Page last updated: 2024-08-23

heme and Chagas Disease

heme has been researched along with Chagas Disease in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Fielding, AJ; Freeman, SL; Inchausti, L; Issoglio, FM; Kwon, H; Martínez, A; Moody, PCE; Piacenza, L; Radi, R; Raven, EL; Skafar, V; Smircich, P; Zeida, A1
Costa Dos Santos Junior, G; de Almeida Nogueira, NP; Paes, MC; Pinheiro Aguiar, R; Silva Dias Vieira, C1
Alcocer, M; Coelho, VL; Dias, FA; Nogueira, NP; Paes, MC; Pane, A; Rossini, A; Sang, F; Saraiva, FMS; Vieira, CSD1
Cricco, JA; Merli, ML; Pagura, L; Tevere, E1
Almeida-Amaral, EE; Inacio, JDF; Laranja, GAT; Mendonça, APM; Menna-Barreto, RF; Nogueira, NP; Oliveira, MF; Oliveira, MP; Paes, MC; Saraiva, FMS; Torres, EJL1
Aktas, BH; Dias-Teixeira, KL; Dos Santos Neto, JV; Franco, CH; Lopes, UG; Machado, FC; Moraes, CB; Schenkman, S1
Azambuja, P; Bourguignon, SC; Ferreira, CM; Gandara, ACP; Gonzalez, MS; Lechuga, GC; Menna-Barreto, RFS; Oliveira, MF; Paes, MC; Paiva-Silva, GO; Saraiva, FM; Stiebler, R; Walter-Nuno, AB1
Almendares, O; Dotson, EM; Lowenberger, C; Oliveira, PL; Paiva-Silva, GO; Pennington, PM; Taracena, ML; Umaña, C1
da Gama Jaen Batista, D; da Silva, CF; Hargrove, TY; Hoekstra, WJ; Lepesheva, GI; Nefertiti, AS; Rachakonda, G; Schotzinger, RJ; Soeiro, Mde N; Villalta, F; Wawrzak, Z1
Carneiro, AB; Costa, SC; Laranja, GA; Paes, MC; Silva-Neto, MA; Silveira, AB; Souza, CF1
Bechara, EJ; Demasi, M; Oliveira, PL; Petretski, JH; Souza, AV1

Other Studies

12 other study(ies) available for heme and Chagas Disease

ArticleYear
Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:8

    Topics: Antioxidants; Ascorbate Peroxidases; Ascorbic Acid; Chagas Disease; Cytochrome-c Peroxidase; Cytochromes c; Heme; Humans; Peroxidase; Peroxidases; Substrate Specificity; Trypanosoma cruzi

2022
Glucose metabolism sustains heme-induced Trypanosoma cruzi epimastigote growth in vitro.
    PLoS neglected tropical diseases, 2023, Volume: 17, Issue:11

    Topics: Animals; Chagas Disease; Glucose; Heme; Humans; Mammals; Succinates; Trypanosoma cruzi

2023
Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:1

    Topics: Animals; Chagas Disease; Gene Expression Profiling; Genes, Mitochondrial; Glucose; Heme; Insect Vectors; Microbodies; Signal Transduction; Transcription, Genetic; Triatominae; Trypanosoma cruzi

2020
A new model for
    The Journal of biological chemistry, 2020, 09-18, Volume: 295, Issue:38

    Topics: Chagas Disease; Heme; Homeostasis; Humans; Models, Biological; Protozoan Proteins; Trypanosoma cruzi

2020
Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production.
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Growth Processes; Cells, Cultured; Chagas Disease; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Heme; Humans; Life Cycle Stages; Membrane Potential, Mitochondrial; Mitochondria; Organophosphorus Compounds; Oxygen Consumption; Piperidines; Reactive Oxygen Species; Rhodamines; Trypanosoma cruzi

2017
Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation.
    Scientific reports, 2018, 03-20, Volume: 8, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Chagas Disease; eIF-2 Kinase; Eukaryotic Initiation Factor-2; G1 Phase; Heme; Humans; Myoblasts; Parasitic Sensitivity Tests; Phosphorylation; Protozoan Proteins; Rats; Trypanosoma brucei brucei; Trypanosoma cruzi; Urea

2018
Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:7

    Topics: Animals; Chagas Disease; Crystallization; Female; Heme; Humans; Insect Vectors; Male; Oviposition; Oxidation-Reduction; Rhodnius; Trypanosoma cruzi

2018
Genetically modifying the insect gut microbiota to control Chagas disease vectors through systemic RNAi.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:2

    Topics: Animals; Carrier Proteins; Catalase; Chagas Disease; Escherichia coli; Female; Gastrointestinal Microbiome; Gastrointestinal Tract; Gene Knockdown Techniques; Genetic Vectors; Heme; Heme-Binding Proteins; Hemeproteins; Insect Control; Insect Vectors; Rhodnius; RNA Interference; RNA, Double-Stranded; RNA, Small Interfering; Trypanosoma cruzi

2015
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:2

    Topics: 14-alpha Demethylase Inhibitors; Animals; Chagas Disease; Crystallography, X-Ray; Disease Models, Animal; Female; Heme; Mice; Models, Molecular; Protein Conformation; Pyridines; Sterol 14-Demethylase; Tetrazoles; Trypanocidal Agents; Trypanosoma cruzi

2016
Heme-induced Trypanosoma cruzi proliferation is mediated by CaM kinase II.
    Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3

    Topics: Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Proliferation; Chagas Disease; Heme; Humans; Protein Kinase Inhibitors; Sulfonamides; Triatominae; Trypanosoma cruzi

2009
Urate protects a blood-sucking insect against hemin-induced oxidative stress.
    Free radical biology & medicine, 1997, Volume: 22, Issue:1-2

    Topics: Animals; Chagas Disease; Free Radical Scavengers; Heme; Hemin; Hemoglobins; Hemolymph; Hydrolysis; Insect Vectors; Organ Culture Techniques; Oxidative Stress; Rhodnius; Thiobarbituric Acid Reactive Substances; Uric Acid

1997
New leads for trypanosomiasis chemotherapy.
    Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101

    Topics: Chagas Disease; Drug Therapy, Combination; Heme; Humans; Melarsoprol; Naphthoquinones; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African

1978