Hess-Stumpp, H; Kennedy, S; Kessler, BM; Laux-Biehlmann, A; Manek, S; Martinez, FE; Morten, K; Mueller, J; Oppermann, U; Rahmioglu, N; Shang, C; Steers, G; Steinmeyer, A; Tapmeier, T; Thézénas, ML; Zollner, TM; Zondervan, KT | 1 |
| Ackah, EB; Crosby, D; Flage, B; Ghosh, S; Hazra, R; Lenhart, D; Ofori-Acquah, SF; Orikogbo, OO; Owusu-Dabo, E; Paintsil, V; Tan, RJ; Vitturi, DA | 1 |
| Eccles, CA; James, J; Kurdyukov, S; Niihori, M; Rafikov, R; Rafikova, O; Varghese, MV | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; 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| Han, G; Keller, NP; Lu, L; Sang, H; Song, J; Zhai, P; Zhang, C; Zhang, Y | 1 |
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| Arch, DD; Bergeron, M; Franklin, MR; Hathaway, L; Kushner, JP; Phillips, JD | 1 |
| Afonso, SG; Batlle, A; Buzaleh, AM; Martinez, Mdel C; Meiss, RP | 1 |
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| Gearinger, RL; Justice, SS; Mason, KM; Raffel, FK; Sharpe, SW; Szelestey, BR; Vogel, AR | 1 |
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| Coluccio-Leskow, F; De Luca, P; De Siervi, A; Elguero, B; Giudice, J; Gueron, G; Meiss, R; Navone, N; Toscani, MA; Vazquez, E; Zalazar, F | 1 |
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| Atlas, SW; Thulborn, KR | 1 |
| Dolan, KG; Garrick, LM; Garrick, MD; Kulju, D; Romano, MA; Scott, D | 1 |
| Nakayama, K; Ohyama, T; Okui, T; Takasawa, A; Tamura, M; Terai, I | 1 |
| Akagi, R; Fujiwara, T; Hirakawa, M; Suzuki, T; Takahashi, T; Yamasaki, A | 1 |
| Alonso-Alija, C; Apeler, H; Becker, EM; Dembowsky, K; Feurer, A; Gerzer, R; Minuth, T; Perzborn, E; Pleiss, U; Schramm, M; Schröder, H; Schroeder, W; Stahl, E; Stasch, JP; Steinke, W; Straub, A | 1 |
| Halpern, NA; Sedlacek, M; Uribarri, J | 1 |
| Payne, SM; Redford, P; Torres, AG; Welch, RA | 1 |
| Freedman, ML; Rosman, J | 1 |
| Rifkind, AB | 1 |
| De Matteis, F; Stonard, M | 1 |
| Kneip, TJ; Mallon, RP; Rulon, VP | 1 |
| Bickers, DR; Harber, LC; Kappas, A; Keogh, L | 1 |
| Aruoma, OI; Evans, PJ; Halliwell, B; Konijn, AM; Peters, TJ; Raja, KB; Simpson, RJ | 1 |
| Oyedeji, CO; Vassilopoulou-Sellin, R | 1 |
| Gale, R; Rodgers, PA; Stevenson, DK; Vreman, HJ | 1 |
| Ríos de Molina, MC; San Martín de Viale, LC; Wainstok de Calmanovici, R | 1 |
| Sweeney, GD | 1 |
| Correia, MA; Litman, DA | 1 |
| Bacon, PA; Blake, DR; Hewitt, S; Morris, C; Yoshino, S | 1 |
| Goyer, RA | 1 |
| Engel, P; Marver, HS; Pimstone, NR; Schmid, R; Seitz, PT; Tenhunen, R | 1 |
| Lorkin, PA | 1 |
| Aschenbrenner, V; Cutilletta, AF; Rabinowitz, M; Zak, R | 1 |
16 review(s) available for heme and Disease Models, Animal
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
A Dual Role of Heme Oxygenase-1 in Cancer Cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Disease Models, Animal; Drug Therapy; Heme; Heme Oxygenase-1; Humans; Iron; Lipid Peroxidation; Neoplasms; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2018 |
Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis.
Topics: Animals; Disease Models, Animal; Embryonic Development; Erythropoiesis; Heme; Humans; Iron; Mice; Zebrafish | 2019 |
The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.
Topics: Animals; Disease Models, Animal; Hematologic Diseases; Hematologic Neoplasms; Heme; Hemoglobins; Humans; Ribosomes; Tumor Suppressor Protein p53 | 2014 |
Role of Exercise-Induced Oxidative Stress in Sickle Cell Trait and Disease.
Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Exercise; Heme; Hemoglobin, Sickle; Hemolysis; Humans; Hypoxia; Iron; Mice; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Reperfusion Injury; Sickle Cell Trait; Xanthine Oxidase | 2016 |
Localized delivery of carbon monoxide.
Topics: Administration, Cutaneous; Administration, Inhalation; Administration, Oral; Animals; Biliverdine; Carbon Monoxide; Carboxyhemoglobin; Coronary Artery Disease; Diabetes Mellitus; Disease Models, Animal; Drug Delivery Systems; Heme; Heme Oxygenase-1; Humans; Organ Transplantation; Organometallic Compounds; Reperfusion Injury; Signal Transduction; Tissue Distribution | 2017 |
A central role for free heme in the pathogenesis of severe malaria: the missing link?
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Hemoglobins; Humans; Malaria; Malaria, Cerebral; Models, Biological | 2008 |
Pleiotropic neuroprotective and metabolic effects of Actovegin's mode of action.
Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Heme; Humans; Nervous System Diseases; Neuroprotective Agents; NF-kappa B; Signal Transduction | 2012 |
The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology.
Topics: Animals; Cross-Linking Reagents; Disease Models, Animal; Free Radicals; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Hydrogen Peroxide; Leghemoglobin; Mice; Mice, Knockout; Models, Chemical; Myoglobin; Oxidation-Reduction; Oxygen; Peroxides; Spectrophotometry; Temperature | 2004 |
Mechanisms of haem and non-haem iron absorption: lessons from inherited disorders of iron metabolism.
Topics: Absorption; Animals; Biological Transport; Cation Transport Proteins; Disease Models, Animal; Erythropoiesis; Heme; Hepatocytes; Humans; Intestinal Mucosa; Iron; Iron Metabolism Disorders; Iron Overload; Iron-Binding Proteins; Macrophages; Mice; Models, Biological; Mutation | 2005 |
Nitric oxide-independent stimulation of soluble guanylate cyclase with BAY 41-2272 in cardiovascular disease.
Topics: Animals; Antihypertensive Agents; Benzoates; Cardiovascular Diseases; Cell Adhesion; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Heart Failure; Heme; Humans; Hypertension; Hypertension, Pulmonary; Inflammation; Leukocytes; Nitric Oxide; Platelet Aggregation; Pyrazoles; Pyridines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilator Agents | 2007 |
Lead hepatotoxicity & potential health effects.
Topics: Animals; Chelating Agents; Cholesterol; Cytochrome P-450 Enzyme System; Disease Models, Animal; Environmental Exposure; Heme; Humans; Hyperplasia; Lead; Lead Poisoning; Liver; Occupational Exposure; Oxidative Stress | 2007 |
Porphyria cutanea tarda.
Topics: Age Factors; Animals; Disease Models, Animal; Erythropoiesis; Heme; Hexachlorobenzene; Humans; Hydrocarbons, Halogenated; Iron; Kidney Failure, Chronic; Liver; Photosensitivity Disorders; Porphyrias; Renal Dialysis; Skin Diseases; Skin Pigmentation; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1982 |
Biochemical and molecular aspects of genetic disorders of bilirubin metabolism.
Topics: Animals; Anion Transport Proteins; Bile; Bilirubin; Carrier Proteins; Disease Models, Animal; Glucuronosyltransferase; Heme; Humans; Hyperbilirubinemia, Hereditary; Rats; Rats, Gunn | 1998 |
Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases.
Topics: Animals; Bloodletting; Carboxy-Lyases; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Heme; Hexachlorobenzene; Humans; Hydroxamic Acids; Iron; Lead Poisoning; Male; Mice; Polychlorinated Dibenzodioxins; Porphyrias; Porphyrins; Rats; Skin Diseases; Uroporphyrinogen Decarboxylase | 1986 |
Fetal and embryonic haemoglobins.
Topics: Amino Acid Sequence; Anemia; Animals; Chromosome Aberrations; Chromosome Disorders; Disease Models, Animal; Female; Fetal Hemoglobin; Genes; Genotype; Goats; Heme; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Immunoglobulin Fragments; Male; Mutation; Oxygen; Pregnancy; Sheep | 1973 |
1 trial(s) available for heme and Disease Models, Animal
177 other study(ies) available for heme and Disease Models, Animal
| Article | Year |
|---|---|
Haem oxygenase limits Mycobacterium marinum infection-induced detrimental ferrostatin-sensitive cell death in zebrafish.
Topics: Animals; Cell Death; Cyclohexylamines; Disease Models, Animal; Heme; Heme Oxygenase-1; Homeostasis; Host-Pathogen Interactions; Humans; Iron; Macrophages; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Mycobacterium tuberculosis; Phenylenediamines; Tuberculosis; Zebrafish; Zebrafish Proteins | 2022 |
Heme Sequestration Effectively Suppresses the Development and Progression of Both Lung Adenocarcinoma and Squamous Cell Carcinoma.
Topics: Adenocarcinoma of Lung; Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Heme; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID | 2022 |
Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia.
Topics: Alpha-Globulins; Anemia, Diamond-Blackfan; Animals; Cells, Cultured; Disease Models, Animal; Female; Gene Deletion; Gene Silencing; Genetic Therapy; Heme; Humans; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Recombinant Proteins; Ribosomal Proteins | 2022 |
Mechanistic modelling of enzyme-restoration effects of new recombinant liver-targeted proteins in acute intermittent porphyria.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Heme; Mice; Mice, Inbred C57BL; Porphyria, Acute Intermittent; Recombinant Proteins | 2022 |
Inhibition of mPGES-2 ameliorates NASH by activating NR1D1 via heme.
Topics: Animals; Disease Models, Animal; Heme; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Prostaglandin-E Synthases | 2023 |
MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Antibodies, Monoclonal; Complement Activation; Disease Models, Animal; E-Selectin; Heme; Hemoglobins; Hemolysis; Hypoxia; Inflammation; Intercellular Adhesion Molecule-1; Mannose-Binding Lectins; Mannose-Binding Protein-Associated Serine Proteases; Mice; NF-kappa B; Vascular Cell Adhesion Molecule-1; Volatile Organic Compounds | 2022 |
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury.
Topics: Animals; Disease Models, Animal; Heme; Hemolysis; Inflammation; Mice; Mice, Knockout; NF-kappa B; Phenylhydrazines; Sulfonamides; Toll-Like Receptor 4 | 2022 |
Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity.
Topics: Animals; Bilirubin; Disease Models, Animal; Glucuronosyltransferase; Heme; Hyperbilirubinemia; Liver; Mice | 2022 |
Longitudinal Metabolomics and Lipidomics Analyses Reveal Alterations Associated with Envenoming by
Topics: Amino Acids; Animals; Antivenins; Bothrops; Crotalid Venoms; Daboia; Disease Models, Animal; Heme; Hydrocortisone; Lipidomics; Mice; Purines; Pyrimidines; RNA, Transfer; Triglycerides; Venoms | 2022 |
Destabilization of Atherosclerotic Plaque by Bilirubin Deficiency.
Topics: Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Bilirubin; Cardiovascular Diseases; Constriction, Pathologic; Disease Models, Animal; Heme; Hemorrhage; Humans; Lipids; Mice; Plaque, Atherosclerotic; Proteomics | 2023 |
Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model.
Topics: Anemia, Sickle Cell; Animals; Dietary Supplements; Disease Models, Animal; Female; Heme; Humans; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver; Liver Diseases; Male; Mice; Mice, Transgenic; NF-E2-Related Factor 2; Sulfoxides | 2019 |
A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction.
Topics: Animals; Apoptosis Regulatory Proteins; Brain; Brain Chemistry; Coenzyme A; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation; Heme; Hemoglobins; Humans; Male; Mice; Mice, Knockout; Neurons; Oxidation-Reduction; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Repressor Proteins | 2020 |
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.
Topics: Aldehydes; Allyl Compounds; Amine Oxidase (Copper-Containing); Analgesics; Animals; Biomarkers; Cell Adhesion Molecules; Disease Models, Animal; Endometriosis; Female; Gene Expression Profiling; Heme; Humans; Inflammation Mediators; Interleukin-8; Iron; Lipid Peroxidation; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Myeloid Cells; Oxidative Stress; Peritoneal Diseases; Phagocytosis; Sulfonamides | 2020 |
Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
Topics: Acute Kidney Injury; Anemia, Sickle Cell; Animals; Biopsy; Disease Models, Animal; Disease Progression; Disease Susceptibility; Erythrocytes; Glomerular Filtration Rate; Heme; Hemopexin; Humans; Kidney Function Tests; Mice; Models, Biological | 2020 |
Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability.
Topics: Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Disease Progression; Endothelial Cells; Female; Heme; Hemolysis; HSP27 Heat-Shock Proteins; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Rats, Sprague-Dawley; Sex Characteristics; Tight Junctions | 2020 |
Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.
Topics: Animals; Disease Models, Animal; Female; Heme; Hemolysis; Humans; In Vitro Techniques; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Phagocytes; Phagocytosis; Phenotype; RNA-Seq; Single-Cell Analysis; Spherocytosis, Hereditary | 2020 |
Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis.
Topics: Animals; Chemokine CXCL1; Disease Models, Animal; Heme; Hemolysis; Humans; Macrophages; Mice; Mice, Knockout; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Syk Kinase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
Protective response against
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Bacterial Load; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Vaccines; Disease Models, Animal; Female; Heme; Humans; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Sepsis | 2021 |
Conserved Epigenetic Programming and Enhanced Heme Metabolism Drive Memory B Cell Reactivation.
Topics: Animals; B-Lymphocytes; Cell Differentiation; Cellular Reprogramming; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Profiling; Heme; Humans; Immunity, Humoral; Immunologic Memory; Influenza A virus; Influenza, Human; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections | 2021 |
Effect of hemopexin treatment on outcome after intracerebral hemorrhage in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Cell Death; Cerebral Hemorrhage; Corpus Striatum; Disease Models, Animal; Female; Heme; Heme Oxygenase-1; Hemoglobins; Hemopexin; Injections, Intraperitoneal; Male; Mice; Treatment Outcome | 2021 |
Acute Hemolysis and Heme Suppress Anti-CD40 Antibody-Induced Necro-Inflammatory Liver Disease.
Topics: Albumins; Animals; Antibodies; Biopsy; CD40 Antigens; Disease Models, Animal; Disease Susceptibility; Erythrocytes; Gene Expression Profiling; Heme; Hemolysis; Hepatitis; Iron; Macrophages; Mice; Mice, Knockout; Phenylhydrazines; Porphyrins; Protein Binding | 2021 |
Fluorouracil Enhances Photodynamic Therapy of Squamous Cell Carcinoma via a p53-Independent Mechanism that Increases Protoporphyrin IX levels and Tumor Cell Death.
Topics: Animals; Biosynthetic Pathways; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Heme; Humans; Mice; Photochemotherapy; Protoporphyrins; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2017 |
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen.
Topics: Anemia, Hypochromic; Animals; Base Sequence; Biosynthetic Pathways; Coproporphyria, Hereditary; Coproporphyrinogen Oxidase; Disease Models, Animal; Ethylnitrosourea; Fasting; Feces; Female; Heme; Male; Mice, Mutant Strains; Mutagenesis; Mutation; Phenobarbital; Phenotype; Pregnancy | 2017 |
Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption.
Topics: Administration, Oral; Anemia, Iron-Deficiency; Animals; Disease Models, Animal; Duodenum; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Heme; Heme Oxygenase-1; Humans; Swine | 2017 |
Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury.
Topics: 5-Aminolevulinate Synthetase; Acute Kidney Injury; Animals; Basic-Leucine Zipper Transcription Factors; Cytosol; Disease Models, Animal; Gene Expression Regulation; Glycerol; Heme; Heme Oxygenase (Decyclizing); Humans; Male; Rats; Repressor Proteins; Rhabdomyolysis | 2017 |
Characterization of a novel streptococcal heme-binding protein SntA and its interaction with host antioxidant protein AOP2.
Topics: Animals; Bacterial Proteins; Brain; Carrier Proteins; Disease Models, Animal; Female; Gene Expression Profiling; Gene Knockout Techniques; Heme; Heme-Binding Proteins; Hemeproteins; Hemoglobins; Host-Pathogen Interactions; Lung; Oxidation-Reduction; Peroxiredoxin VI; Protein Binding; Protein Interaction Domains and Motifs; Recombinant Proteins; Streptococcal Infections; Streptococcus suis; Swine; Two-Hybrid System Techniques; Virulence | 2017 |
Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Cell Survival; Disease Models, Animal; Erythroblastosis, Fetal; Erythrocytes; Genetic Predisposition to Disease; Heme; Heme Oxygenase-1; Hemolysis; Hemopexin; Heterozygote; Lipid Peroxidation; Liver; Membrane Proteins; Methemalbumin; Mice; Mice, Knockout; NIH 3T3 Cells; Oxidative Stress; Phenotype; Promoter Regions, Genetic; Protein Binding; Time Factors | 2017 |
Use of immunoproteomics to identify immunogenic proteins in a rat model of acute respiratory distress syndrome.
Topics: Animals; Autoantibodies; Cecum; Choline; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gluconeogenesis; Glycolysis; Heme; Humans; Lung; Male; NAD; Punctures; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Signal Transduction | 2017 |
Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.
Topics: Anemia; Anemia, Sickle Cell; Animals; Antioxidants; Dimethyl Fumarate; Disease Models, Animal; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Heme; Humans; Inflammation; Leukemia, Erythroblastic, Acute; Mice; NF-E2-Related Factor 2; RNA, Messenger; Spleen | 2017 |
Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells.
Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Survival; Cysteine Dioxygenase; Disease Models, Animal; Heme; Heterografts; Humans; Iron; Mice; Models, Biological; Piperazines; Proto-Oncogene Proteins c-myb; Reactive Oxygen Species; Stomach Neoplasms | 2017 |
Scavenging Reactive Oxygen Species Production Normalizes Ferroportin Expression and Ameliorates Cellular and Systemic Iron Disbalances in Hemolytic Mouse Model.
Topics: Animals; Antioxidants; Cation Transport Proteins; Disease Models, Animal; Heme; Hemolysis; Iron; Lipopolysaccharides; Macrophages; Mice; Oxidative Stress; Reactive Oxygen Species; Spleen | 2018 |
Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Citrullination; Crush Syndrome; Disease Models, Animal; DNA; Extracellular Traps; Heme; Histones; Humans; Macrophages; Mice; Muscle, Skeletal; Myoglobin; Platelet Activation; Reactive Oxygen Species; Rhabdomyolysis; Secretory Vesicles | 2018 |
Free Heme and Amyloid-β: A Fatal Liaison in Alzheimer's Disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Heme; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Oxidation-Reduction; Peptide Fragments; Peroxidases | 2018 |
Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Eryptosis; Erythrocyte Aggregation; Erythrocytes; Heme; Hemolysis; Humans; Mice; Phosphatidylserines; Protein Binding; Proteins; Sepsis; Thrombosis; Zinc Compounds | 2018 |
Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cells, Cultured; Disease Models, Animal; E-Selectin; Erythrocytes; Female; Heme; Hemolysis; Hepatitis A Virus Cellular Receptor 1; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Ki-67 Antigen; Kidney; Lipocalin-2; Mice; Mice, Inbred C57BL; Phenylhydrazines; Vascular Diseases | 2018 |
Heme oxygenase-1 deficiency promotes severity of sepsis in a non-surgical preterm mouse model.
Topics: Anemia, Hemolytic; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cecum; Crosses, Genetic; Disease Models, Animal; Female; Growth Disorders; Heme; Heme Oxygenase-1; Humans; Infant, Premature; Iron Metabolism Disorders; Membrane Proteins; Mice; Mice, Knockout; Sepsis | 2018 |
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
Topics: Acute Kidney Injury; Anemia, Sickle Cell; Animals; Cell-Free System; Complement C3; Complement Membrane Attack Complex; Disease Models, Animal; Endothelial Cells; Erythrocytes; Female; Heme; Hemolysis; Hemopexin; Hepatitis A Virus Cellular Receptor 1; Kidney; Mice; Mice, Inbred C57BL; P-Selectin; Receptor, Anaphylatoxin C5a; Receptors, G-Protein-Coupled | 2018 |
Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Cell Line; Chinchilla; Cytoplasm; Disease Models, Animal; Ear, Middle; Haemophilus Infections; Haemophilus influenzae; Heme; Humans; Iron; Otitis Media; Pinocytosis; Protein Transport | 2018 |
Systemic messenger RNA as an etiological treatment for acute intermittent porphyria.
Topics: Animals; Disease Models, Animal; Female; Genetic Therapy; Haploinsufficiency; Heme; Hepatocytes; Humans; Hydroxymethylbilane Synthase; Liver; Male; Porphyria, Acute Intermittent; RNA, Messenger | 2018 |
Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence.
Topics: Animals; Chinchilla; Disease Models, Animal; Ear, Middle; Haemophilus Infections; Haemophilus influenzae; Heme; Humans; Iron Deficiencies; Otitis Media; Otitis Media with Effusion; Phosphoric Diester Hydrolases; Virulence | 2018 |
Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1.
Topics: Animals; Atypical Hemolytic Uremic Syndrome; Biopsy; Complement Activation; Complement C3; Disease Models, Animal; Disease Susceptibility; Endothelial Cells; Endothelium, Vascular; Female; Heme; Heme Oxygenase-1; Hemolysis; Human Umbilical Vein Endothelial Cells; Humans; Kidney Glomerulus; Kruppel-Like Factor 4; Membrane Proteins; Mice; Mice, Inbred C57BL; Microvessels; Primary Cell Culture; Thrombomodulin; Up-Regulation | 2018 |
Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
Topics: Acetylcholine; Animals; Disease Models, Animal; Female; Heme; Hydroxymethylbilane Synthase; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Phenobarbital; Phenylephrine; Porphyria, Acute Intermittent; Sex Factors; Vasodilation | 2019 |
Genistein suppresses psoriasis-related inflammation through a STAT3-NF-κB-dependent mechanism in keratinocytes.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Disease Models, Animal; Genistein; Heme; Humans; Imiquimod; Inflammation Mediators; Keratinocytes; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2019 |
P-selectin plays a role in haem-induced acute lung injury in sickle mice.
Topics: Acute Lung Injury; Anemia, Sickle Cell; Animals; Disease Models, Animal; Heme; Mice; Mice, Mutant Strains; P-Selectin | 2019 |
P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner.
Topics: Alanine Transaminase; Anemia, Sickle Cell; Animals; Complement Activation; Complement C3; Disease Models, Animal; Endothelium, Vascular; Gene Silencing; Heme; Hemolysis; Humans; Lipocalin-2; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Phenylhydrazines; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Role of the kidneys in the redistribution of heme-derived iron during neonatal hemolysis in mice.
Topics: Animals; Bilirubin; Disease Models, Animal; Erythrocytes; Heme; Heme Oxygenase-1; Hemolysis; Iron; Kidney; Male; Mice | 2019 |
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinking Water; Eating; Feces; Heme; Lipid Peroxidation; Male; Meat; Nitrites; Nitroso Compounds; Rats, Inbred F344; Saliva; Sodium Nitrite; Thiobarbituric Acid Reactive Substances | 2013 |
Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases.
Topics: Anemia, Sickle Cell; Animals; beta-Thalassemia; Cardiovascular System; Disease Models, Animal; Endothelium, Vascular; Heme; Hemopexin; Mice; Mice, Knockout; Mice, SCID; Nitric Oxide; Reactive Oxygen Species; Treatment Outcome | 2013 |
Heme deficiency of soluble guanylate cyclase induces gastroparesis.
Topics: Animals; Disease Models, Animal; Gastric Mucosa; Gastrointestinal Motility; Gastroparesis; Gene Knock-In Techniques; Guanylate Cyclase; Heme; Mice; Nitric Oxide; Oxidative Stress; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2013 |
The response of cerebral cortex to haemorrhagic damage: experimental evidence from a penetrating injury model.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Benzothiazoles; Brain; Brain Injuries; Cell Death; Cerebral Cortex; Congo Red; Disease Models, Animal; Female; Ferrocyanides; Heme; Hemorrhage; Hippocampus; Humans; Immunohistochemistry; Male; Neocortex; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins; Temporal Lobe; Thiazoles; Wounds, Penetrating | 2013 |
Cilostazol inhibits accumulation of triglycerides in a rat model of carotid artery ligation.
Topics: Animals; Cardiovascular Agents; Carotid Artery, Common; Carotid Stenosis; Cholesterol, HDL; Cilostazol; Disease Models, Animal; Heme; Hemodynamics; Ligation; Male; Phosphodiesterase 3 Inhibitors; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tetrazoles; Time Factors; Triglycerides | 2013 |
Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model.
Topics: Animals; Animals, Newborn; Apoptosis; Collagen Type XVIII; Disease Models, Animal; Enterocolitis, Necrotizing; Genotype; Heme; Heme Oxygenase-1; Hypoxia; Ileum; Injury Severity Score; Interleukin-1beta; Intestinal Mucosa; Jejunum; Matrix Metalloproteinase 2; Membrane Proteins; Mice; Mice, Knockout; Mucous Membrane; P-Selectin; Transcription, Genetic | 2013 |
Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene.
Topics: Amino Acid Substitution; Animals; Cataract; Coproporphyrinogen Oxidase; Coproporphyrins; Disease Models, Animal; Eye Diseases, Hereditary; Female; Heme; Homozygote; Male; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Mice, Transgenic; Mutation, Missense; Phenotype; Polymerase Chain Reaction; RNA, Messenger | 2013 |
Correlation between Plasmodium yoelii nigeriensis susceptibility to artemisinin and alkylation of heme by the drug.
Topics: Alkylation; Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Female; Heme; Malaria; Mice; Plasmodium yoelii; Protein Binding; Spleen | 2013 |
Effect of iron liposomes on anemia of inflammation.
Topics: Administration, Oral; Anemia, Iron-Deficiency; Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Ferric Compounds; Hematinics; Heme; Hepcidins; Inflammation; Intestinal Absorption; Iron; Liposomes; Male; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical; Time Factors; Ultrasonics | 2013 |
Paradoxical effects of heme arginate on survival of myocutaneous flaps.
Topics: Animals; Arginine; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Myocutaneous Flap; Necrosis; Rats; Rats, Inbred Lew; Reperfusion Injury; Skin | 2014 |
Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging.
Topics: Animals; Antineoplastic Agents; Biomarkers; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Erlotinib Hydrochloride; Glioma; Heme; Heterografts; Humans; Mice; Molecular Imaging; Neovascularization, Pathologic; Optical Imaging; Permeability; Pharmaceutical Preparations; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase Inhibitors; Quinazolines; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Haemophilus responses to nutritional immunity: epigenetic and morphological contribution to biofilm architecture, invasion, persistence and disease severity.
Topics: Animals; Biofilms; Chinchilla; Disease Models, Animal; Epigenesis, Genetic; Haemophilus; Haemophilus Infections; Heme; Humans; Iron; Otitis Media; Severity of Illness Index; Time Factors | 2013 |
Comparison of transcription of the Haemophilus influenzae iron/heme modulon genes in vitro and in vivo in the chinchilla middle ear.
Topics: Animals; Chinchilla; Disease Models, Animal; Ear, Middle; Gene Expression Regulation, Bacterial; Haemophilus influenzae; Heme; Iron; Oligonucleotide Array Sequence Analysis; Operon; Otitis Media; Regulon; Transcription, Genetic; Transcriptome | 2013 |
Serum resistance, gallium nitrate tolerance and extrapulmonary dissemination are linked to heme consumption in a bacteremic strain of Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Bacteremia; Blood Bactericidal Activity; Cattle; Disease Models, Animal; Drug Resistance, Bacterial; Female; Gallium; Heme; Humans; Mice, Inbred C57BL; Pneumonia, Bacterial; Serum | 2014 |
Protective action of antioxidants on hepatic damage induced by griseofulvin.
Topics: Animals; Antifungal Agents; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Griseofulvin; Heme; Male; Mice; Superoxide Dismutase | 2014 |
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Animals; Disease Models, Animal; Extracellular Space; Heme; Humans; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Neutrophil Activation; Neutrophils | 2014 |
Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dapsone; Disease Models, Animal; Erythrocyte Transfusion; Erythrocytes; Heme; Liver; Liver Function Tests; Male; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic | 2014 |
Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice.
Topics: Anemia, Hemolytic, Congenital; Animals; Bone Marrow Transplantation; Disease Models, Animal; Female; Heme; Heme Oxygenase-1; Humans; Iron; Kidney; Kupffer Cells; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress | 2014 |
Heme Oxygenase Improves Renal Function by Potentiating Podocyte-Associated Proteins in Nω-Nitro-l-Arginine-Methyl Ester (l-NAME)-Induced Hypertension.
Topics: Animals; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Heme; Heme Oxygenase (Decyclizing); Hypertension; Inflammation Mediators; Kidney; Male; Mesoporphyrins; NG-Nitroarginine Methyl Ester; Oxidative Stress; Podocytes; Rats, Sprague-Dawley; Signal Transduction | 2015 |
Novel insights in mammalian catalase heme maturation: effect of NO and thioredoxin-1.
Topics: Animals; Antioxidants; Asthma; Catalase; Cell Line; Disease Models, Animal; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); HEK293 Cells; Heme; Humans; Lung; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nitric Oxide; Ovalbumin; Thioredoxins | 2015 |
A new method to image heme-Fe, total Fe, and aggregated protein levels after intracerebral hemorrhage.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Heme; Iron; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spectrum Analysis, Raman | 2015 |
The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice.
Topics: Anemia, Sickle Cell; Animals; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Endothelium; Erythrocytes; Female; Fucose; Heme; Hemoglobins; Humans; Inflammation; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Neutrophils; NF-kappa B; Vascular Cell Adhesion Molecule-1; Venules | 2015 |
The endosomal sorting complex required for transport machinery influences haem uptake and capsule elaboration in Cryptococcus neoformans.
Topics: Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Fluconazole; Fungal Capsules; Heme; Macrophages; Mice; Mutation; Phenotype; Proteolysis | 2015 |
A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit.
Topics: Alpha-Globulins; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fetal Hemoglobin; Heme; Humans; Kidney Glomerulus; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Rabbits | 2015 |
Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.
Topics: 5-Aminolevulinate Synthetase; Animals; Antioxidants; Cell Death; Cells, Cultured; Disease Models, Animal; Enzyme Induction; Heart Failure; Heme; Humans; Mice, Transgenic; Mitochondria, Heart; Myocardial Infarction; Myocytes, Cardiac; Oxidative Stress; RNA Interference; Signal Transduction; Transfection; Up-Regulation | 2015 |
Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing.
Topics: Alternative Splicing; Anemia, Refractory; Anemia, Sideroblastic; Animals; Disease Models, Animal; Erythrocyte Transfusion; Erythropoiesis; Female; Heme; Hemizygote; Humans; Male; Mutation; Pyridoxine; RNA Splicing; Stem Cell Transplantation; Treatment Outcome | 2015 |
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
Topics: 14-alpha Demethylase Inhibitors; Animals; Chagas Disease; Crystallography, X-Ray; Disease Models, Animal; Female; Heme; Mice; Models, Molecular; Protein Conformation; Pyridines; Sterol 14-Demethylase; Tetrazoles; Trypanocidal Agents; Trypanosoma cruzi | 2016 |
Nonredundant Roles of Iron Acquisition Systems in Vibrio cholerae.
Topics: Animals; Bacterial Proteins; Cholera; Disease Models, Animal; Heme; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Iron; Mice; Mutation; Oxygen; Peptide Synthases; Receptors, Cell Surface; Vibrio cholerae | 2016 |
Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Cell Line; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Deletion; Heme; Hemopexin; Humans; Macrophages; Mice; Mice, Knockout; Reactive Oxygen Species; Toll-Like Receptor 4 | 2016 |
Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case-control study of Ugandan children.
Topics: Animals; Case-Control Studies; Child; Child, Preschool; Disease Models, Animal; Female; Haptoglobins; Heme; Hemoglobins; Hemopexin; Humans; Infant; Malaria, Falciparum; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Plasma; Prospective Studies; Survival Analysis; Uganda | 2015 |
Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.
Topics: Animals; Aortic Aneurysm, Abdominal; Body Weight; Cytokines; Disease Models, Animal; Disease Progression; Enzyme Activation; Gene Expression; Genes, Reporter; Heme; Heme Oxygenase-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Macrophages; Male; Mice; Mice, Knockout; Promoter Regions, Genetic; Swine | 2016 |
The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Azoles; Carrier Proteins; Cytochrome P-450 Enzyme System; Disease Models, Animal; DNA, Fungal; Drug Resistance, Fungal; Ergosterol; Fungal Proteins; Gene Expression Regulation, Fungal; Heme; Heme-Binding Proteins; Hemeproteins; Immunocompromised Host; Mice; Mutation; Pulmonary Aspergillosis | 2016 |
Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model.
Topics: Anemia, Sickle Cell; Animals; Bilirubin; Disease Models, Animal; Haptoglobins; Heme; Hemoglobins; Hemolysis; Hemopexin; Hypoxia; Lung; Mice; Mice, Transgenic; Real-Time Polymerase Chain Reaction | 2016 |
Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; Cells, Cultured; Cholesterol; Coculture Techniques; Disease Models, Animal; Female; Genetic Predisposition to Disease; Heme; Hemopexin; Humans; Inflammation Mediators; Lipoproteins, HDL; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; Reactive Oxygen Species; Signal Transduction | 2016 |
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Helminth Proteins; Heme; Humans; Light; Phenothiazines; Pigments, Biological; Planarians; Porphyria, Acute Intermittent; Porphyrins; Skin Pigmentation; Starvation | 2016 |
Induction of Heme Oxygenase-1 Attenuates the Severity of Sepsis in a Non-Surgical Preterm Mouse Model.
Topics: Animals; Body Weight; Chemokine CCL5; Chemokine CXCL10; Cytokines; Disease Models, Animal; Heme; Heme Oxygenase-1; Interleukin-1beta; Mice; Sepsis | 2017 |
The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6.
Topics: Alleles; Animals; ATP-Binding Cassette Transporters; Biological Transport; Cell Membrane; Cohort Studies; Disease Models, Animal; Exome Sequencing; Female; Heme; Humans; Isoantigens; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Porphyrias; Porphyrins; Sequence Homology, Amino Acid; Severity of Illness Index | 2016 |
Distinct Prominent Roles for Enzymes of Plasmodium berghei Heme Biosynthesis in Sporozoite and Liver Stage Maturation.
Topics: Animals; Anopheles; Bacterial Proteins; Disease Models, Animal; Female; Gene Expression Profiling; Heme; Life Cycle Stages; Liver; Mice; Mice, Inbred C57BL; Oocysts; Plasmodium berghei; Real-Time Polymerase Chain Reaction; Sporozoites | 2016 |
Colorectal Carcinogenesis in the A/J Min/+ Mouse Model is Inhibited by Hemin, Independently of Dietary Fat Content and Fecal Lipid Peroxidation Rate.
Topics: Animals; Biomarkers; Carcinogenesis; Colorectal Neoplasms; Dietary Fats; Disease Models, Animal; Feces; Female; Heme; Lipid Peroxidation; Male; Mice; Tumor Burden | 2016 |
Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
Topics: Adaptation, Biological; Anemia, Iron-Deficiency; Animals; Basic-Leucine Zipper Transcription Factors; Blood Cells; Bone Marrow Cells; Cluster Analysis; Diet; Disease Models, Animal; DNA Methylation; Erythroblasts; Gene Expression Profiling; Gene Expression Regulation; Globins; Heme; Iron; Mice; Mice, Knockout; Mitophagy; Protein Binding; Signal Transduction | 2017 |
PPE Surface Proteins Are Required for Heme Utilization by Mycobacterium tuberculosis.
Topics: Animals; Bacterial Proteins; Disease Models, Animal; DNA Transposable Elements; Gene Deletion; Heme; Membrane Proteins; Mice, Inbred C57BL; Mutagenesis, Insertional; Mycobacterium tuberculosis; Protein Binding; Surface Plasmon Resonance; Tuberculosis; Virulence | 2017 |
Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model.
Topics: Anemia, Hemolytic; Animals; Apoptosis; Biological Transport; Biomarkers; Disease Models, Animal; Erythrocytes; Erythropoiesis; Gene Expression; Heme; Hepatocytes; Hepcidins; Humans; Iron; Iron Overload; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Spleen; Stress, Physiological | 2017 |
Erectile Dysfunction in Heme-Deficient Nitric Oxide-Unresponsive Soluble Guanylate Cyclase Knock-In Mice.
Topics: Animals; Cyclic GMP; Disease Models, Animal; Erectile Dysfunction; Guanylate Cyclase; Heme; Humans; Male; Mice; Nitric Oxide; Penile Erection; Penis; Soluble Guanylyl Cyclase | 2017 |
Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload.
Topics: Animals; Bilirubin; Blotting, Western; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Ferritins; Heme; Heme Oxygenase-1; Hemolysis; Hemopexin; Immunohistochemistry; Liver Diseases; Mice; Mice, Mutant Strains | 2008 |
Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Induction; Heme; Heme Oxygenase-1; Hypertension; Infusion Pumps; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Spectrophotometry; Treatment Outcome | 2008 |
Manifestation of psychiatric behaviors in a mouse model of griseofulvin-induced hepatic porphyria.
Topics: Animals; Anxiety; Behavior, Animal; Cytochrome P-450 Enzyme System; Depression; Disease Models, Animal; Enzymes; Feces; Griseofulvin; Heme; Liver; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Porphyrias, Hepatic; Swimming | 2008 |
Heme-hemopexin complex attenuates neuronal cell death and stroke damage.
Topics: Animals; Blotting, Western; Brain; Cell Death; Cell Line; Disease Models, Animal; Heme; Heme Oxygenase-1; Hemopexin; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Neurons; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Heme arginate suppresses cardiac lesions and hypertrophy in deoxycorticosterone acetate-salt hypertension.
Topics: Animals; Arginine; Cardiomegaly; Desoxycorticosterone; Disease Models, Animal; Heart; Heart Diseases; Heme; Heme Oxygenase (Decyclizing); Hypertension; Hypertrophy, Left Ventricular; Male; MAP Kinase Kinase 4; Mesoporphyrins; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Transforming Growth Factor beta | 2009 |
The heme-binding protein (HbpA) of Haemophilus influenzae as a virulence determinant.
Topics: Animals; Animals, Newborn; Bacteremia; Bacterial Proteins; Carrier Proteins; Chinchilla; Disease Models, Animal; Female; Haemophilus influenzae; Heme; Humans; Lipoproteins; Mutagenesis, Insertional; Otitis Media; Pregnancy; Rats; Virulence | 2009 |
Longitudinal study of a mouse model of familial porphyria cutanea tarda.
Topics: Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Genotype; Glutathione Transferase; Heme; Hemochromatosis Protein; Histocompatibility Antigens Class I; Liver; Longitudinal Studies; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins; Porphyria Cutanea Tarda; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 2009 |
Hepatic damage and oxidative stress induced by Griseofulvin in mice.
Topics: Animals; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Disease Models, Animal; Griseofulvin; Heme; Heme Oxygenase (Decyclizing); Immunohistochemistry; Liver; Male; Mice; Oxidative Stress; Protoporphyria, Erythropoietic; Protoporphyrins; Tryptophan Oxygenase | 2009 |
Assessing the contribution of heme-iron acquisition to Staphylococcus aureus pneumonia using computed tomography.
Topics: Animals; Disease Models, Animal; Heme; Mice; Mice, Inbred BALB C; Pneumonia, Bacterial; Staphylococcus aureus; Tomography, X-Ray Computed | 2009 |
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant.
Topics: Animals; Antimicrobial Cationic Peptides; Blotting, Western; Carbon-Sulfur Lyases; Coproporphyrinogen Oxidase; Disease Models, Animal; Ferrochelatase; Frataxin; Friedreich Ataxia; Gene Expression Profiling; Heme; Hepcidins; Humans; Iron; Iron-Binding Proteins; Kidney; Liver; Mice; Mice, Knockout; Mitochondria; Myocardium; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Uroporphyrinogen III Synthetase | 2009 |
The porphyrias: clinic, diagnostics, novel investigative tools and evolving molecular therapeutic strategies.
Topics: Animals; Disease Models, Animal; Enzyme Replacement Therapy; Genetic Therapy; Heme; Humans; Porphyrias; Skin Diseases, Genetic | 2010 |
[Effect of L-arginine on pro- and antioxidant status of the rat vessels and lungs in experimental rhabdomyolysis].
Topics: Animals; Antioxidants; Arginine; Blood Vessels; Catalase; Disease Models, Animal; Glycerol; Heme; Heme Oxygenase (Decyclizing); Lung; Male; Nitric Oxide Donors; Protein Carbonylation; Rats; Rats, Wistar; Rhabdomyolysis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2009 |
Cytochrome P450 induction by phenobarbital exacerbates warm hepatic ischemia-reperfusion injury in rat livers.
Topics: Alanine Transaminase; Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Catalase; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Disease Models, Animal; Enzyme Induction; Glutathione; Heme; Lipid Peroxidation; Liver; Liver Diseases; Male; Membrane Proteins; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidative Stress; Phenobarbital; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Warm Ischemia | 2010 |
Heme arginate therapy enhanced adiponectin and atrial natriuretic peptide, but abated endothelin-1 with attenuation of kidney histopathological lesions in mineralocorticoid-induced hypertension.
Topics: Adiponectin; Animals; Arginine; Atrial Natriuretic Factor; Blood Pressure; Blotting, Western; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Heme; Heme Oxygenase (Decyclizing); Hypertension; Kidney; Kidney Diseases; Male; Mineralocorticoids; Rats; Rats, Sprague-Dawley | 2010 |
[The anti-athetotic effects of heme-L-lysinate in a rabbit model of atherosclerosis].
Topics: Animals; Atherosclerosis; Carbon Monoxide; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Heme; Heme Oxygenase-1; HSC70 Heat-Shock Proteins; Lysine; Male; Rabbits; RNA, Messenger | 2010 |
Tin chloride enhances parvalbumin-positive interneuron survival by modulating heme metabolism in a model of cerebral ischemia.
Topics: Animals; Avoidance Learning; Brain Ischemia; Cell Survival; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Hippocampus; Interneurons; Male; Memory Disorders; Metalloporphyrins; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parvalbumins; Rats; Rats, Wistar; Tin Compounds | 2011 |
Breaking down haem attenuates acute pancreatitis: a new treatment option?
Topics: Acute Disease; Animals; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Hemin; Humans; Pancreatitis | 2011 |
Selective brain cooling in rats ameliorates intracerebral hemorrhage and edema caused by penetrating brain injury: possible involvement of heme oxygenase-1 expression.
Topics: Animals; Body Water; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Down-Regulation; Head Injuries, Penetrating; Heme; Heme Oxygenase (Decyclizing); Hypothermia, Induced; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Up-Regulation | 2011 |
CodY regulation is required for full virulence and heme iron acquisition in Bacillus anthracis.
Topics: Animals; Anthrax; Bacillus anthracis; Bacterial Proteins; Base Sequence; Disease Models, Animal; DNA, Bacterial; Female; Gene Deletion; Genes, Bacterial; Guinea Pigs; Heme; Iron; Mice; Mutation; Trans-Activators; Transcription Factors; Virulence | 2011 |
Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Cells, Cultured; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Heme; Hemochromatosis; Herpesviridae Infections; Iron; Iron Overload; Male; Membrane Transport Proteins; Metalloporphyrins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muromegalovirus; Proton-Coupled Folate Transporter; Real-Time Polymerase Chain Reaction; Receptors, Virus; Retina; Retinal Pigment Epithelium; RNA, Messenger | 2011 |
Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation.
Topics: Animals; Benzoates; Biphenyl Compounds; Cardiomegaly; Caveolin 3; Cyclic GMP; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Heme; Hydrocarbons, Fluorinated; Hydrolysis; Membrane Microdomains; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Oxidation-Reduction; Protein Transport; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase | 2012 |
Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization.
Topics: Animals; Bacteremia; Cell Movement; Coinfection; Disease Models, Animal; Disease Resistance; Gene Expression; Granulocytes; Heme; Heme Oxygenase-1; Hemin; Hemolysis; Humans; Malaria; Membrane Proteins; Mice; Mice, Inbred C57BL; Phenylhydrazines; Plasmodium yoelii; Respiratory Burst; Salmonella Infections; Salmonella typhimurium | 2011 |
The iron-regulated surface proteins IsdA, IsdB, and IsdH are not required for heme iron utilization in Staphylococcus aureus.
Topics: Animals; Antigens, Bacterial; Arthritis, Infectious; Bacterial Load; Cation Transport Proteins; Disease Models, Animal; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Heme; Iron; Membrane Proteins; Mice; Receptors, Cell Surface; Staphylococcal Infections; Staphylococcus aureus | 2012 |
Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Enzyme Activation; Female; Heme; Hydroxymethylbilane Synthase; Kidney Function Tests; Liver; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Porphyria, Acute Intermittent; Porphyrinogens; Porphyrins; Renal Insufficiency; Sex Factors | 2012 |
Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Heme; Hemoglobins; Humans; Male; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Binding; Protein Interaction Domains and Motifs | 2012 |
Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Glucose; Griseofulvin; Heme; Locomotion; Male; Mice; Mice, Inbred ICR; Porphyrias | 2012 |
Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Erythrocytes; Heme; Heme Oxygenase-1; Hemin; Hemolysis; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Macrophages; Male; Mice; Microglia; Neurons; Rats; Rats, Wistar; Signal Transduction; Subarachnoid Hemorrhage | 2012 |
Impact of intravascular hemolysis in malaria on liver dysfunction: involvement of hepatic free heme overload, NF-κB activation, and neutrophil infiltration.
Topics: Animals; Base Sequence; Blotting, Western; Disease Models, Animal; DNA Primers; Electrophoretic Mobility Shift Assay; Heme; Heme Oxygenase (Decyclizing); Hemolysis; In Situ Nick-End Labeling; Liver; Malaria; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; NF-kappa B; Oxidative Stress; Plasmodium yoelii; Tumor Necrosis Factor-alpha | 2012 |
A functional tonB gene is required for both virulence and competitive fitness in a chinchilla model of Haemophilus influenzae otitis media.
Topics: Animals; Bacterial Proteins; Chinchilla; Disease Models, Animal; Genes, Bacterial; Genetic Fitness; Haemophilus Infections; Haemophilus influenzae; Heme; Membrane Proteins; Mutation; Otitis Media; Otitis Media with Effusion; Virulence | 2012 |
Roles of iron acquisition systems in virulence of extraintestinal pathogenic Escherichia coli: salmochelin and aerobactin contribute more to virulence than heme in a chicken infection model.
Topics: Animal Structures; Animals; Chickens; Disease Models, Animal; Enterobactin; Escherichia coli; Escherichia coli Infections; Gene Deletion; Glucosides; Heme; Histocytochemistry; Hydroxamic Acids; Iron; Microscopy; Virulence Factors | 2012 |
Characterization of the mechanism of protection mediated by CS-D7, a monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB).
Topics: Animals; Antibodies, Bacterial; Antibodies, Monoclonal; Cation Transport Proteins; Complement System Proteins; Disease Models, Animal; Heme; Mice; Mice, Inbred BALB C; Mutant Proteins; Opsonin Proteins; Phagocytosis; Protein Binding; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Survival Analysis | 2012 |
SapF-mediated heme-iron utilization enhances persistence and coordinates biofilm architecture of Haemophilus.
Topics: Adenosine Triphosphatases; Animals; Bacterial Proteins; Biofilms; Carrier State; Chinchilla; Disease Models, Animal; Gene Deletion; Haemophilus Infections; Haemophilus influenzae; Heme; Iron; Nasopharynx; Otitis Media | 2012 |
Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism.
Topics: Adiposity; Animals; Arginine; Chemokine CCL2; Disease Models, Animal; Endothelin-1; Enzyme Activators; Gene Expression; Glucose; Heme; Heme Oxygenase (Decyclizing); Humans; Hyperaldosteronism; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Intra-Abdominal Fat; JNK Mitogen-Activated Protein Kinases; Male; Mesoporphyrins; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor AP-1 | 2012 |
Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.
Topics: Anemia, Sideroblastic; Animals; ATPase Inhibitory Protein; Disease Models, Animal; Erythroblasts; Erythropoiesis; Ferrochelatase; Genetic Complementation Test; Heme; Humans; Hydrogen-Ion Concentration; Mice; Mitochondria; Mitochondrial Proteins; Oxidation-Reduction; Proteins; Zebrafish | 2012 |
Unveiling the association of STAT3 and HO-1 in prostate cancer: role beyond heme degradation.
Topics: Animals; Cell Line, Tumor; Cytoplasm; Disease Models, Animal; Gene Expression; Heme; Heme Oxygenase-1; Humans; Male; Matrix Metalloproteinase 9; Mice; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Binding; Protein Transport; Receptors, Androgen; Signal Transduction; STAT3 Transcription Factor; Transplantation, Heterologous | 2012 |
Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Topics: Allylisopropylacetamide; Animals; Disease Models, Animal; Glucose; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Heme; Liver; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Porphyria, Acute Intermittent; Pyridines; Rats; Reactive Oxygen Species | 2013 |
Iron supplementation increases disease activity and vitamin E ameliorates the effect in rats with dextran sulfate sodium-induced colitis.
Topics: Administration, Oral; Animals; Antioxidants; Colitis; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Drug Interactions; Feces; Gastrointestinal Hemorrhage; Glutathione Peroxidase; Heme; Inflammation; Iron, Dietary; Lipid Peroxidation; Male; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Vitamin E | 2002 |
Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain; Brain Injuries; Cell Count; Disease Models, Animal; Enzyme Activation; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Isoenzymes; Lipid Peroxidation; Male; Membrane Proteins; Mice; Mice, Knockout; Motor Activity; Neurons; Recovery of Function | 2003 |
Competitive and noncompetitive inhibition of myocardial cytochrome C oxidase in sepsis.
Topics: Animals; Binding Sites; Binding, Competitive; Blotting, Northern; Blotting, Western; Cecum; Disease Models, Animal; Electron Transport; Electron Transport Complex IV; Heme; Immunoblotting; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Oxygen; Phosphorylation; RNA, Messenger; Sepsis; Time Factors | 2004 |
Inhibition of heme aggregation by chloroquine reduces Schistosoma mansoni infection.
Topics: Animals; Cell Fractionation; Chloroquine; Cohort Studies; Disease Models, Animal; Drug Design; Female; Heme; Hemeproteins; Injections, Intraperitoneal; Liver; Mice; Parasite Egg Count; Parasitemia; Schistosoma mansoni; Schistosomiasis | 2004 |
[Activity of heme synthesis enzymes in the bone marrow cells of rats with alimentary iron-deficient anemia].
Topics: 5-Aminolevulinate Synthetase; Anemia, Iron-Deficiency; Animals; Bone Marrow Cells; Catalase; Disease Models, Animal; Female; Ferrochelatase; Heme; Malondialdehyde; Porphobilinogen Synthase; Rats; Superoxide Dismutase | 2004 |
Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.
Topics: Aging; Animals; Antifungal Agents; Cholestasis; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Griseofulvin; Heme; Hemeproteins; Immunoblotting; Liver; Male; Mice; Protoporphyria, Erythropoietic; Protoporphyrins; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Heme-regulated eIF2alpha kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and beta-thalassemia.
Topics: Animals; beta-Thalassemia; Disease Models, Animal; eIF-2 Kinase; Erythrocytes; Eukaryotic Initiation Factor-2; Globins; Heat Stress Disorders; Heme; Humans; Mice; Mice, Knockout; Oxidative Stress; Phenotype; Protein Biosynthesis; Protoporphyria, Erythropoietic | 2005 |
Response of glucose metabolism enzymes in an acute porphyria model. Role of reactive oxygen species.
Topics: Allylisopropylacetamide; Animals; Dicarbethoxydihydrocollidine; Disease Models, Animal; Female; Glucose; Heme; Lipid Peroxidation; Liver; Luminescent Measurements; Porphyria, Acute Intermittent; Rats; Rats, Wistar; Reactive Oxygen Species; Urine | 2005 |
The effectiveness of oral tin mesoporphyrin prophylaxis in reducing bilirubin production after an oral heme load in a transgenic mouse model.
Topics: Animals; Bilirubin; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Hyperbilirubinemia; Metalloporphyrins; Mice; Mice, Transgenic; Transcription, Genetic | 2006 |
Carbon monoxide pretreatment prevents respiratory derangement and ameliorates hyperacute endotoxic shock in pigs.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood Coagulation; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Intercellular Adhesion Molecule-1; Interleukin-10; Lipopolysaccharides; Lung; Models, Biological; Oxygen; Respiration Disorders; Shock, Septic; Swine; Up-Regulation | 2005 |
Cytosolic persistence of mouse brain CYP1A1 in chronic heme deficiency.
Topics: Animals; beta-Naphthoflavone; Brain; Chronic Disease; Cytochrome P-450 CYP1A1; Cytosol; Disease Models, Animal; Enzyme Inhibitors; Female; Genotype; Heme; Hydroxymethylbilane Synthase; Liver; Metabolism, Inborn Errors; Mice; Molecular Sequence Data; RNA, Messenger; Subcellular Fractions | 2005 |
Heme transport contributes to in vivo fitness of Bordetella pertussis during primary infection in mice.
Topics: Animals; Bacterial Proteins; Biological Transport; Bordetella Infections; Bordetella pertussis; Disease Models, Animal; Gene Expression Regulation, Bacterial; Heme; Mice | 2006 |
PEGylated albumin-heme as an oxygen-carrying plasma expander: Exchange transfusion into acute anemia rat model.
Topics: Acute Disease; Albumins; Anemia; Animals; Blood Pressure; Blood Substitutes; Disease Models, Animal; Heart Rate; Heme; Oxygen; Polyethylene Glycols; Rats | 2006 |
Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat.
Topics: Animals; Bilirubin; Blotting, Western; Cadmium Chloride; Colitis, Ulcerative; Disease Models, Animal; Enzyme Inhibitors; Heme; Heme Oxygenase-1; Male; Metalloporphyrins; Peroxidase; Protoporphyrins; Rats; Rats, Wistar; Up-Regulation | 2007 |
Ursodesoxycholic acid and heme-arginate are unable to improve hematopoiesis and liver injury in an erythropoietic protoporphyria mouse model.
Topics: Animals; Arginine; Cholagogues and Choleretics; Disease Models, Animal; Hematopoiesis; Heme; Injections, Intraperitoneal; Liver; Mice; Mice, Transgenic; Protoporphyria, Erythropoietic; Ursodeoxycholic Acid | 2006 |
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Plasmodium berghei | 2007 |
Lipoprotein e (P4) of Haemophilus influenzae: role in heme utilization and pathogenesis.
Topics: Animals; Bacteremia; Bacterial Outer Membrane Proteins; Culture Media; Disease Models, Animal; Esterases; Female; Haemophilus Infections; Haemophilus influenzae; Heme; Humans; Lipoproteins; Pregnancy; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Virulence | 2007 |
Heme moves to center stage in cerebral malaria.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Malaria, Cerebral; Mice | 2007 |
Blood pressure-independent effect of long-term treatment with the soluble heme-independent guanylyl cyclase activator HMR1766 on progression in a model of noninflammatory chronic renal damage.
Topics: Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Guanylate Cyclase; Heme; Kidney Failure, Chronic; Male; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfonamides; Time | 2007 |
Carbon monoxide can prevent acute lung injury observed after ischemia reperfusion of the lower extremities.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bilirubin; Blood Pressure; Carbon Monoxide; Coloring Agents; Disease Models, Animal; Drug Therapy, Combination; Evans Blue; Heme; Hindlimb; Male; Pulmonary Edema; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Severity of Illness Index | 2007 |
Heme oxygenase-1 inducer hemin prevents vascular thrombosis.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Blood Pressure; Carotid Arteries; Carotid Artery Injuries; Carotid Artery Thrombosis; Disease Models, Animal; Electric Stimulation; Enzyme Induction; Enzyme Inhibitors; Fibrinolytic Agents; Heme; Heme Oxygenase (Decyclizing); Hemin; Leukocyte Count; Male; Metalloporphyrins; Platelet Count; Protoporphyrins; Rats; Rats, Wistar; RNA, Messenger; Severity of Illness Index; Time Factors | 2007 |
Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Aminolevulinic Acid; Animals; Cytochrome P-450 CYP1A2; Disease Models, Animal; Environmental Pollutants; Female; Gene Expression; Gene Expression Profiling; Gene Silencing; Heme; Iron Overload; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Oxidative Stress; Polychlorinated Dibenzodioxins; Porphyria Cutanea Tarda; Receptors, Aryl Hydrocarbon; Up-Regulation; Uroporphyrins | 2008 |
Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice.
Topics: Animals; Antimicrobial Cationic Peptides; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Disease Models, Animal; eIF-2 Kinase; Genotype; Heme; Hemochromatosis; Hepcidins; Iron; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Protein Serine-Threonine Kinases; Spleen; Transforming Growth Factor beta | 2008 |
An experimental model of postnatal jaundice in the suckling rat. Suppression of induced hyperbilirubinemia by Sn-protoporphyrin.
Topics: Aging; Aminolevulinic Acid; Animals; Bilirubin; Disease Models, Animal; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
Achieving and maintaining moderate iron deficiency in rats.
Topics: Aging; Animals; Diet; Disease Models, Animal; Heme; Hemoglobinometry; Iron Deficiencies; Male; Protoporphyrins; Rats | 1981 |
Development of a rat model for iron deficiency and toxicological studies: comparison among Fischer 344, Wistar, and Sprague Dawley strains.
Topics: Anemia, Iron-Deficiency; Animals; Diet; Dietary Carbohydrates; Disease Models, Animal; Heme; Hemoglobins; Iron; Iron Deficiencies; Liver; Male; Protoporphyrins; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Starch; Sucrose | 1995 |
Targets of nitric oxide in a mouse model of liver inflammation by Corynebacterium parvum.
Topics: Animals; Arginine; Blood; Blotting, Western; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Inflammation; Liver; Liver Diseases; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1995 |
Quantitative evaluation of heme biosynthetic pathway parameters as biomarkers of low-level lead exposure in rats.
Topics: Analysis of Variance; Animals; Biomarkers; Coproporphyrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Erythrocytes; Heme; Lead; Lead Poisoning; Male; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Inbred F344; Spectrophotometry, Atomic; Water Pollutants, Chemical | 1995 |
Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer--prolonged animal survival.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Cricetinae; Disease Models, Animal; Female; Heme; Injections, Intravenous; Lasers; Mesocricetus; Microscopy, Fluorescence; Neoplasm Transplantation; Pancreatic Neoplasms; Photochemotherapy; Protoporphyrins; Sensitivity and Specificity; Time Factors | 1994 |
Azidothymidine (AZT)-induced siderosis.
Topics: Animals; Disease Models, Animal; Heme; HIV Infections; Iron; Liver; Macrophages; Mice; Mice, Inbred Strains; Siderosis; Zidovudine | 1993 |
Alcohol mediates increases in hepatic and serum nonheme iron stores in a rat model for alcohol-induced liver injury.
Topics: Alcoholism; Animals; Disease Models, Animal; Fatty Liver, Alcoholic; Heme; Humans; Iron; Liver; Liver Diseases, Alcoholic; Male; Molecular Weight; Rats; Rats, Sprague-Dawley | 1996 |
MR detection of hyperacute parenchymal hemorrhage of the brain.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Brain; Cerebral Hemorrhage; Cerebrovascular Disorders; Child; Child, Preschool; Disease Models, Animal; Female; Ferritins; Hematoma; Heme; Humans; Iron; Magnetic Resonance Imaging; Male; Middle Aged; Rats; Retrospective Studies | 1998 |
Evidence for and consequences of chronic heme deficiency in Belgrade rat reticulocytes.
Topics: Anemia, Hypochromic; Animals; Cell-Free System; Cycloheximide; Disease Models, Animal; Heme; Heptanoates; Iron; Rats; Reticulocytes | 1999 |
Spontaneous porphyria of the Long-evans cinnamon rat: an animal model of Wilson's disease.
Topics: Aging; Animals; Bone Marrow; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Heme; Hepatolenticular Degeneration; Humans; Kidney; Liver; Male; Microscopy, Fluorescence; Porphyrias; Porphyrins; Rats; Rats, Inbred LEC; Sex Characteristics; Spleen | 2000 |
Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific delta-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome.
Topics: 5-Aminolevulinate Synthetase; Animals; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Kidney; Lipopolysaccharides; Liver; Male; Multiple Organ Failure; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Time Factors | 2000 |
NO-independent regulatory site on soluble guanylate cyclase.
Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Cyclic N-Oxides; Cysteine; Disease Models, Animal; Enzyme Activation; Female; Guanylate Cyclase; Heme; Humans; Imidazoles; In Vitro Techniques; Indazoles; Molecular Sequence Data; Nitric Oxide; Photoaffinity Labels; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Rats; Solubility | 2001 |
Carboxyhemoglobin and lactate levels do not correlate in critically ill patients.
Topics: Animals; Biomarkers; Blood Gas Analysis; Carboxyhemoglobin; Critical Illness; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Humans; Hypoxia; Lactic Acid; Rats; Sepsis | 1999 |
TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouse.
Topics: Animals; Bacterial Proteins; Biological Transport; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Heme; Hydroxamic Acids; Iron; Membrane Proteins; Mice; Mutagenesis; Siderophores; Urinary Tract Infections; Virulence | 2001 |
A rabbit reticulocyte model for the role of hemin-controlled repressor in hypochromic anemias.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Anemia, Hypochromic; Animals; Cell-Free System; Chelating Agents; Disease Models, Animal; Ethanol; Genes, Regulator; Glutathione; Heme; Hemin; Kinetics; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Transfer | 1976 |
Drug-induced exacerbations of porphyria.
Topics: Alkylating Agents; Analgesics; Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Central Nervous System Stimulants; Chick Embryo; Disease Models, Animal; Heme; Humans; Hypnotics and Sedatives; Hypoglycemic Agents; Liver; Porphyrias; Psychotropic Drugs; Tranquilizing Agents | 1976 |
Experimental porphyrias as models for human hepatic porphyrias.
Topics: Animals; Disease Models, Animal; Heme; Humans; Iron; Liver Diseases; Porphyrias; Rats; Uroporphyrinogen Decarboxylase | 1977 |
The effects of anemia on heme synthesis parameters during lead exposure.
Topics: Anemia, Hypochromic; Animals; Disease Models, Animal; Environmental Exposure; Heme; Lead; Papio | 1976 |
The effect of environmental light exposure on drug-induced porphyria in the rat.
Topics: Animals; Dicarbethoxydihydrocollidine; Disease Models, Animal; Heme; Light; Male; Porphyrias; Porphyrins; Rats; Skin | 1976 |
Iron speciation in hypotransferrinaemic mouse serum.
Topics: Animals; Disease Models, Animal; Female; Heme; Homozygote; Iron; Liver; Male; Mice; Mice, Mutant Strains; Transferrin | 1991 |
Heme overload inhibits the growth of normal rats.
Topics: Anemia, Hemolytic; Animals; Disease Models, Animal; Growth; Heme; Injections, Intraperitoneal; Rats; Rats, Inbred Strains | 1989 |
Carbon monoxide excretion as an index of bilirubin production in rhesus monkeys.
Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Hemolysis; Hyperbilirubinemia; Macaca; Macaca mulatta; Metalloporphyrins; Protoporphyrins | 1989 |
The role of iron in the hexachlorobenzene induced porphyria. I. Studies on different types of iron and its relation with porphyrinogen carboxy-lyase decrease.
Topics: Animals; Carboxy-Lyases; Chlorobenzenes; Disease Models, Animal; Female; Heme; Hexachlorobenzene; Iron; Liver; Porphyrias; Rats; Rats, Inbred Strains; Uroporphyrinogen Decarboxylase | 1985 |
Elevated brain tryptophan and enhanced 5-hydroxytryptamine turnover in acute hepatic heme deficiency: clinical implications.
Topics: Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Heme; Liver; Liver Diseases; Male; Morphine; Porphyrias; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1985 |
Effect of blood on the activity and persistence of antigen induced inflammation in the rat air pouch.
Topics: Air; Animals; Antigens; Blood; Disease Models, Animal; Granulation Tissue; Heme; Hypersensitivity; Inflammation; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1985 |
Lead toxicity: a problem in environmental pathology.
Topics: Animals; Cell Nucleus; Central Nervous System Diseases; Disease Models, Animal; Environmental Exposure; Environmental Health; Hematologic Diseases; Heme; Housing; Humans; Inclusion Bodies; Kidney; Kidney Diseases; Lead; Lead Poisoning; Microscopy, Electron; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Paint; Pyruvates; Rats; Succinates | 1971 |
Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism.
Topics: Adaptation, Physiological; Animals; Bilirubin; Bone Marrow; Cycloheximide; Dactinomycin; Disease Models, Animal; Enzyme Induction; Female; Heme; Hemoglobins; Hemoglobinuria; Homeostasis; Injections, Intravenous; Iron Isotopes; Kidney Tubules; Liver; NADP; Oxygenases; Protein Biosynthesis; Puromycin; Rats; RNA; Spleen | 1971 |
Effect of hypoxia on degradation of mitochondrial components in rat cardiac muscle.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Cell Membrane; Coronary Disease; Cytochromes; Disease Models, Animal; Female; Heme; Hydrogen-Ion Concentration; Hypoxia; Ischemia; Lactates; Mitochondria, Muscle; Muscle Proteins; Myocardium; Oxygen; Oxygen Consumption; Pyruvates; Rats; Tritium | 1971 |